{"id":"https://openalex.org/W3024567735","doi":"https://doi.org/10.1177/0141076820918236","title":"Loneliness, social isolation, cardiovascular disease and mortality: a synthesis of the literature and conceptual framework","display_name":"Loneliness, social isolation, cardiovascular disease and mortality: a synthesis of the literature and conceptual framework","publication_year":2020,"publication_date":"2020-05-01","ids":{"openalex":"https://openalex.org/W3024567735","doi":"https://doi.org/10.1177/0141076820918236","mag":"3024567735","pmid":"https://pubmed.ncbi.nlm.nih.gov/32407646","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7366328"},"language":"en","primary_location":{"id":"doi:10.1177/0141076820918236","doi":"https://doi.org/10.1177/0141076820918236","is_oa":true,"landing_page_url":"https://doi.org/10.1177/0141076820918236","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/0141076820918236","source":{"id":"https://openalex.org/S49645005","display_name":"Journal of the Royal Society of Medicine","issn_l":"0141-0768","issn":["0141-0768","1758-1095"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Royal Society of Medicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://journals.sagepub.com/doi/pdf/10.1177/0141076820918236","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037452923","display_name":"Sam Hodgson","orcid":"https://orcid.org/0000-0002-5610-850X","observed_orcids":["https://orcid.org/0000-0002-5610-850X"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Sam Hodgson","raw_affiliation_strings":["Division of Primary Care, Population Sciences and Medical Education, University of Southampton, Hampshire SO16 5ST, UK"],"raw_orcid":"https://orcid.org/0000-0002-5610-850X","affiliations":[{"raw_affiliation_string":"Division of Primary Care, Population Sciences and Medical Education, University of Southampton, Hampshire SO16 5ST, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058181002","display_name":"Isabella V C Watts","orcid":"https://orcid.org/0000-0003-1974-2365","observed_orcids":["https://orcid.org/0000-0003-1974-2365"]},"institutions":[{"id":"https://openalex.org/I1310053265","display_name":"St George's Hospital","ror":"https://ror.org/0001ke483","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1310053265","https://openalex.org/I2801196673"]},{"id":"https://openalex.org/I2801196673","display_name":"St George\u2019s University Hospitals NHS Foundation Trust","ror":"https://ror.org/039zedc16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801196673"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Isabella Watts","raw_affiliation_strings":["Foundation Doctor, St. George\u2019s University Hospital, London SW17 0QT, UK"],"raw_orcid":"https://orcid.org/0000-0003-1974-2365","affiliations":[{"raw_affiliation_string":"Foundation Doctor, St. George\u2019s University Hospital, London SW17 0QT, UK","institution_ids":["https://openalex.org/I1310053265","https://openalex.org/I2801196673"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091132477","display_name":"Simon DS Fraser","orcid":"https://orcid.org/0000-0002-4172-4406","observed_orcids":["https://orcid.org/0000-0002-4172-4406"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Simon Fraser","raw_affiliation_strings":["Division of Primary Care, Population Sciences and Medical Education, University of Southampton, Hampshire SO16 5ST, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Primary Care, Population Sciences and Medical Education, University of Southampton, Hampshire SO16 5ST, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074811213","display_name":"Paul Roderick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul Roderick","raw_affiliation_strings":["Division of Primary Care, Population Sciences and Medical Education, University of Southampton, Hampshire SO16 5ST, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Primary Care, Population Sciences and Medical Education, University of Southampton, Hampshire SO16 5ST, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031094296","display_name":"Hajira Dambha\u2010Miller","orcid":"https://orcid.org/0000-0003-0175-443X","observed_orcids":["https://orcid.org/0000-0003-0175-443X"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hajira Dambha-Miller","raw_affiliation_strings":["Division of Primary Care, Population Sciences and Medical Education, University of Southampton, Hampshire SO16 5ST, UK"],"raw_orcid":"https://orcid.org/0000-0003-0175-443X","affiliations":[{"raw_affiliation_string":"Division of Primary Care, Population Sciences and Medical Education, University of Southampton, Hampshire SO16 5ST, UK","institution_ids":["https://openalex.org/I43439940"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5037452923"],"corresponding_institution_ids":["https://openalex.org/I43439940"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":2.5691,"has_fulltext":false,"cited_by_count":189,"citation_normalized_percentile":{"value":0.9210084,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"113","issue":"5","first_page":"185","last_page":"192"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10235","display_name":"Health disparities and outcomes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3306","display_name":"Health"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10235","display_name":"Health disparities and outcomes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3306","display_name":"Health"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12521","display_name":"Death Anxiety and Social Exclusion","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/loneliness","display_name":"loneliness","score":1.0},{"id":"https://openalex.org/keywords/social-isolation","display_name":"social isolation","score":1.0},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.8889999985694885},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.9980000257492065},{"id":"https://openalex.org/keywords/conceptual-framework","display_name":"conceptual framework","score":0.621999979019165},{"id":"https://openalex.org/keywords/mediators-and-moderators","display_name":"mediators and moderators","score":0.7170000076293945},{"id":"https://openalex.org/keywords/biological-mechanisms","display_name":"biological mechanisms","score":0.4970000088214874},{"id":"https://openalex.org/keywords/behavioral-mechanisms","display_name":"behavioral mechanisms","score":0.7630000114440918},{"id":"https://openalex.org/keywords/psychological-mechanisms","display_name":"psychological mechanisms","score":0.9729999899864197},{"id":"https://openalex.org/keywords/social-determinants-of-health","display_name":"social determinants of health","score":0.6790000200271606}],"concepts":[{"id":"https://openalex.org/C2779998236","wikidata":"https://www.wikidata.org/wiki/Q223270","display_name":"Loneliness","level":2,"score":0.9625949859619141},{"id":"https://openalex.org/C2776893239","wikidata":"https://www.wikidata.org/wiki/Q1778765","display_name":"Social isolation","level":2,"score":0.7425252795219421},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.5704773664474487},{"id":"https://openalex.org/C2775941552","wikidata":"https://www.wikidata.org/wiki/Q25212305","display_name":"Isolation (microbiology)","level":2,"score":0.5353893041610718},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.5222150087356567},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4920651316642761},{"id":"https://openalex.org/C14224292","wikidata":"https://www.wikidata.org/wiki/Q13600188","display_name":"Conceptual framework","level":2,"score":0.481231689453125},{"id":"https://openalex.org/C2778087770","wikidata":"https://www.wikidata.org/wiki/Q2297111","display_name":"Social support","level":2,"score":0.44028735160827637},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.42340680956840515},{"id":"https://openalex.org/C185874996","wikidata":"https://www.wikidata.org/wiki/Q269699","display_name":"Interdependence","level":2,"score":0.41899359226226807},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.40208667516708374},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.36441877484321594},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3570563793182373},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.20198547840118408},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.17990916967391968},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.15561780333518982},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.09944093227386475},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.09655490517616272},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08456858992576599},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08394360542297363},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D002423","descriptor_name":"Cause of Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003695","descriptor_name":"Delivery of Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006291","descriptor_name":"Health Policy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008132","descriptor_name":"Loneliness","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011050","descriptor_name":"Policy Making","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011584","descriptor_name":"Psychology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012934","descriptor_name":"Social Isolation","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036301","descriptor_name":"Qualitative Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1177/0141076820918236","doi":"https://doi.org/10.1177/0141076820918236","is_oa":true,"landing_page_url":"https://doi.org/10.1177/0141076820918236","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/0141076820918236","source":{"id":"https://openalex.org/S49645005","display_name":"Journal of the Royal Society of Medicine","issn_l":"0141-0768","issn":["0141-0768","1758-1095"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Royal Society of Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7366328","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7366328","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J R Soc Med","raw_type":"Text"},{"id":"pmid:32407646","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32407646","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Royal Society of Medicine","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.soton.ac.uk:441726","doi":null,"is_oa":false,"landing_page_url":"https://eprints.soton.ac.uk/id/eprint/441726/1/Loneliness_Final_1_.docx","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Review"}],"best_oa_location":{"id":"doi:10.1177/0141076820918236","doi":"https://doi.org/10.1177/0141076820918236","is_oa":true,"landing_page_url":"https://doi.org/10.1177/0141076820918236","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/0141076820918236","source":{"id":"https://openalex.org/S49645005","display_name":"Journal of the Royal Society of Medicine","issn_l":"0141-0768","issn":["0141-0768","1758-1095"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Royal Society of Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[{"id":"https://openalex.org/G3416093469","display_name":null,"funder_award_id":"CL-2019-26-003","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G6191340524","display_name":null,"funder_award_id":"ACF-2018-26-002","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G8536483226","display_name":"A multiple methods investigation of the role of patient-practitioner interactions, health behaviours and cardiovascular risk among patients with type 2 diabetes in primary care","funder_award_id":"DRF-2015-08-027","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"}],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W3024567735.pdf"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W292445073","https://openalex.org/W1977570615","https://openalex.org/W1982016451","https://openalex.org/W2004761428","https://openalex.org/W2022496169","https://openalex.org/W2057546532","https://openalex.org/W2092784420","https://openalex.org/W2101196871","https://openalex.org/W2113686547","https://openalex.org/W2116398621","https://openalex.org/W2134833483","https://openalex.org/W2135504732","https://openalex.org/W2138720796","https://openalex.org/W2141288445","https://openalex.org/W2151758923","https://openalex.org/W2165243546","https://openalex.org/W2168289525","https://openalex.org/W2336497595","https://openalex.org/W2604279332","https://openalex.org/W2725350435","https://openalex.org/W2782215249","https://openalex.org/W2791898602","https://openalex.org/W2801470122","https://openalex.org/W2911711852","https://openalex.org/W2912277723","https://openalex.org/W2928245690","https://openalex.org/W3022903699","https://openalex.org/W4243663932"],"related_works":["https://openalex.org/W3092816668","https://openalex.org/W2004761428","https://openalex.org/W7151248510","https://openalex.org/W7220464153","https://openalex.org/W4310163492","https://openalex.org/W2520095208","https://openalex.org/W2165243546","https://openalex.org/W4396706366","https://openalex.org/W6890180197","https://openalex.org/W2888741001"],"abstract_inverted_index":{"To":[0],"conduct":[1],"a":[2,7,64],"systematic":[3],"review":[4],"and":[5,19,29,47,61,83,112,123,128,141,166],"develop":[6],"conceptual":[8,65,144],"framework":[9,66,99,145],"on":[10,43],"the":[11,53,86,106,133,156],"mechanisms":[12,95],"linking":[13],"loneliness,":[14,44,109,138],"social":[15,45,110,139],"isolation,":[16],"health":[17],"outcomes":[18,163],"mortality.":[20,142],"Electronic":[21],"databases":[22],"were":[23,57,75,96,117],"systematically":[24],"searched":[25],"(PubMed,":[26],"MEDLINE,":[27],"Scopus":[28],"EMBASE)":[30],"from":[31],"inception":[32],"to":[33,40,90,161],"October":[34],"2018":[35],"followed":[36],"by":[37],"manual":[38],"searching":[39],"identify":[41],"research":[42],"isolation":[46,111,140],"mortality":[48,113],"in":[49,52,88,105],"adults":[50],"published":[51],"English":[54],"language.":[55],"Articles":[56],"assessed":[58],"for":[59,164],"quality":[60],"synthesised":[62],"into":[63,119,125],"using":[67],"meta-ethnographical":[68],"approaches.":[69],"A":[70,98],"total":[71],"of":[72,85,149,155],"122":[73],"articles":[74],"included.":[76,97],"These":[77,130],"collated":[78],"observational":[79],"designs":[80],"examining":[81],"mediators":[82],"moderations":[84],"association":[87,107],"addition":[89],"qualitative":[91],"studies":[92],"exploring":[93],"potential":[94],"incorporating":[100],"18":[101],"discrete":[102],"factors":[103,158],"implicated":[104],"between":[108,137],"was":[114],"developed.":[115],"Factors":[116],"categorised":[118],"societal":[120],"or":[121],"individual,":[122],"sub-categorised":[124],"biological,":[126],"behavioural":[127],"psychological.":[129],"findings":[131],"emphasise":[132],"complex":[134],"multidirectional":[135],"relationship":[136],"Our":[143],"may":[146],"allow":[147],"development":[148],"more":[150],"holistic":[151],"interventions,":[152],"targeting":[153],"many":[154],"interdependent":[157],"that":[159],"contribute":[160],"poor":[162],"lonely":[165],"socially":[167],"isolated":[168],"people.":[169]},"counts_by_year":[{"year":2026,"cited_by_count":22},{"year":2025,"cited_by_count":51},{"year":2024,"cited_by_count":50},{"year":2023,"cited_by_count":31},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":19},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-05-21T00:00:00"}