{"id":"https://openalex.org/W3024372978","doi":null,"title":"The ischemic heart: What causes ectopic beating?","display_name":"The ischemic heart: What causes ectopic beating?","publication_year":2005,"publication_date":"2005-12-01","ids":{"openalex":"https://openalex.org/W3024372978","mag":"3024372978"},"language":"en","primary_location":{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:467644","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/467644/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Conf Proc IEEE Eng Med Biol Soc , 7 pp. 7194-7197. (2005)","raw_type":"Article"},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101948840","display_name":"Jie Xiao","orcid":"https://orcid.org/0009-0002-2261-5682","observed_orcids":["https://orcid.org/0009-0002-2261-5682","https://orcid.org/0009-0005-1911-9794"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jie Xiao","raw_affiliation_strings":["Dept. of Biomed. Eng., Tulane Univ., New Orleans, LA"],"raw_orcid":"https://orcid.org/0009-0002-2261-5682","affiliations":[{"raw_affiliation_string":"Dept. of Biomed. Eng., Tulane Univ., New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063002011","display_name":"Benjam\u00edn Roque Rodr\u00edguez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Benjam\u00edn Roque Rodr\u00edguez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5070924694","display_name":"Natalia A. Trayanova","orcid":"https://orcid.org/0000-0002-8661-063X","observed_orcids":["https://orcid.org/0000-0002-8661-063X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Natalia A. Trayanova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.451481,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"7194","last_page":"7197"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.06019999831914902,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myocardial-ischemia","display_name":"myocardial ischemia","score":0.8849999904632568},{"id":"https://openalex.org/keywords/premature-beats","display_name":"extrasystoles","score":0.8980000019073486},{"id":"https://openalex.org/keywords/cardiac-arrhythmia","display_name":"cardiac arrhythmias","score":0.8379999995231628},{"id":"https://openalex.org/keywords/mechanical-stretching","display_name":"mechanical stretch","score":0.8180000185966492},{"id":"https://openalex.org/keywords/l-type-calcium-current","display_name":"L-type calcium current","score":0.9300000071525574},{"id":"https://openalex.org/keywords/spontaneous-electrical-activity","display_name":"spontaneous electrical activity","score":0.7350000143051147}],"concepts":[{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7043668627738953},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.600074827671051},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5333307385444641},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.47411444783210754},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.43221527338027954},{"id":"https://openalex.org/C2993714741","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemic injury","level":3,"score":0.4129719138145447}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:467644","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/467644/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Conf Proc IEEE Eng Med Biol Soc , 7 pp. 7194-7197. (2005)","raw_type":"Article"},{"id":"mag:3024372978","doi":null,"is_oa":false,"landing_page_url":"https://www.neuroscience.ox.ac.uk/publications/286594","pdf_url":null,"source":{"id":"https://openalex.org/S4363608786","display_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","issn_l":"2375-7477","issn":["2375-7477"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["doyens","jufo-1","ki-jl-1","medline","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2919921252","https://openalex.org/W4306767162","https://openalex.org/W2143684860","https://openalex.org/W2146460542","https://openalex.org/W2106605167","https://openalex.org/W2127318338","https://openalex.org/W2136035994","https://openalex.org/W2170102487","https://openalex.org/W2072810255","https://openalex.org/W2072446920"],"abstract_inverted_index":{"The":[0,32,66],"mechanisms":[1],"by":[2],"which":[3,79],"spontaneous":[4,72],"electrical":[5],"activity":[6],"originates":[7],"in":[8,50,75],"the":[9,22,40,44,51,60,76,83,87],"ischemic":[10,52,61,77],"heart":[11],"and":[12],"leads":[13],"to":[14,28,38,64,82],"arrhythmia":[15],"remain":[16],"unknown,":[17],"however":[18],"mechanical":[19],"stretch":[20],"of":[21,34,46,59,86],"diseased":[23],"region":[24],"has":[25],"been":[26],"hypothesized":[27],"play":[29],"a":[30,56],"role.":[31],"goal":[33],"this":[35],"study":[36,67],"is":[37],"investigate":[39],"conditions":[41],"that":[42,69],"favor":[43],"initiation":[45],"stretch-induced":[47,84],"premature":[48],"beats":[49,73],"heart.":[53],"We":[54],"employ":[55],"mathematical":[57],"model":[58],"cell":[62],"subjected":[63],"stretch.":[65],"found":[68],"upon":[70],"stretch,":[71],"occur":[74],"cell,":[78],"are":[80],"due":[81],"re-activation":[85],"L-type":[88],"calcium":[89],"current.":[90]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-05-21T00:00:00"}