{"id":"https://openalex.org/W3024361908","doi":"https://doi.org/10.1016/j.cllc.2020.05.004","title":"Efficacy and Safety of Anti-PD-1 Immunotherapy in Patients Aged \u2265 75 Years With Non\u2013small-cell Lung Cancer (NSCLC): An Italian, Multicenter, Retrospective Study","display_name":"Efficacy and Safety of Anti-PD-1 Immunotherapy in Patients Aged \u2265 75 Years With Non\u2013small-cell Lung Cancer (NSCLC): An Italian, Multicenter, Retrospective Study","publication_year":2020,"publication_date":"2020-05-12","ids":{"openalex":"https://openalex.org/W3024361908","doi":"https://doi.org/10.1016/j.cllc.2020.05.004","mag":"3024361908","pmid":"https://pubmed.ncbi.nlm.nih.gov/32591311"},"language":"en","primary_location":{"id":"doi:10.1016/j.cllc.2020.05.004","doi":"https://doi.org/10.1016/j.cllc.2020.05.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cllc.2020.05.004","pdf_url":null,"source":{"id":"https://openalex.org/S32518486","display_name":"Clinical Lung Cancer","issn_l":"1525-7304","issn":["1525-7304","1938-0690"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Lung Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009884142","display_name":"Andrea Luciani","orcid":"https://orcid.org/0000-0002-9118-2051","observed_orcids":["https://orcid.org/0000-0002-9118-2051"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4396570669","display_name":"Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo","ror":"https://ror.org/03dpchx26","country_code":"IT","type":"government","lineage":["https://openalex.org/I4396570669"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Andrea Luciani","raw_affiliation_strings":["Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy. Electronic address: andrea.luciani@asst.santipaolocarlo.it","Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy. Electronic address: andrea.luciani@asst.santipaolocarlo.it","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4396570669"]},{"raw_affiliation_string":"Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4396570669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089982076","display_name":"Antonio Marra","orcid":"https://orcid.org/0000-0002-7310-7824","observed_orcids":["https://orcid.org/0000-0002-7310-7824"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4396570669","display_name":"Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo","ror":"https://ror.org/03dpchx26","country_code":"IT","type":"government","lineage":["https://openalex.org/I4396570669"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Marra","raw_affiliation_strings":["Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy"],"raw_orcid":"https://orcid.org/0000-0002-7310-7824","affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4396570669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011139663","display_name":"Luca Toschi","orcid":"https://orcid.org/0000-0002-4023-7542","observed_orcids":["https://orcid.org/0000-0002-4023-7542"]},"institutions":[{"id":"https://openalex.org/I4210152645","display_name":"Fondazione Humanitas per la Ricerca","ror":"https://ror.org/05fa04208","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210152645"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luca Toschi","raw_affiliation_strings":["Medical Oncology Unit, Humanitas Cancer Center, Rozzano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, Humanitas Cancer Center, Rozzano, Italy","institution_ids":["https://openalex.org/I4210152645"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053651576","display_name":"Diego Luigi Cortinovis","orcid":"https://orcid.org/0000-0001-7611-7369","observed_orcids":["https://orcid.org/0000-0001-7611-7369"]},"institutions":[{"id":"https://openalex.org/I4210110840","display_name":"Azienda Ospedaliera San Gerardo","ror":"https://ror.org/01xf83457","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210110840"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Diego Cortinovis","raw_affiliation_strings":["Medical Oncology Unit, ASST Monza, Ospedale San Gerardo, Monza, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Monza, Ospedale San Gerardo, Monza, Italy","institution_ids":["https://openalex.org/I4210110840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109316692","display_name":"Sergio Fava","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4396570473","display_name":"Aziende Socio Sanitarie Territoriale Ovest Milanese","ror":"https://ror.org/027de0q95","country_code":"IT","type":"government","lineage":["https://openalex.org/I4396570473"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sergio Fava","raw_affiliation_strings":["Medical Oncology Unit, ASST Ovest Milanese, Legnano, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Ovest Milanese, Legnano, Milan, Italy","institution_ids":["https://openalex.org/I4396570473"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053244829","display_name":"Virginio Filipazzi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Virginio Filipazzi","raw_affiliation_strings":["Medical Oncology Unit, ASST FBF-Sacco, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST FBF-Sacco, Milan, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067754025","display_name":"Alessandro Tuzi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4396570597","display_name":"Aziende Socio Sanitarie Territoriale dei Sette Laghi","ror":"https://ror.org/00xanm517","country_code":"IT","type":"government","lineage":["https://openalex.org/I4396570597"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Tuzi","raw_affiliation_strings":["Medical Oncology Unit, ASST Settelaghi, Varese, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Settelaghi, Varese, Italy","institution_ids":["https://openalex.org/I4396570597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091886023","display_name":"Giulio Cerea","orcid":"https://orcid.org/0000-0003-1133-0681","observed_orcids":["https://orcid.org/0000-0003-1133-0681"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giulio Cerea","raw_affiliation_strings":["Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy; Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy; Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210094195"]},{"raw_affiliation_string":"Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044102832","display_name":"Sabrina Rossi","orcid":"https://orcid.org/0000-0001-8853-0775","observed_orcids":["https://orcid.org/0000-0001-8853-0775"]},"institutions":[{"id":"https://openalex.org/I4210152645","display_name":"Fondazione Humanitas per la Ricerca","ror":"https://ror.org/05fa04208","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210152645"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sabrina Rossi","raw_affiliation_strings":["Medical Oncology Unit, Humanitas Cancer Center, Rozzano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, Humanitas Cancer Center, Rozzano, Italy","institution_ids":["https://openalex.org/I4210152645"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040983291","display_name":"Vittorio Perfetti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4396570512","display_name":"Azienda Socio Sanitaria Territoriale di Pavia","ror":"https://ror.org/05rjxqp98","country_code":"IT","type":"government","lineage":["https://openalex.org/I4396570512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Vittorio Perfetti","raw_affiliation_strings":["Internal Medicine Unit, Oncologia Oltrep\u00f2, Ospedale di Varzi, ASST Pavia, Pavia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine Unit, Oncologia Oltrep\u00f2, Ospedale di Varzi, ASST Pavia, Pavia, Italy","institution_ids":["https://openalex.org/I4396570512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032078755","display_name":"Ant\u00f4nio Rossi","orcid":"https://orcid.org/0000-0003-3295-0345","observed_orcids":["https://orcid.org/0000-0003-3295-0345"]},"institutions":[{"id":"https://openalex.org/I2800188116","display_name":"Casa Sollievo della Sofferenza","ror":"https://ror.org/00md77g41","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2800188116","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Rossi","raw_affiliation_strings":["Medical Oncology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy","institution_ids":["https://openalex.org/I2800188116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085109152","display_name":"Laura Giuseppina Giannetta","orcid":"https://orcid.org/0009-0006-0943-0017","observed_orcids":["https://orcid.org/0009-0006-0943-0017"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura Giannetta","raw_affiliation_strings":["Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy; Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy; Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210094195"]},{"raw_affiliation_string":"Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033124196","display_name":"Luca Sala","orcid":"https://orcid.org/0000-0003-4568-5739","observed_orcids":["https://orcid.org/0000-0003-4568-5739"]},"institutions":[{"id":"https://openalex.org/I4210110840","display_name":"Azienda Ospedaliera San Gerardo","ror":"https://ror.org/01xf83457","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210110840"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luca Sala","raw_affiliation_strings":["Medical Oncology Unit, ASST Monza, Ospedale San Gerardo, Monza, Italy"],"raw_orcid":"https://orcid.org/0000-0003-4568-5739","affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Monza, Ospedale San Gerardo, Monza, Italy","institution_ids":["https://openalex.org/I4210110840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017416242","display_name":"Giovanna Finocchiaro","orcid":"https://orcid.org/0000-0001-6663-1989","observed_orcids":["https://orcid.org/0000-0001-6663-1989"]},"institutions":[{"id":"https://openalex.org/I4210152645","display_name":"Fondazione Humanitas per la Ricerca","ror":"https://ror.org/05fa04208","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210152645"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanna Finocchiaro","raw_affiliation_strings":["Medical Oncology Unit, Humanitas Cancer Center, Rozzano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, Humanitas Cancer Center, Rozzano, Italy","institution_ids":["https://openalex.org/I4210152645"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031726098","display_name":"Elio Gregory Pizzutilo","orcid":"https://orcid.org/0000-0002-1440-1820","observed_orcids":["https://orcid.org/0000-0002-1440-1820"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elio Gregory Pizzutilo","raw_affiliation_strings":["Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy; Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy"],"raw_orcid":"https://orcid.org/0000-0002-1440-1820","affiliations":[{"raw_affiliation_string":"Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy; Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210094195"]},{"raw_affiliation_string":"Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055981443","display_name":"Stephana Carelli","orcid":"https://orcid.org/0000-0003-4603-396X","observed_orcids":["https://orcid.org/0000-0003-4603-396X"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stephana Carelli","raw_affiliation_strings":["Department of Pharmacology, University of Milan, Milan Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Milan, Milan Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017516824","display_name":"Francesco Agustoni","orcid":"https://orcid.org/0000-0002-4334-1230","observed_orcids":["https://orcid.org/0000-0002-4334-1230"]},"institutions":[{"id":"https://openalex.org/I4210110840","display_name":"Azienda Ospedaliera San Gerardo","ror":"https://ror.org/01xf83457","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210110840"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesco Agustoni","raw_affiliation_strings":["Medical Oncology Unit, ASST Monza, Ospedale San Gerardo, Monza, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Monza, Ospedale San Gerardo, Monza, Italy","institution_ids":["https://openalex.org/I4210110840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068719556","display_name":"Massimiliano Cergnul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4396570473","display_name":"Aziende Socio Sanitarie Territoriale Ovest Milanese","ror":"https://ror.org/027de0q95","country_code":"IT","type":"government","lineage":["https://openalex.org/I4396570473"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimiliano Cergnul","raw_affiliation_strings":["Medical Oncology Unit, ASST Ovest Milanese, Legnano, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Ovest Milanese, Legnano, Milan, Italy","institution_ids":["https://openalex.org/I4396570473"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048844571","display_name":"S. Zonato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4396570669","display_name":"Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo","ror":"https://ror.org/03dpchx26","country_code":"IT","type":"government","lineage":["https://openalex.org/I4396570669"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sabrina Zonato","raw_affiliation_strings":["Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4396570669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031031537","display_name":"Salvatore Siena","orcid":"https://orcid.org/0000-0002-2681-2846","observed_orcids":["https://orcid.org/0000-0002-2681-2846"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Salvatore Siena","raw_affiliation_strings":["Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy; Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy"],"raw_orcid":"https://orcid.org/0000-0002-2681-2846","affiliations":[{"raw_affiliation_string":"Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy; Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4210094195"]},{"raw_affiliation_string":"Dipartimento di Oncologia e Emato-Oncologia, Universit\u00e0 degli Studi di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Medical Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy","institution_ids":["https://openalex.org/I4210094195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089891961","display_name":"Paolo Bidoli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110840","display_name":"Azienda Ospedaliera San Gerardo","ror":"https://ror.org/01xf83457","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210110840"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Bidoli","raw_affiliation_strings":["Medical Oncology Unit, ASST Monza, Ospedale San Gerardo, Monza, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Monza, Ospedale San Gerardo, Monza, Italy","institution_ids":["https://openalex.org/I4210110840"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087209198","display_name":"Daris Ferrari","orcid":"https://orcid.org/0000-0002-1941-7549","observed_orcids":["https://orcid.org/0000-0002-1941-7549"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4396570669","display_name":"Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo","ror":"https://ror.org/03dpchx26","country_code":"IT","type":"government","lineage":["https://openalex.org/I4396570669"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Daris Ferrari","raw_affiliation_strings":["Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Unit, ASST Santi Paolo e Carlo, Universit\u00e0\u0300 di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4396570669"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5009884142"],"corresponding_institution_ids":["https://openalex.org/I189158943","https://openalex.org/I4396570669"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":null,"fwci":2.0804,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.8922126,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"21","issue":"6","first_page":"e567","last_page":"e571"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.9649999737739563},{"id":"https://openalex.org/keywords/pd-1-pd-l1-blockade","display_name":"PD-1/PD-L1 blockade","score":0.9100000262260437},{"id":"https://openalex.org/keywords/immune-checkpoint-inhibitors","display_name":"immune checkpoint inhibitors","score":0.8130000233650208},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.8840000033378601},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.4309999942779541},{"id":"https://openalex.org/keywords/immunotherapy-efficacy","display_name":"immunotherapy efficacy","score":0.6539999842643738},{"id":"https://openalex.org/keywords/immunotherapy-safety","display_name":"immunotherapy safety","score":0.8769999742507935},{"id":"https://openalex.org/keywords/immune-related-adverse-events","display_name":"immune-related adverse events","score":0.9980000257492065},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.921999990940094},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9990000128746033},{"id":"https://openalex.org/keywords/smoking-status","display_name":"smoking status","score":0.8389999866485596},{"id":"https://openalex.org/keywords/real-world-outcomes","display_name":"real-world outcomes","score":0.6690000295639038},{"id":"https://openalex.org/keywords/metastatic-nsclc","display_name":"metastatic non-small cell lung cancer","score":0.7770000100135803},{"id":"https://openalex.org/keywords/age-as-prognostic-factor","display_name":"age as prognostic factor","score":0.5720000267028809}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9338160157203674},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7142449617385864},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.7103248238563538},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5961859226226807},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.4850236773490906},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4777064323425293},{"id":"https://openalex.org/C117643217","wikidata":"https://www.wikidata.org/wiki/Q17824987","display_name":"Anaplastic lymphoma kinase","level":4,"score":0.4770062267780304},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.46011263132095337},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.429962694644928},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C2776232967","wikidata":"https://www.wikidata.org/wiki/Q6743514","display_name":"Malignant pleural effusion","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000074322","descriptor_name":"Antineoplastic Agents, Immunological","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000077192","descriptor_name":"Adenocarcinoma of Lung","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000077192","descriptor_name":"Adenocarcinoma of Lung","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000077192","descriptor_name":"Adenocarcinoma of Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060890","descriptor_name":"B7-H1 Antigen","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.cllc.2020.05.004","doi":"https://doi.org/10.1016/j.cllc.2020.05.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cllc.2020.05.004","pdf_url":null,"source":{"id":"https://openalex.org/S32518486","display_name":"Clinical Lung Cancer","issn_l":"1525-7304","issn":["1525-7304","1938-0690"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Lung Cancer","raw_type":"journal-article"},{"id":"pmid:32591311","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32591311","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical lung cancer","raw_type":"Journal Article"},{"id":"pmh:oai:boa.unimib.it:10281/302900","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10281/302900","pdf_url":null,"source":{"id":"https://openalex.org/S4306401259","display_name":"BOA (University of Milano-Bicocca)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320313475","display_name":"Universit\u00e0 degli Studi di Milano","ror":"https://ror.org/00wjc7c48"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W2104347254","https://openalex.org/W2109809243","https://openalex.org/W2121095198","https://openalex.org/W2156353875","https://openalex.org/W2163351155","https://openalex.org/W2163787988","https://openalex.org/W2177405394","https://openalex.org/W2198093519","https://openalex.org/W2293531514","https://openalex.org/W2527905628","https://openalex.org/W2567564314","https://openalex.org/W2571477718","https://openalex.org/W2753207486","https://openalex.org/W2759297801","https://openalex.org/W2767217686","https://openalex.org/W2784243589","https://openalex.org/W2784371446","https://openalex.org/W2786816161","https://openalex.org/W2790743957","https://openalex.org/W2791290180","https://openalex.org/W2883381386","https://openalex.org/W2889646458","https://openalex.org/W2910245285","https://openalex.org/W2925446385","https://openalex.org/W2939507240","https://openalex.org/W2939645052","https://openalex.org/W2988002600","https://openalex.org/W6744452582","https://openalex.org/W6761592365"],"related_works":["https://openalex.org/W2895908834","https://openalex.org/W4210625632","https://openalex.org/W2790782691","https://openalex.org/W4396722240","https://openalex.org/W2892242245","https://openalex.org/W3136100433","https://openalex.org/W4399757996","https://openalex.org/W2972829090","https://openalex.org/W3128439679","https://openalex.org/W2981699551"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-05-21T00:00:00"}