{"id":"https://openalex.org/W3024149019","doi":"https://doi.org/10.1038/s41577-020-0307-4","title":"Clonal expansion of innate and adaptive lymphocytes","display_name":"Clonal expansion of innate and adaptive lymphocytes","publication_year":2020,"publication_date":"2020-05-18","ids":{"openalex":"https://openalex.org/W3024149019","doi":"https://doi.org/10.1038/s41577-020-0307-4","mag":"3024149019","pmid":"https://pubmed.ncbi.nlm.nih.gov/32424244","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13119617"},"language":"en","primary_location":{"id":"doi:10.1038/s41577-020-0307-4","doi":"https://doi.org/10.1038/s41577-020-0307-4","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41577-020-0307-4","pdf_url":null,"source":{"id":"https://openalex.org/S93373720","display_name":"Nature reviews. Immunology","issn_l":"1474-1733","issn":["1474-1733","1474-1741"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Immunology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13119617/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027806169","display_name":"Nicholas M. Adams","orcid":"https://orcid.org/0000-0001-5751-0480","observed_orcids":["https://orcid.org/0000-0001-5751-0480"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicholas M. Adams","raw_affiliation_strings":["Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011196280","display_name":"Simon A. Grassmann","orcid":"https://orcid.org/0000-0002-8336-3418","observed_orcids":["https://orcid.org/0000-0002-8336-3418"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Simon Grassmann","raw_affiliation_strings":["Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065491591","display_name":"Joseph Chai-Yuen Sun","orcid":"https://orcid.org/0000-0001-8062-9033","observed_orcids":["https://orcid.org/0000-0001-8062-9033"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joseph C. Sun","raw_affiliation_strings":["Department of Immunology and Microbial Pathogenesis, Weill Cornell Medical College, New York, NY, USA. sunj@mskcc.org","Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. sunj@mskcc.org","Department of Immunology and Microbial Pathogenesis, Weill Cornell Medical College, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-8062-9033","affiliations":[{"raw_affiliation_string":"Department of Immunology and Microbial Pathogenesis, Weill Cornell Medical College, New York, NY, USA. sunj@mskcc.org","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. sunj@mskcc.org","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Immunology and Microbial Pathogenesis, Weill Cornell Medical College, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5065491591"],"corresponding_institution_ids":["https://openalex.org/I1334819555","https://openalex.org/I4387153466"],"apc_list":null,"apc_paid":null,"fwci":1.611,"has_fulltext":false,"cited_by_count":129,"citation_normalized_percentile":{"value":0.85952534,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"20","issue":"11","first_page":"694","last_page":"707"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12528","display_name":"IL-33, ST2, and ILC Pathways","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clonal-expansion","display_name":"clonal expansion","score":1.0},{"id":"https://openalex.org/keywords/innate-lymphoid-cells","display_name":"innate lymphoid cells","score":0.984000027179718},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.8730000257492065},{"id":"https://openalex.org/keywords/cytomegalovirus-infection","display_name":"cytomegalovirus infection","score":0.8859999775886536},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.972000002861023},{"id":"https://openalex.org/keywords/adaptive-immune-response","display_name":"adaptive immune response","score":0.5950000286102295},{"id":"https://openalex.org/keywords/lymphocyte-heterogeneity","display_name":"lymphocyte heterogeneity","score":0.7760000228881836},{"id":"https://openalex.org/keywords/lymphocyte-differentiation","display_name":"lymphocyte differentiation","score":0.6840000152587891},{"id":"https://openalex.org/keywords/pathogen-challenge","display_name":"pathogen challenge","score":0.5370000004768372}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.783979058265686},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.7242398858070374},{"id":"https://openalex.org/C47742525","wikidata":"https://www.wikidata.org/wiki/Q13418826","display_name":"Innate lymphoid cell","level":4,"score":0.6724140048027039},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5867397785186768},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5856529474258423},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.5560014843940735},{"id":"https://openalex.org/C2776954793","wikidata":"https://www.wikidata.org/wiki/Q1150780","display_name":"Clonal selection","level":2,"score":0.43201613426208496},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.41574668884277344},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002999","descriptor_name":"Clone Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007156","descriptor_name":"Immunologic Memory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D056704","descriptor_name":"Adaptive Immunity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1038/s41577-020-0307-4","doi":"https://doi.org/10.1038/s41577-020-0307-4","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41577-020-0307-4","pdf_url":null,"source":{"id":"https://openalex.org/S93373720","display_name":"Nature reviews. Immunology","issn_l":"1474-1733","issn":["1474-1733","1474-1741"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Immunology","raw_type":"journal-article"},{"id":"pmid:32424244","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32424244","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature reviews. Immunology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13119617","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13119617/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Rev Immunol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:13119617","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13119617/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Rev Immunol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Zero hunger","score":0.6299999952316284,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4547564537","display_name":"Regulation of Nfil3 in innate lymphocyte-mediated host immunity","funder_award_id":"R01AI130043","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000856728","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000886845","display_name":"The natural killer cell response against mouse cytomegalovirus infection","funder_award_id":"R01AI100874","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":203,"referenced_works":["https://openalex.org/W29164706","https://openalex.org/W1482928030","https://openalex.org/W1483372876","https://openalex.org/W1487003048","https://openalex.org/W1489480103","https://openalex.org/W1491399868","https://openalex.org/W1507800008","https://openalex.org/W1515587936","https://openalex.org/W1517571699","https://openalex.org/W1522207028","https://openalex.org/W1541097619","https://openalex.org/W1541571439","https://openalex.org/W1547859938","https://openalex.org/W1568710114","https://openalex.org/W1580179014","https://openalex.org/W1584891848","https://openalex.org/W1603412780","https://openalex.org/W1786216877","https://openalex.org/W1830427486","https://openalex.org/W1846859917","https://openalex.org/W1873760231","https://openalex.org/W1878895776","https://openalex.org/W1910209415","https://openalex.org/W1936525329","https://openalex.org/W1944461161","https://openalex.org/W1964081728","https://openalex.org/W1966280572","https://openalex.org/W1966315835","https://openalex.org/W1967867591","https://openalex.org/W1970591872","https://openalex.org/W1972452655","https://openalex.org/W1974842026","https://openalex.org/W1975717760","https://openalex.org/W1976062745","https://openalex.org/W1976785514","https://openalex.org/W1982084822","https://openalex.org/W1985259673","https://openalex.org/W1985294654","https://openalex.org/W1989712520","https://openalex.org/W1990555844","https://openalex.org/W1992267675","https://openalex.org/W1993695522","https://openalex.org/W1994500716","https://openalex.org/W1996483176","https://openalex.org/W1996699270","https://openalex.org/W1997508510","https://openalex.org/W1997849135","https://openalex.org/W1998856404","https://openalex.org/W1999092913","https://openalex.org/W2002541767","https://openalex.org/W2002718676","https://openalex.org/W2003016286","https://openalex.org/W2003803349","https://openalex.org/W2004663864","https://openalex.org/W2004729573","https://openalex.org/W2005091069","https://openalex.org/W2006645462","https://openalex.org/W2009655220","https://openalex.org/W2010436799","https://openalex.org/W2013249454","https://openalex.org/W2014097269","https://openalex.org/W2014954180","https://openalex.org/W2016208474","https://openalex.org/W2021028235","https://openalex.org/W2021936785","https://openalex.org/W2024183493","https://openalex.org/W2027132663","https://openalex.org/W2029229136","https://openalex.org/W2031011895","https://openalex.org/W2033289727","https://openalex.org/W2039045791","https://openalex.org/W2039638023","https://openalex.org/W2040080235","https://openalex.org/W2041413771","https://openalex.org/W2041658172","https://openalex.org/W2042519375","https://openalex.org/W2043570079","https://openalex.org/W2043793366","https://openalex.org/W2047742947","https://openalex.org/W2048245039","https://openalex.org/W2051103323","https://openalex.org/W2051890542","https://openalex.org/W2057459783","https://openalex.org/W2058634008","https://openalex.org/W2059431619","https://openalex.org/W2060334409","https://openalex.org/W2060530677","https://openalex.org/W2060798773","https://openalex.org/W2061079054","https://openalex.org/W2061187116","https://openalex.org/W2061630978","https://openalex.org/W2061728907","https://openalex.org/W2064008537","https://openalex.org/W2066011015","https://openalex.org/W2066887263","https://openalex.org/W2068290887","https://openalex.org/W2069007188","https://openalex.org/W2070716243","https://openalex.org/W2072158757","https://openalex.org/W2072819208","https://openalex.org/W2085140645","https://openalex.org/W2085826293","https://openalex.org/W2085887337","https://openalex.org/W2086221877","https://openalex.org/W2086559838","https://openalex.org/W2091218020","https://openalex.org/W2095548329","https://openalex.org/W2095738250","https://openalex.org/W2096449627","https://openalex.org/W2096879752","https://openalex.org/W2100778289","https://openalex.org/W2102264469","https://openalex.org/W2102810679","https://openalex.org/W2102950218","https://openalex.org/W2105381977","https://openalex.org/W2105656877","https://openalex.org/W2106166533","https://openalex.org/W2108629998","https://openalex.org/W2108909957","https://openalex.org/W2110988104","https://openalex.org/W2112278838","https://openalex.org/W2112562079","https://openalex.org/W2114569569","https://openalex.org/W2114866609","https://openalex.org/W2118613671","https://openalex.org/W2119532085","https://openalex.org/W2120811539","https://openalex.org/W2123891071","https://openalex.org/W2124532544","https://openalex.org/W2125024220","https://openalex.org/W2126168881","https://openalex.org/W2131189233","https://openalex.org/W2133567701","https://openalex.org/W2135657057","https://openalex.org/W2136555855","https://openalex.org/W2138073407","https://openalex.org/W2139538130","https://openalex.org/W2139612810","https://openalex.org/W2141205048","https://openalex.org/W2141352299","https://openalex.org/W2141863692","https://openalex.org/W2142269459","https://openalex.org/W2144890743","https://openalex.org/W2145026575","https://openalex.org/W2145149316","https://openalex.org/W2145786937","https://openalex.org/W2146261880","https://openalex.org/W2148238340","https://openalex.org/W2148817537","https://openalex.org/W2150098469","https://openalex.org/W2150433660","https://openalex.org/W2150992850","https://openalex.org/W2154154640","https://openalex.org/W2155344565","https://openalex.org/W2162377851","https://openalex.org/W2165144791","https://openalex.org/W2165232639","https://openalex.org/W2166807496","https://openalex.org/W2171018382","https://openalex.org/W2171709048","https://openalex.org/W2238877049","https://openalex.org/W2384384918","https://openalex.org/W2417976637","https://openalex.org/W2443873000","https://openalex.org/W2468936205","https://openalex.org/W2470787644","https://openalex.org/W2481706030","https://openalex.org/W2521461373","https://openalex.org/W2531140561","https://openalex.org/W2531442545","https://openalex.org/W2533998772","https://openalex.org/W2552726189","https://openalex.org/W2557929645","https://openalex.org/W2601006710","https://openalex.org/W2605350170","https://openalex.org/W2739015332","https://openalex.org/W2739505325","https://openalex.org/W2748393371","https://openalex.org/W2755626561","https://openalex.org/W2774214122","https://openalex.org/W2775411941","https://openalex.org/W2786332713","https://openalex.org/W2796260135","https://openalex.org/W2796894443","https://openalex.org/W2801693695","https://openalex.org/W2806582733","https://openalex.org/W2808386207","https://openalex.org/W2884312175","https://openalex.org/W2887976969","https://openalex.org/W2888645341","https://openalex.org/W2890056446","https://openalex.org/W2898675725","https://openalex.org/W2899566169","https://openalex.org/W2902856530","https://openalex.org/W2938210236","https://openalex.org/W2938819364","https://openalex.org/W2945239922","https://openalex.org/W2946574824","https://openalex.org/W2953946606","https://openalex.org/W2960238068","https://openalex.org/W3004611567","https://openalex.org/W4242765117","https://openalex.org/W6636465723"],"related_works":["https://openalex.org/W4393002677","https://openalex.org/W1982084822","https://openalex.org/W7098399633","https://openalex.org/W1578253113","https://openalex.org/W4386554337","https://openalex.org/W3159606085","https://openalex.org/W2797635549","https://openalex.org/W3088486443","https://openalex.org/W2946574824","https://openalex.org/W4247108954"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":22},{"year":2024,"cited_by_count":21},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":26},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-05-21T00:00:00"}