{"id":"https://openalex.org/W3023906975","doi":"https://doi.org/10.1038/s41575-020-0300-1","title":"Pancreatic cancer stroma: an update on therapeutic targeting strategies","display_name":"Pancreatic cancer stroma: an update on therapeutic targeting strategies","publication_year":2020,"publication_date":"2020-05-11","ids":{"openalex":"https://openalex.org/W3023906975","doi":"https://doi.org/10.1038/s41575-020-0300-1","mag":"3023906975","pmid":"https://pubmed.ncbi.nlm.nih.gov/32393771","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8284850"},"language":"en","primary_location":{"id":"doi:10.1038/s41575-020-0300-1","doi":"https://doi.org/10.1038/s41575-020-0300-1","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41575-020-0300-1","pdf_url":null,"source":{"id":"https://openalex.org/S120397320","display_name":"Nature Reviews Gastroenterology & Hepatology","issn_l":"1759-5045","issn":["1759-5045","1759-5053"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Gastroenterology & Hepatology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8284850","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068240507","display_name":"Abdel Nasser Hosein","orcid":"https://orcid.org/0000-0003-1567-6700","observed_orcids":["https://orcid.org/0000-0003-1567-6700"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abdel N. Hosein","raw_affiliation_strings":["Department of Internal Medicine, Division of Hematology & Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA","Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA","Sheikh Ahmed Center for Pancreatic Cancer Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Division of Hematology & Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Sheikh Ahmed Center for Pancreatic Cancer Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089104361","display_name":"Rolf A. Brekken","orcid":"https://orcid.org/0000-0003-2704-2377","observed_orcids":["https://orcid.org/0000-0003-2704-2377"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rolf A. Brekken","raw_affiliation_strings":["Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA. rolf.brekken@utsouthwestern.edu","Hamon Center for Therapeutic Oncology Research and Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA. rolf.brekken@utsouthwestern.edu","Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA"],"raw_orcid":"https://orcid.org/0000-0003-2704-2377","affiliations":[{"raw_affiliation_string":"Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA. rolf.brekken@utsouthwestern.edu","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"Hamon Center for Therapeutic Oncology Research and Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA. rolf.brekken@utsouthwestern.edu","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048073439","display_name":"Anirban Maitra","orcid":"https://orcid.org/0000-0001-7923-9978","observed_orcids":["https://orcid.org/0000-0001-7923-9978","https://orcid.org/0000-0003-0298-9775"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Anirban Maitra","raw_affiliation_strings":["Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. amaitra@mdanderson.org","Sheikh Ahmed Center for Pancreatic Cancer Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA. amaitra@mdanderson.org","Sheikh Ahmed Center for Pancreatic Cancer Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA"],"raw_orcid":"https://orcid.org/0000-0001-7923-9978","affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. amaitra@mdanderson.org","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Sheikh Ahmed Center for Pancreatic Cancer Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA. amaitra@mdanderson.org","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Sheikh Ahmed Center for Pancreatic Cancer Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5048073439","https://openalex.org/A5089104361"],"corresponding_institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I867280407"],"apc_list":null,"apc_paid":null,"fwci":13.2415,"has_fulltext":false,"cited_by_count":968,"citation_normalized_percentile":{"value":0.99403895,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"17","issue":"8","first_page":"487","last_page":"505"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-ductal-adenocarcinoma","display_name":"pancreatic ductal adenocarcinoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tumor-stroma","display_name":"tumor stroma","score":0.8550000190734863},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.9649999737739563},{"id":"https://openalex.org/keywords/tumor-vasculature","display_name":"tumor vasculature","score":0.8830000162124634},{"id":"https://openalex.org/keywords/cancer-associated-fibroblasts","display_name":"cancer-associated fibroblasts","score":0.949999988079071},{"id":"https://openalex.org/keywords/anti-angiogenic-therapy","display_name":"anti-angiogenic therapy","score":0.6639999747276306},{"id":"https://openalex.org/keywords/vessel-normalization","display_name":"vessel normalization","score":0.9509999752044678},{"id":"https://openalex.org/keywords/tumor-immune-microenvironment","display_name":"tumor immune microenvironment","score":0.8730000257492065},{"id":"https://openalex.org/keywords/drug-delivery-barriers","display_name":"drug delivery barriers","score":0.6079999804496765},{"id":"https://openalex.org/keywords/caf-heterogeneity","display_name":"CAF heterogeneity","score":0.8659999966621399},{"id":"https://openalex.org/keywords/myofibroblastic-cafs","display_name":"myofibroblastic CAFs","score":0.9010000228881836},{"id":"https://openalex.org/keywords/inflammatory-cafs","display_name":"inflammatory CAFs","score":0.8939999938011169},{"id":"https://openalex.org/keywords/therapeutic-targeting","display_name":"therapeutic targeting","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C52124034","wikidata":"https://www.wikidata.org/wiki/Q557179","display_name":"Stroma","level":3,"score":0.858291506767273},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.716204822063446},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.6830698251724243},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6245967745780945},{"id":"https://openalex.org/C2909706936","wikidata":"https://www.wikidata.org/wiki/Q42417562","display_name":"Cancer-Associated Fibroblasts","level":4,"score":0.6181883811950684},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.575961172580719},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.554867148399353},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5535547733306885},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5036618113517761},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.49081191420555115},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4815678596496582},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4556870460510254},{"id":"https://openalex.org/C2781005279","wikidata":"https://www.wikidata.org/wiki/Q5264825","display_name":"Desmoplasia","level":4,"score":0.42677509784698486},{"id":"https://openalex.org/C2779256057","wikidata":"https://www.wikidata.org/wiki/Q16909647","display_name":"Tumor progression","level":3,"score":0.42526674270629883},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37213391065597534},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3122778534889221},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15186962485313416},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.11652103066444397},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.11129361391067505}],"mesh":[{"descriptor_ui":"D000072645","descriptor_name":"Cancer-Associated Fibroblasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001549","descriptor_name":"Benzamides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006820","descriptor_name":"Hyaluronic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006821","descriptor_name":"Hyaluronoglucosaminidase","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010539","descriptor_name":"Permeability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011719","descriptor_name":"Pyrazines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013449","descriptor_name":"Sulfonamides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019307","descriptor_name":"1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D019307","descriptor_name":"1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D020533","descriptor_name":"Angiogenesis Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D021441","descriptor_name":"Carcinoma, Pancreatic Ductal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D021441","descriptor_name":"Carcinoma, Pancreatic Ductal","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D021441","descriptor_name":"Carcinoma, Pancreatic Ductal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D021441","descriptor_name":"Carcinoma, Pancreatic Ductal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045604","descriptor_name":"Extracellular Fluid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047428","descriptor_name":"Protein Kinase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051416","descriptor_name":"Focal Adhesion Protein-Tyrosine Kinases","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D054460","descriptor_name":"rho-Associated Kinases","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D058990","descriptor_name":"Molecular Targeted Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1038/s41575-020-0300-1","doi":"https://doi.org/10.1038/s41575-020-0300-1","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41575-020-0300-1","pdf_url":null,"source":{"id":"https://openalex.org/S120397320","display_name":"Nature Reviews Gastroenterology & Hepatology","issn_l":"1759-5045","issn":["1759-5045","1759-5053"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Gastroenterology & Hepatology","raw_type":"journal-article"},{"id":"pmid:32393771","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32393771","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature reviews. Gastroenterology & hepatology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8284850","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8284850","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Rev Gastroenterol Hepatol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8284850","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8284850","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Rev Gastroenterol Hepatol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2258116482","display_name":"Center for Immunotherapeutic Transport Oncophysics","funder_award_id":"U54CA210181","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5260150436","display_name":"Wnt/?-catenin Signaling in Pancreatic Oncogenesis","funder_award_id":"R01CA220236","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5427789088","display_name":"Digital Nanoplasmonic Quantification of Tumor-derived Extracellular Vesicles in Plasma Microsamples","funder_award_id":"U01CA252965","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7074898331","display_name":"Pancreatic Ductal Adenocarcinoma Translational Resource Center (PATReC)","funder_award_id":"U24CA224020","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7383019357","display_name":"Exploitation of RAS signaling to develop therapy and early detection strategies for PDA","funder_award_id":"R01CA192381","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8790808168","display_name":"Translational Applications in an Animal Model of Pancreatic Cystic Neoplasm and Cancer","funder_award_id":"R01CA218004","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":192,"referenced_works":["https://openalex.org/W5139590","https://openalex.org/W124503910","https://openalex.org/W176315691","https://openalex.org/W1488828742","https://openalex.org/W1497915798","https://openalex.org/W1539571840","https://openalex.org/W1552867725","https://openalex.org/W1603230122","https://openalex.org/W1616217811","https://openalex.org/W1820142295","https://openalex.org/W1846628434","https://openalex.org/W1858549592","https://openalex.org/W1940241680","https://openalex.org/W1965498876","https://openalex.org/W1965691956","https://openalex.org/W1967600348","https://openalex.org/W1971298987","https://openalex.org/W1973147485","https://openalex.org/W1976156924","https://openalex.org/W1977439064","https://openalex.org/W1978139448","https://openalex.org/W1978148663","https://openalex.org/W1978598058","https://openalex.org/W1979704965","https://openalex.org/W1985780641","https://openalex.org/W1986689328","https://openalex.org/W1996912024","https://openalex.org/W2005082047","https://openalex.org/W2006202974","https://openalex.org/W2013093033","https://openalex.org/W2022334439","https://openalex.org/W2031960993","https://openalex.org/W2033116719","https://openalex.org/W2033878276","https://openalex.org/W2044905529","https://openalex.org/W2050987511","https://openalex.org/W2052112616","https://openalex.org/W2052783034","https://openalex.org/W2053056834","https://openalex.org/W2054302145","https://openalex.org/W2054633892","https://openalex.org/W2054728198","https://openalex.org/W2055091294","https://openalex.org/W2056761337","https://openalex.org/W2059253566","https://openalex.org/W2071969437","https://openalex.org/W2073464835","https://openalex.org/W2076458597","https://openalex.org/W2080202443","https://openalex.org/W2080311095","https://openalex.org/W2081143051","https://openalex.org/W2086834665","https://openalex.org/W2088110734","https://openalex.org/W2088571368","https://openalex.org/W2088812649","https://openalex.org/W2092564256","https://openalex.org/W2094748245","https://openalex.org/W2097926059","https://openalex.org/W2098054841","https://openalex.org/W2099170646","https://openalex.org/W2101025132","https://openalex.org/W2101037339","https://openalex.org/W2104416279","https://openalex.org/W2106932520","https://openalex.org/W2107932305","https://openalex.org/W2110957241","https://openalex.org/W2115852392","https://openalex.org/W2115898240","https://openalex.org/W2118362228","https://openalex.org/W2123769936","https://openalex.org/W2124863710","https://openalex.org/W2128095147","https://openalex.org/W2128565827","https://openalex.org/W2129176863","https://openalex.org/W2129338773","https://openalex.org/W2130464657","https://openalex.org/W2132635696","https://openalex.org/W2137217704","https://openalex.org/W2137357003","https://openalex.org/W2137508065","https://openalex.org/W2140088548","https://openalex.org/W2140741923","https://openalex.org/W2140765540","https://openalex.org/W2140814324","https://openalex.org/W2141815918","https://openalex.org/W2143866789","https://openalex.org/W2146905485","https://openalex.org/W2147000598","https://openalex.org/W2149449623","https://openalex.org/W2151253787","https://openalex.org/W2152143404","https://openalex.org/W2152999504","https://openalex.org/W2154670252","https://openalex.org/W2154790710","https://openalex.org/W2157923000","https://openalex.org/W2159603425","https://openalex.org/W2159986837","https://openalex.org/W2165036434","https://openalex.org/W2165480504","https://openalex.org/W2168467781","https://openalex.org/W2169281418","https://openalex.org/W2170189698","https://openalex.org/W2236482561","https://openalex.org/W2257916031","https://openalex.org/W2285093314","https://openalex.org/W2336612200","https://openalex.org/W2337683177","https://openalex.org/W2341205093","https://openalex.org/W2376800108","https://openalex.org/W2397703541","https://openalex.org/W2410550525","https://openalex.org/W2416037803","https://openalex.org/W2417750143","https://openalex.org/W2461243283","https://openalex.org/W2469223980","https://openalex.org/W2510391033","https://openalex.org/W2512899508","https://openalex.org/W2514792180","https://openalex.org/W2515281308","https://openalex.org/W2518979191","https://openalex.org/W2530909341","https://openalex.org/W2537220355","https://openalex.org/W2539381937","https://openalex.org/W2551414968","https://openalex.org/W2553667461","https://openalex.org/W2564262333","https://openalex.org/W2564508307","https://openalex.org/W2574819148","https://openalex.org/W2585474788","https://openalex.org/W2590390825","https://openalex.org/W2600825713","https://openalex.org/W2601414401","https://openalex.org/W2605955768","https://openalex.org/W2607031175","https://openalex.org/W2617028083","https://openalex.org/W2622499649","https://openalex.org/W2624910490","https://openalex.org/W2726164542","https://openalex.org/W2727977279","https://openalex.org/W2739958559","https://openalex.org/W2746888048","https://openalex.org/W2748710555","https://openalex.org/W2751614779","https://openalex.org/W2753114438","https://openalex.org/W2768772819","https://openalex.org/W2769127580","https://openalex.org/W2781548451","https://openalex.org/W2783122422","https://openalex.org/W2783528540","https://openalex.org/W2790254562","https://openalex.org/W2790313758","https://openalex.org/W2791166453","https://openalex.org/W2791757202","https://openalex.org/W2792595617","https://openalex.org/W2794353934","https://openalex.org/W2798728508","https://openalex.org/W2800458259","https://openalex.org/W2801077576","https://openalex.org/W2804259007","https://openalex.org/W2807088563","https://openalex.org/W2807122763","https://openalex.org/W2808423871","https://openalex.org/W2884689669","https://openalex.org/W2887205254","https://openalex.org/W2889433609","https://openalex.org/W2889646458","https://openalex.org/W2897465705","https://openalex.org/W2898305673","https://openalex.org/W2898435366","https://openalex.org/W2903623792","https://openalex.org/W2917550064","https://openalex.org/W2919508314","https://openalex.org/W2920706987","https://openalex.org/W2936366750","https://openalex.org/W2939684277","https://openalex.org/W2947548345","https://openalex.org/W2947826965","https://openalex.org/W2947955936","https://openalex.org/W2951222857","https://openalex.org/W2964097765","https://openalex.org/W2979127725","https://openalex.org/W2980314475","https://openalex.org/W2986162201","https://openalex.org/W2995820350","https://openalex.org/W3005376508","https://openalex.org/W3134530972","https://openalex.org/W4231968797","https://openalex.org/W4239692346","https://openalex.org/W4247785462","https://openalex.org/W4250877149","https://openalex.org/W4406056548","https://openalex.org/W6885117878"],"related_works":["https://openalex.org/W4313231809","https://openalex.org/W4394618996","https://openalex.org/W7130957072","https://openalex.org/W3196711553","https://openalex.org/W3166338252","https://openalex.org/W3046464662","https://openalex.org/W7212174548","https://openalex.org/W2889990912","https://openalex.org/W4414458130","https://openalex.org/W4295065572"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":153},{"year":2025,"cited_by_count":187},{"year":2024,"cited_by_count":179},{"year":2023,"cited_by_count":152},{"year":2022,"cited_by_count":163},{"year":2021,"cited_by_count":120},{"year":2020,"cited_by_count":14}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-05-13T00:00:00"}