{"id":"https://openalex.org/W3022979367","doi":"https://doi.org/10.3390/ph13050083","title":"Polymyxin Delivery Systems: Recent Advances and Challenges","display_name":"Polymyxin Delivery Systems: Recent Advances and Challenges","publication_year":2020,"publication_date":"2020-04-29","ids":{"openalex":"https://openalex.org/W3022979367","doi":"https://doi.org/10.3390/ph13050083","mag":"3022979367","pmid":"https://pubmed.ncbi.nlm.nih.gov/32365637","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7281078"},"language":"en","primary_location":{"id":"doi:10.3390/ph13050083","doi":"https://doi.org/10.3390/ph13050083","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/ph13050083","pdf_url":"https://www.mdpi.com/1424-8247/13/5/83/pdf?version=1588165155","source":{"id":"https://openalex.org/S16322639","display_name":"Pharmaceuticals","issn_l":"1424-8247","issn":["1424-8247"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8247/13/5/83/pdf?version=1588165155","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084413044","display_name":"Natallia V. Dubashynskaya","orcid":"https://orcid.org/0000-0002-4399-9374","observed_orcids":["https://orcid.org/0000-0002-4399-9374"]},"institutions":[{"id":"https://openalex.org/I4210091702","display_name":"Institute of Macromolecular Compounds","ror":"https://ror.org/00hgmwb30","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210091702","https://openalex.org/I4210145551"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Natallia V. Dubashynskaya","raw_affiliation_strings":["Institute of Macromolecular Compounds of the Russian Academy of Sciences, Bolshoy pr. V.O. 31, St. Petersburg 199004, Russia"],"raw_orcid":"https://orcid.org/0000-0002-4399-9374","affiliations":[{"raw_affiliation_string":"Institute of Macromolecular Compounds of the Russian Academy of Sciences, Bolshoy pr. V.O. 31, St. Petersburg 199004, Russia","institution_ids":["https://openalex.org/I4210091702"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002802866","display_name":"Yury \u0410. Skorik","orcid":"https://orcid.org/0000-0002-9731-6399","observed_orcids":["https://orcid.org/0000-0002-9731-6399"]},"institutions":[{"id":"https://openalex.org/I4210091702","display_name":"Institute of Macromolecular Compounds","ror":"https://ror.org/00hgmwb30","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210091702","https://openalex.org/I4210145551"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Yury A. Skorik","raw_affiliation_strings":["Institute of Macromolecular Compounds of the Russian Academy of Sciences, Bolshoy pr. V.O. 31, St. Petersburg 199004, Russia"],"raw_orcid":"https://orcid.org/0000-0002-9731-6399","affiliations":[{"raw_affiliation_string":"Institute of Macromolecular Compounds of the Russian Academy of Sciences, Bolshoy pr. V.O. 31, St. Petersburg 199004, Russia","institution_ids":["https://openalex.org/I4210091702"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5002802866"],"corresponding_institution_ids":["https://openalex.org/I4210091702"],"apc_list":{"value":1400,"currency":"CHF","value_usd":1479},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1479},"fwci":0.9462,"has_fulltext":true,"cited_by_count":89,"citation_normalized_percentile":{"value":0.66368515,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"13","issue":"5","first_page":"83","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.6977999806404114,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.6977999806404114,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.20080000162124634,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.024399999529123306,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polymyxins","display_name":"polymyxins","score":0.9449999928474426},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.9160000085830688},{"id":"https://openalex.org/keywords/bioavailability","display_name":"bioavailability","score":0.6179999709129333},{"id":"https://openalex.org/keywords/nephrotoxicity","display_name":"nephrotoxicity","score":0.8799999952316284},{"id":"https://openalex.org/keywords/neurotoxicity","display_name":"neurotoxicity","score":0.9950000047683716},{"id":"https://openalex.org/keywords/eskape-pathogens","display_name":"ESKAPE pathogens","score":0.8299999833106995},{"id":"https://openalex.org/keywords/gram-negative-infections","display_name":"gram-negative bacterial infection","score":0.8090000152587891},{"id":"https://openalex.org/keywords/targeted-drug-delivery","display_name":"targeted drug delivery","score":0.5630000233650208},{"id":"https://openalex.org/keywords/controlled-release","display_name":"controlled release","score":0.9750000238418579},{"id":"https://openalex.org/keywords/liposomes","display_name":"liposomes","score":0.7509999871253967},{"id":"https://openalex.org/keywords/polymeric-particles","display_name":"polymer particles","score":0.878000020980835},{"id":"https://openalex.org/keywords/conjugates","display_name":"conjugates","score":0.7480000257492065},{"id":"https://openalex.org/keywords/topical-gel","display_name":"topical gel","score":0.7580000162124634}],"concepts":[{"id":"https://openalex.org/C2780675486","wikidata":"https://www.wikidata.org/wiki/Q423765","display_name":"Polymyxin","level":3,"score":0.9145835638046265},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5653420686721802},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.5514444708824158},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5460678339004517},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5338327288627625},{"id":"https://openalex.org/C2780026444","wikidata":"https://www.wikidata.org/wiki/Q1088175","display_name":"Polymyxin B","level":3,"score":0.5301376581192017},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.4664193093776703},{"id":"https://openalex.org/C185154212","wikidata":"https://www.wikidata.org/wiki/Q410454","display_name":"Liposome","level":2,"score":0.45716843008995056},{"id":"https://openalex.org/C126189478","wikidata":"https://www.wikidata.org/wiki/Q1468324","display_name":"Nephrotoxicity","level":3,"score":0.4544660151004791},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.4520355463027954},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.34938251972198486},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.20523646473884583},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.20395082235336304},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09587901830673218},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/ph13050083","doi":"https://doi.org/10.3390/ph13050083","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/ph13050083","pdf_url":"https://www.mdpi.com/1424-8247/13/5/83/pdf?version=1588165155","source":{"id":"https://openalex.org/S16322639","display_name":"Pharmaceuticals","issn_l":"1424-8247","issn":["1424-8247"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals","raw_type":"journal-article"},{"id":"pmid:32365637","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32365637","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7281078","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7281078/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:4cec63aded6843728b1add621107529d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/4cec63aded6843728b1add621107529d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceuticals, Vol 13, Iss 5, p 83 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/ph13050083","doi":"https://doi.org/10.3390/ph13050083","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/ph13050083","pdf_url":"https://www.mdpi.com/1424-8247/13/5/83/pdf?version=1588165155","source":{"id":"https://openalex.org/S16322639","display_name":"Pharmaceuticals","issn_l":"1424-8247","issn":["1424-8247"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1103711585","display_name":null,"funder_award_id":"19-73-20157","funder_id":"https://openalex.org/F4320324099","funder_display_name":"Russian Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320324099","display_name":"Russian Science Foundation","ror":"https://ror.org/03y2gwe85"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3022979367.pdf","grobid_xml":"https://content.openalex.org/works/W3022979367.grobid-xml"},"referenced_works_count":158,"referenced_works":["https://openalex.org/W1582342805","https://openalex.org/W1602597014","https://openalex.org/W1632904338","https://openalex.org/W1735683374","https://openalex.org/W1768067213","https://openalex.org/W1964477207","https://openalex.org/W1969382230","https://openalex.org/W1974307280","https://openalex.org/W1976301815","https://openalex.org/W1986268392","https://openalex.org/W1989998611","https://openalex.org/W1999403102","https://openalex.org/W2002754533","https://openalex.org/W2004918900","https://openalex.org/W2009649840","https://openalex.org/W2014547920","https://openalex.org/W2018421689","https://openalex.org/W2020359958","https://openalex.org/W2020473652","https://openalex.org/W2025074675","https://openalex.org/W2026917976","https://openalex.org/W2031423988","https://openalex.org/W2040736753","https://openalex.org/W2055741709","https://openalex.org/W2058130458","https://openalex.org/W2058225831","https://openalex.org/W2061057444","https://openalex.org/W2064174165","https://openalex.org/W2064627656","https://openalex.org/W2068852170","https://openalex.org/W2070457877","https://openalex.org/W2075551106","https://openalex.org/W2076443835","https://openalex.org/W2082511674","https://openalex.org/W2082795977","https://openalex.org/W2085106295","https://openalex.org/W2087781990","https://openalex.org/W2088867588","https://openalex.org/W2090004724","https://openalex.org/W2090456048","https://openalex.org/W2099160677","https://openalex.org/W2103924242","https://openalex.org/W2104510699","https://openalex.org/W2111423624","https://openalex.org/W2112487751","https://openalex.org/W2115494622","https://openalex.org/W2117795567","https://openalex.org/W2120061656","https://openalex.org/W2129939988","https://openalex.org/W2144783676","https://openalex.org/W2149183402","https://openalex.org/W2149381851","https://openalex.org/W2154272596","https://openalex.org/W2155869496","https://openalex.org/W2156233344","https://openalex.org/W2158154607","https://openalex.org/W2159622766","https://openalex.org/W2162745520","https://openalex.org/W2165694975","https://openalex.org/W2212629349","https://openalex.org/W2237826830","https://openalex.org/W2294927917","https://openalex.org/W2316995090","https://openalex.org/W2344577268","https://openalex.org/W2347102183","https://openalex.org/W2355496089","https://openalex.org/W2433570839","https://openalex.org/W2472852704","https://openalex.org/W2474319713","https://openalex.org/W2474449496","https://openalex.org/W2488748284","https://openalex.org/W2519911390","https://openalex.org/W2520256066","https://openalex.org/W2565590011","https://openalex.org/W2571638380","https://openalex.org/W2589507764","https://openalex.org/W2607389085","https://openalex.org/W2609035077","https://openalex.org/W2667907301","https://openalex.org/W2731295011","https://openalex.org/W2737170029","https://openalex.org/W2737298436","https://openalex.org/W2742167711","https://openalex.org/W2750414851","https://openalex.org/W2751312375","https://openalex.org/W2759096297","https://openalex.org/W2767353752","https://openalex.org/W2768324896","https://openalex.org/W2781008213","https://openalex.org/W2788442037","https://openalex.org/W2788935121","https://openalex.org/W2789611191","https://openalex.org/W2791658630","https://openalex.org/W2791795670","https://openalex.org/W2792136072","https://openalex.org/W2792352422","https://openalex.org/W2796584644","https://openalex.org/W2799419788","https://openalex.org/W2800718271","https://openalex.org/W2804689657","https://openalex.org/W2887715598","https://openalex.org/W2896070320","https://openalex.org/W2898408013","https://openalex.org/W2899930826","https://openalex.org/W2900768728","https://openalex.org/W2901414189","https://openalex.org/W2901513545","https://openalex.org/W2902540982","https://openalex.org/W2904723369","https://openalex.org/W2905103858","https://openalex.org/W2910454105","https://openalex.org/W2912318433","https://openalex.org/W2913227771","https://openalex.org/W2913585615","https://openalex.org/W2914212843","https://openalex.org/W2918166602","https://openalex.org/W2919650122","https://openalex.org/W2921649571","https://openalex.org/W2922354437","https://openalex.org/W2934656438","https://openalex.org/W2941766054","https://openalex.org/W2941816803","https://openalex.org/W2942521218","https://openalex.org/W2942611039","https://openalex.org/W2943261081","https://openalex.org/W2943627940","https://openalex.org/W2945374036","https://openalex.org/W2945853742","https://openalex.org/W2946148649","https://openalex.org/W2949138741","https://openalex.org/W2953427954","https://openalex.org/W2956731794","https://openalex.org/W2956936996","https://openalex.org/W2960188650","https://openalex.org/W2963031695","https://openalex.org/W2963255765","https://openalex.org/W2967793847","https://openalex.org/W2971410519","https://openalex.org/W2971546509","https://openalex.org/W2978392882","https://openalex.org/W2985695709","https://openalex.org/W2988008393","https://openalex.org/W2990693715","https://openalex.org/W2991105408","https://openalex.org/W2992929975","https://openalex.org/W2993121097","https://openalex.org/W2994834904","https://openalex.org/W2996661070","https://openalex.org/W2997641877","https://openalex.org/W2997896219","https://openalex.org/W2999835074","https://openalex.org/W3006186050","https://openalex.org/W3006385478","https://openalex.org/W3011145490","https://openalex.org/W3011392050","https://openalex.org/W4211056710","https://openalex.org/W4244523227","https://openalex.org/W7155066828"],"related_works":["https://openalex.org/W6889726155","https://openalex.org/W2386116535","https://openalex.org/W3199835052","https://openalex.org/W7105794743","https://openalex.org/W2528248315","https://openalex.org/W2901550406","https://openalex.org/W3093388534","https://openalex.org/W1602597014","https://openalex.org/W4235355643","https://openalex.org/W4238696857"],"abstract_inverted_index":{"Polymyxins":[0],"are":[1,71,83,145],"vital":[2],"antibiotics":[3],"for":[4,63,86,91],"the":[5,34,59,92,101,110,124,133],"treatment":[6,93],"of":[7,89,94,103,113,135,139],"multiresistant":[8],"Gram-negative":[9],"ESKAPE":[10],"pathogen":[11],"infections.":[12],"However,":[13],"their":[14,20,28],"clinical":[15],"value":[16],"is":[17],"limited":[18],"by":[19],"high":[21],"nephrotoxicity":[22],"and":[23,31,49,55,67,75,81,97,116,127,130,155],"neurotoxicity,":[24],"as":[25,27],"well":[26],"poor":[29],"permeability":[30],"absorption":[32],"in":[33],"gastrointestinal":[35],"tract.":[36],"This":[37],"review":[38],"focuses":[39],"on":[40,147],"various":[41],"polymyxin":[42,47,69,90,107,136],"delivery":[43,70],"systems":[44,62,105],"that":[45,151],"improve":[46],"bioavailability":[48],"reduce":[50],"drug":[51],"toxicity":[52],"through":[53],"targeted":[54],"controlled":[56],"release.":[57],"Currently,":[58],"most":[60],"suitable":[61],"improving":[64],"oral,":[65],"inhalation,":[66],"parenteral":[68],"polymer":[72,79],"particles,":[73],"liposomes,":[74],"conjugates,":[76],"while":[77,119],"gels,":[78],"fibers,":[80],"membranes":[82],"attractive":[84],"materials":[85],"topical":[87],"administration":[88],"infected":[95],"wounds":[96],"burns.":[98],"In":[99],"general,":[100],"application":[102],"these":[104],"protects":[106],"molecules":[108],"from":[109],"negative":[111],"effects":[112],"both":[114],"physiological":[115],"pathological":[117],"factors":[118],"achieving":[120],"higher":[121],"concentrations":[122],"at":[123],"target":[125],"site":[126],"reducing":[128],"dosage":[129],"toxicity.":[131],"Improving":[132],"properties":[134],"will":[137],"be":[138],"great":[140],"interest":[141],"to":[142],"researchers":[143],"who":[144],"focused":[146],"developing":[148],"antimicrobial":[149],"drugs":[150],"show":[152],"increased":[153],"efficacy":[154],"safety.":[156]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":18},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-05-13T00:00:00"}