{"id":"https://openalex.org/W3022086271","doi":"https://doi.org/10.1021/ja00210a083","title":"Total synthesis of (.+-.)-ginkgolide B","display_name":"Total synthesis of (.+-.)-ginkgolide B","publication_year":1988,"publication_date":"1988-01-01","ids":{"openalex":"https://openalex.org/W3022086271","doi":"https://doi.org/10.1021/ja00210a083","mag":"3022086271","pmid":"https://pubmed.ncbi.nlm.nih.gov/31527923","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6746322"},"language":"en","primary_location":{"id":"doi:10.1021/ja00210a083","doi":"https://doi.org/10.1021/ja00210a083","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ja00210a083","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6746322","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012941338","display_name":"E.J. Corey","orcid":"https://orcid.org/0000-0002-1196-7896","observed_orcids":["https://orcid.org/0000-0002-1196-7896"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elias J. Corey","raw_affiliation_strings":["Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102108826","display_name":"Myung-chol Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Myung Chol. Kang","raw_affiliation_strings":["Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110100990","display_name":"Manoj C. Desai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Manoj C. Desai","raw_affiliation_strings":["Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041773055","display_name":"Arun Kumar Ghosh","orcid":"https://orcid.org/0000-0003-2472-1841","observed_orcids":["https://orcid.org/0000-0003-2472-1841"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arun K. Ghosh","raw_affiliation_strings":["Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022885535","display_name":"Ioannis N. Houpis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ioannis N. Houpis","raw_affiliation_strings":["Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I136199984"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":4.6178,"has_fulltext":false,"cited_by_count":190,"citation_normalized_percentile":{"value":0.96008417,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"110","issue":"2","first_page":"649","last_page":"651"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13221","display_name":"Biological Activity of Diterpenoids and Biflavonoids","score":0.8202999830245972,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13221","display_name":"Biological Activity of Diterpenoids and Biflavonoids","score":0.8202999830245972,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12846","display_name":"Ginkgo biloba and Cashew Applications","score":0.1062999963760376,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.015799999237060547,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ginkgolide-b","display_name":"ginkgolide B","score":0.9959999918937683},{"id":"https://openalex.org/keywords/total-synthesis","display_name":"total synthesis","score":0.9919999837875366},{"id":"https://openalex.org/keywords/ginkgo-biloba","display_name":"Ginkgo biloba","score":0.781000018119812},{"id":"https://openalex.org/keywords/sesquiterpene-lactones","display_name":"sesquiterpene lactones","score":0.6740000247955322},{"id":"https://openalex.org/keywords/natural-product-synthesis","display_name":"natural product synthesis","score":0.44600000977516174},{"id":"https://openalex.org/keywords/stereoselective-synthesis","display_name":"stereoselective synthesis","score":0.6629999876022339}],"concepts":[{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.7190743088722229},{"id":"https://openalex.org/C2778407487","wikidata":"https://www.wikidata.org/wiki/Q14565201","display_name":"Altmetrics","level":2,"score":0.607715904712677},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5388554930686951},{"id":"https://openalex.org/C518677369","wikidata":"https://www.wikidata.org/wiki/Q202833","display_name":"Social media","level":2,"score":0.5120318531990051},{"id":"https://openalex.org/C2778447006","wikidata":"https://www.wikidata.org/wiki/Q1156474","display_name":"Icon","level":2,"score":0.5054960250854492},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.4151294529438019},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.3938029408454895},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.36958038806915283},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1021/ja00210a083","doi":"https://doi.org/10.1021/ja00210a083","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ja00210a083","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},{"id":"pmid:31527923","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31527923","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6746322","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6746322","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Am Chem Soc","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6746322","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6746322","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Am Chem Soc","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5450191559","display_name":"DESIGN AND SYNTHESIS OF NONPEPTIDE PROTEASE INHIBITORS","funder_award_id":"R01GM053386","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W1982134056","https://openalex.org/W4230692984"],"related_works":["https://openalex.org/W2043381423","https://openalex.org/W1980819614","https://openalex.org/W2312023377","https://openalex.org/W6944630480","https://openalex.org/W2952781646","https://openalex.org/W2949898664","https://openalex.org/W4296847681","https://openalex.org/W1983267789","https://openalex.org/W2049484910","https://openalex.org/W2084929802"],"abstract_inverted_index":{"ADVERTISEMENT":[0],"RETURN":[1],"TO":[2],"ISSUEPREVArticleNEXTTotal":[3],"synthesis":[4],"of":[5,57,92,118],"(.+-.)-ginkgolide":[6],"BElias":[7],"J.":[8,24],"Corey,":[9],"Myung":[10],"Chol.":[11],"Kang,":[12],"Manoj":[13],"C.":[14],"Desai,":[15],"Arun":[16],"K.":[17],"Ghosh,":[18],"and":[19,67,72,101,145,162,178,180],"Ioannis":[20],"N.":[21],"HoupisCite":[22],"this:":[23],"Am.":[25],"Chem.":[26],"Soc.":[27],"1988,":[28],"110,":[29],"2,":[30],"649\u2013651Publication":[31],"Date":[32],"(Print):January":[33],"1,":[34],"1988Publication":[35],"History":[36],"Published":[37],"online1":[38],"May":[39],"2002Published":[40],"inissue":[41],"1":[42],"January":[43],"1988https://pubs.acs.org/doi/10.1021/ja00210a083https://doi.org/10.1021/ja00210a083research-articleACS":[44],"PublicationsRequest":[45],"reuse":[46],"permissionsArticle":[47],"Views7951Altmetric-Citations171LEARN":[48],"ABOUT":[49],"THESE":[50],"METRICSArticle":[51],"Views":[52],"are":[53,76,89],"the":[54,85,90,119,130,143,146,151,158,164],"COUNTER-compliant":[55],"sum":[56],"full":[58],"text":[59],"article":[60,124],"downloads":[61],"since":[62],"November":[63],"2008":[64],"(both":[65],"PDF":[66],"HTML)":[68],"across":[69],"all":[70],"institutions":[71],"individuals.":[73],"These":[74],"metrics":[75],"regularly":[77],"updated":[78,102],"to":[79,84],"reflect":[80],"usage":[81],"leading":[82],"up":[83],"last":[86],"few":[87],"days.Citations":[88],"number":[91],"other":[93],"articles":[94],"citing":[95],"this":[96],"article,":[97],"calculated":[98],"by":[99],"Crossref":[100,108],"daily.":[103],"Find":[104,154],"more":[105,155],"information":[106,156],"about":[107,142],"citation":[109],"counts.The":[110],"Altmetric":[111,159],"Attention":[112,160],"Score":[113,161],"is":[114,166],"a":[115,122,135],"quantitative":[116],"measure":[117],"attention":[120],"that":[121],"research":[123],"has":[125],"received":[126],"online.":[127],"Clicking":[128],"on":[129,157],"donut":[131],"icon":[132],"will":[133],"load":[134],"page":[136],"at":[137],"altmetric.com":[138],"with":[139,174],"additional":[140],"details":[141],"score":[144,165],"social":[147],"media":[148],"presence":[149],"for":[150],"given":[152],"article.":[153],"how":[163],"calculated.":[167],"Share":[168,183],"Add":[169],"toView":[170],"InAdd":[171],"Full":[172],"Text":[173],"ReferenceAdd":[175],"Description":[176],"ExportRISCitationCitation":[177],"abstractCitation":[179],"referencesMore":[181],"Options":[182],"onFacebookTwitterWechatLinked":[184],"InRedditEmail":[185],"Other":[186],"access":[187],"optionsGet":[188],"e-AlertscloseSupporting":[189],"Info":[190],"(1)\u00bbSupporting":[191],"Information":[192,194],"Supporting":[193],"Get":[195],"e-Alerts":[196]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2020-05-13T00:00:00"}