{"id":"https://openalex.org/W3021428890","doi":"https://doi.org/10.1093/chemse/bjaa030","title":"Activation of Calcium Binding Protein-ir Neurons in Medial Amygdala during Chemosignal Processing","display_name":"Activation of Calcium Binding Protein-ir Neurons in Medial Amygdala during Chemosignal Processing","publication_year":2020,"publication_date":"2020-05-02","ids":{"openalex":"https://openalex.org/W3021428890","doi":"https://doi.org/10.1093/chemse/bjaa030","mag":"3021428890","pmid":"https://pubmed.ncbi.nlm.nih.gov/32386197"},"language":"en","primary_location":{"id":"doi:10.1093/chemse/bjaa030","doi":"https://doi.org/10.1093/chemse/bjaa030","is_oa":true,"landing_page_url":"https://doi.org/10.1093/chemse/bjaa030","pdf_url":"https://academic.oup.com/chemse/article-pdf/45/6/439/33470547/bjaa030.pdf","source":{"id":"https://openalex.org/S8722945","display_name":"Chemical Senses","issn_l":"0379-864X","issn":["0379-864X","1464-3553"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Senses","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/chemse/article-pdf/45/6/439/33470547/bjaa030.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068295327","display_name":"Lindsey M. Biggs","orcid":"https://orcid.org/0000-0001-7700-6599","observed_orcids":["https://orcid.org/0000-0001-7700-6599"]},"institutions":[{"id":"https://openalex.org/I103163165","display_name":"Florida State University","ror":"https://ror.org/05g3dte14","country_code":"US","type":"education","lineage":["https://openalex.org/I103163165"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lindsey M Biggs","raw_affiliation_strings":["Program in Neuroscience and Department of Biological Science, Florida State University, Tallahassee, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Neuroscience and Department of Biological Science, Florida State University, Tallahassee, FL, USA","institution_ids":["https://openalex.org/I103163165"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109212832","display_name":"Michael J. Meredith","orcid":"https://orcid.org/0000-0001-8507-8584","observed_orcids":["https://orcid.org/0000-0001-8507-8584"]},"institutions":[{"id":"https://openalex.org/I103163165","display_name":"Florida State University","ror":"https://ror.org/05g3dte14","country_code":"US","type":"education","lineage":["https://openalex.org/I103163165"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael Meredith","raw_affiliation_strings":["Program in Neuroscience and Department of Biological Science, Florida State University, Tallahassee, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Neuroscience and Department of Biological Science, Florida State University, Tallahassee, FL, USA","institution_ids":["https://openalex.org/I103163165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5068295327","https://openalex.org/A5109212832"],"corresponding_institution_ids":["https://openalex.org/I103163165"],"apc_list":{"value":4317,"currency":"USD","value_usd":4317},"apc_paid":null,"fwci":0.1713,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.43400688,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"45","issue":"6","first_page":"439","last_page":"448"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medial-amygdala","display_name":"medial amygdala","score":0.9950000047683716},{"id":"https://openalex.org/keywords/chemosignals","display_name":"chemosignals","score":0.824999988079071},{"id":"https://openalex.org/keywords/social-communication","display_name":"social communication","score":0.578000009059906},{"id":"https://openalex.org/keywords/calcium-binding-proteins","display_name":"calcium-binding proteins","score":0.8109999895095825},{"id":"https://openalex.org/keywords/calbindin","display_name":"calbindin","score":0.9959999918937683},{"id":"https://openalex.org/keywords/calretinin","display_name":"calretinin","score":1.0},{"id":"https://openalex.org/keywords/parvalbumin","display_name":"parvalbumin","score":1.0},{"id":"https://openalex.org/keywords/gabaergic-neurons","display_name":"GABAergic neurons","score":0.9570000171661377},{"id":"https://openalex.org/keywords/sexual-experience","display_name":"sexual experience","score":0.6510000228881836},{"id":"https://openalex.org/keywords/syrian-hamster","display_name":"golden hamster","score":0.7689999938011169},{"id":"https://openalex.org/keywords/immediate-early-gene-expression","display_name":"immediate early gene expression","score":0.8199999928474426}],"concepts":[{"id":"https://openalex.org/C2779144063","wikidata":"https://www.wikidata.org/wiki/Q338924","display_name":"Amygdala","level":2,"score":0.9229854345321655},{"id":"https://openalex.org/C2781404787","wikidata":"https://www.wikidata.org/wiki/Q14908072","display_name":"Calretinin","level":3,"score":0.8034607172012329},{"id":"https://openalex.org/C141547260","wikidata":"https://www.wikidata.org/wiki/Q2720322","display_name":"Parvalbumin","level":2,"score":0.7878134250640869},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7738956212997437},{"id":"https://openalex.org/C26265296","wikidata":"https://www.wikidata.org/wiki/Q408713","display_name":"Calbindin","level":3,"score":0.691773533821106},{"id":"https://openalex.org/C2776287375","wikidata":"https://www.wikidata.org/wiki/Q3407681","display_name":"Basal forebrain","level":3,"score":0.5519737601280212},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5263320803642273},{"id":"https://openalex.org/C2779715522","wikidata":"https://www.wikidata.org/wiki/Q507027","display_name":"Forebrain","level":3,"score":0.5251942873001099},{"id":"https://openalex.org/C2780948618","wikidata":"https://www.wikidata.org/wiki/Q5421874","display_name":"Extended amygdala","level":4,"score":0.49610766768455505},{"id":"https://openalex.org/C2776032975","wikidata":"https://www.wikidata.org/wiki/Q5018833","display_name":"Calcium imaging","level":3,"score":0.45892173051834106},{"id":"https://openalex.org/C2778575167","wikidata":"https://www.wikidata.org/wiki/Q6573","display_name":"Hamster","level":2,"score":0.41166025400161743},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.2533952295780182},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.19669309258460999},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18519392609596252},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.13003966212272644},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1298970878124237},{"id":"https://openalex.org/C2778652331","wikidata":"https://www.wikidata.org/wiki/Q3122152","display_name":"Stria terminalis","level":3,"score":0.08242395520210266},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.07707801461219788},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/chemse/bjaa030","doi":"https://doi.org/10.1093/chemse/bjaa030","is_oa":true,"landing_page_url":"https://doi.org/10.1093/chemse/bjaa030","pdf_url":"https://academic.oup.com/chemse/article-pdf/45/6/439/33470547/bjaa030.pdf","source":{"id":"https://openalex.org/S8722945","display_name":"Chemical Senses","issn_l":"0379-864X","issn":["0379-864X","1464-3553"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Senses","raw_type":"journal-article"},{"id":"pmid:32386197","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32386197","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical senses","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/chemse/bjaa030","doi":"https://doi.org/10.1093/chemse/bjaa030","is_oa":true,"landing_page_url":"https://doi.org/10.1093/chemse/bjaa030","pdf_url":"https://academic.oup.com/chemse/article-pdf/45/6/439/33470547/bjaa030.pdf","source":{"id":"https://openalex.org/S8722945","display_name":"Chemical Senses","issn_l":"0379-864X","issn":["0379-864X","1464-3553"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Senses","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000894008","display_name":"Chemosensory Training Program (CTP)","funder_award_id":"T32DC000044","funder_id":"https://openalex.org/F4320337352","funder_display_name":"National Institute on Deafness and Other Communication Disorders"}],"funders":[{"id":"https://openalex.org/F4320337352","display_name":"National Institute on Deafness and Other Communication Disorders","ror":"https://ror.org/04mhx6838"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3021428890.pdf","grobid_xml":"https://content.openalex.org/works/W3021428890.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W565314664","https://openalex.org/W1533575559","https://openalex.org/W1991429950","https://openalex.org/W2004733543","https://openalex.org/W2022462550","https://openalex.org/W2030986988","https://openalex.org/W2031091121","https://openalex.org/W2053303406","https://openalex.org/W2056900903","https://openalex.org/W2058224978","https://openalex.org/W2061802640","https://openalex.org/W2071411229","https://openalex.org/W2080056868","https://openalex.org/W2090330732","https://openalex.org/W2093048200","https://openalex.org/W2093051637","https://openalex.org/W2099180447","https://openalex.org/W2100538095","https://openalex.org/W2101926440","https://openalex.org/W2102262129","https://openalex.org/W2107031757","https://openalex.org/W2127534323","https://openalex.org/W2159378661","https://openalex.org/W2165353016","https://openalex.org/W2167487265","https://openalex.org/W2199693290","https://openalex.org/W2429975388","https://openalex.org/W2523346077","https://openalex.org/W2608504239","https://openalex.org/W2886705363","https://openalex.org/W2905201435","https://openalex.org/W4300870773"],"related_works":["https://openalex.org/W2429975388","https://openalex.org/W6981932121","https://openalex.org/W2523346077","https://openalex.org/W7045989056","https://openalex.org/W300651475","https://openalex.org/W7096182003","https://openalex.org/W4210728553","https://openalex.org/W821466480","https://openalex.org/W1988847300","https://openalex.org/W7113126914"],"abstract_inverted_index":{"The":[0],"medial":[1,75,118,155,178],"amygdala":[2,42,76,139,156,179],"receives":[3],"sensory":[4],"input":[5],"from":[6],"chemical":[7,182],"signals":[8],"important":[9,58],"in":[10,27,35,129,154,174,184,198],"mammalian":[11],"social":[12,181],"communication.":[13],"As":[14],"measured":[15],"by":[16,187],"immediate":[17],"early":[18],"gene":[19],"expression,":[20,189],"its":[21],"responses":[22,53,107,158],"to":[23,44,48,108,121,135,180],"different":[24,96,114],"chemosignals":[25,111,122],"differ":[26],"the":[28,36,146,164,175],"spatial":[29,115],"patterns":[30,116],"of":[31,38,50,72,163,177],"neuronal":[32],"activation":[33],"and":[34,54,65,86,101,112,145],"types":[37],"cells":[39,103,144,185],"activated.":[40],"Medial":[41,138],"projections":[43],"basal":[45],"forebrain":[46],"contibute":[47],"generation":[49],"appropriate":[51],"behavioral":[52,202],"GABA":[55,192],"neurons":[56,77],"are":[57],"for":[59,81,171,201],"these":[60],"functions,":[61],"both":[62,104],"as":[63],"interneurons":[64],"projection":[66],"neurons.":[67],"Here":[68],"we":[69],"investigate":[70],"reponses":[71],"male":[73],"golden-hamster":[74],"expressing":[78],"immunoreactivity":[79],"(-ir)":[80],"calbindin":[82],"(CB),":[83],"calretinin":[84],"(CR)":[85],"parvalbumin":[87],"(PV),":[88],"calcium":[89],"binding":[90],"proteins":[91],"(CBPs)":[92],"which":[93,150],"can":[94],"distinguish":[95],"GABA-ergic":[97],"neuron":[98],"types.":[99],"CB-ir":[100],"CR-ir":[102],"had":[105],"significant":[106],"female":[109],"hamster":[110],"showed":[113],"across":[117],"amygdala.":[119],"Responses":[120],"(from":[123],"unfamiliar":[124],"females)":[125],"were":[126],"significantly":[127],"reduced":[128],"males":[130],"with":[131],"sexual":[132],"experience,":[133],"compared":[134],"na\u00efve":[136],"males.":[137],"did":[140,159],"not":[141,160],"express":[142,161],"PV-ir":[143],"adjacent":[147],"intercalated":[148],"nucleus,":[149],"has":[151],"been":[152],"implicated":[153],"chemosensory":[157,172],"any":[162],"CBPs":[165],"investigated":[166],"here.":[167],"This":[168],"additional":[169],"evidence":[170],"specificity":[173],"response":[176],"signals,":[183],"characterized":[186],"CBP":[188],"suggests":[190],"multiple":[191],"circuit":[193],"elements":[194],"may":[195],"be":[196],"involved":[197],"information":[199],"processing":[200],"response.":[203]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2020-05-13T00:00:00"}