{"id":"https://openalex.org/W3021209249","doi":"https://doi.org/10.1016/s0022-5347(05)65548-6","title":"ALTERATIONS IN GAP JUNCTION PROTEIN EXPRESSION IN HUMAN BENIGN PROSTATIC HYPERPLASIA AND PROSTATE CANCER","display_name":"ALTERATIONS IN GAP JUNCTION PROTEIN EXPRESSION IN HUMAN BENIGN PROSTATIC HYPERPLASIA AND PROSTATE CANCER","publication_year":2001,"publication_date":"2001-12-01","ids":{"openalex":"https://openalex.org/W3021209249","doi":"https://doi.org/10.1016/s0022-5347(05)65548-6","mag":"3021209249"},"language":"en","primary_location":{"id":"doi:10.1016/s0022-5347(05)65548-6","doi":"https://doi.org/10.1016/s0022-5347(05)65548-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-5347(05)65548-6","pdf_url":null,"source":{"id":"https://openalex.org/S30525748","display_name":"The Journal of Urology","issn_l":"0022-5347","issn":["0022-5347","1527-3792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Urology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"HELGA HABERMANN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["AT","US"],"is_corresponding":false,"raw_author_name":"HELGA HABERMANN","raw_affiliation_strings":["From the Departments of Urology and Otorhinolaryngology-Head and Neck Surgery, University of Graz, Graz, Austria, and Department of Pathology, Provident Hospital and Department of Urology, University of Illinois at Chicago, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Urology and Otorhinolaryngology-Head and Neck Surgery, University of Graz, Graz, Austria, and Department of Pathology, Provident Hospital and Department of Urology, University of Illinois at Chicago, Chicago, Illinois","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109221796","display_name":"Vera Ray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["AT","US"],"is_corresponding":false,"raw_author_name":"VERA RAY","raw_affiliation_strings":["From the Departments of Urology and Otorhinolaryngology-Head and Neck Surgery, University of Graz, Graz, Austria, and Department of Pathology, Provident Hospital and Department of Urology, University of Illinois at Chicago, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Urology and Otorhinolaryngology-Head and Neck Surgery, University of Graz, Graz, Austria, and Department of Pathology, Provident Hospital and Department of Urology, University of Illinois at Chicago, Chicago, Illinois","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105777458","display_name":"Walter Habermann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["AT","US"],"is_corresponding":false,"raw_author_name":"WALTER HABERMANN","raw_affiliation_strings":["From the Departments of Urology and Otorhinolaryngology-Head and Neck Surgery, University of Graz, Graz, Austria, and Department of Pathology, Provident Hospital and Department of Urology, University of Illinois at Chicago, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Urology and Otorhinolaryngology-Head and Neck Surgery, University of Graz, Graz, Austria, and Department of Pathology, Provident Hospital and Department of Urology, University of Illinois at Chicago, Chicago, Illinois","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I39422238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049719845","display_name":"Gail S. Prins","orcid":"https://orcid.org/0000-0002-9044-4734","observed_orcids":["https://orcid.org/0000-0002-9044-4734"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["AT","US"],"is_corresponding":false,"raw_author_name":"GAIL S. PRINS","raw_affiliation_strings":["From the Departments of Urology and Otorhinolaryngology-Head and Neck Surgery, University of Graz, Graz, Austria, and Department of Pathology, Provident Hospital and Department of Urology, University of Illinois at Chicago, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Urology and Otorhinolaryngology-Head and Neck Surgery, University of Graz, Graz, Austria, and Department of Pathology, Provident Hospital and Department of Urology, University of Illinois at Chicago, Chicago, Illinois","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I39422238"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.5781,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.64730418,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"166","issue":"6","first_page":"2267","last_page":"2272"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11480","display_name":"Connexins and lens biology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11480","display_name":"Connexins and lens biology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gap-junctions","display_name":"gap junctions","score":0.7879999876022339},{"id":"https://openalex.org/keywords/connexin-32","display_name":"connexin 32","score":0.9539999961853027},{"id":"https://openalex.org/keywords/connexin-43","display_name":"connexin 43","score":1.0},{"id":"https://openalex.org/keywords/benign-prostatic-hyperplasia","display_name":"benign prostatic hyperplasia","score":0.9929999709129333},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":1.0},{"id":"https://openalex.org/keywords/intercellular-communication","display_name":"intercellular communication","score":0.7979999780654907},{"id":"https://openalex.org/keywords/bladder-outlet-obstruction","display_name":"bladder outlet obstruction","score":0.7549999952316284},{"id":"https://openalex.org/keywords/immunolocalization","display_name":"immunolocalization","score":0.5979999899864197},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.5289999842643738},{"id":"https://openalex.org/keywords/prostatic-epithelium","display_name":"prostate epithelium","score":0.5180000066757202},{"id":"https://openalex.org/keywords/bladder-cancer-staging","display_name":"bladder cancer staging","score":0.32100000977516174},{"id":"https://openalex.org/keywords/bladder-cancer-prognosis","display_name":"bladder cancer prognosis","score":0.4519999921321869},{"id":"https://openalex.org/keywords/bladder-cancer-treatment-outcomes","display_name":"bladder cancer treatment outcomes","score":0.36399999260902405}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9253619313240051},{"id":"https://openalex.org/C2777562237","wikidata":"https://www.wikidata.org/wiki/Q835051","display_name":"Hyperplasia","level":2,"score":0.7861718535423279},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.6612056493759155},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5920429825782776},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.5848117470741272},{"id":"https://openalex.org/C87874733","wikidata":"https://www.wikidata.org/wiki/Q18039844","display_name":"PCA3","level":4,"score":0.5177696943283081},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.49460121989250183},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3666991591453552},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3441043496131897},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3328699469566345},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3295617401599884},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31424206495285034},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09821605682373047},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0022-5347(05)65548-6","doi":"https://doi.org/10.1016/s0022-5347(05)65548-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-5347(05)65548-6","pdf_url":null,"source":{"id":"https://openalex.org/S30525748","display_name":"The Journal of Urology","issn_l":"0022-5347","issn":["0022-5347","1527-3792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Urology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.6200000047683716,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2871837763","display_name":null,"funder_award_id":"DK 40890","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5849790099","display_name":"Development Estrogenization of the Rat Prostate Gland","funder_award_id":"R01DK040890","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1887945709","https://openalex.org/W1973609567","https://openalex.org/W1974667009","https://openalex.org/W1977845454","https://openalex.org/W1984038646","https://openalex.org/W1985406943","https://openalex.org/W1988316236","https://openalex.org/W1991806877","https://openalex.org/W1995748663","https://openalex.org/W1997348862","https://openalex.org/W2000063742","https://openalex.org/W2006109999","https://openalex.org/W2011007333","https://openalex.org/W2020294738","https://openalex.org/W2022144539","https://openalex.org/W2022379190","https://openalex.org/W2022963363","https://openalex.org/W2032588123","https://openalex.org/W2039398614","https://openalex.org/W2040418071","https://openalex.org/W2046577989","https://openalex.org/W2052104049","https://openalex.org/W2059335883","https://openalex.org/W2059417273","https://openalex.org/W2075999602","https://openalex.org/W2089827066","https://openalex.org/W2166809896","https://openalex.org/W2168736661","https://openalex.org/W2339312596","https://openalex.org/W2396961956","https://openalex.org/W2398157797","https://openalex.org/W4247705376","https://openalex.org/W4248655085"],"related_works":["https://openalex.org/W1984038646","https://openalex.org/W2024964343","https://openalex.org/W2059417273","https://openalex.org/W4244519358","https://openalex.org/W2509835798","https://openalex.org/W2014941365","https://openalex.org/W2008367486","https://openalex.org/W2007383860","https://openalex.org/W1509340951","https://openalex.org/W2142961429"],"abstract_inverted_index":{"No":[0],"AccessJournal":[1],"of":[2,102,115,180,202,221,242,268,279,300,312,332,367,432,468,498,540,597,621,639,650,672,676,710,724,738,744,769,778,845,861,865,908,913,930,945,968,1003,1014,1056,1106,1137,1156,1177,1185,1191,1197,1200,1232,1255,1259,1271],"UrologyCLINICAL":[3],"UROLOGY:":[4],"Original":[5],"Articles1":[6],"Dec":[7],"2001ALTERATIONS":[8],"IN":[9,14,24,29,1275,1280],"GAP":[10,25,1276],"JUNCTION":[11,26,1277],"PROTEIN":[12,27,1278],"EXPRESSION":[13,28,1279],"HUMAN":[15,30,1281],"BENIGN":[16,31,1282],"PROSTATIC":[17,32,1283],"HYPERPLASIA":[18,33,1284],"AND":[19,34,1285],"PROSTATE":[20,35,1286],"CANCERis":[21],"corrected":[22],"byALTERATIONS":[23],"CANCER":[36,1287],"HELGA":[37,47,1307],"HABERMANN,":[38,42],"VERA":[39,56,1314],"RAY,":[40],"WALTER":[41,65,1321],"and":[43,74,112,136,172,184,198,207,219,224,260,266,298,303,335,342,345,358,365,406,435,456,486,520,542,557,580,594,669,674,795,800,888,928,949,965,987,1070,1179,1181,1189,1195,1220,1225,1246],"GAIL":[44,75,1328],"S.":[45,76,78,1329],"PRINS":[46,79,1330],"HABERMANNHELGA":[48],"HABERMANN":[49,67,1308,1322],"More":[50,59,68,80,1309,1316,1323,1331],"articles":[51,60,69,81,1310,1317,1324,1332],"by":[52,61,70,82,226,429,775,803,1141,1207,1298,1311,1318,1325,1333],"this":[53,62,71,83,1312,1319,1326,1334],"author":[54,63,72,84,1313,1320,1327,1335],",":[55,64,73],"RAYVERA":[57],"RAY":[58,1315],"HABERMANNWALTER":[66],"PRINSGAIL":[77],"View":[85],"All":[86,1337],"Author":[87],"Informationhttps://doi.org/10.1016/S0022-5347(05)65548-6AboutFull":[88],"TextPDF":[89],"ToolsAdd":[90],"to":[91,120,132,148,193,251,273,722,882,1021,1089],"favoritesDownload":[92],"CitationsTrack":[93],"CitationsPermissionsReprints":[94],"ShareFacebookLinked":[95],"InTwitterEmail":[96],"Abstract":[97],"Purpose:":[98],"Gap":[99,483,694,1038],"junctions":[100,740,910],"composed":[101],"connexin":[103,116,134,151,170,222,234,248,258,301,317,325,340,356,383,392,433,448,748,779],"proteins":[104,891],"have":[105,121,411,451],"an":[106,1117],"essential":[107],"role":[108,123,413,453,497,907],"in":[109,124,142,157,167,177,264,295,320,328,362,404,414,440,447,454,503,536,599,616,643,680,741,753,793,819,841,892,911,952,983,1009,1062,1108,1119,1159,1228],"intercellular":[110,400,422,470,501,558],"communication":[111,401,423,485,502,679,792,1140,1158],"differentiation.":[113],"Dysregulation":[114],"expression":[117,140,152,174,319,431,449,615,638,649,668,777,818,1105],"is":[118,145,402,424,426,1019,1087,1114],"believed":[119],"a":[122,178,292,412,452,714],"carcinogenesis.":[125],"The":[126,496,906,963,1084,1134],"human":[127,377,645,682,770,822,866,1161],"prostate":[128,143,168,185,257,329,378,418,443,683,771,797,867,947,984,1162],"has":[129,153],"been":[130,155],"reported":[131,156],"express":[133],"32":[135,171,223,249,261,304,359,393,436,749,1151],"43.":[137,656],"However,":[138],"the":[139,164,215,240,243,280,296,465,537,617,711,846,862,893,914,969,1004,1012,1015,1022,1057,1109,1120,1175,1229],"pattern":[141,220],"cancer":[144,186,209,330,419,772],"controversial,":[146],"while":[147],"our":[149],"knowledge":[150],"not":[154],"benign":[158,931],"prostatic":[159,823,932],"hyperplasia":[160],"(BPH).":[161],"To":[162],"understand":[163],"potential":[165],"involvement":[166],"disease":[169],"43":[173,205,225,235,259,302,318,341,357,384,434,614,817],"was":[175,237,291,326],"evaluated":[176,213],"series":[179],"normal":[181,256,281,376,794],"prostate,":[182],"BPH":[183,206,288,313,397,415],"specimens":[187,232,289],"that":[188,1025],"were":[189,212,262,283,337,347,360],"surgically":[190],"removed":[191],"due":[192],"bladder":[194],"outlet":[195],"obstruction.":[196],"Materials":[197],"Methods:":[199],"Frozen":[200],"sections":[201],"23":[203,941],"normal,":[204],"40":[208],"involved":[210],"prostates":[211],"for":[214,339,349,713],"presence,":[216],"staining":[217],"intensity":[218,299],"immunocytochemical":[227],"testing.":[228],"Results:":[229],"In":[230,255,287,309,323,352,375,396,417],"all":[231],"examined":[233],"stain":[236,275],"punctate":[238],"along":[239],"borders":[241],"basal":[244,379,863],"epithelial":[245,253,307,405,798,885],"cells,":[246,408],"whereas":[247,387],"immunolocalized":[250],"luminal":[252,388],"cells.":[254,308,322,684,825,1164],"present":[263,361],"87%":[265],"65%":[267,334],"specimens,":[269,331],"respectively,":[270,344,369],"at":[271,370,1011,1202],"low":[272,371],"moderate":[274],"intensity.":[276,373],"Importantly":[277],"none":[278],"samples":[282,314],"negative":[284,338,348],"foreach":[285],"connexin.":[286],"there":[290],"marked":[293],"increase":[294,1118],"incidence":[297],"immunostaining":[305,372],"within":[306,623],"addition,":[310],"23%":[311],"showed":[315],"strong":[316],"stromal":[321,407,950],"contrast,":[324],"decreased":[327,430],"which":[333,409],"38%":[336],"32,":[343],"28%":[346],"each":[350],"type.":[351],"poorly":[353,441],"differentiated":[354,442],"tumors":[355],"only":[363],"10%":[364],"40%":[366],"tumors,":[368],"Conclusions:":[374],"cells":[380,389,720,746,799,864],"communicate":[381,390],"via":[382,391],"gap":[385,394,398,420,499,572,601,640,652,677,739,889,909,1006,1058],"junctions,":[386],"junctions.":[395,602],"junctional":[399,421,484,500,678,1007],"increased":[403],"may":[410,450],"pathogenesis.":[416],"decreased,":[425],"as":[427],"indicated":[428],"with":[437,463,747,1116],"severe":[438],"loss":[439],"cancer.":[444],"These":[445],"alterations":[446],"dedifferentiation":[455],"tumor":[457,745,1163],"progression.":[458],"References":[459],"1":[460],":":[461,482,495,515,533,554,570,591,612,636,666,693,708,736,767,790,814,837,858,879,905,926,942,962,980,1001,1037,1054,1083,1103,1133,1152],"Connections":[462],"connexins:":[464],"molecular":[466],"basis":[467],"direct":[469],"signaling.":[471],"Eur":[472],"J":[473,726,1073],"Biochem1996;":[474,562],"238:":[475],"1.":[476],"Crossref,":[477,528,549,565,586,607,631,661,688,703,731,762,785,809,832,853,874,900,921,957,975,996,1032,1049,1078,1098,1128,1147],"Medline,":[478,491,511,529,550,566,587,608,632,662,689,704,732,763,786,810,833,854,875,901,922,938,958,976,997,1033,1050,1079,1099,1129,1148,1171],"Google":[479,492,512,530,551,567,588,609,633,663,690,705,733,764,787,811,834,855,876,902,923,939,959,977,998,1034,1051,1080,1100,1130,1149,1172],"Scholar":[480,493,513,531,552,568,589,610,634,664,691,706,734,765,788,812,835,856,877,903,924,940,960,978,999,1035,1052,1081,1101,1131,1150,1173],"2":[481],"development.":[487,582],"TINS1989;":[488],"12:":[489],"12.":[490,1031],"3":[494],"neoplasia.":[504],"Ann":[505],"Clin":[506],"Lab":[507],"Sci1994;":[508],"24:":[509,783],"216.":[510],"4":[514],"Desmosomes:":[516],"differentiation,":[517],"development,":[518],"dynamics":[519],"disease.":[521],"Curr":[522],"Opin":[523],"Cell":[524],"Biol1996;":[525],"8:":[526,973],"670.":[527],"5":[532],"Molecular":[534,1066],"interactions":[535,1024],"submembrane":[538],"plaque":[539],"cell-cell":[541,715,1139,1157],"cell-matrix":[543],"adhesions.":[544],"Acta":[545],"Anat1995;":[546],"154:":[547],"46.":[548],"6":[553],"Connexins,":[555],"connexons,":[556],"communication.":[559],"Annu":[560],"Rev":[561],"65:":[563],"475.":[564],"7":[569],"Multiple":[571],"junction":[573,641,653,695,890,1059],"genes":[574],"are":[575],"utilized":[576],"during":[577,1112],"rat":[578,848,895,1110],"skin":[579],"hair":[581],"Development1992;":[583],"116:":[584,1076],"639.":[585],"8":[590],"Developmental":[592,880],"regulation":[593,802,986,1136],"structural":[595],"organization":[596],"connexins":[598],"epidermal":[600],"Dev":[603,627,781,1028],"Biol1994;":[604,1029],"164:":[605],"183.":[606],"9":[611],"Connexin":[613,655,816],"mouse":[618],"embryo:":[619],"localization":[620,840],"transcripts":[622],"developmentally":[624],"significant":[625],"domains.":[626],"Dynam1992;":[628],"194:":[629],"261.":[630],"10":[635],"Aberrant":[637],"gene":[642,654,697,712,985,1086],"primary":[644],"hepatocellular":[646],"carcinomas:":[647],"Increased":[648,1104],"cardiac-type":[651],"Mol":[657,805],"Carcin1990;":[658],"3:":[659],"273.":[660],"11":[665],"Impaired":[667],"posttranslational":[670],"processing":[671],"Connexin43":[673],"downregulation":[675],"neoplastic":[681,796],"Prostate1999;":[685],"38:":[686],"55.":[687],"12":[692],"protein":[696,717,1008,1060],"suppresses":[698],"tumorigenicity.":[699],"Carcinogenesis1993;":[700],"14:":[701],"1073.":[702],"13":[707],"Incorporation":[709],"channel":[716],"into":[718],"transformed":[719],"leads":[721],"normalization":[723],"growth.":[725],"Membrane":[727],"Biol1991;":[728],"124:":[729],"207.":[730],"14":[735],"Involvement":[737],"tumorigenesis:":[742],"transfection":[743],"cDNA":[750],"retards":[751],"growth":[752,774],"vivo.":[754],"Proc":[755,989,1091],"Natl":[756,990],"Acad":[757,991],"Sci":[758,992],"USA1991;":[759],"88:":[760],"10701.":[761],"15":[766],"Suppression":[768],"cell":[773,843,886],"forced":[776],"genes.":[780],"Gen1999;":[782],"91.":[784],"16":[789],"Gap-junctional":[791],"its":[801],"cAMP.":[804],"Carcin1996;":[806],"15:":[807,936],"18.":[808],"17":[813],"Reduced":[815],"high":[820],"grade,":[821],"adenocarcinoma":[824],"Biochem":[826],"Biophy":[827],"Res":[828,870],"Com1996;":[829],"227:":[830],"64.":[831],"18":[836],"Androgen":[838],"receptor":[839],"different":[842],"types":[844],"adult":[847,894],"prostate.":[849,896,970],"Endocrinology1991;":[850],"129:":[851],"3187.":[852],"19":[857],"Unique":[859],"features":[860],"epithelium.":[868],"Microscop":[869],"Tech2000;":[871],"51:":[872],"436.":[873],"20":[878],"exposure":[881],"estrogens":[883],"alters":[884],"adhesion":[887],"Endocrinology2001;":[897],"142:":[898],"359.":[899],"21":[904],"patterning":[912],"chick":[915,1016,1064],"limb":[916,1017],"bud.":[917],"Development1990;":[918],"108:":[919],"623.":[920],"22":[925],"Origin":[927],"evolution":[929],"enlargement.":[933],"Invest":[934],"Urol1978;":[935],"340.":[937],"Morphological":[943],"analogies":[944],"fetal":[946],"stroma":[948],"nodules":[951],"BPH.":[953],"Prostate1997;":[954],"31:":[955],"234.":[956],"24":[961],"endocrinology":[964],"developmental":[966],"biology":[967],"Endo":[971,1143],"Rev1987;":[972],"338.":[974],"25":[979],"Cell-cell":[981],"interaction":[982],"cytodifferentiation.":[988],"USA1997;":[993],"94:":[994],"10705.":[995],"26":[1000],"Expression":[1002,1055],"connexin43":[1005,1061,1085],"tissues":[1010],"tip":[1013],"bud":[1018],"related":[1020],"epithelial-mesenchymal":[1023],"mediate":[1026],"morphogenesis.":[1027],"161:":[1030],"27":[1036],"junctions:":[1039],"new":[1040,1042,1044],"tools,":[1041],"answers,":[1043],"questions.":[1045],"Neuron1991;":[1046],"6:":[1047],"305.":[1048],"28":[1053],"embryonic":[1063],"lens:":[1065],"cloning,":[1067],"ultrastructural":[1068],"localization,":[1069],"post-translational":[1071],"phosphorylation.":[1072,1142],"Mem":[1074],"Biol1990;":[1075],"163.":[1077],"29":[1082],"responsive":[1088],"oestrogen.":[1090],"R":[1092],"Soc":[1093],"Lond":[1094],"B1994;":[1095],"255:":[1096],"125.":[1097],"30":[1102],"connexin-43":[1107],"myometrium":[1111],"labor":[1113],"associated":[1115],"plasma":[1121],"estrogen:":[1122],"progesterone":[1123],"ratio.":[1124],"Endocrinology1993;":[1125],"132:":[1126],"2380.":[1127],"31":[1132],"hormone-induced":[1135],"contact-dependent":[1138],"Rev1990;":[1144],"11:":[1145],"302.":[1146],"Laser":[1153],"scanning":[1154],"analysis":[1155],"cultured":[1160],"Anal":[1165],"Quan":[1166],"Cytol":[1167],"Hist1999;":[1168],"21:":[1169],"54.":[1170],"From":[1174],"Departments":[1176],"Urology":[1178],"Otorhinolaryngology-Head":[1180],"Neck":[1182],"Surgery,":[1183],"University":[1184,1199],"Graz,":[1186,1187],"Austria,":[1188],"Department":[1190,1196],"Pathology,":[1192],"Provident":[1193],"Hospital":[1194],"Urology,":[1198,1233,1260],"Illinois":[1201],"Chicago,":[1203,1204],"Illinois\u00a9":[1205],"2001":[1206,1297],"American":[1208,1299],"Urological":[1209,1300],"Association,":[1210,1301],"Inc.FiguresReferencesRelatedDetailsCited":[1211],"byNguyen":[1212],"D,":[1213],"Dey":[1214],"A,":[1215,1243],"Lang":[1216],"R,":[1217],"Ventura":[1218],"S":[1219],"Exintaris":[1221],"B":[1222],"(2010)":[1223],"Contractility":[1224],"Pacemaker":[1226],"Cells":[1227],"Prostate":[1230,1250],"GlandJournal":[1231],"VOL.":[1234,1261],"185,":[1235],"NO.":[1236,1263],"1,":[1237],"(347-351),":[1238],"Online":[1239,1266],"publication":[1240,1267],"date:":[1241,1268],"1-Jan-2011.BARQAWI":[1242],"THOMPSON":[1244],"I":[1245],"CRAWFORD":[1247],"E":[1248],"(2018)":[1249],"Cancer":[1251],"Chemoprevention:":[1252],"An":[1253],"Overview":[1254],"United":[1256],"States":[1257],"TrialsJournal":[1258],"171,":[1262],"2S,":[1264],"(S5-S9),":[1265],"1-Feb-2004.Related":[1269],"articlesJournal":[1270],"Urology9":[1272],"Nov":[1273],"2018ALTERATIONS":[1274],"Volume":[1288],"166Issue":[1289],"6December":[1290],"2001Page:":[1291],"2267-2272":[1292],"Advertisement":[1293,1338],"Copyright":[1294],"&":[1295],"Permissions\u00a9":[1296],"Inc.KeywordsprostateGTPase-activating":[1302],"proteinsprostatic":[1303],"neoplasmsprostatic":[1304],"hyperplasiaconnexinsMetricsAuthor":[1305],"Information":[1306],"Expand":[1336],"PDF":[1339],"downloadLoading":[1340],"...":[1341]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2020-05-13T00:00:00"}