{"id":"https://openalex.org/W3021069032","doi":null,"title":"Using Bioinformatics Tools to Evaluate Potential Risks of Food Allergy and to Predict Microbiome Functionality","display_name":"Using Bioinformatics Tools to Evaluate Potential Risks of Food Allergy and to Predict Microbiome Functionality","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3021069032","mag":"3021069032"},"language":"en","primary_location":{"id":"pmh:oai:digitalcommons.unl.edu:foodscidiss-1109","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.unl.edu/foodscidiss/106","pdf_url":"https://digitalcommons.unl.edu/context/foodscidiss/article/1109/viewcontent/COMPLIANT_unl_foodscidiss_1109.pdf","source":{"id":"https://openalex.org/S4306400577","display_name":"Lincoln (University of Nebraska)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114395901","host_organization_name":"University of Nebraska\u2013Lincoln","host_organization_lineage":["https://openalex.org/I114395901"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Department of Food Science and Technology: Dissertations, Theses, and Student Research","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://digitalcommons.unl.edu/context/foodscidiss/article/1109/viewcontent/COMPLIANT_unl_foodscidiss_1109.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010401853","display_name":"Mohamed Abdelmoteleb","orcid":"https://orcid.org/0000-0001-9453-3219","observed_orcids":["https://orcid.org/0000-0001-9453-3219"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Mohamed Abdelmoteleb","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9453-3219","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5010401853"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.9312000274658203,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.9312000274658203,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":0.038100000470876694,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/novel-foods","display_name":"novel foods","score":0.9819999933242798},{"id":"https://openalex.org/keywords/genetically-modified-organisms","display_name":"genetically modified organisms","score":0.9520000219345093},{"id":"https://openalex.org/keywords/ige-cross-reactivity","display_name":"IgE cross-reactivity","score":0.8939999938011169},{"id":"https://openalex.org/keywords/fusarium","display_name":"Fusarium","score":0.7480000257492065},{"id":"https://openalex.org/keywords/acheta-domesticus","display_name":"Acheta domesticus","score":0.6259999871253967},{"id":"https://openalex.org/keywords/shrimp-allergy","display_name":"shrimp allergy","score":0.7929999828338623},{"id":"https://openalex.org/keywords/rumen-microbiome","display_name":"rumen microbiome","score":0.8140000104904175},{"id":"https://openalex.org/keywords/methane-emissions","display_name":"methane emissions","score":0.5120000243186951},{"id":"https://openalex.org/keywords/dietary-nitrate","display_name":"dietary nitrate","score":0.8740000128746033},{"id":"https://openalex.org/keywords/cattle-performance","display_name":"cattle performance","score":0.6499999761581421},{"id":"https://openalex.org/keywords/hydrogen-production","display_name":"hydrogen production","score":0.5559999942779541}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.7565488815307617},{"id":"https://openalex.org/C2776027960","wikidata":"https://www.wikidata.org/wiki/Q769815","display_name":"Food allergy","level":3,"score":0.5099078416824341},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.383451908826828},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3703930675983429},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.35521137714385986},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3438284993171692},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.3326985836029053},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3049347698688507},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30214330554008484},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.30029091238975525},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.20893529057502747}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:digitalcommons.unl.edu:foodscidiss-1109","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.unl.edu/foodscidiss/106","pdf_url":"https://digitalcommons.unl.edu/context/foodscidiss/article/1109/viewcontent/COMPLIANT_unl_foodscidiss_1109.pdf","source":{"id":"https://openalex.org/S4306400577","display_name":"Lincoln (University of Nebraska)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114395901","host_organization_name":"University of Nebraska\u2013Lincoln","host_organization_lineage":["https://openalex.org/I114395901"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Department of Food Science and Technology: Dissertations, Theses, and Student Research","raw_type":"text"},{"id":"pmh:oai:digitalcommons.unl.edu:dissertations-16018","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.unl.edu/dissertations/AAI27955787","pdf_url":null,"source":{"id":"https://openalex.org/S4306400577","display_name":"Lincoln (University of Nebraska)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114395901","host_organization_name":"University of Nebraska\u2013Lincoln","host_organization_lineage":["https://openalex.org/I114395901"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ETD collection for University of Nebraska-Lincoln","raw_type":"text"},{"id":"mag:3021069032","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1109&context=foodscidiss","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:digitalcommons.unl.edu:foodscidiss-1109","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.unl.edu/foodscidiss/106","pdf_url":"https://digitalcommons.unl.edu/context/foodscidiss/article/1109/viewcontent/COMPLIANT_unl_foodscidiss_1109.pdf","source":{"id":"https://openalex.org/S4306400577","display_name":"Lincoln (University of Nebraska)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114395901","host_organization_name":"University of Nebraska\u2013Lincoln","host_organization_lineage":["https://openalex.org/I114395901"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Department of Food Science and Technology: Dissertations, Theses, and Student Research","raw_type":"text"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.9208999872207642,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3969975058","display_name":null,"funder_award_id":"2018\u201068003\u201027545","funder_id":"https://openalex.org/F4320332299","funder_display_name":"National Institute of Food and Agriculture"},{"id":"https://openalex.org/G5201722840","display_name":null,"funder_award_id":"2018-68003-27545","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"},{"id":"https://openalex.org/G7595281299","display_name":null,"funder_award_id":"2018-67015-27496","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"},{"id":"https://openalex.org/G7963278094","display_name":null,"funder_award_id":"2018-67015-27496","funder_id":"https://openalex.org/F4320332299","funder_display_name":"National Institute of Food and Agriculture"}],"funders":[{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320332299","display_name":"National Institute of Food and Agriculture","ror":"https://ror.org/05qx3fv49"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3021069032.pdf","grobid_xml":"https://content.openalex.org/works/W3021069032.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1963723331","https://openalex.org/W1965266920","https://openalex.org/W1979623975","https://openalex.org/W1994814715","https://openalex.org/W2001604363","https://openalex.org/W2001624721","https://openalex.org/W2011826478","https://openalex.org/W2012288325","https://openalex.org/W2015527152","https://openalex.org/W2055755639","https://openalex.org/W2056279562","https://openalex.org/W2060582420","https://openalex.org/W2070261938","https://openalex.org/W2072970694","https://openalex.org/W2079959646","https://openalex.org/W2103441770","https://openalex.org/W2107772251","https://openalex.org/W2112071632","https://openalex.org/W2117457769","https://openalex.org/W2131026689","https://openalex.org/W2138767454","https://openalex.org/W2143485490","https://openalex.org/W2208185810","https://openalex.org/W2401404581","https://openalex.org/W2513506562","https://openalex.org/W2550816984","https://openalex.org/W2575397500"],"related_works":["https://openalex.org/W3107991355","https://openalex.org/W2281797260","https://openalex.org/W2012037212","https://openalex.org/W3008949490","https://openalex.org/W4281739484","https://openalex.org/W2551526007","https://openalex.org/W1634411608","https://openalex.org/W4399546386","https://openalex.org/W4396837587","https://openalex.org/W2999134788"],"abstract_inverted_index":{"Novel":[0],"foods":[1,53,97],"and":[2,13,54,86,108,120,137,155,168,182,237,257,263,272,283,286,304,318,330],"Genetically":[3],"Engineered":[4],"(GE)":[5],"organisms":[6,101],"are":[7,177],"being":[8],"developed":[9,228],"for":[10,49,105,189,239,276],"nutritional,":[11],"industrial,":[12],"environmental":[14],"applications.":[15],"Dietary":[16],"interventions":[17,65],"have":[18,33,123,140],"been":[19,34,124,141],"used":[20,35,142,275],"recently":[21],"to":[22,36,70,102,126,143,151,159,173,186,210,234,268,290,345],"mitigate":[23],"methane":[24,71,264,292,335],"emissions":[25],"in":[26,73,82,95,180,297,325,342,347],"ruminants.":[27,74],"In":[28,225],"this":[29],"project,":[30],"bioinformatics":[31],"tools":[32,148],"answer":[37,76],"two":[38,165],"main":[39],"questions.":[40],"The":[41,57,164],"first":[42,78],"question":[43,59],"is":[44,60,207],"the":[45,61,77,83,187,193,213,247,252],"potential":[46,128,145],"allergy":[47,107],"risks":[48],"consumption":[50],"of":[51,63,92,192,242,254,279,312,334],"novel":[52,96,243],"GE":[55,121,214],"organisms.":[56],"second":[58,248],"effects":[62],"dietary":[64,255],"on":[66,259],"microbiome":[67,281],"functionality":[68],"related":[69],"production":[72],"To":[75,266],"question,":[79,249,269],"regulatory":[80],"authorities":[81],"United":[84],"States":[85],"Europe":[87],"now":[88],"expect":[89],"an":[90],"evaluation":[91,191],"new":[93],"proteins":[94,238],"or":[98,161,220],"genetically":[99],"engineered":[100],"be":[103],"evaluated":[104],"possible":[106],"Celiac":[109],"disease":[110],"(CeD)":[111],"risk.":[112],"Two":[113],"microalgal":[114,166],"species,":[115,184],"a":[116,229,295,339],"fungus,":[117],"House":[118],"Cricket,":[119],"Canola":[122],"tested":[125],"evaluate":[127,157],"IgE":[129],"cross-reactivity.":[130,146],"Whole":[131],"genome":[132],"sequencing,":[133],"genomic,":[134],"transcriptomic,":[135],"proteomic,":[136],"immunoinformatics":[138],"techniques":[139],"predict":[144],"Bioinformatics":[147],"helped":[149,289],"us":[150],"characterize":[152],"their":[153],"proteomes":[154],"critically":[156],"matches":[158,172],"putative":[160,174],"proven":[162],"allergens.":[163],"species":[167],"Fusarium":[169],"sp.":[170],"had":[171],"allergens,":[175],"which":[176],"extensively":[178],"conserved":[179],"allergenic,":[181],"non-allergenic":[183],"leading":[185],"need":[188],"critical":[190],"CODEX":[194],"guidelines.":[195],"Shrimp":[196],"allergic":[197,218],"patients":[198],"may":[199],"experience":[200],"cross-reactions":[201],"if":[202],"they":[203],"consume":[204],"crickets.":[205],"There":[206],"no":[208],"reason":[209],"suspect":[211],"that":[212],"canola":[215],"would":[216,221],"elicit":[217],"reactions":[219],"induce":[222],"toxic":[223],"responses.":[224],"addition,":[226],"we":[227,250],"sequence":[230],"searchable":[231],"celiac":[232],"database":[233],"identify":[235],"peptides":[236],"risk":[240],"assessment":[241],"food":[244],"proteins.":[245],"Concerning":[246],"studied":[251],"effect":[253],"nitrate":[256,287,331],"sulfate":[258,329],"finishing":[260],"cattle":[261],"performance":[262],"emissions.":[265],"address":[267],"16S":[270],"sequencing":[271],"metagenomics":[273],"were":[274],"better":[277],"understanding":[278],"rumen":[280],"composition":[282,308],"functionality.":[284],"Sulfate":[285],"combination":[288],"reduce":[291],"emissions,":[293],"with":[294,314,320],"reduction":[296,332],"average":[298],"daily":[299],"gain,":[300],"dry":[301],"matter":[302],"intake":[303],"gain:feed.":[305],"Ruminal":[306],"bacterial":[307],"illustrated":[309],"high":[310,321],"abundance":[311],"phyla":[313],"less":[315],"hydrogen":[316],"production,":[317],"genera":[319],"H2":[322],"utilization":[323],"capability":[324],"fatty":[326],"acids\u2019":[327],"formation,":[328],"instead":[333],"production.":[336],"Metagenomics":[337],"demonstrated":[338],"significant":[340],"decrease":[341],"enzymes":[343],"linked":[344],"methanogenesis":[346],"COMBO":[348],"diet.":[349],"Advisor:":[350],"Rick":[351],"Goodman":[352]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2020-05-13T00:00:00"}