{"id":"https://openalex.org/W3018540801","doi":"https://doi.org/10.1097/01.aog.0000664504.35290.66","title":"Risk-Factor Based Lead Screening and Correlation With Blood and Bone Lead Levels in Pregnancy [27K]","display_name":"Risk-Factor Based Lead Screening and Correlation With Blood and Bone Lead Levels in Pregnancy [27K]","publication_year":2020,"publication_date":"2020-04-25","ids":{"openalex":"https://openalex.org/W3018540801","doi":"https://doi.org/10.1097/01.aog.0000664504.35290.66","mag":"3018540801"},"language":"en","primary_location":{"id":"doi:10.1097/01.aog.0000664504.35290.66","doi":"https://doi.org/10.1097/01.aog.0000664504.35290.66","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.aog.0000664504.35290.66","pdf_url":null,"source":{"id":"https://openalex.org/S139838620","display_name":"Obstetrics and Gynecology","issn_l":"0029-7844","issn":["0029-7844","1873-233X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics & Gynecology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026461009","display_name":"Katherine M. Johnson","orcid":"https://orcid.org/0000-0002-5127-8139","observed_orcids":["https://orcid.org/0000-0002-5127-8139"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine Johnson","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002881187","display_name":"Aaron James Specht","orcid":"https://orcid.org/0000-0002-3342-1229","observed_orcids":["https://orcid.org/0000-0002-3342-1229"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron Specht","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103900321","display_name":"Saira Salahuddin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saira Salahuddin","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091270761","display_name":"Adrienne L. Erlinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adrienne L. Erlinger","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057970778","display_name":"Blair Johnson Wylie","orcid":"https://orcid.org/0000-0003-4818-1050","observed_orcids":["https://orcid.org/0000-0003-4818-1050"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Blair Wylie","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066406781","display_name":"Karen O\u2019Brien","orcid":"https://orcid.org/0000-0002-0158-0073","observed_orcids":["https://orcid.org/0000-0002-0158-0073"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen O'Brien","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA","institution_ids":["https://openalex.org/I1316535847"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1316535847"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.03241064,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"135","issue":"1","first_page":"120S","last_page":"121S"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10139","display_name":"Heavy metals in environment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10819","display_name":"Mercury impact and mitigation studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prenatal-lead-exposure","display_name":"prenatal lead exposure","score":0.8920000195503235},{"id":"https://openalex.org/keywords/lead-screening","display_name":"lead screening","score":0.7009999752044678},{"id":"https://openalex.org/keywords/risk-factor-based-screening","display_name":"risk factor-based screening","score":0.7990000247955322},{"id":"https://openalex.org/keywords/blood-lead-levels","display_name":"blood lead levels","score":0.7789999842643738},{"id":"https://openalex.org/keywords/bone-lead","display_name":"bone lead","score":0.9950000047683716},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.546999990940094},{"id":"https://openalex.org/keywords/parturients","display_name":"parturients","score":0.7269999980926514},{"id":"https://openalex.org/keywords/screening-test-sensitivity-and-specificity","display_name":"screening sensitivity and specificity","score":0.7329999804496765}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9527750015258789},{"id":"https://openalex.org/C2777093003","wikidata":"https://www.wikidata.org/wiki/Q6508345","display_name":"Lead (geology)","level":2,"score":0.7646503448486328},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6484115719795227},{"id":"https://openalex.org/C2776431099","wikidata":"https://www.wikidata.org/wiki/Q3392515","display_name":"Blood lead level","level":4,"score":0.6040009260177612},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5607779622077942},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.5297789573669434},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.413443386554718},{"id":"https://openalex.org/C3020026551","wikidata":"https://www.wikidata.org/wiki/Q110315","display_name":"Lead exposure","level":3,"score":0.3055093288421631},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2950071394443512},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.2854417860507965},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C114793014","wikidata":"https://www.wikidata.org/wiki/Q52109","display_name":"Geomorphology","level":1,"score":0.0},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0},{"id":"https://openalex.org/C2779904517","wikidata":"https://www.wikidata.org/wiki/Q5008900","display_name":"CATS","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/01.aog.0000664504.35290.66","doi":"https://doi.org/10.1097/01.aog.0000664504.35290.66","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.aog.0000664504.35290.66","pdf_url":null,"source":{"id":"https://openalex.org/S139838620","display_name":"Obstetrics and Gynecology","issn_l":"0029-7844","issn":["0029-7844","1873-233X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics & Gynecology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4206161079","https://openalex.org/W3112352898","https://openalex.org/W2337913550","https://openalex.org/W7140031549","https://openalex.org/W2036635279","https://openalex.org/W2005460223","https://openalex.org/W3206474455","https://openalex.org/W4407236242","https://openalex.org/W4414263578","https://openalex.org/W4390969290"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Lead":[1],"exposure":[2,231],"has":[3,41,246],"devastating":[4],"neurologic":[5],"consequences":[6],"for":[7,171,217,228],"children":[8],"and":[9,19,51,89,108,154,207,245],"may":[10],"begin":[11],"in":[12],"utero.":[13],"The":[14,35,115,146,192],"American":[15],"College":[16],"of":[17,38,49,66,125,138],"Obstetricians":[18],"Gynecologists":[20],"recommends":[21],"prenatal":[22,56],"lead":[23,53,86,91,104,111,129,144,149,157,218,230,236],"screening":[24],"using":[25,95,201],"a":[26,55,63,72,96,225],"risk":[27,57,134],"factor-based":[28],"approach":[29,40,227,240],"rather":[30],"than":[31],"universal":[32],"blood":[33,52,85,103,143,148,183,202],"testing.":[34,145],"clinical":[36,142],"utility":[37],"this":[39,239],"not":[42,165],"been":[43],"studied.":[44],"We":[45,61,83,100,121,131],"evaluated":[46],"the":[47,79,118,175,214],"association":[48],"bone":[50,90,110,156,166,190,208],"with":[54,71,234],"assessment":[58],"questionnaire.":[59],"METHODS:":[60],"enrolled":[62,122],"convenience":[64],"sample":[65],"parturients":[67,172,233],"\u226534":[68],"weeks\u2019":[69],"gestation,":[70],"singleton":[73],"pregnancy,":[74],"who":[75],"were":[76],"admitted":[77],"from":[78],"obstetrical":[80],"triage":[81],"unit.":[82],"measured":[84],"before":[87],"delivery":[88],"\u22644":[92],"days":[93],"postpartum":[94],"portable":[97],"X-ray":[98],"spectrometer.":[99],"defined":[101],"detectable":[102,109,182,189],"as":[105,112,213],"\u22652":[106],"ug/dL":[107,152],"\u226510":[113],"ug/g.":[114],"IRB":[116],"approved":[117],"study.":[119],"RESULTS:":[120],"102":[123],"participants,":[124],"whom":[126],"100":[127],"had":[128,141,181,188,194],"measured.":[130],"identified":[132],"\u22651":[133],"factor":[135],"among":[136],"78%":[137],"participants;":[139],"none":[140],"median":[147,155],"was":[150,158,168,241],"0.2":[151],"(0.2\u20130.4)":[153],"3.8":[159],"ug/g":[160],"(2.0\u20136.6).":[161],"Blood":[162],"lead,":[163,167,184],"but":[164,197,238],"significantly":[169],"higher":[170],"born":[173],"outside":[174],"US":[176],"(P=.01).":[177],"Two":[178],"participants":[179],"(2.2%)":[180],"while":[185],"16":[186],"(16.2%)":[187],"lead.":[191],"questionnaire":[193],"good":[195],"sensitivity":[196],"poor":[198,247],"specificity":[199,205,211],"when":[200],"(sensitivity":[203,209],"100%,":[204],"22%),":[206],"94%,":[210],"25%)":[212],"gold":[215],"standard":[216],"exposure.":[219],"CONCLUSION:":[220],"This":[221],"study":[222],"showed":[223],"that":[224],"risk-based":[226],"detecting":[229],"identifies":[232],"high":[235],"levels,":[237],"infrequently":[242],"used":[243],"clinically":[244],"specificity.":[248]},"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2020-05-01T00:00:00"}