{"id":"https://openalex.org/W3016845765","doi":"https://doi.org/10.1002/star.201900307","title":"Tailoring of Colon Targeting with Sodium Alginate\u2010Assam Bora Rice Starch Based Multi Particulate System Containing Naproxen","display_name":"Tailoring of Colon Targeting with Sodium Alginate\u2010Assam Bora Rice Starch Based Multi Particulate System Containing Naproxen","publication_year":2020,"publication_date":"2020-04-14","ids":{"openalex":"https://openalex.org/W3016845765","doi":"https://doi.org/10.1002/star.201900307","mag":"3016845765"},"language":"en","primary_location":{"id":"doi:10.1002/star.201900307","doi":"https://doi.org/10.1002/star.201900307","is_oa":false,"landing_page_url":"https://doi.org/10.1002/star.201900307","pdf_url":null,"source":{"id":"https://openalex.org/S55067746","display_name":"Starch - St\u00e4rke","issn_l":"0038-9056","issn":["0038-9056","1521-379X","2192-4236"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Starch - St\u00e4rke","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052774924","display_name":"Manoj Kumar Sarangi","orcid":"https://orcid.org/0000-0003-4539-5213","observed_orcids":["https://orcid.org/0000-0003-4539-5213"]},"institutions":[{"id":"https://openalex.org/I4028839","display_name":"Biju Patnaik University of Technology","ror":"https://ror.org/03vqjtg68","country_code":"IN","type":"education","lineage":["https://openalex.org/I4028839"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Manoj Kumar Sarangi","raw_affiliation_strings":["Ph.D. Research Scholar, Bijupatnaik University of Technology, Rourkela, Odisha, 769004 India","Sardar Bhagwan Singh Postgraduate Institute of Biomedical Sciences and Research, Balawala, Dehradun, Uttarakhand, 248001 India"],"raw_orcid":"https://orcid.org/0000-0003-4539-5213","affiliations":[{"raw_affiliation_string":"Ph.D. Research Scholar, Bijupatnaik University of Technology, Rourkela, Odisha, 769004 India","institution_ids":["https://openalex.org/I4028839"]},{"raw_affiliation_string":"Sardar Bhagwan Singh Postgraduate Institute of Biomedical Sciences and Research, Balawala, Dehradun, Uttarakhand, 248001 India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112858082","display_name":"Muddana Eswara Bhanoji Rao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099853","display_name":"Roland Institute of Pharmaceutical Sciences","ror":"https://ror.org/01vva4430","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210099853"]},{"id":"https://openalex.org/I4405283056","display_name":"Calcutta Institute of Pharmaceutical Technology & Allied Health Sciences","ror":"https://ror.org/00xs8fr58","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405283056"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"M.E. Bhanoji Rao","raw_affiliation_strings":["Calcutta Institute of Pharmaceutical Technology & Allied Health sciences Howrah West Bengal 711316 India","Roland Institute of Pharmaceutical Sciences, Berhampur, Odisha, 760010 India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Calcutta Institute of Pharmaceutical Technology & Allied Health sciences Howrah West Bengal 711316 India","institution_ids":["https://openalex.org/I4405283056"]},{"raw_affiliation_string":"Roland Institute of Pharmaceutical Sciences, Berhampur, Odisha, 760010 India","institution_ids":["https://openalex.org/I4210099853"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060209909","display_name":"Versha Parcha","orcid":"https://orcid.org/0000-0003-0202-1625","observed_orcids":["https://orcid.org/0000-0003-0202-1625"]},"institutions":[{"id":"https://openalex.org/I4210138733","display_name":"Dolphin (PG) Institute of Bio Medical and Natural Science","ror":"https://ror.org/04phk2284","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210138733"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Versha Parcha","raw_affiliation_strings":["Dolphin (PG) Institute of Biomedical & Natural Sciences Dehradun Uttarakhand 248007 India","Sardar Bhagwan Singh Postgraduate Institute of Biomedical Sciences and Research, Balawala, Dehradun, Uttarakhand, 248001 India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dolphin (PG) Institute of Biomedical & Natural Sciences Dehradun Uttarakhand 248007 India","institution_ids":["https://openalex.org/I4210138733"]},{"raw_affiliation_string":"Sardar Bhagwan Singh Postgraduate Institute of Biomedical Sciences and Research, Balawala, Dehradun, Uttarakhand, 248001 India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109456112","display_name":"Aadesh Upadhyay","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aadesh Upadhyay","raw_affiliation_strings":["Sardar Bhagwan Singh Postgraduate Institute of Biomedical Sciences and Research, Balawala, Dehradun, Uttarakhand, 248001 India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sardar Bhagwan Singh Postgraduate Institute of Biomedical Sciences and Research, Balawala, Dehradun, Uttarakhand, 248001 India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5052774924"],"corresponding_institution_ids":["https://openalex.org/I4028839"],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":null,"fwci":0.4892,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.50780966,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"72","issue":"7-8","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.012900000438094139,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12048","display_name":"Microencapsulation and Drying Processes","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colon-targeting","display_name":"colon targeting","score":0.8029999732971191},{"id":"https://openalex.org/keywords/sodium-alginate","display_name":"sodium alginate","score":0.9340000152587891},{"id":"https://openalex.org/keywords/naproxen","display_name":"naproxen","score":0.9580000042915344},{"id":"https://openalex.org/keywords/ionic-gelation","display_name":"ionic gelation","score":0.972000002861023},{"id":"https://openalex.org/keywords/eudragit-s100-coating","display_name":"Eudragit S100 coating","score":0.9169999957084656},{"id":"https://openalex.org/keywords/encapsulation-efficiency","display_name":"encapsulation efficiency","score":0.875},{"id":"https://openalex.org/keywords/in-vitro-drug-release","display_name":"in vitro drug release","score":0.8849999904632568},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.7289999723434448},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.9639999866485596},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.9900000095367432}],"concepts":[{"id":"https://openalex.org/C2778115740","wikidata":"https://www.wikidata.org/wiki/Q1215575","display_name":"Naproxen","level":3,"score":0.7317836284637451},{"id":"https://openalex.org/C529335014","wikidata":"https://www.wikidata.org/wiki/Q41534","display_name":"Starch","level":2,"score":0.6549091339111328},{"id":"https://openalex.org/C2992618853","wikidata":"https://www.wikidata.org/wiki/Q422092","display_name":"Sodium alginate","level":3,"score":0.6116456985473633},{"id":"https://openalex.org/C24245907","wikidata":"https://www.wikidata.org/wiki/Q498957","display_name":"Particulates","level":2,"score":0.48034584522247314},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.44652512669563293},{"id":"https://openalex.org/C2776633847","wikidata":"https://www.wikidata.org/wiki/Q574416","display_name":"Resistant starch","level":3,"score":0.43326476216316223},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.3940490782260895},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38654816150665283},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20801612734794617},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.07007691264152527},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.04646751284599304},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/star.201900307","doi":"https://doi.org/10.1002/star.201900307","is_oa":false,"landing_page_url":"https://doi.org/10.1002/star.201900307","pdf_url":null,"source":{"id":"https://openalex.org/S55067746","display_name":"Starch - St\u00e4rke","issn_l":"0038-9056","issn":["0038-9056","1521-379X","2192-4236"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Starch - St\u00e4rke","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W12880965","https://openalex.org/W1965688885","https://openalex.org/W1973482358","https://openalex.org/W1977072597","https://openalex.org/W1982733518","https://openalex.org/W1985981088","https://openalex.org/W1989024479","https://openalex.org/W1989157106","https://openalex.org/W1991092566","https://openalex.org/W1995263937","https://openalex.org/W2004994165","https://openalex.org/W2013716578","https://openalex.org/W2014036762","https://openalex.org/W2025282728","https://openalex.org/W2028400301","https://openalex.org/W2029103483","https://openalex.org/W2030694746","https://openalex.org/W2032634456","https://openalex.org/W2035553618","https://openalex.org/W2039934416","https://openalex.org/W2050145778","https://openalex.org/W2054992440","https://openalex.org/W2056952605","https://openalex.org/W2058469185","https://openalex.org/W2069455532","https://openalex.org/W2072624182","https://openalex.org/W2075895322","https://openalex.org/W2076603604","https://openalex.org/W2078785621","https://openalex.org/W2089430865","https://openalex.org/W2102372561","https://openalex.org/W2132545697","https://openalex.org/W2158539197","https://openalex.org/W2161234981","https://openalex.org/W2170654777","https://openalex.org/W2171419688","https://openalex.org/W2317856560","https://openalex.org/W2329548797","https://openalex.org/W2502085939","https://openalex.org/W2756539297","https://openalex.org/W2766975701","https://openalex.org/W2776538941","https://openalex.org/W2884583604","https://openalex.org/W2915532549","https://openalex.org/W2962130039"],"related_works":["https://openalex.org/W1810212338","https://openalex.org/W2258939324","https://openalex.org/W2277681690","https://openalex.org/W2937857011","https://openalex.org/W2109659597","https://openalex.org/W2882997303","https://openalex.org/W4411327140","https://openalex.org/W2972766694","https://openalex.org/W4409196574","https://openalex.org/W4377209567"],"abstract_inverted_index":{"Abstract":[0],"This":[1],"research":[2],"is":[3,83,93,145],"focused":[4],"on":[5,61,169,182],"the":[6,62,77,90,142,150,185,189],"formulation":[7],"and":[8,46,59,71,100,127],"optimization":[9],"of":[10,51,55,88,108,117,141,152,188],"Assam":[11],"Bora":[12],"rice":[13],"starch":[14],"(ABRS)\u2010alginate":[15],"beads":[16,92,118,144,158,190],"containing":[17,159],"a":[18,52,135,166,174],"non\u2010steroidal":[19],"anti\u2010inflammatory":[20],"drug":[21,63,74,106,163],"(NSAID)":[22],"such":[23],"as":[24],"Naproxen":[25],"(NA),":[26],"by":[27],"an":[28,103],"ionotropic":[29],"gelation":[30],"technique":[31],"using":[32],"3":[33],"2":[34],"factorial":[35],"design":[36],"for":[37],"colon":[38,47,132,186],"targeting":[39,133,187],"against":[40],"rheumatoid":[41],"arthritis,":[42],"inflammatory":[43],"bowel":[44],"disease,":[45],"cancer.":[48],"The":[49,85,114,138,155,177],"impact":[50],"polymeric":[53],"blend":[54],"sodium":[56],"alginate":[57],"(SA)":[58],"ABRS":[60],"entrapment":[64],"efficiency":[65],"(DEE,":[66],"%),":[67],"bead":[68],"size":[69,140],"(BS),":[70],"percentage":[72],"cumulative":[73],"release":[75,107],"in":[76,97,104,110,134,178],"first":[78,111],"6":[79,112],"h":[80],"(Q6,":[81],"%)":[82],"optimized.":[84],"DEE":[86],"(%)":[87],"all":[89],"developed":[91,143],"found":[94,146],"to":[95,130,147],"be":[96,148],"between":[98],"45.25%":[99],"85.14%":[101],"with":[102,121],"vitro":[105],"32.81\u201342.18%":[109],"h.":[113],"optimized":[115,156],"batches":[116],"are":[119],"coated":[120],"Eudragit":[122],"S100":[123],"(ES100)":[124],"(5%,":[125],"10%,":[126],"15%":[128],"w/v)":[129],"facilitate":[131],"prominent":[136],"way.":[137],"average":[139],"within":[149],"range":[151],"751.61\u2013822.22":[153],"\u00b5m.":[154],"ABRS\u2010alginate":[157],"NA":[160],"show":[161],"significant":[162],"permeability":[164,172],"over":[165],"prolonged":[167],"period":[168],"ex":[170],"vivo":[171,179],"through":[173],"goat":[175],"colon.":[176],"roentgenographic":[180],"study":[181],"rats":[183],"shows":[184],"without":[191],"degradation.":[192]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-04-24T00:00:00"}