{"id":"https://openalex.org/W3016631473","doi":"https://doi.org/10.7759/cureus.7682","title":"The Effect of High Velocity Low Amplitude Cervical Manipulations on the Musculoskeletal System: Literature Review","display_name":"The Effect of High Velocity Low Amplitude Cervical Manipulations on the Musculoskeletal System: Literature Review","publication_year":2020,"publication_date":"2020-04-15","ids":{"openalex":"https://openalex.org/W3016631473","doi":"https://doi.org/10.7759/cureus.7682","mag":"3016631473","pmid":"https://pubmed.ncbi.nlm.nih.gov/32426194","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7228797"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.7682","doi":"https://doi.org/10.7759/cureus.7682","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.7682","pdf_url":"https://www.cureus.com/articles/29686-the-effect-of-high-velocity-low-amplitude-cervical-manipulations-on-the-musculoskeletal-system-literature-review.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cureus.com/articles/29686-the-effect-of-high-velocity-low-amplitude-cervical-manipulations-on-the-musculoskeletal-system-literature-review.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010864905","display_name":"Andrea Giacalone","orcid":"https://orcid.org/0000-0002-4779-0340","observed_orcids":["https://orcid.org/0000-0002-4779-0340"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]},{"id":"https://openalex.org/I4405261151","display_name":"Aeronautica Militare","ror":"https://ror.org/04w9m1f21","country_code":"IT","type":"government","lineage":["https://openalex.org/I4210114321","https://openalex.org/I4405261151"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Andrea Giacalone","raw_affiliation_strings":["Industrial Engineering Technologies for Sports Medicine and Rehabilitation, University of Rome Tor Vergata, Rome, ITA",". Aerospace Medicine, Diagnostic Therapeutic and Rehabilitative Aeromedical Center, Italian Air Force, Rome, ITA",". Neurology, Sapienza University, Rome, ITA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Industrial Engineering Technologies for Sports Medicine and Rehabilitation, University of Rome Tor Vergata, Rome, ITA","institution_ids":["https://openalex.org/I116067653"]},{"raw_affiliation_string":". Aerospace Medicine, Diagnostic Therapeutic and Rehabilitative Aeromedical Center, Italian Air Force, Rome, ITA","institution_ids":["https://openalex.org/I4405261151"]},{"raw_affiliation_string":". Neurology, Sapienza University, Rome, ITA","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084371551","display_name":"Massimiliano Febbi","orcid":"https://orcid.org/0000-0003-1091-997X","observed_orcids":["https://orcid.org/0000-0003-1091-997X"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]},{"id":"https://openalex.org/I4405261151","display_name":"Aeronautica Militare","ror":"https://ror.org/04w9m1f21","country_code":"IT","type":"government","lineage":["https://openalex.org/I4210114321","https://openalex.org/I4405261151"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimiliano Febbi","raw_affiliation_strings":["Industrial Engineering Technologies for Sports Medicine and Rehabilitation, University of Rome Tor Vergata, Rome, ITA",". Aerospace Medicine, Diagnostic Therapeutic and Rehabilitative Aeromedical Center, Italian Air Force, Rome, ITA",". Neurology, Sapienza University, Rome, ITA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Industrial Engineering Technologies for Sports Medicine and Rehabilitation, University of Rome Tor Vergata, Rome, ITA","institution_ids":["https://openalex.org/I116067653"]},{"raw_affiliation_string":". Aerospace Medicine, Diagnostic Therapeutic and Rehabilitative Aeromedical Center, Italian Air Force, Rome, ITA","institution_ids":["https://openalex.org/I4405261151"]},{"raw_affiliation_string":". Neurology, Sapienza University, Rome, ITA","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061149035","display_name":"Fabrizio Magnifica","orcid":"https://orcid.org/0000-0002-8802-5477","observed_orcids":["https://orcid.org/0000-0002-8802-5477"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]},{"id":"https://openalex.org/I4405261151","display_name":"Aeronautica Militare","ror":"https://ror.org/04w9m1f21","country_code":"IT","type":"government","lineage":["https://openalex.org/I4210114321","https://openalex.org/I4405261151"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fabrizio Magnifica","raw_affiliation_strings":["Aerospace Medicine, Diagnostic Therapeutic and Rehabilitative Aeromedical Center, Italian Air Force, Rome, ITA","Neurology, Sapienza University, Rome, ITA",". Industrial Engineering Technologies for Sports Medicine and Rehabilitation, University of Rome Tor Vergata, Rome, ITA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aerospace Medicine, Diagnostic Therapeutic and Rehabilitative Aeromedical Center, Italian Air Force, Rome, ITA","institution_ids":["https://openalex.org/I4405261151"]},{"raw_affiliation_string":"Neurology, Sapienza University, Rome, ITA","institution_ids":["https://openalex.org/I861853513"]},{"raw_affiliation_string":". Industrial Engineering Technologies for Sports Medicine and Rehabilitation, University of Rome Tor Vergata, Rome, ITA","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035057244","display_name":"Enzo Ruberti","orcid":"https://orcid.org/0000-0002-1609-5492","observed_orcids":["https://orcid.org/0000-0002-1609-5492"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]},{"id":"https://openalex.org/I4405261151","display_name":"Aeronautica Militare","ror":"https://ror.org/04w9m1f21","country_code":"IT","type":"government","lineage":["https://openalex.org/I4210114321","https://openalex.org/I4405261151"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Enzo Ruberti","raw_affiliation_strings":["Neurology, Sapienza University, Rome, ITA",". Aerospace Medicine, Diagnostic Therapeutic and Rehabilitative Aeromedical Center, Italian Air Force, Rome, ITA",". Industrial Engineering Technologies for Sports Medicine and Rehabilitation, University of Rome Tor Vergata, Rome, ITA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology, Sapienza University, Rome, ITA","institution_ids":["https://openalex.org/I861853513"]},{"raw_affiliation_string":". Aerospace Medicine, Diagnostic Therapeutic and Rehabilitative Aeromedical Center, Italian Air Force, Rome, ITA","institution_ids":["https://openalex.org/I4405261151"]},{"raw_affiliation_string":". Industrial Engineering Technologies for Sports Medicine and Rehabilitation, University of Rome Tor Vergata, Rome, ITA","institution_ids":["https://openalex.org/I116067653"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5010864905"],"corresponding_institution_ids":["https://openalex.org/I116067653","https://openalex.org/I4405261151","https://openalex.org/I861853513"],"apc_list":null,"apc_paid":null,"fwci":1.0485,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.68892045,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":"4","first_page":"e7682","last_page":"e7682"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12712","display_name":"Myofascial pain diagnosis and treatment","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13946","display_name":"Musculoskeletal Disorders and Rehabilitation","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-velocity-low-amplitude-manipulation","display_name":"high-velocity low-amplitude manipulation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/cervical-spine-manipulation","display_name":"cervical manipulation","score":0.9539999961853027},{"id":"https://openalex.org/keywords/thrust-manipulation","display_name":"thrust manipulation","score":0.875},{"id":"https://openalex.org/keywords/cervical-spine","display_name":"cervical spine","score":0.7749999761581421},{"id":"https://openalex.org/keywords/musculoskeletal-disorders","display_name":"musculoskeletal disorders","score":0.9300000071525574},{"id":"https://openalex.org/keywords/neck-pain","display_name":"neck pain","score":0.8970000147819519},{"id":"https://openalex.org/keywords/epicondylitis","display_name":"epicondylitis","score":0.9769999980926514},{"id":"https://openalex.org/keywords/temporomandibular-disorders","display_name":"temporomandibular disorders","score":0.9929999709129333},{"id":"https://openalex.org/keywords/shoulder-pain","display_name":"shoulder pain","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pain-modulation","display_name":"pain modulation","score":0.9539999961853027},{"id":"https://openalex.org/keywords/mobility-physical-function","display_name":"mobility (physical function)","score":0.6480000019073486},{"id":"https://openalex.org/keywords/muscle-strength","display_name":"muscle strength","score":0.9559999704360962},{"id":"https://openalex.org/keywords/manual-therapy","display_name":"manual therapy","score":0.8330000042915344}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9353553056716919},{"id":"https://openalex.org/C514863369","wikidata":"https://www.wikidata.org/wiki/Q1427967","display_name":"Manual therapy","level":3,"score":0.781232476234436},{"id":"https://openalex.org/C2779470654","wikidata":"https://www.wikidata.org/wiki/Q1074773","display_name":"Spinal manipulation","level":4,"score":0.7706171870231628},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.6868703365325928},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6548561453819275},{"id":"https://openalex.org/C2985379065","wikidata":"https://www.wikidata.org/wiki/Q900457","display_name":"Cervical spine","level":2,"score":0.5305103659629822},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.518803060054779},{"id":"https://openalex.org/C2780907711","wikidata":"https://www.wikidata.org/wiki/Q852163","display_name":"Low back pain","level":3,"score":0.41945984959602356},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.21927368640899658},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.1375625729560852},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.7759/cureus.7682","doi":"https://doi.org/10.7759/cureus.7682","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.7682","pdf_url":"https://www.cureus.com/articles/29686-the-effect-of-high-velocity-low-amplitude-cervical-manipulations-on-the-musculoskeletal-system-literature-review.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmid:32426194","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32426194","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7228797","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7228797/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Text"},{"id":"pmh:oai:iris.uniroma1.it:11573/1437010","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11573/1437010","pdf_url":"https://iris.uniroma1.it/bitstream/11573/1437010/1/Giacalone_The%20Effect%20of%20High%20Velocity_2020.pdf","source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.7759/cureus.7682","doi":"https://doi.org/10.7759/cureus.7682","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.7682","pdf_url":"https://www.cureus.com/articles/29686-the-effect-of-high-velocity-low-amplitude-cervical-manipulations-on-the-musculoskeletal-system-literature-review.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3016631473.pdf","grobid_xml":"https://content.openalex.org/works/W3016631473.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1589269664","https://openalex.org/W1969108437","https://openalex.org/W1973323854","https://openalex.org/W1993812500","https://openalex.org/W1998281398","https://openalex.org/W2005434961","https://openalex.org/W2007701602","https://openalex.org/W2008058736","https://openalex.org/W2014742842","https://openalex.org/W2016807223","https://openalex.org/W2017429007","https://openalex.org/W2036520901","https://openalex.org/W2051511687","https://openalex.org/W2053357901","https://openalex.org/W2058503245","https://openalex.org/W2085175333","https://openalex.org/W2085245434","https://openalex.org/W2087786963","https://openalex.org/W2088458786","https://openalex.org/W2097113226","https://openalex.org/W2107115130","https://openalex.org/W2135456462","https://openalex.org/W2143234505","https://openalex.org/W2160888194","https://openalex.org/W2167810128","https://openalex.org/W2402690341","https://openalex.org/W2509297803","https://openalex.org/W2542161862","https://openalex.org/W2564238194","https://openalex.org/W2751884637","https://openalex.org/W2788588408","https://openalex.org/W2901128588","https://openalex.org/W2909422183","https://openalex.org/W3021328258","https://openalex.org/W3088169262"],"related_works":["https://openalex.org/W4413164368","https://openalex.org/W2738672531","https://openalex.org/W2558258551","https://openalex.org/W4412493994","https://openalex.org/W1998281398","https://openalex.org/W2099733189","https://openalex.org/W1427680015","https://openalex.org/W4310515045","https://openalex.org/W1979580317","https://openalex.org/W4412099776"],"abstract_inverted_index":{"In":[0,284],"manual":[1],"therapy,":[2],"high":[3],"velocity":[4],"low":[5,276],"amplitude":[6],"(HVLA)":[7],"cervical":[8,70,148],"manipulation":[9,71,142,236,264,270],"techniques":[10,30,271],"are":[11,25,31,182,202,265,299],"frequently":[12],"used,":[13],"but":[14,41,256],"often":[15],"the":[16,35,47,64,85,90,101,105,110,113,147,153,165,171,193,225,229,249,257,269,280,286,295],"physiological":[17],"and":[18,162,189,196,212,294],"biomechanical":[19,38],"effects":[20],"that":[21,174,235],"can":[22,72,237,244],"be":[23,273,292],"obtained":[24],"not":[26,254],"completely":[27],"clear.":[28],"The":[29,61,115,137,168],"mostly":[32],"used":[33],"for":[34,248],"treatment":[36],"of":[37,49,63,92,112,130,156,170,206,228,259,282,289],"joint":[39,210],"dysfunction,":[40],"little":[42],"is":[43,66],"yet":[44,233],"known":[45],"about":[46],"possibility":[48],"using":[50],"them":[51],"in":[52,125,192,204,221],"order":[53],"to":[54,67,94,108,135,164,184,217,262,291],"achieve":[55],"better":[56],"performance":[57],"on":[58,74,84,177,219],"healthy":[59,222],"subjects.":[60],"objective":[62],"study":[65],"describe":[68],"how":[69],"impact":[73],"a":[75,198],"musculoskeletal":[76,180],"disorder.":[77],"A":[78],"systematic":[79],"search":[80],"was":[81,140],"carried":[82],"out":[83],"Pubmed":[86],"electronic":[87],"database":[88],"from":[89,133],"beginning":[91],"January":[93],"March":[95],"2020.":[96,136],"Two":[97],"independent":[98],"reviewers":[99],"conducted":[100],"screening":[102],"process":[103],"through":[104],"PRISMA":[106],"diagram":[107],"determine":[109],"eligibility":[111],"articles.":[114],"inclusion":[116],"criteria":[117],"covered":[118],"randomized":[119],"controlled":[120],"trial":[121],"(RCT)":[122],"manuscripts":[123],"published":[124],"peer-reviewed":[126],"journals":[127],"with":[128,179],"individuals":[129],"all":[131],"ages":[132],"2005":[134],"included":[138],"intervention":[139],"thrust":[141],"or":[143,279],"HVLA":[144,175],"directed":[145],"towards":[146],"spine":[149],"region.":[150],"After":[151],"reviewing":[152],"literature,":[154],"21":[155],"74":[157],"articles":[158],"were":[159],"considered":[160],"useful":[161],"relevant":[163],"research":[166,172],"question.":[167],"results":[169,218],"show":[173],"techniques,":[176],"subjects":[178],"disorders,":[181],"able":[183],"influence":[185,239],"pain":[186],"modulation,":[187],"mobility":[188],"strength":[190,220],"both":[191],"treated":[194],"area":[195],"at":[197],"distance.":[199],"Cervical":[200,242],"manipulations":[201,243,290],"effective":[203],"management":[205],"cervicalgia,":[207],"epicondylalgia,":[208],"temporomandibular":[209],"disorders":[211],"shoulder":[213],"pain.":[214],"With":[215],"regard":[216],"subjects,":[223],"given":[224],"divergent":[226],"opinions":[227],"authors,":[230],"we":[231],"cannot":[232],"state":[234],"significantly":[238],"this":[240],"parameter.":[241],"also":[245],"have":[246],"risks":[247],"patient":[250],"if":[251],"applied":[252],"when":[253],"appropriate":[255],"frequency":[258],"complications":[260],"due":[261],"vertebral":[263],"very":[266],"low.":[267],"However,":[268],"might":[272],"limited":[274],"by":[275],"patients":[277],"tolerance":[278],"presence":[281],"contraindications.":[283],"addition,":[285],"optimal":[287],"number":[288],"performed":[293],"long-term":[296],"benefits":[297],"produced":[298],"unknown.":[300]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":4},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2020-04-24T00:00:00"}