{"id":"https://openalex.org/W3016570544","doi":"https://doi.org/10.1096/fasebj.2020.34.s1.03516","title":"Sex differences in the evolution of net respiratory muscle pressures during incremental exercise","display_name":"Sex differences in the evolution of net respiratory muscle pressures during incremental exercise","publication_year":2020,"publication_date":"2020-04-01","ids":{"openalex":"https://openalex.org/W3016570544","doi":"https://doi.org/10.1096/fasebj.2020.34.s1.03516","mag":"3016570544"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.2020.34.s1.03516","doi":"https://doi.org/10.1096/fasebj.2020.34.s1.03516","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.2020.34.s1.03516","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10072/414125","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060798384","display_name":"Troy James Cross","orcid":"https://orcid.org/0000-0003-2902-7787","observed_orcids":["https://orcid.org/0000-0003-2902-7787"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Troy James Cross","raw_affiliation_strings":["Mayo Clinic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013670071","display_name":"Catherine L. Coriell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203172682","display_name":"Northern Arizona University","ror":"https://ror.org/0272j5188","country_code":"US","type":"education","lineage":["https://openalex.org/I203172682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine L. Coriell","raw_affiliation_strings":["Northern Arizona University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northern Arizona University","institution_ids":["https://openalex.org/I203172682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070996405","display_name":"Elizabeth A. Gideon","orcid":"https://orcid.org/0009-0002-6877-681X","observed_orcids":["https://orcid.org/0009-0002-6877-681X"]},"institutions":[{"id":"https://openalex.org/I203172682","display_name":"Northern Arizona University","ror":"https://ror.org/0272j5188","country_code":"US","type":"education","lineage":["https://openalex.org/I203172682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth A. Gideon","raw_affiliation_strings":["Northern Arizona University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northern Arizona University","institution_ids":["https://openalex.org/I203172682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050469153","display_name":"Aaron W. Betts","orcid":"https://orcid.org/0009-0005-4571-3818","observed_orcids":["https://orcid.org/0009-0005-4571-3818"]},"institutions":[{"id":"https://openalex.org/I203172682","display_name":"Northern Arizona University","ror":"https://ror.org/0272j5188","country_code":"US","type":"education","lineage":["https://openalex.org/I203172682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron W. Betts","raw_affiliation_strings":["Northern Arizona University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northern Arizona University","institution_ids":["https://openalex.org/I203172682"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088401451","display_name":"Joseph W. Duke","orcid":"https://orcid.org/0000-0001-5542-5581","observed_orcids":["https://orcid.org/0000-0001-5542-5581"]},"institutions":[{"id":"https://openalex.org/I203172682","display_name":"Northern Arizona University","ror":"https://ror.org/0272j5188","country_code":"US","type":"education","lineage":["https://openalex.org/I203172682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph W. Duke","raw_affiliation_strings":["Northern Arizona University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northern Arizona University","institution_ids":["https://openalex.org/I203172682"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2500,"currency":"USD","value_usd":2500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04345856,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"34","issue":"S1","first_page":"1","last_page":"1"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.0568000003695488,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.009399999864399433,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8709999918937683},{"id":"https://openalex.org/keywords/respiratory-muscle-pressure","display_name":"respiratory muscle pressure","score":0.9700000286102295},{"id":"https://openalex.org/keywords/work-of-breathing","display_name":"work of breathing","score":0.7310000061988831},{"id":"https://openalex.org/keywords/incremental-exercise","display_name":"incremental exercise","score":0.6850000023841858},{"id":"https://openalex.org/keywords/cycling","display_name":"cycling","score":0.7099999785423279},{"id":"https://openalex.org/keywords/pleural-pressure","display_name":"pleural pressure","score":0.753000020980835},{"id":"https://openalex.org/keywords/esophageal-balloon-catheter","display_name":"esophageal balloon catheter","score":0.8949999809265137},{"id":"https://openalex.org/keywords/minute-ventilation","display_name":"minute ventilation","score":0.7310000061988831},{"id":"https://openalex.org/keywords/respiratory-motor-output","display_name":"respiratory motor output","score":0.6930000185966492},{"id":"https://openalex.org/keywords/respiratory-muscle-fatigue","display_name":"respiratory muscle fatigue","score":0.34700000286102295},{"id":"https://openalex.org/keywords/respiratory-muscle-endurance","display_name":"respiratory muscle endurance","score":0.5360000133514404},{"id":"https://openalex.org/keywords/respiratory-muscle-strength","display_name":"respiratory muscle strength","score":0.41600000858306885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7458368539810181},{"id":"https://openalex.org/C2776924770","wikidata":"https://www.wikidata.org/wiki/Q23808249","display_name":"Work of breathing","level":3,"score":0.67205810546875},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.5837336778640747},{"id":"https://openalex.org/C2776164194","wikidata":"https://www.wikidata.org/wiki/Q2501440","display_name":"Expiration","level":3,"score":0.5626890659332275},{"id":"https://openalex.org/C43396882","wikidata":"https://www.wikidata.org/wiki/Q2197000","display_name":"Exhalation","level":2,"score":0.5173851251602173},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5022826194763184},{"id":"https://openalex.org/C2778856057","wikidata":"https://www.wikidata.org/wiki/Q6015458","display_name":"Incremental exercise","level":4,"score":0.4753655791282654},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.4618951082229614},{"id":"https://openalex.org/C2777473361","wikidata":"https://www.wikidata.org/wiki/Q5353564","display_name":"Elastic recoil","level":3,"score":0.45236843824386597},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.4458591341972351},{"id":"https://openalex.org/C8213797","wikidata":"https://www.wikidata.org/wiki/Q754250","display_name":"Respiratory rate","level":4,"score":0.4216099679470062},{"id":"https://openalex.org/C79959777","wikidata":"https://www.wikidata.org/wiki/Q754333","display_name":"Respiratory minute volume","level":3,"score":0.41387826204299927},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.367966890335083},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3607029914855957},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.2590871751308441},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.24758285284042358},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.22796830534934998},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1096/fasebj.2020.34.s1.03516","doi":"https://doi.org/10.1096/fasebj.2020.34.s1.03516","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.2020.34.s1.03516","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},{"id":"pmh:oai:research-repository.griffith.edu.au:10072/414125","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10072/414125","pdf_url":null,"source":{"id":"https://openalex.org/S7407064376","display_name":"Griffith Research Online","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Conference output"}],"best_oa_location":{"id":"pmh:oai:research-repository.griffith.edu.au:10072/414125","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10072/414125","pdf_url":null,"source":{"id":"https://openalex.org/S7407064376","display_name":"Griffith Research Online","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Conference output"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3167313338","https://openalex.org/W4402661958","https://openalex.org/W2889832545","https://openalex.org/W4294818074","https://openalex.org/W2119133992","https://openalex.org/W2994412204","https://openalex.org/W4243489484","https://openalex.org/W2128063107","https://openalex.org/W2290976844","https://openalex.org/W3203416496"],"abstract_inverted_index":{"The":[0,203,291,325,390],"respiratory":[1,81,401],"muscle":[2,18,56,402],"pressure":[3,239,253],"(P":[4,240,254],"mus":[5,42,126,141,159,268,282,295,320,333,419],")":[6],"waveform":[7,43,142],"lends":[8],"insight":[9],"into":[10],"the":[11,40,66,93,117,122,139,152,197,223,276,355,398,467,479],"patterns":[12],"of":[13,24,39,68,80,95,124,138,154,328,357,363,393,400,424,481],"net":[14,425],"inspiratory":[15,53,70,155,293,417,426],"v":[16],"expiratory":[17,55,157,318,364,428],"recruitment":[19,57,403],"under":[20],"a":[21,106,135,305,346,361],"wide":[22],"variety":[23],"conditions,":[25],"including":[26],"mechanical":[27],"ventilation,":[28],"spontaneous":[29],"breathing,":[30],"and":[31,46,54,64,156,162,181,212,387,421],"during":[32,44,110,132,143,164,275,309,334,372,408,478],"exercise.":[33,111,133],"On":[34,222],"this":[35,394,482],"last":[36],"point,":[37],"inspection":[38],"P":[41,125,140,158,267,281,284,287,294,313,319,332,351,375,418],"incremental":[45,165,261,310,409],"constant":[47],"work":[48,94],"rate":[49],"cycling":[50,262,311],"reveals":[51],"that":[52,65,92,397],"systematically":[58,98,415],"increase":[59],"with":[60,103,229,302,368,431],"rising":[61],"minute":[62,108,273,307,348,370],"ventilations,":[63],"duration":[67,356],"post\u2010inspiratory":[69],"activity":[71],"(PIIA)":[72],"gradually":[73,366],"disappears":[74],"from":[75],"low":[76],"to":[77,208,213,234,248],"high":[78],"levels":[79],"motor":[82],"output.":[83],"In":[84],"recent":[85],"years,":[86],"it":[87],"has":[88,115],"become":[89],"increasingly":[90],"evident":[91],"breathing":[96],"is":[97,147],"higher":[99],"for":[100,216,472],"women":[101,163,183,413],"compared":[102,301,430],"men":[104,161,169,303,386,432],"at":[105,271,304,345,433],"given":[107,272,306,347],"ventilation":[109,308,349,371],"Yet,":[112],"no":[113,437],"study":[114,395],"examined":[116],"potential":[118],"sex":[119],"differences":[120,438],"in":[121,237,299,331,341,380,439],"evolution":[123,153],"(and":[127],"its":[128],"components;":[129],"e.g.,":[130],"PIIA)":[131],"Thus,":[134],"comprehensive":[136],"assessment":[137],"exercise":[144,277,373],"between":[145,160,323,385,406,441],"sexes":[146,407,442],"warranted.":[148],"Purpose":[149],"To":[150],"compare":[151],"cycling.":[166],"Methods":[167],"Thirteen":[168],"(21":[170,184],"\u00b1":[171,174,178,185,189,193],"yrs;":[172,187],"181":[173],"5":[175],"cm;":[176,191],"82":[177],"11":[179],"kg)":[180,195],"10":[182],"1":[186],"165":[188],"6":[190,194],"62":[192],"visited":[196],"laboratory":[198],"on":[199],"two":[200],"separate":[201],"occasions.":[202],"first":[204],"occasion":[205],"was":[206,269,321,382,396,404,451,464],"used":[207],"obtain":[209],"informed":[210],"consent":[211],"screen":[214],"participants":[215,226],"normal":[217],"pulmonary":[218],"function":[219],"(>85%":[220],"age\u2010predicted).":[221],"second":[224],"visit,":[225],"were":[227,246,296,338,443],"instrumented":[228],"an":[230,260],"esophageal":[231],"balloon":[232],"catheter":[233],"estimate":[235],"variations":[236],"pleural":[238],"pl":[241,288],").":[242,256],"Quasi\u2010static":[243],"relaxation":[244],"curves":[245],"obtained":[247],"measure":[249],"chest":[250],"wall":[251],"recoil":[252],"cw":[255,285],"Participants":[257],"then":[258],"completed":[259],"protocol":[263,278],"until":[264],"volitional":[265],"exhaustion.":[266],"calculated":[270],"ventilations":[274],"as":[279,360,412],"follows:":[280],"=":[283],"\u2013":[286],".":[289],"Results":[290],"peak":[292,317],"significantly":[297,339],"greater":[298],"females":[300,342],"(":[312,350,374],"<":[314,352,376],"0.05),":[315],"yet":[316],"similar":[322,384],"sexes.":[324],"average":[326],"rates":[327,423],"change":[329],"(slope)":[330],"inspiration":[335],"&":[336,427],"expiration":[337],"faster":[340,422],"than":[343],"males":[344],"0.05).":[353,377],"Finally,":[354],"PIIA":[358,381,440],"(expressed":[359],"fraction":[362],"time)":[365],"decreased":[367],"increasing":[369],"This":[378,449],"reduction":[379],"however":[383],"women.":[388],"Conclusion":[389],"primary":[391],"finding":[392],"pattern":[399],"different":[405],"cycling,":[410],"insofar":[411],"displayed":[414],"larger":[416],",":[420],"pressure\u2010development":[429],"matched":[434],"ventilations.":[435],"However,":[436],"observed.":[444],"Support":[445],"or":[446],"Funding":[447],"Information":[448],"research":[450],"funded":[452],"by":[453,458,466],"preliminary":[454],"data":[455],"funds":[456],"provided":[457],"Northern":[459],"Arizona":[460],"University":[461],"(JWD).":[462],"TJC":[463],"supported":[465],"Irene":[468],"Diamond":[469],"Fund/American":[470],"Federation":[471],"Aging":[473],"Research":[474],"Postdoctoral":[475],"Transition":[476],"Award":[477],"time":[480],"study.":[483]},"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2020-04-24T00:00:00"}