{"id":"https://openalex.org/W3015765404","doi":"https://doi.org/10.1186/s12938-020-00763-6","title":"A real-time system for selectively sensing and pacing the His-bundle during sinus rhythm and ventricular fibrillation","display_name":"A real-time system for selectively sensing and pacing the His-bundle during sinus rhythm and ventricular fibrillation","publication_year":2020,"publication_date":"2020-04-10","ids":{"openalex":"https://openalex.org/W3015765404","doi":"https://doi.org/10.1186/s12938-020-00763-6","mag":"3015765404","pmid":"https://pubmed.ncbi.nlm.nih.gov/32276597","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7146996"},"language":"en","primary_location":{"id":"doi:10.1186/s12938-020-00763-6","doi":"https://doi.org/10.1186/s12938-020-00763-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12938-020-00763-6","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12938-020-00763-6.pdf","source":{"id":"https://openalex.org/S162176842","display_name":"BioMedical Engineering OnLine","issn_l":"1475-925X","issn":["1475-925X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMedical Engineering OnLine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s12938-020-00763-6.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044314839","display_name":"Ankur Shah","orcid":"https://orcid.org/0000-0002-9917-3539","observed_orcids":["https://orcid.org/0000-0002-9917-3539"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ankur R. Shah","raw_affiliation_strings":["Department of Biomedical Engineering, The University of Utah, Salt Lake City, UT, 84112, USA","Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101952172","display_name":"Muhammad S. Khan","orcid":"https://orcid.org/0000-0002-6232-2633","observed_orcids":["https://orcid.org/0000-0002-6232-2633"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Muhammad S. Khan","raw_affiliation_strings":["Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046305291","display_name":"Annie M. Hirahara","orcid":"https://orcid.org/0000-0003-4113-3929","observed_orcids":["https://orcid.org/0000-0003-4113-3929"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Annie M. Hirahara","raw_affiliation_strings":["Department of Biomedical Engineering, The University of Utah, Salt Lake City, UT, 84112, USA","Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050382960","display_name":"Matthias Lange","orcid":"https://orcid.org/0000-0001-5635-3444","observed_orcids":["https://orcid.org/0000-0001-5635-3444"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthias Lange","raw_affiliation_strings":["Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074809926","display_name":"Ravi Ranjan","orcid":"https://orcid.org/0000-0002-3321-2435","observed_orcids":["https://orcid.org/0000-0002-3321-2435"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ravi Ranjan","raw_affiliation_strings":["Department of Biomedical Engineering, The University of Utah, Salt Lake City, UT, 84112, USA","Division of Cardiovascular Medicine, Department of Internal Medicine, The University of Utah, Salt Lake City, UT, 84112, USA","Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Division of Cardiovascular Medicine, Department of Internal Medicine, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064060846","display_name":"Derek James Dosdall","orcid":"https://orcid.org/0000-0001-5059-6824","observed_orcids":["https://orcid.org/0000-0001-5059-6824"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Derek J. Dosdall","raw_affiliation_strings":["Department of Biomedical Engineering, The University of Utah, Salt Lake City, UT, 84112, USA. derek.dosdall@utah.edu","Division of Cardiothoracic Surgery, School of Medicine, Department of Surgery, The University of Utah, Salt Lake City, UT, 84112, USA. derek.dosdall@utah.edu","Division of Cardiovascular Medicine, Department of Internal Medicine, The University of Utah, Salt Lake City, UT, 84112, USA. derek.dosdall@utah.edu","Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA. derek.dosdall@utah.edu","Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, The University of Utah, Salt Lake City, UT, 84112, USA. derek.dosdall@utah.edu","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Division of Cardiothoracic Surgery, School of Medicine, Department of Surgery, The University of Utah, Salt Lake City, UT, 84112, USA. derek.dosdall@utah.edu","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Division of Cardiovascular Medicine, Department of Internal Medicine, The University of Utah, Salt Lake City, UT, 84112, USA. derek.dosdall@utah.edu","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA. derek.dosdall@utah.edu","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Nora Eccles Harrison Cardiovascular Research and Training Institute, The University of Utah, Salt Lake City, UT, 84112, USA","institution_ids":["https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5064060846"],"corresponding_institution_ids":["https://openalex.org/I223532165"],"apc_list":{"value":2040,"currency":"USD","value_usd":2040},"apc_paid":{"value":2040,"currency":"USD","value_usd":2040},"fwci":0.3094,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.59242959,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"19","issue":"1","first_page":"19","last_page":"19"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.02290000021457672,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/his-bundle","display_name":"His bundle","score":0.847000002861023},{"id":"https://openalex.org/keywords/his-purkinje-system","display_name":"His-Purkinje system","score":0.9829999804496765},{"id":"https://openalex.org/keywords/his-bundle-pacing","display_name":"His bundle pacing","score":0.6539999842643738},{"id":"https://openalex.org/keywords/ventricular-fibrillation","display_name":"ventricular fibrillation","score":0.8870000243186951},{"id":"https://openalex.org/keywords/sinus-rhythm","display_name":"sinus rhythm","score":0.7820000052452087},{"id":"https://openalex.org/keywords/cardiac-electrophysiology","display_name":"cardiac electrophysiology","score":0.6869999766349792},{"id":"https://openalex.org/keywords/bradycardia","display_name":"bradycardia","score":0.7559999823570251},{"id":"https://openalex.org/keywords/rabbit-heart","display_name":"rabbit heart","score":0.671999990940094}],"concepts":[{"id":"https://openalex.org/C2775914520","wikidata":"https://www.wikidata.org/wiki/Q12335414","display_name":"Sinus rhythm","level":3,"score":0.5902321934700012},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.5055887699127197},{"id":"https://openalex.org/C2781005686","wikidata":"https://www.wikidata.org/wiki/Q848662","display_name":"Ventricular fibrillation","level":2,"score":0.48548319935798645},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.47354573011398315},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4474999010562897},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.4379716217517853},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.42577216029167175},{"id":"https://openalex.org/C2778134712","wikidata":"https://www.wikidata.org/wiki/Q1047307","display_name":"Bundle","level":2,"score":0.42237621545791626},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4165101647377014},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.35802268981933594},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35467422008514404},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1921636462211609},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002036","descriptor_name":"Bundle of His","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003199","descriptor_name":"Computer Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014693","descriptor_name":"Ventricular Fibrillation","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12938-020-00763-6","doi":"https://doi.org/10.1186/s12938-020-00763-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12938-020-00763-6","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12938-020-00763-6.pdf","source":{"id":"https://openalex.org/S162176842","display_name":"BioMedical Engineering OnLine","issn_l":"1475-925X","issn":["1475-925X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMedical Engineering OnLine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7146996","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7146996","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomed Eng Online","raw_type":"Text"},{"id":"pmid:32276597","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32276597","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedical engineering online","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:54d9a723e3db4dd39ba4539c2616124b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/54d9a723e3db4dd39ba4539c2616124b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioMedical Engineering OnLine, Vol 19, Iss 1, Pp 1-19 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12938-020-00763-6","doi":"https://doi.org/10.1186/s12938-020-00763-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12938-020-00763-6","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12938-020-00763-6.pdf","source":{"id":"https://openalex.org/S162176842","display_name":"BioMedical Engineering OnLine","issn_l":"1475-925X","issn":["1475-925X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMedical Engineering OnLine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1747795394","display_name":"Antitachycardia pacing and improved lead for ventricular conduction system stimulation","funder_award_id":"R01HL128752","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320317828","display_name":"Nora Eccles Treadwell Foundation","ror":"https://ror.org/028zcv790"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3015765404.pdf","grobid_xml":"https://content.openalex.org/works/W3015765404.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1461672287","https://openalex.org/W1532192357","https://openalex.org/W1925017092","https://openalex.org/W1964172311","https://openalex.org/W1968114451","https://openalex.org/W1972626509","https://openalex.org/W1995244903","https://openalex.org/W1996793396","https://openalex.org/W2016520053","https://openalex.org/W2028030768","https://openalex.org/W2030313498","https://openalex.org/W2046514878","https://openalex.org/W2051026770","https://openalex.org/W2061712828","https://openalex.org/W2064583182","https://openalex.org/W2070827870","https://openalex.org/W2072949287","https://openalex.org/W2097511250","https://openalex.org/W2101747885","https://openalex.org/W2107582723","https://openalex.org/W2126747943","https://openalex.org/W2136338601","https://openalex.org/W2140907686","https://openalex.org/W2145619195","https://openalex.org/W2158835625","https://openalex.org/W2160284637","https://openalex.org/W2169764232","https://openalex.org/W2171117792","https://openalex.org/W2328529754","https://openalex.org/W2427324706","https://openalex.org/W2562013015","https://openalex.org/W2739543602","https://openalex.org/W2764219644","https://openalex.org/W2773560100","https://openalex.org/W2886431158"],"related_works":["https://openalex.org/W3174571840","https://openalex.org/W4404439200","https://openalex.org/W3214784869","https://openalex.org/W3186277447","https://openalex.org/W4308880489","https://openalex.org/W4323928280","https://openalex.org/W2616248339","https://openalex.org/W2974825031","https://openalex.org/W3133096883","https://openalex.org/W2057995272"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,66,82,102,136,166,180,206,244],"His-Purkinje":[2],"(HP)":[3],"system":[4,21,52],"provides":[5],"a":[6,26,47,112,115,123,133,140],"pathway":[7],"for":[8,29],"the":[9,13,19,40,64,88,97,152,169,221,225,237],"time-synchronous":[10],"contraction":[11],"of":[12,18,36,94,105,142,168,188,203,215,220,236,248],"heart.":[14],"His":[15],"bundle":[16],"(HB)":[17],"HP":[20],"is":[22,246],"gaining":[23],"relevance":[24],"as":[25],"pacing":[27,96],"site":[28],"treating":[30],"non-reversible":[31],"bradyarrhythmia":[32],"despite":[33],"limited":[34],"availability":[35],"tools":[37],"to":[38,54,59,130,145,154,162,185,211,218,252,269,286],"identify":[39,60],"HB.":[41,65],"In":[42,224],"this":[43],"paper,":[44],"we":[45],"describe":[46],"real-time":[48,113,257],"stimulation":[49,164,284],"and":[50,61,118,161,191,250,261,278,282],"recording":[51],"(rt-SRS)":[53],"investigate":[55,87],"using":[56,132],"multi-electrode":[57],"techniques":[58],"selectively":[62,95],"pace":[63],"rt-SRS":[67,83,103,170,181,207,245,266],"can":[68,182,208],"not":[69],"only":[70],"be":[71,128,270],"used":[72,240],"in":[73,147,173,232,256,289],"sinus":[74],"rhythm,":[75],"but":[76],"also":[77,85],"during":[78,99,241],"ventricular":[79],"fibrillation":[80],"(VF).":[81],"will":[84],"help":[86],"so":[89],"far":[90],"unknown":[91],"causal":[92],"effects":[93],"HB":[98,228,280],"VF.":[100,242],"METHODS:":[101],"consists":[104],"preamplifiers,":[106],"data":[107,194],"acquisition":[108],"cards":[109],"interfaced":[110],"with":[111,199,258],"controller,":[114],"current":[116,119],"source,":[117],"routing":[120],"switches":[121],"on":[122],"remote":[124,137],"computer,":[125],"which":[126],"may":[127],"interrupted":[129],"stimulate":[131],"host":[134],"machine.":[135],"computer":[138],"hosts":[139],"series":[141],"algorithms":[143],"designed":[144],"aid":[146],"identifying":[148],"electrodes":[149,239,288],"directly":[150],"over":[151],"HB,":[153],"accurately":[155],"detect":[156],"activation":[157],"rates":[158],"without":[159],"over-picking,":[160],"deliver":[163],"pulses.":[165],"performance":[167],"was":[171,267],"demonstrated":[172],"seven":[174],"isolated,":[175],"perfused":[176],"rabbit":[177,226],"hearts.":[178],"RESULTS:":[179],"visualize":[183],"up":[184,210],"96":[186,222],"channels":[187],"raw":[189],"data,":[190],"spatial":[192],"derivative":[193],"at":[195],"6.25-kHz":[196],"sampling":[197],"rate":[198],"an":[200,271],"input-referred":[201],"noise":[202],"100":[204],"\u00b5V.":[205],"send":[209],"\u00b1":[212,234],"150":[213],"V":[214],"stimuli":[216],"pulses":[217,285],"any":[219],"channels.":[223],"experiments,":[227],"activations":[229,281],"were":[230],"detected":[231],"18":[233],"6.8%":[235],"64":[238],"CONCLUSIONS:":[243],"capable":[247],"measuring":[249],"responding":[251],"cardiac":[253],"electrophysiological":[254],"phenomena":[255],"precisely":[259],"timed":[260],"placed":[262],"electrical":[263],"stimuli.":[264],"This":[265],"shown":[268],"effective":[272],"research":[273],"tool":[274],"by":[275],"successfully":[276],"detecting":[277],"quantifying":[279],"delivering":[283],"selected":[287],"real-time.":[290]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-04-17T00:00:00"}