{"id":"https://openalex.org/W3015000535","doi":"https://doi.org/10.1111/cge.13748","title":"Epigenetic variations due to nutritional status in early\u2010life and its later impact on aging and disease","display_name":"Epigenetic variations due to nutritional status in early\u2010life and its later impact on aging and disease","publication_year":2020,"publication_date":"2020-04-04","ids":{"openalex":"https://openalex.org/W3015000535","doi":"https://doi.org/10.1111/cge.13748","mag":"3015000535","pmid":"https://pubmed.ncbi.nlm.nih.gov/32246454"},"language":"en","primary_location":{"id":"doi:10.1111/cge.13748","doi":"https://doi.org/10.1111/cge.13748","is_oa":false,"landing_page_url":"https://doi.org/10.1111/cge.13748","pdf_url":null,"source":{"id":"https://openalex.org/S4954800","display_name":"Clinical Genetics","issn_l":"0009-9163","issn":["0009-9163","1399-0004"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Genetics","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058415078","display_name":"Juan Carlos G\u00f3mez-Verj\u00e1n","orcid":"https://orcid.org/0000-0001-7186-8067","observed_orcids":["https://orcid.org/0000-0001-7186-8067"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Juan C. Gomez\u2010Verjan","raw_affiliation_strings":["Divisi\u00f3n de Ciencias B\u00e1sicas Instituto Nacional de Geriatr\u00eda (INGER)  Mexico City Mexico"],"raw_orcid":"https://orcid.org/0000-0001-7186-8067","affiliations":[{"raw_affiliation_string":"Divisi\u00f3n de Ciencias B\u00e1sicas Instituto Nacional de Geriatr\u00eda (INGER)  Mexico City Mexico","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034575987","display_name":"Oscar Salvador Barrera-V\u00e1zquez","orcid":"https://orcid.org/0000-0003-1662-0872","observed_orcids":["https://orcid.org/0000-0003-1662-0872"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Oscar S. Barrera\u2010V\u00e1zquez","raw_affiliation_strings":["Divisi\u00f3n de Ciencias B\u00e1sicas Instituto Nacional de Geriatr\u00eda (INGER)  Mexico City Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisi\u00f3n de Ciencias B\u00e1sicas Instituto Nacional de Geriatr\u00eda (INGER)  Mexico City Mexico","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039566205","display_name":"Lizbeth Garc\u00eda\u2010Vel\u00e1zquez","orcid":"https://orcid.org/0000-0003-2091-2130","observed_orcids":["https://orcid.org/0000-0003-2091-2130"]},"institutions":[{"id":"https://openalex.org/I4405269066","display_name":"Instituto de Investigaciones Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/02zz52s52","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4405269066"]},{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Lizbeth Garc\u00eda\u2010Vel\u00e1zquez","raw_affiliation_strings":["Departamento de Medicina Gen\u00f3mica y Toxicolog\u00eda Ambiental Instituto de Investigaciones Biom\u00e9dicas, Universidad Nacional Autonoma de Mexico  Mexico City Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Medicina Gen\u00f3mica y Toxicolog\u00eda Ambiental Instituto de Investigaciones Biom\u00e9dicas, Universidad Nacional Autonoma de Mexico  Mexico City Mexico","institution_ids":["https://openalex.org/I4405269066","https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078800339","display_name":"Rafael Samper\u2010Ternent","orcid":"https://orcid.org/0000-0002-2250-9401","observed_orcids":["https://orcid.org/0000-0002-2250-9401"]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rafael Samper\u2010Ternent","raw_affiliation_strings":["Geriatric/Sealy Center on Aging, The University of Texas Medical Branch, Galveston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Geriatric/Sealy Center on Aging, The University of Texas Medical Branch, Galveston, Texas, USA","institution_ids":["https://openalex.org/I55302922"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113390377","display_name":"Pedro Arroyo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pedro Arroyo","raw_affiliation_strings":["Divisi\u00f3n de Epidemiolog\u00eda Instituto Nacional de Geriatr\u00eda (INGER)  Mexico City Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisi\u00f3n de Epidemiolog\u00eda Instituto Nacional de Geriatr\u00eda (INGER)  Mexico City Mexico","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5058415078"],"corresponding_institution_ids":[],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":0.7087,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.56083916,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"98","issue":"4","first_page":"313","last_page":"321"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11928","display_name":"Genetic Syndromes and Imprinting","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epigenetics","display_name":"epigenetics","score":0.9589999914169312},{"id":"https://openalex.org/keywords/nutritional-status","display_name":"nutritional status","score":0.7419999837875366},{"id":"https://openalex.org/keywords/early-life-nutrition","display_name":"early life nutrition","score":0.699999988079071},{"id":"https://openalex.org/keywords/fetal-programming","display_name":"fetal programming","score":0.8109999895095825},{"id":"https://openalex.org/keywords/transgenerational-epigenetic-inheritance","display_name":"transgenerational epigenetic inheritance","score":0.9240000247955322},{"id":"https://openalex.org/keywords/malnutrition","display_name":"malnutrition","score":0.7279999852180481},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.4869999885559082},{"id":"https://openalex.org/keywords/gestational-weight-gain","display_name":"gestational weight gain","score":0.7590000033378601},{"id":"https://openalex.org/keywords/famine","display_name":"famine","score":0.5550000071525574},{"id":"https://openalex.org/keywords/epigenome","display_name":"epigenome","score":0.7110000252723694},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.9459999799728394},{"id":"https://openalex.org/keywords/disease-risk","display_name":"disease risk","score":0.6710000038146973},{"id":"https://openalex.org/keywords/socioeconomic-status","display_name":"socioeconomic status","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.7539987564086914},{"id":"https://openalex.org/C551997983","wikidata":"https://www.wikidata.org/wiki/Q12167","display_name":"Malnutrition","level":2,"score":0.6789184808731079},{"id":"https://openalex.org/C117717151","wikidata":"https://www.wikidata.org/wiki/Q3589155","display_name":"Epigenome","level":5,"score":0.6727722883224487},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5735410451889038},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5654297471046448},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5610607266426086},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5203599333763123},{"id":"https://openalex.org/C184151982","wikidata":"https://www.wikidata.org/wiki/Q7834236","display_name":"Transgenerational epigenetics","level":4,"score":0.5083534121513367},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4358527660369873},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.427667498588562},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3660033345222473},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3601652979850769},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33373117446899414},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2912725508213043},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2579444646835327},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.20773300528526306},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15983065962791443},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009752","descriptor_name":"Nutritional Status","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009752","descriptor_name":"Nutritional Status","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D047109","descriptor_name":"Fetal Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/cge.13748","doi":"https://doi.org/10.1111/cge.13748","is_oa":false,"landing_page_url":"https://doi.org/10.1111/cge.13748","pdf_url":null,"source":{"id":"https://openalex.org/S4954800","display_name":"Clinical Genetics","issn_l":"0009-9163","issn":["0009-9163","1399-0004"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Genetics","raw_type":"journal-article"},{"id":"pmid:32246454","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32246454","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical genetics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/2","score":0.6875,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":127,"referenced_works":["https://openalex.org/W278227339","https://openalex.org/W1479993901","https://openalex.org/W1506196431","https://openalex.org/W1512645138","https://openalex.org/W1564119855","https://openalex.org/W1581785133","https://openalex.org/W1808780225","https://openalex.org/W1845885410","https://openalex.org/W1900612108","https://openalex.org/W1922615383","https://openalex.org/W1932533342","https://openalex.org/W1957913826","https://openalex.org/W1965581424","https://openalex.org/W1970018638","https://openalex.org/W1973869291","https://openalex.org/W1978116664","https://openalex.org/W1983494600","https://openalex.org/W1991211399","https://openalex.org/W1992068823","https://openalex.org/W1997133722","https://openalex.org/W1997890656","https://openalex.org/W2002129580","https://openalex.org/W2002304855","https://openalex.org/W2006478519","https://openalex.org/W2006557744","https://openalex.org/W2009396016","https://openalex.org/W2010130767","https://openalex.org/W2010143280","https://openalex.org/W2013454715","https://openalex.org/W2015838103","https://openalex.org/W2016999969","https://openalex.org/W2019876832","https://openalex.org/W2031792984","https://openalex.org/W2033063191","https://openalex.org/W2033211922","https://openalex.org/W2034304637","https://openalex.org/W2036598382","https://openalex.org/W2038165419","https://openalex.org/W2045978632","https://openalex.org/W2047372093","https://openalex.org/W2048941717","https://openalex.org/W2057795409","https://openalex.org/W2061451259","https://openalex.org/W2064757899","https://openalex.org/W2069770612","https://openalex.org/W2071365780","https://openalex.org/W2072629730","https://openalex.org/W2076860616","https://openalex.org/W2083829767","https://openalex.org/W2089497296","https://openalex.org/W2089766014","https://openalex.org/W2089991249","https://openalex.org/W2090379786","https://openalex.org/W2095102047","https://openalex.org/W2098641745","https://openalex.org/W2098926940","https://openalex.org/W2100773564","https://openalex.org/W2101961001","https://openalex.org/W2102042678","https://openalex.org/W2102242260","https://openalex.org/W2105285476","https://openalex.org/W2115599658","https://openalex.org/W2116783930","https://openalex.org/W2118097581","https://openalex.org/W2121685906","https://openalex.org/W2122604500","https://openalex.org/W2122916573","https://openalex.org/W2127552529","https://openalex.org/W2127884060","https://openalex.org/W2128199088","https://openalex.org/W2130583716","https://openalex.org/W2134555277","https://openalex.org/W2135827706","https://openalex.org/W2140093065","https://openalex.org/W2143858605","https://openalex.org/W2148462747","https://openalex.org/W2149940202","https://openalex.org/W2150582640","https://openalex.org/W2151351671","https://openalex.org/W2152434143","https://openalex.org/W2153661281","https://openalex.org/W2153940014","https://openalex.org/W2156495242","https://openalex.org/W2156874253","https://openalex.org/W2161244479","https://openalex.org/W2166000404","https://openalex.org/W2166236051","https://openalex.org/W2166953117","https://openalex.org/W2177368991","https://openalex.org/W2178495277","https://openalex.org/W2179094122","https://openalex.org/W2181644490","https://openalex.org/W2183439594","https://openalex.org/W2229195607","https://openalex.org/W2302504690","https://openalex.org/W2319625000","https://openalex.org/W2336508388","https://openalex.org/W2418673831","https://openalex.org/W2491915559","https://openalex.org/W2513796604","https://openalex.org/W2550556018","https://openalex.org/W2551024407","https://openalex.org/W2556618373","https://openalex.org/W2560030233","https://openalex.org/W2560289541","https://openalex.org/W2586570290","https://openalex.org/W2591679458","https://openalex.org/W2593072195","https://openalex.org/W2611766868","https://openalex.org/W2613971698","https://openalex.org/W2615467526","https://openalex.org/W2619972691","https://openalex.org/W2766065912","https://openalex.org/W2767741810","https://openalex.org/W2789906223","https://openalex.org/W2809475529","https://openalex.org/W2811292153","https://openalex.org/W2896387787","https://openalex.org/W2919973548","https://openalex.org/W2922188655","https://openalex.org/W2943080317","https://openalex.org/W2950402100","https://openalex.org/W2961982820","https://openalex.org/W2990266671","https://openalex.org/W2990335303","https://openalex.org/W4236663618","https://openalex.org/W6602063838"],"related_works":["https://openalex.org/W80074585","https://openalex.org/W4287845879","https://openalex.org/W4200363425","https://openalex.org/W2044868915","https://openalex.org/W1527272828","https://openalex.org/W7067863076","https://openalex.org/W4391420307","https://openalex.org/W2770310885","https://openalex.org/W2080133002","https://openalex.org/W2620877627"],"abstract_inverted_index":{"Epigenetics":[0],"refers":[1],"to":[2,62,90,173],"changes":[3,69],"in":[4,131,153],"gene":[5],"function,":[6],"not":[7],"resulting":[8],"from":[9,135,179],"the":[10,16,23,27,30,35,56,71,85,123,142,160,168,175,180,185,190],"primary":[11],"DNA":[12],"sequence,":[13],"influenced":[14,54],"by":[15,55,79],"environment.":[17],"It":[18],"provides":[19],"a":[20],"link":[21],"between":[22],"molecular":[24],"regulation":[25],"of":[26,37,84,87,111,122,128,145,163,187],"genome":[28],"and":[29,44,75,93,100,115,119,165],"environmental":[31],"signals":[32],"exposed":[33],"during":[34,98],"life":[36],"individuals":[38],"(including":[39],"lifestyle,":[40],"social":[41],"behavior,":[42],"development,":[43],"nutrition).":[45],"Notably,":[46],"early":[47],"development":[48],"(intrauterine":[49],"or":[50,64],"postnatal)":[51],"is":[52],"highly":[53],"adverse":[57,116],"socioeconomic":[58],"status":[59],"that":[60,139],"leads":[61],"malnutrition":[63,188],"obesity;":[65],"these":[66],"conditions":[67],"induce":[68],"over":[70],"fetal":[72],"epigenetic":[73],"programming":[74],"can":[76],"be":[77],"transferred":[78],"transgenerational":[80,161],"inheritance,":[81],"inducing":[82],"alterations":[83],"transcription":[86],"genes":[88],"related":[89],"several":[91],"metabolic":[92],"neurological":[94],"processes.":[95],"Moreover,":[96],"obesity":[97],"pregnancy,":[99],"excessive":[101],"gestational":[102],"weight":[103],"gain":[104],"are":[105],"associated":[106],"with":[107],"an":[108],"increased":[109],"risk":[110],"fatal":[112],"pregnancy":[113],"complications,":[114],"cardio-metabolic,":[117],"respiratory":[118],"cognitive-related":[120],"outcomes":[121],"future":[124],"child.":[125],"However,":[126],"most":[127,176,181],"our":[129],"knowledge":[130],"this":[132,148],"field":[133],"comes":[134],"experimental":[136],"animal":[137],"models,":[138],"partially":[140],"resemble":[141],"nutritional":[143,150],"effects":[144,151,162],"humans.":[146],"In":[147,167],"context,":[149],"implicated":[152],"historical":[154],"famines":[155,183],"represent":[156],"valuable":[157],"information":[158],"about":[159,184],"undernutrition":[164],"stress.":[166],"present":[169],"review,":[170],"we":[171],"attempt":[172],"describe":[174],"outstanding":[177],"results":[178],"studied":[182],"impact":[186],"on":[189],"epigenome.":[191]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-04-10T00:00:00"}