{"id":"https://openalex.org/W3014294573","doi":"https://doi.org/10.1016/j.cdtm.2020.02.005","title":"Environmental heavy metals and cardiovascular diseases: Status and future direction","display_name":"Environmental heavy metals and cardiovascular diseases: Status and future direction","publication_year":2020,"publication_date":"2020-04-03","ids":{"openalex":"https://openalex.org/W3014294573","doi":"https://doi.org/10.1016/j.cdtm.2020.02.005","mag":"3014294573","pmid":"https://pubmed.ncbi.nlm.nih.gov/33336170"},"language":"en","primary_location":{"id":"doi:10.1016/j.cdtm.2020.02.005","doi":"https://doi.org/10.1016/j.cdtm.2020.02.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cdtm.2020.02.005","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.cdtm.2020.02.005","source":{"id":"https://openalex.org/S2898558041","display_name":"Chronic Diseases and Translational Medicine","issn_l":"2095-882X","issn":["2095-882X","2589-0514"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320346","host_organization_name":"KeAi","host_organization_lineage":["https://openalex.org/P4310320346","https://openalex.org/P4310319982"],"host_organization_lineage_names":["KeAi","Science Press"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chronic Diseases and Translational Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.cdtm.2020.02.005","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020273125","display_name":"Aimin Yang","orcid":"https://orcid.org/0000-0003-2968-1762","observed_orcids":["https://orcid.org/0000-0003-2968-1762"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["HK","US"],"is_corresponding":false,"raw_author_name":"Ai\u2010Min Yang","raw_affiliation_strings":["Centre for Global Cardiometabolic Health Department of Epidemiology, Surgery, and Medicine Brown University Providence RI 02903 USA","Department of Epidemiology School of Public Health Brown University Providence RI 02903 USA","Hong Kong Institute of Diabetes and Obesity The Chinese University of Hong Kong Hong Kong SAR China","Ai-Min Yang and Kenneth Lo contributed equally to this work","Centre for Global Cardiometabolic Health, Department of Epidemiology, Surgery, and Medicine, Brown University, Providence, RI, 02903 USA","Department of Epidemiology, School of Public Health, Brown University, Providence, RI, 02903 USA","Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Global Cardiometabolic Health Department of Epidemiology, Surgery, and Medicine Brown University Providence RI 02903 USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Epidemiology School of Public Health Brown University Providence RI 02903 USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Hong Kong Institute of Diabetes and Obesity The Chinese University of Hong Kong Hong Kong SAR China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Ai-Min Yang and Kenneth Lo contributed equally to this work","institution_ids":[]},{"raw_affiliation_string":"Centre for Global Cardiometabolic Health, Department of Epidemiology, Surgery, and Medicine, Brown University, Providence, RI, 02903 USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, Brown University, Providence, RI, 02903 USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063090109","display_name":"Kenneth Ka-Hei Lo","orcid":"https://orcid.org/0000-0003-4624-2737","observed_orcids":["https://orcid.org/0000-0003-4624-2737"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth Lo","raw_affiliation_strings":["Centre for Global Cardiometabolic Health Department of Epidemiology, Surgery, and Medicine Brown University Providence RI 02903 USA","Department of Epidemiology School of Public Health Brown University Providence RI 02903 USA","Ai-Min Yang and Kenneth Lo contributed equally to this work","Department of Epidemiology, School of Public Health, Brown University, Providence, RI, 02903 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Global Cardiometabolic Health Department of Epidemiology, Surgery, and Medicine Brown University Providence RI 02903 USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Epidemiology School of Public Health Brown University Providence RI 02903 USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Ai-Min Yang and Kenneth Lo contributed equally to this work","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, Brown University, Providence, RI, 02903 USA","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103025722","display_name":"Tongzhang Zheng","orcid":"https://orcid.org/0000-0003-0155-7540","observed_orcids":["https://orcid.org/0000-0003-0155-7540"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tong\u2010Zhang Zheng","raw_affiliation_strings":["Department of Epidemiology School of Public Health Brown University Providence RI 02903 USA","Department of Epidemiology, School of Public Health, Brown University, Providence, RI, 02903 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology School of Public Health Brown University Providence RI 02903 USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, Brown University, Providence, RI, 02903 USA","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065693501","display_name":"Jing Yang","orcid":"https://orcid.org/0000-0003-0773-494X","observed_orcids":["https://orcid.org/0000-0003-0773-494X"]},"institutions":[{"id":"https://openalex.org/I76214153","display_name":"Lanzhou University","ror":"https://ror.org/01mkqqe32","country_code":"CN","type":"education","lineage":["https://openalex.org/I76214153"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing\u2010Li Yang","raw_affiliation_strings":["Department of Epidemiology School of Public Health Lanzhou University Lanzhou Gansu 730000 China","Department of Epidemiology, School of Public Health, Lanzhou University, Lanzhou, Gansu, 730000 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology School of Public Health Lanzhou University Lanzhou Gansu 730000 China","institution_ids":["https://openalex.org/I76214153"]},{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, Lanzhou University, Lanzhou, Gansu, 730000 China","institution_ids":["https://openalex.org/I76214153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090633759","display_name":"Yana Bai","orcid":"https://orcid.org/0000-0002-9563-1723","observed_orcids":["https://orcid.org/0000-0002-9563-1723"]},"institutions":[{"id":"https://openalex.org/I76214153","display_name":"Lanzhou University","ror":"https://ror.org/01mkqqe32","country_code":"CN","type":"education","lineage":["https://openalex.org/I76214153"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ya\u2010Na Bai","raw_affiliation_strings":["Department of Epidemiology School of Public Health Lanzhou University Lanzhou Gansu 730000 China","Department of Epidemiology, School of Public Health, Lanzhou University, Lanzhou, Gansu, 730000 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology School of Public Health Lanzhou University Lanzhou Gansu 730000 China","institution_ids":["https://openalex.org/I76214153"]},{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, Lanzhou University, Lanzhou, Gansu, 730000 China","institution_ids":["https://openalex.org/I76214153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051705302","display_name":"Yingqing Feng","orcid":"https://orcid.org/0000-0003-0443-5506","observed_orcids":["https://orcid.org/0000-0003-0443-5506"]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying\u2010Qing Feng","raw_affiliation_strings":["Department of Cardiology and Endocrinology Guangdong Provincial People's Hospital Guandong Academy of Medical Sciences Guangzhou Guangdong 510080 China","Department of Cardiology and Endocrinology, Guangdong Provincial People's Hospital, Guandong Academy of Medical Sciences, Guangzhou, Guangdong, 510080 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Endocrinology Guangdong Provincial People's Hospital Guandong Academy of Medical Sciences Guangzhou Guangdong 510080 China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930"]},{"raw_affiliation_string":"Department of Cardiology and Endocrinology, Guangdong Provincial People's Hospital, Guandong Academy of Medical Sciences, Guangzhou, Guangdong, 510080 China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101636400","display_name":"Ning Cheng","orcid":"https://orcid.org/0000-0003-1978-694X","observed_orcids":["https://orcid.org/0000-0003-1978-694X"]},"institutions":[{"id":"https://openalex.org/I76214153","display_name":"Lanzhou University","ror":"https://ror.org/01mkqqe32","country_code":"CN","type":"education","lineage":["https://openalex.org/I76214153"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ning Cheng","raw_affiliation_strings":["Department of Epidemiology School of Public Health Lanzhou University Lanzhou Gansu 730000 China","Department of Epidemiology, School of Public Health, Lanzhou University, Lanzhou, Gansu, 730000 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology School of Public Health Lanzhou University Lanzhou Gansu 730000 China","institution_ids":["https://openalex.org/I76214153"]},{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, Lanzhou University, Lanzhou, Gansu, 730000 China","institution_ids":["https://openalex.org/I76214153"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100607135","display_name":"Simin Liu","orcid":"https://orcid.org/0000-0003-2098-3844","observed_orcids":["https://orcid.org/0000-0003-2098-3844"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["HK","US"],"is_corresponding":true,"raw_author_name":"Si\u2010Min Liu","raw_affiliation_strings":["Centre for Global Cardiometabolic Health Department of Epidemiology, Surgery, and Medicine Brown University Providence RI 02903 USA","Hong Kong Institute of Diabetes and Obesity The Chinese University of Hong Kong Hong Kong SAR China","Centre for Global Cardiometabolic Health, Department of Epidemiology, Surgery, and Medicine, Brown University, Providence, RI, 02903 USA","Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Global Cardiometabolic Health Department of Epidemiology, Surgery, and Medicine Brown University Providence RI 02903 USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Hong Kong Institute of Diabetes and Obesity The Chinese University of Hong Kong Hong Kong SAR China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Centre for Global Cardiometabolic Health, Department of Epidemiology, Surgery, and Medicine, Brown University, Providence, RI, 02903 USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China","institution_ids":["https://openalex.org/I177725633"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100607135"],"corresponding_institution_ids":["https://openalex.org/I177725633","https://openalex.org/I27804330"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":null,"fwci":6.9094,"has_fulltext":true,"cited_by_count":174,"citation_normalized_percentile":{"value":0.98602235,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"6","issue":"4","first_page":"251","last_page":"259"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10139","display_name":"Heavy metals in environment","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heavy-metals","display_name":"heavy metals","score":0.7940000295639038},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.8920000195503235},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.7720000147819519},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":1.0},{"id":"https://openalex.org/keywords/environmental-exposure","display_name":"environmental exposure","score":0.675000011920929},{"id":"https://openalex.org/keywords/cardiometabolic-health","display_name":"cardiometabolic health","score":0.8180000185966492},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.8180000185966492},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.878000020980835},{"id":"https://openalex.org/keywords/biological-mechanisms","display_name":"biological mechanisms","score":0.7680000066757202},{"id":"https://openalex.org/keywords/low-and-middle-income-countries","display_name":"low- and middle-income countries","score":0.9480000138282776},{"id":"https://openalex.org/keywords/environmental-degradation","display_name":"environmental degradation","score":0.5040000081062317},{"id":"https://openalex.org/keywords/exposure-assessment","display_name":"exposure assessment","score":0.5730000138282776}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8949362635612488},{"id":"https://openalex.org/C2776053758","wikidata":"https://www.wikidata.org/wiki/Q105789","display_name":"Heavy metals","level":2,"score":0.6888912320137024},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.40001624822616577},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.20331057906150818},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.cdtm.2020.02.005","doi":"https://doi.org/10.1016/j.cdtm.2020.02.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cdtm.2020.02.005","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.cdtm.2020.02.005","source":{"id":"https://openalex.org/S2898558041","display_name":"Chronic Diseases and Translational Medicine","issn_l":"2095-882X","issn":["2095-882X","2589-0514"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320346","host_organization_name":"KeAi","host_organization_lineage":["https://openalex.org/P4310320346","https://openalex.org/P4310319982"],"host_organization_lineage_names":["KeAi","Science Press"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chronic Diseases and Translational Medicine","raw_type":"journal-article"},{"id":"pmid:33336170","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33336170","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chronic diseases and translational medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7729107","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7729107","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chronic Dis Transl Med","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:6bf588fa8ff7473f88e3c6349cb8b40c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6bf588fa8ff7473f88e3c6349cb8b40c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chronic Diseases and Translational Medicine, Vol 6, Iss 4, Pp 251-259 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.cdtm.2020.02.005","doi":"https://doi.org/10.1016/j.cdtm.2020.02.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cdtm.2020.02.005","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.cdtm.2020.02.005","source":{"id":"https://openalex.org/S2898558041","display_name":"Chronic Diseases and Translational Medicine","issn_l":"2095-882X","issn":["2095-882X","2589-0514"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320346","host_organization_name":"KeAi","host_organization_lineage":["https://openalex.org/P4310320346","https://openalex.org/P4310319982"],"host_organization_lineage_names":["KeAi","Science Press"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chronic Diseases and Translational Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.47999998927116394,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4994789454","display_name":null,"funder_award_id":"R01 ES031391","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"}],"funders":[{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3014294573.pdf","grobid_xml":"https://content.openalex.org/works/W3014294573.grobid-xml"},"referenced_works_count":151,"referenced_works":["https://openalex.org/W2178751","https://openalex.org/W142588538","https://openalex.org/W1517917246","https://openalex.org/W1643083998","https://openalex.org/W1837971989","https://openalex.org/W1859890772","https://openalex.org/W1934678104","https://openalex.org/W1962759666","https://openalex.org/W1967112367","https://openalex.org/W1968191239","https://openalex.org/W1969640318","https://openalex.org/W1970498604","https://openalex.org/W1975547862","https://openalex.org/W1976962696","https://openalex.org/W1977801597","https://openalex.org/W1984271811","https://openalex.org/W1984465004","https://openalex.org/W1986192058","https://openalex.org/W1986302630","https://openalex.org/W1986712010","https://openalex.org/W1988152695","https://openalex.org/W1988977459","https://openalex.org/W1990790739","https://openalex.org/W1992316947","https://openalex.org/W1993640667","https://openalex.org/W1994466071","https://openalex.org/W1997150588","https://openalex.org/W2004257256","https://openalex.org/W2005002747","https://openalex.org/W2006489736","https://openalex.org/W2006512813","https://openalex.org/W2006626759","https://openalex.org/W2008299637","https://openalex.org/W2010521953","https://openalex.org/W2011200430","https://openalex.org/W2011491820","https://openalex.org/W2013816446","https://openalex.org/W2015940780","https://openalex.org/W2018644811","https://openalex.org/W2019404343","https://openalex.org/W2019590128","https://openalex.org/W2021894743","https://openalex.org/W2025465588","https://openalex.org/W2026523169","https://openalex.org/W2027489875","https://openalex.org/W2029570226","https://openalex.org/W2036588459","https://openalex.org/W2038872751","https://openalex.org/W2042150263","https://openalex.org/W2044382094","https://openalex.org/W2048834825","https://openalex.org/W2050351828","https://openalex.org/W2050723198","https://openalex.org/W2051131234","https://openalex.org/W2057596304","https://openalex.org/W2058888791","https://openalex.org/W2067042334","https://openalex.org/W2067113440","https://openalex.org/W2075103663","https://openalex.org/W2079011786","https://openalex.org/W2082488244","https://openalex.org/W2083832602","https://openalex.org/W2084216767","https://openalex.org/W2084653848","https://openalex.org/W2086854084","https://openalex.org/W2087245486","https://openalex.org/W2087787127","https://openalex.org/W2092398183","https://openalex.org/W2093025338","https://openalex.org/W2095240170","https://openalex.org/W2095429485","https://openalex.org/W2096007910","https://openalex.org/W2096110490","https://openalex.org/W2097055696","https://openalex.org/W2097644754","https://openalex.org/W2100809193","https://openalex.org/W2101747997","https://openalex.org/W2105623292","https://openalex.org/W2107990933","https://openalex.org/W2109744370","https://openalex.org/W2113679049","https://openalex.org/W2113973351","https://openalex.org/W2114717499","https://openalex.org/W2115824648","https://openalex.org/W2116781782","https://openalex.org/W2122158699","https://openalex.org/W2125458003","https://openalex.org/W2126528010","https://openalex.org/W2132474940","https://openalex.org/W2133461561","https://openalex.org/W2133714917","https://openalex.org/W2134527572","https://openalex.org/W2135014404","https://openalex.org/W2135767337","https://openalex.org/W2138912731","https://openalex.org/W2140267946","https://openalex.org/W2140665078","https://openalex.org/W2145433807","https://openalex.org/W2145635335","https://openalex.org/W2147928285","https://openalex.org/W2147952259","https://openalex.org/W2148540549","https://openalex.org/W2151413938","https://openalex.org/W2152285045","https://openalex.org/W2152692075","https://openalex.org/W2153015540","https://openalex.org/W2154013942","https://openalex.org/W2155193274","https://openalex.org/W2155857862","https://openalex.org/W2156012627","https://openalex.org/W2156620218","https://openalex.org/W2161136053","https://openalex.org/W2161428742","https://openalex.org/W2161552991","https://openalex.org/W2165793952","https://openalex.org/W2165834654","https://openalex.org/W2165898446","https://openalex.org/W2167472088","https://openalex.org/W2169567628","https://openalex.org/W2171336778","https://openalex.org/W2267430003","https://openalex.org/W2277182879","https://openalex.org/W2322726460","https://openalex.org/W2331548577","https://openalex.org/W2436046942","https://openalex.org/W2461711813","https://openalex.org/W2519523583","https://openalex.org/W2548546253","https://openalex.org/W2551387324","https://openalex.org/W2585099006","https://openalex.org/W2592851236","https://openalex.org/W2595709889","https://openalex.org/W2604643245","https://openalex.org/W2751792491","https://openalex.org/W2752032548","https://openalex.org/W2790222065","https://openalex.org/W2791453970","https://openalex.org/W2791487255","https://openalex.org/W2801871393","https://openalex.org/W2803191710","https://openalex.org/W2809384953","https://openalex.org/W2886397848","https://openalex.org/W2888857894","https://openalex.org/W2889348359","https://openalex.org/W2898184483","https://openalex.org/W2906461844","https://openalex.org/W3026227461","https://openalex.org/W3140799612","https://openalex.org/W3143378604","https://openalex.org/W3147681457","https://openalex.org/W6734591494"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725"],"abstract_inverted_index":{"Cardiovascular":[0],"disease":[1],"(CVD)":[2],"and":[3,27,34,51,69,85,108,142,180,187,202],"environmental":[4,163],"degradation":[5],"are":[6],"leading":[7],"global":[8],"health":[9,198],"problems":[10],"of":[11,25,53,65,103,124,128,137,140,162,177,191,200],"our":[12,90],"time.":[13],"Recent":[14],"studies":[15,110,131],"have":[16],"linked":[17],"exposure":[18,112,148,194],"to":[19,22,62,113,149,157,181,185],"heavy":[20,59,114,150,192],"metals":[21],"the":[23,48,54,63,75,121,146,189,196],"risks":[24],"CVD":[26,66,171],"diabetes,":[28],"particularly":[29],"in":[30,83,89,97,116,120,174],"populations":[31],"from":[32,105],"low-":[33],"middle-income":[35],"countries,":[36],"where":[37],"concomitant":[38],"rapid":[39],"development":[40],"occurs.":[41],"In":[42],"this":[43],"review,":[44],"we":[45],"1)":[46],"assessed":[47],"totality,":[49],"quantity,":[50],"consistency":[52],"available":[55],"epidemiological":[56],"studies,":[57],"linking":[58],"metal":[60,193],"exposures":[61],"risk":[64,123],"(including":[67],"stroke":[68],"coronary":[70],"heart":[71],"disease);":[72],"2)":[73],"discussed":[74],"potential":[76,183],"biological":[77],"mechanisms":[78],"underlying":[79],"some":[80],"tantalizing":[81],"observations":[82],"humans;":[84],"3)":[86],"identified":[87],"gaps":[88],"knowledge":[91],"base":[92],"that":[93],"must":[94],"be":[95],"investigated":[96],"future":[98],"work.":[99],"An":[100],"accumulating":[101],"body":[102],"evidence":[104],"both":[106],"experimental":[107],"observational":[109],"implicates":[111],"metals,":[115,151],"a":[117],"dose-response":[118],"manner,":[119],"increased":[122],"CVD.":[125],"The":[126],"limitations":[127],"most":[129],"existing":[130],"include":[132],"insufficient":[133],"statistical":[134],"power,":[135],"lack":[136],"comprehensive":[138],"assessment":[139],"exposure,":[141],"cross-sectional":[143],"design.":[144],"Given":[145],"widespread":[147],"an":[152],"urgent":[153],"need":[154],"has":[155],"emerged":[156],"investigate":[158],"these":[159],"putative":[160],"associations":[161],"exposures,":[164],"either":[165],"independently":[166],"or":[167],"jointly,":[168],"with":[169],"incident":[170],"outcomes":[172,199],"prospectively":[173],"well-characterized":[175],"cohorts":[176],"diverse":[178],"populations,":[179],"determine":[182],"strategies":[184],"prevent":[186],"control":[188],"impacts":[190],"on":[195],"cardiometabolic":[197],"individuals":[201],"populations.":[203]},"counts_by_year":[{"year":2026,"cited_by_count":21},{"year":2025,"cited_by_count":38},{"year":2024,"cited_by_count":37},{"year":2023,"cited_by_count":26},{"year":2022,"cited_by_count":31},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":4}],"updated_date":"2026-10-21T09:56:26.102985","created_date":"2025-10-10T00:00:00"}
