{"id":"https://openalex.org/W3014100409","doi":"https://doi.org/10.1063/1.5144135","title":"Microfluidic methods for precision diagnostics in food allergy","display_name":"Microfluidic methods for precision diagnostics in food allergy","publication_year":2020,"publication_date":"2020-03-01","ids":{"openalex":"https://openalex.org/W3014100409","doi":"https://doi.org/10.1063/1.5144135","mag":"3014100409","pmid":"https://pubmed.ncbi.nlm.nih.gov/32266046"},"language":"en","primary_location":{"id":"doi:10.1063/1.5144135","doi":"https://doi.org/10.1063/1.5144135","is_oa":false,"landing_page_url":"https://doi.org/10.1063/1.5144135","pdf_url":null,"source":{"id":"https://openalex.org/S173107507","display_name":"Biomicrofluidics","issn_l":"1932-1058","issn":["1932-1058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7127910","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038454831","display_name":"Nicolas Casta\u00f1o","orcid":"https://orcid.org/0000-0002-9244-3313","observed_orcids":["https://orcid.org/0000-0002-9244-3313"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicolas Casta\u00f1o","raw_affiliation_strings":["Department of Mechanical Engineering, Stanford University 1 , Stanford, California 94305, USA"],"raw_orcid":"https://orcid.org/0000-0002-9244-3313","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Stanford University 1 , Stanford, California 94305, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082167009","display_name":"Seth C. Cordts","orcid":"https://orcid.org/0000-0003-3464-013X","observed_orcids":["https://orcid.org/0000-0003-3464-013X"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seth C. Cordts","raw_affiliation_strings":["Department of Mechanical Engineering, Stanford University 1 , Stanford, California 94305, USA"],"raw_orcid":"https://orcid.org/0000-0003-3464-013X","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Stanford University 1 , Stanford, California 94305, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028760615","display_name":"Kari Christine Nadeau","orcid":"https://orcid.org/0000-0002-2146-2955","observed_orcids":["https://orcid.org/0000-0002-2146-2955"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kari C. Nadeau","raw_affiliation_strings":["Department of Pediatrics\u2014Allergy and Clinical Immunology, Stanford University 2 , Stanford, California 94305, USA"],"raw_orcid":"https://orcid.org/0000-0002-2146-2955","affiliations":[{"raw_affiliation_string":"Department of Pediatrics\u2014Allergy and Clinical Immunology, Stanford University 2 , Stanford, California 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010135113","display_name":"Mindy M Tsai","orcid":"https://orcid.org/0000-0002-8421-4721","observed_orcids":["https://orcid.org/0000-0002-8421-4721"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mindy Tsai","raw_affiliation_strings":["Department of Pathology, Stanford University 3 , Stanford, California 94305, USA"],"raw_orcid":"https://orcid.org/0000-0002-8421-4721","affiliations":[{"raw_affiliation_string":"Department of Pathology, Stanford University 3 , Stanford, California 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004151297","display_name":"Stephen Joseph Galli","orcid":"https://orcid.org/0000-0001-5736-5340","observed_orcids":["https://orcid.org/0000-0001-5736-5340"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen J. Galli","raw_affiliation_strings":["Department of Microbiology and Immunology, Stanford University 4 , Stanford, California 94305, USA","Department of Pathology, Stanford University 3 , Stanford, California 94305, USA"],"raw_orcid":"https://orcid.org/0000-0001-5736-5340","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Stanford University 4 , Stanford, California 94305, USA","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Pathology, Stanford University 3 , Stanford, California 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019601221","display_name":"Sindy K. Y. Tang","orcid":"https://orcid.org/0000-0003-1465-2432","observed_orcids":["https://orcid.org/0000-0003-1465-2432"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sindy K. Y. Tang","raw_affiliation_strings":["Department of Mechanical Engineering, Stanford University 1 , Stanford, California 94305, USA"],"raw_orcid":"https://orcid.org/0000-0003-1465-2432","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Stanford University 1 , Stanford, California 94305, USA","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.938,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.72462017,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"14","issue":"2","first_page":"021503","last_page":"021503"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.6226000189781189,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.6226000189781189,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.33739998936653137,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.012600000016391277,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/food-allergy","display_name":"food allergy","score":0.9869999885559082},{"id":"https://openalex.org/keywords/microfluidics","display_name":"microfluidics","score":0.9120000004768372},{"id":"https://openalex.org/keywords/precision-diagnosis","display_name":"precision diagnostics","score":0.9769999980926514},{"id":"https://openalex.org/keywords/food-allergy-diagnosis","display_name":"food allergy diagnosis","score":0.6869999766349792},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.9039999842643738},{"id":"https://openalex.org/keywords/in-vitro-diagnostics","display_name":"in vitro diagnostics","score":0.9559999704360962},{"id":"https://openalex.org/keywords/oral-food-challenge","display_name":"oral food challenge","score":0.8289999961853027},{"id":"https://openalex.org/keywords/multiplexed-biomarker-detection","display_name":"multiplexed biomarker detection","score":0.8550000190734863},{"id":"https://openalex.org/keywords/immune-cells","display_name":"immune cells","score":0.7739999890327454},{"id":"https://openalex.org/keywords/multi-organ-on-a-chip","display_name":"multi-organ-on-a-chip","score":0.8989999890327454},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C2776027960","wikidata":"https://www.wikidata.org/wiki/Q769815","display_name":"Food allergy","level":3,"score":0.8169107437133789},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.5277063250541687},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.4832673668861389},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.46670103073120117},{"id":"https://openalex.org/C40993552","wikidata":"https://www.wikidata.org/wiki/Q514654","display_name":"Gold standard (test)","level":2,"score":0.4622838795185089},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4493539333343506},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42711108922958374},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3237462043762207},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2877773642539978},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.241853266954422},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07727110385894775},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1063/1.5144135","doi":"https://doi.org/10.1063/1.5144135","is_oa":false,"landing_page_url":"https://doi.org/10.1063/1.5144135","pdf_url":null,"source":{"id":"https://openalex.org/S173107507","display_name":"Biomicrofluidics","issn_l":"1932-1058","issn":["1932-1058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"journal-article"},{"id":"pmid:32266046","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32266046","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7127910","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7127910","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biomicrofluidics","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7127910","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7127910","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biomicrofluidics","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.7099999785423279,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000872024","display_name":"Integrated Genomic and Functional Studies of Immunotherapy for Multi-Food Allergy","funder_award_id":"U19AI104209","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":108,"referenced_works":["https://openalex.org/W337186158","https://openalex.org/W1963545949","https://openalex.org/W1964841318","https://openalex.org/W1965954059","https://openalex.org/W1966646357","https://openalex.org/W1971905966","https://openalex.org/W1979622850","https://openalex.org/W1981121371","https://openalex.org/W1986547754","https://openalex.org/W1995299246","https://openalex.org/W1997051144","https://openalex.org/W2002004901","https://openalex.org/W2002163498","https://openalex.org/W2003972355","https://openalex.org/W2008386994","https://openalex.org/W2013307032","https://openalex.org/W2015659263","https://openalex.org/W2021246855","https://openalex.org/W2021890997","https://openalex.org/W2023228944","https://openalex.org/W2027806997","https://openalex.org/W2031972699","https://openalex.org/W2039521240","https://openalex.org/W2039881290","https://openalex.org/W2042242299","https://openalex.org/W2043369438","https://openalex.org/W2044605236","https://openalex.org/W2046984705","https://openalex.org/W2047977056","https://openalex.org/W2049082059","https://openalex.org/W2055525472","https://openalex.org/W2055794022","https://openalex.org/W2060745308","https://openalex.org/W2061860378","https://openalex.org/W2061993413","https://openalex.org/W2069026988","https://openalex.org/W2069780509","https://openalex.org/W2071520161","https://openalex.org/W2074795260","https://openalex.org/W2074887116","https://openalex.org/W2079868760","https://openalex.org/W2085769623","https://openalex.org/W2091469647","https://openalex.org/W2094588486","https://openalex.org/W2094810816","https://openalex.org/W2100151077","https://openalex.org/W2105176378","https://openalex.org/W2111310940","https://openalex.org/W2111331204","https://openalex.org/W2117526433","https://openalex.org/W2119111881","https://openalex.org/W2124964751","https://openalex.org/W2129147449","https://openalex.org/W2133827756","https://openalex.org/W2136186943","https://openalex.org/W2137682839","https://openalex.org/W2143867049","https://openalex.org/W2153292496","https://openalex.org/W2155597751","https://openalex.org/W2156678619","https://openalex.org/W2159112247","https://openalex.org/W2161018541","https://openalex.org/W2161617166","https://openalex.org/W2165032821","https://openalex.org/W2165696748","https://openalex.org/W2168752825","https://openalex.org/W2171704681","https://openalex.org/W2285618087","https://openalex.org/W2315179197","https://openalex.org/W2328580513","https://openalex.org/W2493558455","https://openalex.org/W2511126932","https://openalex.org/W2545836320","https://openalex.org/W2592720475","https://openalex.org/W2607332990","https://openalex.org/W2612974840","https://openalex.org/W2622124591","https://openalex.org/W2626389363","https://openalex.org/W2739225905","https://openalex.org/W2746697780","https://openalex.org/W2752928520","https://openalex.org/W2766034570","https://openalex.org/W2770868505","https://openalex.org/W2781669675","https://openalex.org/W2781760652","https://openalex.org/W2783384773","https://openalex.org/W2786927254","https://openalex.org/W2789933186","https://openalex.org/W2793132326","https://openalex.org/W2794650066","https://openalex.org/W2800164512","https://openalex.org/W2800242771","https://openalex.org/W2800664372","https://openalex.org/W2883777049","https://openalex.org/W2888603931","https://openalex.org/W2895325457","https://openalex.org/W2898024988","https://openalex.org/W2898529963","https://openalex.org/W2898952866","https://openalex.org/W2901166761","https://openalex.org/W2901755923","https://openalex.org/W2901872839","https://openalex.org/W2905385220","https://openalex.org/W2914129395","https://openalex.org/W2939376263","https://openalex.org/W2989717069","https://openalex.org/W3142188131","https://openalex.org/W4234708740"],"related_works":["https://openalex.org/W2999019468","https://openalex.org/W4282827537","https://openalex.org/W146695597","https://openalex.org/W2150418084","https://openalex.org/W2915108237","https://openalex.org/W2790655502","https://openalex.org/W1985680139","https://openalex.org/W4223553962","https://openalex.org/W2786975864","https://openalex.org/W191983151"],"abstract_inverted_index":{"Food":[0],"allergy":[1,23,43,118],"has":[2,7],"reached":[3],"epidemic":[4],"proportions":[5],"and":[6,64,78,103,151,154],"become":[8],"a":[9,46,53,124],"significant":[10],"source":[11],"of":[12,36,71,126,144,148],"healthcare":[13],"burden.":[14],"Oral":[15],"food":[16,22,42,92,117,138],"challenge,":[17],"the":[18,32,69,81,110,142],"gold":[19],"standard":[20],"for":[21,56,116,129,133],"assessment,":[24],"often":[25],"is":[26,52],"not":[27],"performed":[28],"because":[29],"it":[30,95,108],"places":[31],"patient":[33],"at":[34],"risk":[35],"developing":[37],"anaphylaxis.":[38],"However,":[39],"conventional":[40,87],"alternative":[41],"tests":[44,59],"lack":[45],"sufficient":[47],"predictive":[48],"value.":[49],"Therefore,":[50],"there":[51],"critical":[54],"need":[55],"better":[57],"diagnostic":[58,88],"that":[60],"are":[61],"both":[62],"accurate":[63],"safe.":[65],"Microfluidic":[66],"methods":[67,112,132],"have":[68],"potential":[70],"helping":[72],"one":[73],"to":[74,79,99],"address":[75],"such":[76],"needs":[77],"personalize":[80],"diagnostics.":[82,106],"This":[83],"article":[84,121],"first":[85],"reviews":[86,96],"approaches":[89],"used":[90],"in":[91,104,137],"allergy.":[93],"Second,":[94],"recent":[97],"efforts":[98],"develop":[100],"novel":[101],"biomarkers":[102],"vitro":[105],"Third,":[107],"summarizes":[109],"microfluidic":[111,131],"developed":[113],"thus":[114],"far":[115],"diagnosis.":[119],"The":[120],"concludes":[122],"with":[123],"discussion":[125],"future":[127],"opportunities":[128],"using":[130],"achieving":[134],"precision":[135],"diagnostics":[136],"allergy,":[139],"including":[140],"multiplexing":[141],"detection":[143],"multiple":[145],"biomarkers,":[146],"sampling":[147],"tissue-resident":[149],"cytokines":[150],"immune":[152],"cells,":[153],"multi-organ-on-a-chip":[155],"technology.":[156]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-15T10:00:46.086208","created_date":"2025-10-10T00:00:00"}