{"id":"https://openalex.org/W3013383549","doi":"https://doi.org/10.1097/sla.0000000000003886","title":"The Impact of Adjuvant Therapy on Survival After Esophagectomy for Node-negative Esophageal Adenocarcinoma","display_name":"The Impact of Adjuvant Therapy on Survival After Esophagectomy for Node-negative Esophageal Adenocarcinoma","publication_year":2020,"publication_date":"2020-03-20","ids":{"openalex":"https://openalex.org/W3013383549","doi":"https://doi.org/10.1097/sla.0000000000003886","mag":"3013383549","pmid":"https://pubmed.ncbi.nlm.nih.gov/32209899","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7502525"},"language":"en","primary_location":{"id":"doi:10.1097/sla.0000000000003886","doi":"https://doi.org/10.1097/sla.0000000000003886","is_oa":false,"landing_page_url":"https://doi.org/10.1097/sla.0000000000003886","pdf_url":null,"source":{"id":"https://openalex.org/S157664895","display_name":"Annals of Surgery","issn_l":"0003-4932","issn":["0003-4932","1528-1140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC7502525","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005353116","display_name":"A. Justin Rucker","orcid":"https://orcid.org/0000-0001-7538-1838","observed_orcids":["https://orcid.org/0000-0001-7538-1838"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I98813999","display_name":"American College of Surgeons","ror":"https://ror.org/009mk5659","country_code":"US","type":"other","lineage":["https://openalex.org/I98813999"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Justin Rucker","raw_affiliation_strings":["Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","Type of study: Retrospective analysis of the National Cancer Database"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","institution_ids":[]},{"raw_affiliation_string":"The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","institution_ids":["https://openalex.org/I98813999"]},{"raw_affiliation_string":"Type of study: Retrospective analysis of the National Cancer Database","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016103136","display_name":"Vignesh Raman","orcid":"https://orcid.org/0000-0002-5244-9876","observed_orcids":["https://orcid.org/0000-0002-5244-9876"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I98813999","display_name":"American College of Surgeons","ror":"https://ror.org/009mk5659","country_code":"US","type":"other","lineage":["https://openalex.org/I98813999"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vignesh Raman","raw_affiliation_strings":["Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","Type of study: Retrospective analysis of the National Cancer Database"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","institution_ids":[]},{"raw_affiliation_string":"The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","institution_ids":["https://openalex.org/I98813999"]},{"raw_affiliation_string":"Type of study: Retrospective analysis of the National Cancer Database","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035615369","display_name":"Oliver K. Jawitz","orcid":"https://orcid.org/0000-0002-4753-3897","observed_orcids":["https://orcid.org/0000-0002-4753-3897"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I98813999","display_name":"American College of Surgeons","ror":"https://ror.org/009mk5659","country_code":"US","type":"other","lineage":["https://openalex.org/I98813999"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Oliver K. Jawitz","raw_affiliation_strings":["Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","Type of study: Retrospective analysis of the National Cancer Database"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","institution_ids":[]},{"raw_affiliation_string":"The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","institution_ids":["https://openalex.org/I98813999"]},{"raw_affiliation_string":"Type of study: Retrospective analysis of the National Cancer Database","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054972564","display_name":"Soraya L. Voigt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I98813999","display_name":"American College of Surgeons","ror":"https://ror.org/009mk5659","country_code":"US","type":"other","lineage":["https://openalex.org/I98813999"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Soraya L. Voigt","raw_affiliation_strings":["Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","Type of study: Retrospective analysis of the National Cancer Database"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","institution_ids":[]},{"raw_affiliation_string":"The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","institution_ids":["https://openalex.org/I98813999"]},{"raw_affiliation_string":"Type of study: Retrospective analysis of the National Cancer Database","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001948668","display_name":"David H. Harpole","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I98813999","display_name":"American College of Surgeons","ror":"https://ror.org/009mk5659","country_code":"US","type":"other","lineage":["https://openalex.org/I98813999"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David H. Harpole","raw_affiliation_strings":["Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","Type of study: Retrospective analysis of the National Cancer Database"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","institution_ids":[]},{"raw_affiliation_string":"The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","institution_ids":["https://openalex.org/I98813999"]},{"raw_affiliation_string":"Type of study: Retrospective analysis of the National Cancer Database","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104279784","display_name":"Thomas Anthony D\u2019Amico","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I98813999","display_name":"American College of Surgeons","ror":"https://ror.org/009mk5659","country_code":"US","type":"other","lineage":["https://openalex.org/I98813999"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas A. D\u2019Amico","raw_affiliation_strings":["Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","Type of study: Retrospective analysis of the National Cancer Database"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","institution_ids":[]},{"raw_affiliation_string":"The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","institution_ids":["https://openalex.org/I98813999"]},{"raw_affiliation_string":"Type of study: Retrospective analysis of the National Cancer Database","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072825952","display_name":"Betty Caroline Tong","orcid":"https://orcid.org/0000-0002-3345-3124","observed_orcids":["https://orcid.org/0000-0002-3345-3124"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I98813999","display_name":"American College of Surgeons","ror":"https://ror.org/009mk5659","country_code":"US","type":"other","lineage":["https://openalex.org/I98813999"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Betty C. Tong","raw_affiliation_strings":["Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","Type of study: Retrospective analysis of the National Cancer Database"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.annalsofsurgery.com)","institution_ids":[]},{"raw_affiliation_string":"The American College of Surgeons is in a Business Associate Agreement that includes a data use agreement with each of its Commission on Cancer accredited hospitals. The data used in the study are derived from a de-identified National Cancer Database file. The American College of Surgeons and the Commission on Cancer have not verified and are not responsible for the analytic or statistical methodology used or the conclusions drawn from these data by the investigators","institution_ids":["https://openalex.org/I98813999"]},{"raw_affiliation_string":"Type of study: Retrospective analysis of the National Cancer Database","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.7385,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.9055504,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"275","issue":"2","first_page":"348","last_page":"355"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/esophageal-adenocarcinoma","display_name":"esophageal adenocarcinoma","score":0.9750000238418579},{"id":"https://openalex.org/keywords/adjuvant-chemotherapy","display_name":"adjuvant chemotherapy","score":0.9509999752044678},{"id":"https://openalex.org/keywords/adjuvant-radiotherapy","display_name":"adjuvant radiotherapy","score":0.8080000281333923},{"id":"https://openalex.org/keywords/esophagectomy","display_name":"esophagectomy","score":0.968999981880188},{"id":"https://openalex.org/keywords/node-negative-disease","display_name":"node-negative disease","score":0.9049999713897705},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.8560000061988831},{"id":"https://openalex.org/keywords/nccn-guidelines","display_name":"NCCN guidelines","score":0.7409999966621399},{"id":"https://openalex.org/keywords/high-risk-features","display_name":"high-risk features","score":0.6610000133514404},{"id":"https://openalex.org/keywords/distal-esophagus","display_name":"distal esophagus","score":0.7770000100135803},{"id":"https://openalex.org/keywords/propensity-score-matching","display_name":"propensity score matching","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9519709944725037},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6179071664810181},{"id":"https://openalex.org/C2777297899","wikidata":"https://www.wikidata.org/wiki/Q298191","display_name":"Esophagectomy","level":4,"score":0.6037771701812744},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.6026799082756042},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.5663813352584839},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5590702295303345},{"id":"https://openalex.org/C2777982462","wikidata":"https://www.wikidata.org/wiki/Q2481887","display_name":"Adjuvant therapy","level":3,"score":0.5432296395301819},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5372974276542664},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.5047584772109985},{"id":"https://openalex.org/C2779742542","wikidata":"https://www.wikidata.org/wiki/Q372701","display_name":"Esophageal cancer","level":3,"score":0.47389286756515503},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.4278644919395447},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.42675408720970154},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4038923978805542},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3480275273323059}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016629","descriptor_name":"Esophagectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017024","descriptor_name":"Chemotherapy, Adjuvant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1097/sla.0000000000003886","doi":"https://doi.org/10.1097/sla.0000000000003886","is_oa":false,"landing_page_url":"https://doi.org/10.1097/sla.0000000000003886","pdf_url":null,"source":{"id":"https://openalex.org/S157664895","display_name":"Annals of Surgery","issn_l":"0003-4932","issn":["0003-4932","1528-1140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Surgery","raw_type":"journal-article"},{"id":"pmid:32209899","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32209899","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of surgery","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:7340647","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7502525","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7502525","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7502525","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Ann Surg","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:7340647","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7502525","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1046161961","display_name":null,"funder_award_id":"T32-HL069749","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G533394515","display_name":"Postdoctoral Training in Cardiovascular Clinical Research","funder_award_id":"5t32hl069749-20","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7571490040","display_name":"Translational Research in Surgical Oncology","funder_award_id":"T32CA093245","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000914840","display_name":"Cancer Center Support Grant (CCSG)","funder_award_id":"P30CA014236","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W2004079062","https://openalex.org/W2040085451","https://openalex.org/W2092960407","https://openalex.org/W2115072149","https://openalex.org/W2127996441","https://openalex.org/W2144182296","https://openalex.org/W2146834306","https://openalex.org/W2152849583","https://openalex.org/W2154444715","https://openalex.org/W2178359734","https://openalex.org/W2578140257","https://openalex.org/W2736419244","https://openalex.org/W2747096324","https://openalex.org/W2791876363","https://openalex.org/W2960976780","https://openalex.org/W4395473939"],"related_works":["https://openalex.org/W2948649189","https://openalex.org/W2510017640","https://openalex.org/W2810007862","https://openalex.org/W2907444225","https://openalex.org/W2166356626","https://openalex.org/W2743108317","https://openalex.org/W3167330796","https://openalex.org/W4315752686","https://openalex.org/W2080457830","https://openalex.org/W1819420704"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Determine":[1],"whether":[2],"adjuvant":[3,34,84,132,138,151,168,184,198,232],"chemotherapy":[4,85,139,152,185,199],"is":[5,25],"associated":[6,159,189,206],"with":[7,38,60,86,140,153,160,190,200,207,242],"a":[8,161,171,191,208],"survival":[9,117,163,192,210],"benefit":[10,164,211],"in":[11,212],"high":[12,73,178,224],"risk":[13,74,179,225],"T2-4a,":[14],"pathologically":[15,215],"node-negative":[16,216],"distal":[17,39,217],"esophageal":[18,40,62,218,246],"adenocarcinoma.":[19,247],"SUMMARY":[20],"OF":[21],"BACKGROUND":[22],"DATA:":[23],"There":[24],"minimal":[26],"literature":[27],"to":[28,56,115,166,240],"substantiate":[29],"the":[30,76,119],"NCCN":[31,182],"guidelines":[32],"recommending":[33],"therapy":[35,133,233],"for":[36],"patients":[37,59,125,176,241],"adenocarcinoma":[41,63],"and":[42,69,101,134,148,229],"no":[43,167],"pathologic":[44],"evidence":[45],"of":[46,83,174,221,223,231],"nodal":[47],"disease.":[48],"METHODS:":[49],"The":[50,90,227],"National":[51],"Cancer":[52],"Database":[53],"was":[54,93,97,112,157,186,204],"used":[55],"identify":[57],"adult":[58],"pT2-4aN0M0":[61,245],"who":[64,136],"underwent":[65],"definitive":[66],"surgery":[67],"(2004-2015)":[68],"had":[70],"characteristics":[71],"considered":[72],"by":[75,81,181],"NCCN.":[77],"Patients":[78],"were":[79],"stratified":[80],"receipt":[82],"or":[87,141,154,201],"without":[88,131,142,155,177,202],"radiation.":[89],"primary":[91],"outcome":[92],"overall":[94],"survival,":[95],"which":[96],"evaluated":[98],"using":[99],"Kaplan-Meier":[100],"multivariable":[102,149],"Cox":[103],"Proportional":[104],"Hazards":[105],"models.":[106],"A":[107],"1:1":[108],"propensity":[109],"score-matched":[110],"analysis":[111,173],"also":[113],"performed":[114],"compare":[116],"between":[118],"groups.":[120],"RESULTS:":[121],"Four":[122],"hundred":[123],"three":[124],"met":[126],"study":[127],"criteria:":[128],"313":[129],"(78%)":[130],"90":[135],"received":[137],"radiation":[143,156,203],"(22%).":[144],"In":[145,170,195],"both":[146],"unadjusted":[147],"analysis,":[150,197],"not":[158,187,205],"significant":[162,209],"compared":[165],"therapy.":[169],"subgroup":[172],"335":[175],"features":[180],"criteria,":[183],"independently":[188],"benefit.":[193],"CONCLUSION:":[194],"this":[196],"completely":[213,243],"resected,":[214],"adenocarcinoma,":[219],"independent":[220],"presence":[222],"characteristics.":[226],"risks":[228],"benefits":[230],"should":[234],"be":[235],"weighed":[236],"before":[237],"offering":[238],"it":[239],"resected":[244]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-04-03T00:00:00"}
