{"id":"https://openalex.org/W3013330718","doi":"https://doi.org/10.1016/j.cyto.2020.155058","title":"Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-\u03baB signaling pathway","display_name":"Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-\u03baB signaling pathway","publication_year":2020,"publication_date":"2020-03-26","ids":{"openalex":"https://openalex.org/W3013330718","doi":"https://doi.org/10.1016/j.cyto.2020.155058","mag":"3013330718","pmid":"https://pubmed.ncbi.nlm.nih.gov/32222695"},"language":"en","primary_location":{"id":"doi:10.1016/j.cyto.2020.155058","doi":"https://doi.org/10.1016/j.cyto.2020.155058","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cyto.2020.155058","pdf_url":null,"source":{"id":"https://openalex.org/S70396342","display_name":"Cytokine","issn_l":"1043-4666","issn":["1043-4666","1096-0023"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytokine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002669383","display_name":"Ke Yang","orcid":"https://orcid.org/0000-0002-1870-1134","observed_orcids":["https://orcid.org/0000-0002-1870-1134","https://orcid.org/0009-0000-4109-622X"]},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ke Yang","raw_affiliation_strings":["Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China","institution_ids":["https://openalex.org/I55712492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045835898","display_name":"Lianghui Zhan","orcid":"https://orcid.org/0000-0002-7938-8444","observed_orcids":["https://orcid.org/0000-0002-7938-8444"]},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lianghui Zhan","raw_affiliation_strings":["Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China","institution_ids":["https://openalex.org/I55712492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103225065","display_name":"Tingting Lu","orcid":"https://orcid.org/0000-0003-0768-9421","observed_orcids":["https://orcid.org/0000-0003-0768-9421"]},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tingting Lu","raw_affiliation_strings":["Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China","institution_ids":["https://openalex.org/I55712492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101668814","display_name":"Cong Zhou","orcid":"https://orcid.org/0000-0003-1875-6335","observed_orcids":["https://orcid.org/0000-0003-1875-6335"]},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cong Zhou","raw_affiliation_strings":["Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China","institution_ids":["https://openalex.org/I55712492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100408537","display_name":"Xue Chen","orcid":"https://orcid.org/0000-0001-5098-4616","observed_orcids":["https://orcid.org/0000-0001-5098-4616"]},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xue Chen","raw_affiliation_strings":["Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China","institution_ids":["https://openalex.org/I55712492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075688195","display_name":"Yingjie Dong","orcid":"https://orcid.org/0000-0002-6919-7927","observed_orcids":["https://orcid.org/0000-0002-6919-7927"]},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingjie Dong","raw_affiliation_strings":["Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China","institution_ids":["https://openalex.org/I55712492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089921461","display_name":"Guiyuan Lv","orcid":"https://orcid.org/0000-0003-2732-4905","observed_orcids":["https://orcid.org/0000-0003-2732-4905"]},"institutions":[{"id":"https://openalex.org/I114539943","display_name":"Zhejiang Chinese Medical University","ror":"https://ror.org/04epb4p87","country_code":"CN","type":"education","lineage":["https://openalex.org/I114539943"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guiyuan Lv","raw_affiliation_strings":["College of Pharmaceutical Science, No. 548, Binwen Road, Binjiang District, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China. Electronic address: lv.gy@263.net","College of Pharmaceutical Science, No. 548, Binwen Road, Binjiang District, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmaceutical Science, No. 548, Binwen Road, Binjiang District, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China. Electronic address: lv.gy@263.net","institution_ids":["https://openalex.org/I114539943"]},{"raw_affiliation_string":"College of Pharmaceutical Science, No. 548, Binwen Road, Binjiang District, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China","institution_ids":["https://openalex.org/I114539943"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005848875","display_name":"Suhong Chen","orcid":"https://orcid.org/0000-0001-8807-5071","observed_orcids":["https://orcid.org/0000-0001-8807-5071"]},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Suhong Chen","raw_affiliation_strings":["Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China. Electronic address: chensuhong@zjut.edu.cn","Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China. Electronic address: chensuhong@zjut.edu.cn","institution_ids":["https://openalex.org/I55712492"]},{"raw_affiliation_string":"Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, No. 18, Chaowang Road, Xiacheng District, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China","institution_ids":["https://openalex.org/I55712492"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5005848875","https://openalex.org/A5089921461"],"corresponding_institution_ids":["https://openalex.org/I114539943","https://openalex.org/I55712492"],"apc_list":{"value":3220,"currency":"USD","value_usd":3220},"apc_paid":null,"fwci":13.895,"has_fulltext":false,"cited_by_count":95,"citation_normalized_percentile":{"value":0.99411161,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"130","issue":null,"first_page":"155058","last_page":"155058"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13919","display_name":"Medicinal plant effects and applications","score":0.38040000200271606,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13919","display_name":"Medicinal plant effects and applications","score":0.38040000200271606,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.357699990272522,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13130","display_name":"Biological and pharmacological studies of plants","score":0.17970000207424164,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dendrobium-officinale-polysaccharide","display_name":"Dendrobium officinale polysaccharide","score":0.9259999990463257},{"id":"https://openalex.org/keywords/ethanol-induced-liver-injury","display_name":"ethanol-induced liver injury","score":0.8920000195503235},{"id":"https://openalex.org/keywords/hepatoprotective-effect","display_name":"hepatoprotection","score":0.8270000219345093},{"id":"https://openalex.org/keywords/tlr4-nf-kappab-signaling-pathway","display_name":"TLR4/NF-\u03baB signaling","score":0.9390000104904175},{"id":"https://openalex.org/keywords/alcoholic-liver-disease","display_name":"alcoholic liver disease","score":0.578000009059906},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.8009999990463257},{"id":"https://openalex.org/keywords/nlrp3-inflammasome","display_name":"NLRP3 inflammasome","score":0.9430000185966492},{"id":"https://openalex.org/keywords/caspase-1","display_name":"caspase-1","score":0.7950000166893005},{"id":"https://openalex.org/keywords/lo2-hepatocytes","display_name":"LO2 hepatocytes","score":0.7680000066757202},{"id":"https://openalex.org/keywords/herbal-polysaccharides","display_name":"herbal polysaccharides","score":0.7149999737739563}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.7416630387306213},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.7130244970321655},{"id":"https://openalex.org/C2776637226","wikidata":"https://www.wikidata.org/wiki/Q6658207","display_name":"Liver injury","level":2,"score":0.6673191785812378},{"id":"https://openalex.org/C2776070231","wikidata":"https://www.wikidata.org/wiki/Q14914098","display_name":"TLR4","level":3,"score":0.6199526786804199},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.49871230125427246},{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.48500630259513855},{"id":"https://openalex.org/C2777730290","wikidata":"https://www.wikidata.org/wiki/Q411114","display_name":"NF-\u03baB","level":3,"score":0.4654206931591034},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.443997323513031},{"id":"https://openalex.org/C2776219560","wikidata":"https://www.wikidata.org/wiki/Q133778","display_name":"Dendrobium","level":2,"score":0.41904953122138977},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.34034258127212524},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3172808289527893},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3142537772655487},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.30358341336250305},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2781578004360199},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26304274797439575},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.09058418869972229}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.cyto.2020.155058","doi":"https://doi.org/10.1016/j.cyto.2020.155058","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cyto.2020.155058","pdf_url":null,"source":{"id":"https://openalex.org/S70396342","display_name":"Cytokine","issn_l":"1043-4666","issn":["1043-4666","1096-0023"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytokine","raw_type":"journal-article"},{"id":"pmid:32222695","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32222695","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytokine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1039626795","display_name":null,"funder_award_id":"2017YFC1702200","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G1430435911","display_name":null,"funder_award_id":"81803761","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4652034678","display_name":null,"funder_award_id":"81673638","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4953766","display_name":null,"funder_award_id":"GY18034148004","funder_id":"https://openalex.org/F4320325031","funder_display_name":"Zhejiang University of Technology"},{"id":"https://openalex.org/G6201592700","display_name":null,"funder_award_id":"81874352","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6301753020","display_name":null,"funder_award_id":"ZJWR0102035","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8678215254","display_name":null,"funder_award_id":"2019M652144","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320325031","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W57492967","https://openalex.org/W216505837","https://openalex.org/W1922492370","https://openalex.org/W1967825083","https://openalex.org/W1968202620","https://openalex.org/W1973554941","https://openalex.org/W1975931952","https://openalex.org/W1986773261","https://openalex.org/W1988609484","https://openalex.org/W1989524688","https://openalex.org/W2000766305","https://openalex.org/W2009522235","https://openalex.org/W2021707548","https://openalex.org/W2031406182","https://openalex.org/W2038579078","https://openalex.org/W2042859664","https://openalex.org/W2043329777","https://openalex.org/W2057041123","https://openalex.org/W2064991226","https://openalex.org/W2067904003","https://openalex.org/W2070647828","https://openalex.org/W2103104072","https://openalex.org/W2108802512","https://openalex.org/W2137080115","https://openalex.org/W2144821195","https://openalex.org/W2145136979","https://openalex.org/W2149828808","https://openalex.org/W2206384930","https://openalex.org/W2266828950","https://openalex.org/W2272564146","https://openalex.org/W2416662732","https://openalex.org/W2474736177","https://openalex.org/W2522054313","https://openalex.org/W2588442940","https://openalex.org/W2593136873","https://openalex.org/W2756343284","https://openalex.org/W2767462141","https://openalex.org/W2770747629","https://openalex.org/W2802475344","https://openalex.org/W2895483326","https://openalex.org/W2897662939","https://openalex.org/W2965762087","https://openalex.org/W6745383383"],"related_works":["https://openalex.org/W7167260824","https://openalex.org/W4410775027","https://openalex.org/W2766023351","https://openalex.org/W4400979050","https://openalex.org/W4306174444","https://openalex.org/W2000766305","https://openalex.org/W3184625144","https://openalex.org/W2883197823","https://openalex.org/W4409566854","https://openalex.org/W4383501028"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-04-03T00:00:00"}