{"id":"https://openalex.org/W3012909151","doi":null,"title":"Core Clock Protein Bmal 1 Controls Reactive Oxygen Species Homeostasis And Oxidative Responses By Transregulating Prdx6 Expression","display_name":"Core Clock Protein Bmal 1 Controls Reactive Oxygen Species Homeostasis And Oxidative Responses By Transregulating Prdx6 Expression","publication_year":2019,"publication_date":"2019-07-22","ids":{"openalex":"https://openalex.org/W3012909151","mag":"3012909151"},"language":"en","primary_location":{"id":"mag:3012909151","doi":null,"is_oa":true,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2741658","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://iovs.arvojournals.org/article.aspx?articleid=2741658","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101836695","display_name":"Dhirendra P. Singh","orcid":"https://orcid.org/0000-0003-3311-2191","observed_orcids":["https://orcid.org/0000-0003-3311-2191"]},"institutions":[{"id":"https://openalex.org/I59130452","display_name":"University of Nebraska Medical Center","ror":"https://ror.org/00thqtb16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I59130452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dhirendra P. Singh","raw_affiliation_strings":["Ophthalmology and Visual Sciences, Univ of Neb Med Center, Omaha, Nebraska, United States"],"raw_orcid":"https://orcid.org/0000-0003-3311-2191","affiliations":[{"raw_affiliation_string":"Ophthalmology and Visual Sciences, Univ of Neb Med Center, Omaha, Nebraska, United States","institution_ids":["https://openalex.org/I59130452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072279870","display_name":"Eri Kubo","orcid":"https://orcid.org/0000-0001-6789-9311","observed_orcids":["https://orcid.org/0000-0001-6789-9311"]},"institutions":[{"id":"https://openalex.org/I16568816","display_name":"Kanazawa Medical University","ror":"https://ror.org/0535cbe18","country_code":"JP","type":"education","lineage":["https://openalex.org/I16568816"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eri Kubo","raw_affiliation_strings":["Ophthalmology, Kanazawa Medical University, Kanazawa, Ishikawa, Japan"],"raw_orcid":"https://orcid.org/0000-0001-6789-9311","affiliations":[{"raw_affiliation_string":"Ophthalmology, Kanazawa Medical University, Kanazawa, Ishikawa, Japan","institution_ids":["https://openalex.org/I16568816"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010780653","display_name":"Bhavana Chhunchha","orcid":"https://orcid.org/0000-0001-9613-8765","observed_orcids":["https://orcid.org/0000-0001-9613-8765"]},"institutions":[{"id":"https://openalex.org/I59130452","display_name":"University of Nebraska Medical Center","ror":"https://ror.org/00thqtb16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I59130452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bhavana Chhunchha","raw_affiliation_strings":["Ophthalmology and Visual Sciences, Univ of Neb Med Center, Omaha, Nebraska, United States"],"raw_orcid":"https://orcid.org/0000-0001-9613-8765","affiliations":[{"raw_affiliation_string":"Ophthalmology and Visual Sciences, Univ of Neb Med Center, Omaha, Nebraska, United States","institution_ids":["https://openalex.org/I59130452"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.2058106,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"60","issue":"9","first_page":"1127","last_page":"1127"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.017400000244379044,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bmal1","display_name":"Bmal1","score":0.9879999756813049},{"id":"https://openalex.org/keywords/reactive-oxygen-species-homeostasis","display_name":"reactive oxygen species homeostasis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/oxidative-stress-response","display_name":"oxidative stress response","score":0.9290000200271606},{"id":"https://openalex.org/keywords/peroxiredoxin-6","display_name":"peroxiredoxin 6","score":0.9879999756813049},{"id":"https://openalex.org/keywords/circadian-clock","display_name":"circadian clock","score":0.6830000281333923},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5630000233650208},{"id":"https://openalex.org/keywords/retinal-cells","display_name":"retinal cells","score":0.3479999899864197}],"concepts":[{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.6330020427703857},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6169583797454834},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.5214847326278687},{"id":"https://openalex.org/C2164484","wikidata":"https://www.wikidata.org/wiki/Q5170150","display_name":"Core (optical fiber)","level":2,"score":0.4970608055591583},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.49570930004119873},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.4451950192451477},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.41613635420799255},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3651975393295288},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15763705968856812},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11758232116699219},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.05303356051445007},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.040086060762405396}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3012909151","doi":null,"is_oa":true,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2741658","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null}],"best_oa_location":{"id":"mag:3012909151","doi":null,"is_oa":true,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2741658","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null},"sustainable_development_goals":[{"score":0.7246000170707703,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2917035648","https://openalex.org/W2934279985","https://openalex.org/W871678930","https://openalex.org/W2092251671","https://openalex.org/W3184185100","https://openalex.org/W7146266851","https://openalex.org/W4410249634","https://openalex.org/W2525945270","https://openalex.org/W4212777273","https://openalex.org/W4297858107"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2020-03-27T00:00:00"}