{"id":"https://openalex.org/W3012368465","doi":null,"title":"Expression of FANCD2 is associated with prognosis in patients with nasopharyngeal carcinoma.","display_name":"Expression of FANCD2 is associated with prognosis in patients with nasopharyngeal carcinoma.","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W3012368465","mag":"3012368465","pmid":"https://pubmed.ncbi.nlm.nih.gov/31934192","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6949855"},"language":"en","primary_location":{"id":"pmid:31934192","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31934192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of clinical and experimental pathology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6949855/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050485751","display_name":"Shengen Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3017480383","display_name":"Southwest Medical University","ror":"https://ror.org/00g2rqs52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3017480383"]},{"id":"https://openalex.org/I4210086248","display_name":"Affiliated Hospital of Southwest Medical University","ror":"https://ror.org/0014a0n68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengen Xu","raw_affiliation_strings":["Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China","institution_ids":["https://openalex.org/I3017480383","https://openalex.org/I4210086248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101833131","display_name":"Feipeng Zhao","orcid":"https://orcid.org/0009-0001-9224-2212","observed_orcids":["https://orcid.org/0009-0001-9224-2212","https://orcid.org/0000-0002-1522-6606"]},"institutions":[{"id":"https://openalex.org/I3017480383","display_name":"Southwest Medical University","ror":"https://ror.org/00g2rqs52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3017480383"]},{"id":"https://openalex.org/I4210086248","display_name":"Affiliated Hospital of Southwest Medical University","ror":"https://ror.org/0014a0n68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feipeng Zhao","raw_affiliation_strings":["Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China","institution_ids":["https://openalex.org/I3017480383","https://openalex.org/I4210086248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100527174","display_name":"Zhuoping Liang","orcid":"https://orcid.org/0000-0003-3366-1748","observed_orcids":["https://orcid.org/0000-0003-3366-1748","https://orcid.org/0000-0002-0420-8285"]},"institutions":[{"id":"https://openalex.org/I3017480383","display_name":"Southwest Medical University","ror":"https://ror.org/00g2rqs52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3017480383"]},{"id":"https://openalex.org/I4210086248","display_name":"Affiliated Hospital of Southwest Medical University","ror":"https://ror.org/0014a0n68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuoping Liang","raw_affiliation_strings":["Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China","institution_ids":["https://openalex.org/I3017480383","https://openalex.org/I4210086248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103012970","display_name":"Huajun Feng","orcid":"https://orcid.org/0000-0003-1347-5219","observed_orcids":["https://orcid.org/0000-0003-1347-5219","https://orcid.org/0000-0002-3974-6534"]},"institutions":[{"id":"https://openalex.org/I3017480383","display_name":"Southwest Medical University","ror":"https://ror.org/00g2rqs52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3017480383"]},{"id":"https://openalex.org/I4210086248","display_name":"Affiliated Hospital of Southwest Medical University","ror":"https://ror.org/0014a0n68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huajun Feng","raw_affiliation_strings":["Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China","institution_ids":["https://openalex.org/I3017480383","https://openalex.org/I4210086248"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yilin Bao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3017480383","display_name":"Southwest Medical University","ror":"https://ror.org/00g2rqs52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3017480383"]},{"id":"https://openalex.org/I4210086248","display_name":"Affiliated Hospital of Southwest Medical University","ror":"https://ror.org/0014a0n68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yilin Bao","raw_affiliation_strings":["Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China","institution_ids":["https://openalex.org/I3017480383","https://openalex.org/I4210086248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067810193","display_name":"Wei Xu","orcid":"https://orcid.org/0000-0002-1513-9609","observed_orcids":["https://orcid.org/0000-0002-1513-9609"]},"institutions":[{"id":"https://openalex.org/I3017480383","display_name":"Southwest Medical University","ror":"https://ror.org/00g2rqs52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3017480383"]},{"id":"https://openalex.org/I4210086248","display_name":"Affiliated Hospital of Southwest Medical University","ror":"https://ror.org/0014a0n68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Xu","raw_affiliation_strings":["Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China","institution_ids":["https://openalex.org/I3017480383","https://openalex.org/I4210086248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087898022","display_name":"Chong Zhao","orcid":"https://orcid.org/0000-0003-3271-5783","observed_orcids":["https://orcid.org/0000-0003-3271-5783"]},"institutions":[{"id":"https://openalex.org/I3017480383","display_name":"Southwest Medical University","ror":"https://ror.org/00g2rqs52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3017480383"]},{"id":"https://openalex.org/I4210086248","display_name":"Affiliated Hospital of Southwest Medical University","ror":"https://ror.org/0014a0n68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chong Zhao","raw_affiliation_strings":["Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China","institution_ids":["https://openalex.org/I3017480383","https://openalex.org/I4210086248"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069760869","display_name":"Gang Qin","orcid":"https://orcid.org/0000-0002-3495-0456","observed_orcids":["https://orcid.org/0000-0002-3495-0456"]},"institutions":[{"id":"https://openalex.org/I3017480383","display_name":"Southwest Medical University","ror":"https://ror.org/00g2rqs52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3017480383"]},{"id":"https://openalex.org/I4210086248","display_name":"Affiliated Hospital of Southwest Medical University","ror":"https://ror.org/0014a0n68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gang Qin","raw_affiliation_strings":["Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Southwest Medical College Luzhou, Sichuan Province, China","institution_ids":["https://openalex.org/I3017480383","https://openalex.org/I4210086248"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.8182,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.82516692,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"12","issue":"9","first_page":"3465","last_page":"3473"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fancd2","display_name":"FANCD2","score":1.0},{"id":"https://openalex.org/keywords/nasopharyngeal-carcinoma","display_name":"nasopharyngeal carcinoma","score":1.0},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.7059999704360962},{"id":"https://openalex.org/keywords/cervical-lymph-node-metastasis","display_name":"cervical lymph node metastasis","score":0.8149999976158142},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.9520000219345093},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.9909999966621399},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8410000205039978},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.6510000228881836},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.6589999794960022}],"concepts":[{"id":"https://openalex.org/C2776653068","wikidata":"https://www.wikidata.org/wiki/Q17927069","display_name":"FANCD2","level":5,"score":0.8288154602050781},{"id":"https://openalex.org/C2778997737","wikidata":"https://www.wikidata.org/wiki/Q1693598","display_name":"Nasopharyngeal carcinoma","level":3,"score":0.8227595090866089},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5490860342979431},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.45951592922210693},{"id":"https://openalex.org/C2778549279","wikidata":"https://www.wikidata.org/wiki/Q962200","display_name":"Cervical lymph nodes","level":4,"score":0.45405155420303345},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.42098334431648254},{"id":"https://openalex.org/C2778124228","wikidata":"https://www.wikidata.org/wiki/Q845779","display_name":"Fanconi anemia","level":4,"score":0.4088185429573059},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3786235451698303},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.37418127059936523},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3697303533554077},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.36870643496513367},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2879957854747772},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.20299050211906433},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.10736808180809021},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.07518956065177917},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:31934192","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31934192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of clinical and experimental pathology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6949855","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6949855/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Pathol","raw_type":"Text"},{"id":"mag:3012368465","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31934192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6949855","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6949855/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Pathol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W117866975","https://openalex.org/W1987871280","https://openalex.org/W1991841649","https://openalex.org/W1992974293","https://openalex.org/W2008207745","https://openalex.org/W2019219335","https://openalex.org/W2024073282","https://openalex.org/W2046483552","https://openalex.org/W2048020441","https://openalex.org/W2065329309","https://openalex.org/W2088794995","https://openalex.org/W2090378429","https://openalex.org/W2106713597","https://openalex.org/W2110938265","https://openalex.org/W2112158920","https://openalex.org/W2114358685","https://openalex.org/W2115167146","https://openalex.org/W2121521881","https://openalex.org/W2125905031","https://openalex.org/W2130019054","https://openalex.org/W2141868357","https://openalex.org/W2148593237","https://openalex.org/W2161854614","https://openalex.org/W2164682636","https://openalex.org/W2917837889"],"related_works":["https://openalex.org/W4283765171","https://openalex.org/W2088863055","https://openalex.org/W2351377119","https://openalex.org/W2146103295","https://openalex.org/W2010629909","https://openalex.org/W2128844816","https://openalex.org/W2170657019","https://openalex.org/W2372812097","https://openalex.org/W2535345601","https://openalex.org/W2354913744"],"abstract_inverted_index":{",":[0],"stage":[1],"III-IV":[2],"NPC":[3,37],"tissues":[4,27],"with":[5,16,18,78],"a":[6,44,100],"duration":[7],"of":[8,60,87,92,109],"disease":[9],"longer":[10],"than":[11,48,67],"6":[12],"months.":[13],"Moreover,":[14],"compared":[15],"patients":[17,29,38,50],"cervical":[19,31,83],"lymph":[20,32,84],"node":[21,33,85],"metastases,":[22],"FANCD2":[23,75,94,97],"was":[24,64,69],"elevated":[25],"in":[26,39,51,70],"from":[28],"without":[30],"metastases.":[34],"Furthermore,":[35],"the":[36,40,49,52,56,61,71,79,90,104],"high-FANCD2-expression":[41],"group":[42,63],"exhibited":[43],"higher":[45],"recurrence":[46],"rate":[47,59],"low-FANCD2-expression":[53],"group.":[54,73],"Finally,":[55],"disease-free":[57],"survival":[58],"high-expression":[62],"significantly":[65],"lower":[66],"it":[68],"low-expression":[72],"Therefore,":[74],"is":[76,95],"associated":[77],"occurrence,":[80],"differentiation,":[81],"and":[82,107],"metastasis":[86],"NPC.":[88,110],"With":[89],"development":[91],"NPC,":[93],"down-regulated.":[96],"may":[98],"be":[99],"molecular":[101],"marker":[102],"for":[103],"early":[105],"diagnosis":[106],"prognosis":[108]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-03-23T00:00:00"}