{"id":"https://openalex.org/W3012347787","doi":"https://doi.org/10.1186/s13063-019-4029-5","title":"Examining the benefits and harms of Alzheimer\u2019s disease screening for family members of older adults: study protocol for a randomized controlled trial","display_name":"Examining the benefits and harms of Alzheimer\u2019s disease screening for family members of older adults: study protocol for a randomized controlled trial","publication_year":2020,"publication_date":"2020-02-19","ids":{"openalex":"https://openalex.org/W3012347787","doi":"https://doi.org/10.1186/s13063-019-4029-5","mag":"3012347787","pmid":"https://pubmed.ncbi.nlm.nih.gov/32075686","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7031904"},"language":"en","primary_location":{"id":"doi:10.1186/s13063-019-4029-5","doi":"https://doi.org/10.1186/s13063-019-4029-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13063-019-4029-5","pdf_url":"https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-019-4029-5","source":{"id":"https://openalex.org/S109512841","display_name":"Trials","issn_l":"1745-6215","issn":["1745-6215"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trials","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-019-4029-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005942463","display_name":"Nicole R. Fowler","orcid":"https://orcid.org/0000-0002-6465-0008","observed_orcids":["https://orcid.org/0000-0002-6465-0008"]},"institutions":[{"id":"https://openalex.org/I1324682000","display_name":"Regenstrief Institute","ror":"https://ror.org/05f2ywb48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1324682000"]},{"id":"https://openalex.org/I4210112010","display_name":"Indiana Clinical and Translational Sciences Institute","ror":"https://ror.org/022t7q367","country_code":"US","type":"government","lineage":["https://openalex.org/I4210112010"]},{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nicole R. Fowler","raw_affiliation_strings":["Center for Health Innovation and Implementation Science, Indiana Clinical and Translational Science Institute, Indianapolis, IN, 46202, USA. fowlern@iupui.edu","Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. fowlern@iupui.edu","Indiana University Center for Aging Research, Indianapolis, IN, 46202, USA. fowlern@iupui.edu","Regenstrief Institute, Inc., Indianapolis, IN, 46202, USA. fowlern@iupui.edu","Center for Health Innovation and Implementation Science, Indiana Clinical and Translational Science Institute, Indianapolis, USA","Department of Medicine, Indiana University School of Medicine, Indianapolis, USA","Indiana University Center for Aging Research, Indianapolis, USA","Regenstrief Institute, Inc., Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Health Innovation and Implementation Science, Indiana Clinical and Translational Science Institute, Indianapolis, IN, 46202, USA. fowlern@iupui.edu","institution_ids":["https://openalex.org/I4210112010"]},{"raw_affiliation_string":"Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. fowlern@iupui.edu","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130","https://openalex.org/I55769427"]},{"raw_affiliation_string":"Indiana University Center for Aging Research, Indianapolis, IN, 46202, USA. fowlern@iupui.edu","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I55769427"]},{"raw_affiliation_string":"Regenstrief Institute, Inc., Indianapolis, IN, 46202, USA. fowlern@iupui.edu","institution_ids":["https://openalex.org/I1324682000"]},{"raw_affiliation_string":"Center for Health Innovation and Implementation Science, Indiana Clinical and Translational Science Institute, Indianapolis, USA","institution_ids":["https://openalex.org/I4210112010"]},{"raw_affiliation_string":"Department of Medicine, Indiana University School of Medicine, Indianapolis, USA","institution_ids":["https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Indiana University Center for Aging Research, Indianapolis, USA","institution_ids":["https://openalex.org/I4388446366"]},{"raw_affiliation_string":"Regenstrief Institute, Inc., Indianapolis, USA","institution_ids":["https://openalex.org/I1324682000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089270296","display_name":"Katharine J. Head","orcid":"https://orcid.org/0000-0001-8946-1716","observed_orcids":["https://orcid.org/0000-0001-8946-1716"]},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katharine J. Head","raw_affiliation_strings":["Department of Communication Studies, Indiana University-Purdue University Indianapolis, Indianapolis, IN, 46202, USA","Department of Communication Studies, Indiana University-Purdue University Indianapolis, Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Communication Studies, Indiana University-Purdue University Indianapolis, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I55769427"]},{"raw_affiliation_string":"Department of Communication Studies, Indiana University-Purdue University Indianapolis, Indianapolis, USA","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012541607","display_name":"Anthony J. Perkins","orcid":"https://orcid.org/0000-0003-1278-5397","observed_orcids":["https://orcid.org/0000-0003-1278-5397"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony J. Perkins","raw_affiliation_strings":["Department of Biostatistics, Indiana University School of Medicine & Richard M. Fairbanks School of Public Health, Indianapolis, IN, 46202, USA","Department of Biostatistics, Indiana University School of Medicine & Richard M. Fairbanks School of Public Health, Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Indiana University School of Medicine & Richard M. Fairbanks School of Public Health, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Department of Biostatistics, Indiana University School of Medicine & Richard M. Fairbanks School of Public Health, Indianapolis, USA","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039635718","display_name":"Sujuan Gao","orcid":"https://orcid.org/0000-0002-6741-6380","observed_orcids":["https://orcid.org/0000-0002-6741-6380","https://orcid.org/0000-0002-8807-9248"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sujuan Gao","raw_affiliation_strings":["Department of Biostatistics, Indiana University School of Medicine & Richard M. Fairbanks School of Public Health, Indianapolis, IN, 46202, USA","Department of Biostatistics, Indiana University School of Medicine & Richard M. Fairbanks School of Public Health, Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Indiana University School of Medicine & Richard M. Fairbanks School of Public Health, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Department of Biostatistics, Indiana University School of Medicine & Richard M. Fairbanks School of Public Health, Indianapolis, USA","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022515998","display_name":"Christopher M. Callahan","orcid":"https://orcid.org/0000-0002-4617-6672","observed_orcids":["https://orcid.org/0000-0002-4617-6672"]},"institutions":[{"id":"https://openalex.org/I1324682000","display_name":"Regenstrief Institute","ror":"https://ror.org/05f2ywb48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1324682000"]},{"id":"https://openalex.org/I4387930283","display_name":"Eskenazi Health","ror":"https://ror.org/0046t1019","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210130353","https://openalex.org/I4387930232","https://openalex.org/I4387930283"]},{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher M. Callahan","raw_affiliation_strings":["Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA","Eskenazi Health, Indianapolis, IN, 46202, USA","Indiana University Center for Aging Research, Indianapolis, IN, 46202, USA","Regenstrief Institute, Inc., Indianapolis, IN, 46202, USA","Department of Medicine, Indiana University School of Medicine, Indianapolis, USA","Eskenazi Health, Indianapolis, USA","Indiana University Center for Aging Research, Indianapolis, USA","Regenstrief Institute, Inc., Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Eskenazi Health, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I4387930283"]},{"raw_affiliation_string":"Indiana University Center for Aging Research, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I4388446366"]},{"raw_affiliation_string":"Regenstrief Institute, Inc., Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I1324682000"]},{"raw_affiliation_string":"Department of Medicine, Indiana University School of Medicine, Indianapolis, USA","institution_ids":["https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Eskenazi Health, Indianapolis, USA","institution_ids":["https://openalex.org/I4387930283"]},{"raw_affiliation_string":"Indiana University Center for Aging Research, Indianapolis, USA","institution_ids":["https://openalex.org/I4388446366"]},{"raw_affiliation_string":"Regenstrief Institute, Inc., Indianapolis, USA","institution_ids":["https://openalex.org/I1324682000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009224045","display_name":"Tamilyn Bakas","orcid":"https://orcid.org/0000-0002-3235-5012","observed_orcids":["https://orcid.org/0000-0002-3235-5012"]},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tamilyn Bakas","raw_affiliation_strings":["College of Nursing, University of Cincinnati, Cincinnati, OH, 45219, USA","College of Nursing, University of Cincinnati, Cincinnati, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Nursing, University of Cincinnati, Cincinnati, OH, 45219, USA","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"College of Nursing, University of Cincinnati, Cincinnati, USA","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089257624","display_name":"Shelley Suarez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1324682000","display_name":"Regenstrief Institute","ror":"https://ror.org/05f2ywb48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1324682000"]},{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shelley D. Suarez","raw_affiliation_strings":["Indiana University Center for Aging Research, Indianapolis, IN, 46202, USA","Regenstrief Institute, Inc., Indianapolis, IN, 46202, USA","Indiana University Center for Aging Research, Indianapolis, USA","Regenstrief Institute, Inc., Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University Center for Aging Research, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I4388446366"]},{"raw_affiliation_string":"Regenstrief Institute, Inc., Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I1324682000"]},{"raw_affiliation_string":"Indiana University Center for Aging Research, Indianapolis, USA","institution_ids":["https://openalex.org/I4388446366"]},{"raw_affiliation_string":"Regenstrief Institute, Inc., Indianapolis, USA","institution_ids":["https://openalex.org/I1324682000"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019055956","display_name":"Malaz A. Boustani","orcid":"https://orcid.org/0000-0003-0330-677X","observed_orcids":["https://orcid.org/0000-0003-0330-677X"]},"institutions":[{"id":"https://openalex.org/I1324682000","display_name":"Regenstrief Institute","ror":"https://ror.org/05f2ywb48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1324682000"]},{"id":"https://openalex.org/I4210112010","display_name":"Indiana Clinical and Translational Sciences Institute","ror":"https://ror.org/022t7q367","country_code":"US","type":"government","lineage":["https://openalex.org/I4210112010"]},{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Malaz A. Boustani","raw_affiliation_strings":["Center for Health Innovation and Implementation Science, Indiana Clinical and Translational Science Institute, Indianapolis, IN, 46202, USA","Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA","Indiana University Center for Aging Research, Indianapolis, IN, 46202, USA","Regenstrief Institute, Inc., Indianapolis, IN, 46202, USA","Center for Health Innovation and Implementation Science, Indiana Clinical and Translational Science Institute, Indianapolis, USA","Department of Medicine, Indiana University School of Medicine, Indianapolis, USA","Indiana University Center for Aging Research, Indianapolis, USA","Regenstrief Institute, Inc., Indianapolis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Health Innovation and Implementation Science, Indiana Clinical and Translational Science Institute, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I4210112010"]},{"raw_affiliation_string":"Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Indiana University Center for Aging Research, Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I4388446366"]},{"raw_affiliation_string":"Regenstrief Institute, Inc., Indianapolis, IN, 46202, USA","institution_ids":["https://openalex.org/I1324682000"]},{"raw_affiliation_string":"Center for Health Innovation and Implementation Science, Indiana Clinical and Translational Science Institute, Indianapolis, USA","institution_ids":["https://openalex.org/I4210112010"]},{"raw_affiliation_string":"Department of Medicine, Indiana University School of Medicine, Indianapolis, USA","institution_ids":["https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Indiana University Center for Aging Research, Indianapolis, USA","institution_ids":["https://openalex.org/I4388446366"]},{"raw_affiliation_string":"Regenstrief Institute, Inc., Indianapolis, USA","institution_ids":["https://openalex.org/I1324682000"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5005942463"],"corresponding_institution_ids":["https://openalex.org/I1324682000","https://openalex.org/I4210112010","https://openalex.org/I4388446366","https://openalex.org/I4394709130","https://openalex.org/I55769427"],"apc_list":{"value":2190,"currency":"USD","value_usd":2190},"apc_paid":{"value":2190,"currency":"USD","value_usd":2190},"fwci":1.4505,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.7937394,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"21","issue":"1","first_page":"202","last_page":"202"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10177","display_name":"Palliative Care and End-of-Life Issues","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13111","display_name":"Nursing care and research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3611","display_name":"Pharmacy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease-and-related-dementias","display_name":"Alzheimer's disease and related dementias","score":0.9229999780654907},{"id":"https://openalex.org/keywords/dementia-screening","display_name":"dementia screening","score":0.921999990940094},{"id":"https://openalex.org/keywords/family-caregivers","display_name":"family caregivers","score":0.9710000157356262},{"id":"https://openalex.org/keywords/dyadic-relationships","display_name":"dyads","score":0.5799999833106995},{"id":"https://openalex.org/keywords/early-detection","display_name":"early detection","score":0.5879999995231628},{"id":"https://openalex.org/keywords/diagnostic-assessment","display_name":"diagnostic assessment","score":0.5989999771118164},{"id":"https://openalex.org/keywords/caregiver-quality-of-life","display_name":"caregiver quality of life","score":0.7319999933242798},{"id":"https://openalex.org/keywords/depressive-symptoms","display_name":"depressive symptoms","score":0.8679999709129333},{"id":"https://openalex.org/keywords/anxiety-symptoms","display_name":"anxiety symptoms","score":0.8999999761581421},{"id":"https://openalex.org/keywords/caregiver-preparedness","display_name":"caregiver preparedness","score":0.7599999904632568},{"id":"https://openalex.org/keywords/self-efficacy","display_name":"self-efficacy","score":0.9210000038146973},{"id":"https://openalex.org/keywords/primary-care","display_name":"primary care","score":0.3479999899864197}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8033368587493896},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6492689847946167},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.6418812870979309},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.47712138295173645},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.4555782079696655},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4409126043319702},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.4141582250595093},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.4064643681049347},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.3701649308204651},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.33313512802124023},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.12543022632598877},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000223","descriptor_name":"Adaptation, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008603","descriptor_name":"Mental Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017028","descriptor_name":"Caregivers","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D020377","descriptor_name":"Self Efficacy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1186/s13063-019-4029-5","doi":"https://doi.org/10.1186/s13063-019-4029-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13063-019-4029-5","pdf_url":"https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-019-4029-5","source":{"id":"https://openalex.org/S109512841","display_name":"Trials","issn_l":"1745-6215","issn":["1745-6215"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trials","raw_type":"journal-article"},{"id":"doi:10.21203/rs.2.10296/v1","doi":"https://doi.org/10.21203/rs.2.10296/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.2.10296/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"doi:10.21203/rs.2.10296/v2","doi":"https://doi.org/10.21203/rs.2.10296/v2","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.2.10296/v2","pdf_url":"https://www.researchsquare.com/article/rs-1324/v2.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:7031904","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7031904","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trials","raw_type":"Text"},{"id":"pmid:32075686","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32075686","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trials","raw_type":"Clinical Trial Protocol"},{"id":"pmh:oai:doaj.org/article:1fe916a57c8644bc92219a8b4d98782d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/1fe916a57c8644bc92219a8b4d98782d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Trials, Vol 21, Iss 1, Pp 1-13 (2020)","raw_type":"article"},{"id":"pmh:oai:scholarworks.indianapolis.iu.edu:1805/22543","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1805/22543","pdf_url":null,"source":{"id":"https://openalex.org/S4306400987","display_name":"IUScholarWorks (Indiana University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I592451","host_organization_name":"Indiana University","host_organization_lineage":["https://openalex.org/I592451"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PMC","raw_type":"Article"},{"id":"pmh:oai:scholarworks.iupui.edu:1805/22543","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1805/22543","pdf_url":null,"source":{"id":"https://openalex.org/S4306402593","display_name":"Purdue University Indianapolis (Indiana University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I592451","host_organization_name":"Indiana University","host_organization_lineage":["https://openalex.org/I592451"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PMC","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/s13063-019-4029-5","doi":"https://doi.org/10.1186/s13063-019-4029-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13063-019-4029-5","pdf_url":"https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-019-4029-5","source":{"id":"https://openalex.org/S109512841","display_name":"Trials","issn_l":"1745-6215","issn":["1745-6215"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trials","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/study-protocol","display_name":"Study Protocol"}],"awards":[{"id":"https://openalex.org/G5237670153","display_name":"The Caregiver Outcomes of Alzheimer's Disease Screening (COADS) Trial","funder_award_id":"R01AG056325","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3012347787.pdf","grobid_xml":"https://content.openalex.org/works/W3012347787.grobid-xml"},"referenced_works_count":97,"referenced_works":["https://openalex.org/W23419774","https://openalex.org/W83859141","https://openalex.org/W1492075988","https://openalex.org/W1493773294","https://openalex.org/W1503477087","https://openalex.org/W1516053160","https://openalex.org/W1548478006","https://openalex.org/W1549090036","https://openalex.org/W1553544812","https://openalex.org/W1556698056","https://openalex.org/W1571669352","https://openalex.org/W1580581534","https://openalex.org/W1604295436","https://openalex.org/W1734351159","https://openalex.org/W1804909554","https://openalex.org/W1827460551","https://openalex.org/W1964755344","https://openalex.org/W1966402680","https://openalex.org/W1969621457","https://openalex.org/W1976981274","https://openalex.org/W1978023680","https://openalex.org/W1978374932","https://openalex.org/W1979271872","https://openalex.org/W1983749671","https://openalex.org/W1985329916","https://openalex.org/W1993968272","https://openalex.org/W1995422036","https://openalex.org/W1996152250","https://openalex.org/W1998803029","https://openalex.org/W2002767860","https://openalex.org/W2003746742","https://openalex.org/W2017215880","https://openalex.org/W2021582746","https://openalex.org/W2027365236","https://openalex.org/W2029396355","https://openalex.org/W2029421651","https://openalex.org/W2032698104","https://openalex.org/W2033506598","https://openalex.org/W2037377025","https://openalex.org/W2037761304","https://openalex.org/W2043012762","https://openalex.org/W2043224889","https://openalex.org/W2043283106","https://openalex.org/W2043705607","https://openalex.org/W2044758663","https://openalex.org/W2049155331","https://openalex.org/W2049265876","https://openalex.org/W2054831782","https://openalex.org/W2055516844","https://openalex.org/W2055531721","https://openalex.org/W2056830272","https://openalex.org/W2063319119","https://openalex.org/W2069867933","https://openalex.org/W2071068165","https://openalex.org/W2071583704","https://openalex.org/W2075951409","https://openalex.org/W2084906010","https://openalex.org/W2088354677","https://openalex.org/W2098631199","https://openalex.org/W2098915901","https://openalex.org/W2099556509","https://openalex.org/W2104053472","https://openalex.org/W2117195115","https://openalex.org/W2122196056","https://openalex.org/W2122522567","https://openalex.org/W2123979895","https://openalex.org/W2127635525","https://openalex.org/W2132396002","https://openalex.org/W2138375704","https://openalex.org/W2146995083","https://openalex.org/W2147221534","https://openalex.org/W2149721689","https://openalex.org/W2156000474","https://openalex.org/W2161341729","https://openalex.org/W2161719719","https://openalex.org/W2165937982","https://openalex.org/W2166487292","https://openalex.org/W2168512802","https://openalex.org/W2170347613","https://openalex.org/W2170793844","https://openalex.org/W2171283966","https://openalex.org/W2253311584","https://openalex.org/W2280835007","https://openalex.org/W2284050284","https://openalex.org/W2313407065","https://openalex.org/W2316166777","https://openalex.org/W2326956023","https://openalex.org/W2334182717","https://openalex.org/W2414725059","https://openalex.org/W2480680997","https://openalex.org/W2777250141","https://openalex.org/W2796020505","https://openalex.org/W4231841362","https://openalex.org/W4245692949","https://openalex.org/W4292806894","https://openalex.org/W6637684716","https://openalex.org/W6823832311"],"related_works":["https://openalex.org/W7154983621","https://openalex.org/W6958220081","https://openalex.org/W2539341571","https://openalex.org/W2991026540","https://openalex.org/W7117475933","https://openalex.org/W7133343926","https://openalex.org/W2103066715","https://openalex.org/W2526852165","https://openalex.org/W2104053472","https://openalex.org/W3120557568"],"abstract_inverted_index":{"BACKGROUND:":[0],"Multiple":[1],"national":[2,18],"expert":[3],"panels":[4],"have":[5],"identified":[6],"early":[7,339],"detection":[8,340],"of":[9,57,68,86,98,136,146,165,200,202,237,259,295,298],"Alzheimer's":[10,69,328],"disease":[11],"and":[12,43,104,134,182,185,209,215,222,227,239,245,252,255,265,302,305,332,338],"related":[13],"dementias":[14],"(ADRD)":[15],"as":[16],"a":[17,74,144,174],"priority.":[19],"However,":[20],"the":[21,41,50,55,81,96,124,137,152,166,186,198,203,231,235,257,271,288,323,330],"United":[22],"States":[23],"Preventive":[24],"Services":[25],"Task":[26],"Force":[27],"(USPSTF)":[28],"does":[29],"not":[30],"currently":[31],"support":[32],"screening":[33,59,88,131,138,159,167,269,276,289,337],"for":[34,52,101,149,179,262,308],"ADRD":[35,58,87,107,130,158,268,336],"in":[36,287],"primary":[37,207],"care":[38,177],"given":[39],"that":[40,78,285],"risks":[42],"benefits":[44,83],"are":[45],"unknown.":[46],"The":[47,65,193],"USPSTF":[48,331],"stresses":[49],"need":[51],"research":[53],"examining":[54],"impact":[56],"on":[60,89,347],"family":[61,90,204,210,246],"caregiver":[62],"outcomes.":[63],"METHODS:":[64],"Caregiver":[66],"Outcomes":[67],"Disease":[70],"Screening":[71,280],"(COADS)":[72],"is":[73],"randomized":[75,117,274],"controlled":[76],"trial":[77,195,232],"will":[79,93,110,115,128,156,189,196,233,291,320],"examine":[80,234],"potential":[82,183],"or":[84],"harms":[85],"caregivers.":[91],"It":[92],"also":[94],"compare":[95,256],"effectiveness":[97,258],"two":[99,260,272],"strategies":[100,261],"diagnostic":[102,150,180,263],"evaluation":[103,181,264],"management":[105,266],"after":[106,267],"screening.":[108,192],"COADS":[109,194],"enroll":[111],"1800":[112],"dyads":[113],"who":[114],"be":[116],"into":[118],"three":[119],"groups":[120,273],"(n":[121],"=":[122],"600/group):":[123],"'Screening":[125,153],"Only'":[126],"group":[127,155,188],"receive":[129,157,190],"at":[132,160,220,223,248,313],"baseline":[133,161,221],"disclosure":[135,164],"results,":[139,168],"with":[140,163,169,310],"positive-screen":[141,170],"participants":[142,171],"receiving":[143],"list":[145],"local":[147],"resources":[148],"follow-up;":[151],"Plus'":[154],"coupled":[162],"referred":[172],"to":[173,275,326],"dementia":[175],"collaborative":[176],"program":[178],"care;":[184],"control":[187],"no":[191],"measure":[197],"quality":[199,297],"life":[201],"member":[205,211],"(the":[206,217],"outcome)":[208],"mood,":[212],"anxiety,":[213],"preparedness":[214],"self-efficacy":[216,312],"secondary":[218],"outcomes)":[219],"6,":[224,249],"12,":[225,250],"18":[226,251],"24":[228,253,314],"months.":[229,315],"Additionally,":[230],"congruence":[236],"depressive":[238,301],"anxiety":[240,303],"symptoms":[241],"between":[242,270],"older":[243],"adults":[244],"members":[247],"months":[254],"(Screening":[277],"Only":[278],"versus":[279],"Plus).":[281],"DISCUSSION:":[282],"We":[283],"hypothesize":[284],"caregivers":[286],"arms":[290],"express":[292],"higher":[293,311],"levels":[294],"health-related":[296],"life,":[299],"lower":[300],"symptoms,":[304],"better":[306],"preparation":[307],"caregiving":[309],"Results":[316],"from":[317],"this":[318],"study":[319],"directly":[321],"inform":[322],"National":[324],"Plan":[325],"Address":[327],"Disease,":[329],"other":[333],"organizations":[334],"regarding":[335],"policies.":[341],"TRIAL":[342],"REGISTRATION:":[343],"ClinicalTrials.gov,":[344],"NCT03300180.":[345],"Registered":[346],"3":[348],"October.":[349]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2020-03-23T00:00:00"}