{"id":"https://openalex.org/W3011354367","doi":"https://doi.org/10.1097/mnm.0000000000001175","title":"Burden of metastatic bone disease measured on 18F-NaF PET/computed tomography studies as a prognostic indicator in patients with medullary thyroid cancer","display_name":"Burden of metastatic bone disease measured on 18F-NaF PET/computed tomography studies as a prognostic indicator in patients with medullary thyroid cancer","publication_year":2020,"publication_date":"2020-03-18","ids":{"openalex":"https://openalex.org/W3011354367","doi":"https://doi.org/10.1097/mnm.0000000000001175","mag":"3011354367","pmid":"https://pubmed.ncbi.nlm.nih.gov/32187160"},"language":"en","primary_location":{"id":"doi:10.1097/mnm.0000000000001175","doi":"https://doi.org/10.1097/mnm.0000000000001175","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mnm.0000000000001175","pdf_url":null,"source":{"id":"https://openalex.org/S108023290","display_name":"Nuclear Medicine Communications","issn_l":"0143-3636","issn":["0143-3636","1473-5628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear Medicine Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088002441","display_name":"Cristina Emiko Ueda","orcid":"https://orcid.org/0000-0003-0936-0670","observed_orcids":["https://orcid.org/0000-0003-0936-0670"]},"institutions":[{"id":"https://openalex.org/I4210088998","display_name":"Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo","ror":"https://ror.org/005vqqr19","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210088998"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cristina E. Ueda","raw_affiliation_strings":["Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)","institution_ids":["https://openalex.org/I4210088998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074217620","display_name":"Paulo Schiavom Duarte","orcid":"https://orcid.org/0000-0003-4517-4410","observed_orcids":["https://orcid.org/0000-0003-4517-4410"]},"institutions":[{"id":"https://openalex.org/I4210088998","display_name":"Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo","ror":"https://ror.org/005vqqr19","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210088998"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Paulo S. Duarte","raw_affiliation_strings":["Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)","institution_ids":["https://openalex.org/I4210088998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072532547","display_name":"Luciana Audi Castroneves","orcid":"https://orcid.org/0000-0002-2482-4675","observed_orcids":["https://orcid.org/0000-0002-2482-4675"]},"institutions":[{"id":"https://openalex.org/I4210088998","display_name":"Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo","ror":"https://ror.org/005vqqr19","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210088998"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luciana A. de Castroneves","raw_affiliation_strings":["Division of Endocrinology, S\u00e3o Paulo Cancer Institute (ICESP)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, S\u00e3o Paulo Cancer Institute (ICESP)","institution_ids":["https://openalex.org/I4210088998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109452997","display_name":"Jos\u00e9 Fl\u00e1vio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210088998","display_name":"Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo","ror":"https://ror.org/005vqqr19","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210088998"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Fl\u00e1vio","raw_affiliation_strings":["Division of Endocrinology, S\u00e3o Paulo Cancer Institute (ICESP)","Division of Nuclear Medicine, Department of Radiology and Oncology, Medical School of University of S\u00e3o Paulo (FMUSP), S\u00e3o Paulo, Brazil","Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, S\u00e3o Paulo Cancer Institute (ICESP)","institution_ids":["https://openalex.org/I4210088998"]},{"raw_affiliation_string":"Division of Nuclear Medicine, Department of Radiology and Oncology, Medical School of University of S\u00e3o Paulo (FMUSP), S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]},{"raw_affiliation_string":"Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)","institution_ids":["https://openalex.org/I4210088998"]}]},{"author_position":"middle","author":{"id":null,"display_name":"G. Marin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088998","display_name":"Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo","ror":"https://ror.org/005vqqr19","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210088998"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"G. Marin","raw_affiliation_strings":["Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)","institution_ids":["https://openalex.org/I4210088998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001973045","display_name":"Heitor Naoki Sado","orcid":"https://orcid.org/0000-0003-1913-6509","observed_orcids":["https://orcid.org/0000-0003-1913-6509"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210088998","display_name":"Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo","ror":"https://ror.org/005vqqr19","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210088998"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Heitor N. Sado","raw_affiliation_strings":["Division of Nuclear Medicine, Department of Radiology and Oncology, Medical School of University of S\u00e3o Paulo (FMUSP), S\u00e3o Paulo, Brazil","Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nuclear Medicine, Department of Radiology and Oncology, Medical School of University of S\u00e3o Paulo (FMUSP), S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]},{"raw_affiliation_string":"Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)","institution_ids":["https://openalex.org/I4210088998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087763708","display_name":"Marcelo Tatit Sapienza","orcid":"https://orcid.org/0000-0001-9766-6332","observed_orcids":["https://orcid.org/0000-0001-9766-6332"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marcelo T. Sapienza","raw_affiliation_strings":["Division of Nuclear Medicine, Department of Radiology and Oncology, Medical School of University of S\u00e3o Paulo (FMUSP), S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nuclear Medicine, Department of Radiology and Oncology, Medical School of University of S\u00e3o Paulo (FMUSP), S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056081475","display_name":"Ana O. Hoff","orcid":"https://orcid.org/0000-0002-7058-6321","observed_orcids":["https://orcid.org/0000-0002-7058-6321"]},"institutions":[{"id":"https://openalex.org/I4210088998","display_name":"Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo","ror":"https://ror.org/005vqqr19","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210088998"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ana O. Hoff","raw_affiliation_strings":["Division of Endocrinology, S\u00e3o Paulo Cancer Institute (ICESP)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, S\u00e3o Paulo Cancer Institute (ICESP)","institution_ids":["https://openalex.org/I4210088998"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055580205","display_name":"Carlos Alberto Buchpiguel","orcid":"https://orcid.org/0000-0003-0956-2790","observed_orcids":["https://orcid.org/0000-0003-0956-2790"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210088998","display_name":"Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo","ror":"https://ror.org/005vqqr19","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210088998"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carlos A. Buchpiguel","raw_affiliation_strings":["Division of Nuclear Medicine, Department of Radiology and Oncology, Medical School of University of S\u00e3o Paulo (FMUSP), S\u00e3o Paulo, Brazil","Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nuclear Medicine, Department of Radiology and Oncology, Medical School of University of S\u00e3o Paulo (FMUSP), S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]},{"raw_affiliation_string":"Division of Nuclear Medicine, S\u00e3o Paulo Cancer Institute (ICESP)","institution_ids":["https://openalex.org/I4210088998"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5074217620"],"corresponding_institution_ids":["https://openalex.org/I4210088998"],"apc_list":null,"apc_paid":null,"fwci":1.1554,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.77500059,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"41","issue":"5","first_page":"469","last_page":"476"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.00989999994635582,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medullary-thyroid-carcinoma","display_name":"medullary thyroid carcinoma","score":0.9950000047683716},{"id":"https://openalex.org/keywords/bone-metastases","display_name":"bone metastasis","score":0.781000018119812},{"id":"https://openalex.org/keywords/18f-naf-pet-ct","display_name":"18F-NaF PET/CT","score":0.9430000185966492},{"id":"https://openalex.org/keywords/metastatic-disease-burden","display_name":"metastatic disease burden","score":0.7720000147819519},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.8429999947547913},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8849999904632568},{"id":"https://openalex.org/keywords/standardized-uptake-value","display_name":"standardized uptake value","score":0.8320000171661377}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9032252430915833},{"id":"https://openalex.org/C2780120053","wikidata":"https://www.wikidata.org/wiki/Q3493538","display_name":"Medullary thyroid cancer","level":4,"score":0.8276139497756958},{"id":"https://openalex.org/C195121873","wikidata":"https://www.wikidata.org/wiki/Q1131385","display_name":"Medullary cavity","level":2,"score":0.6918569207191467},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5613340735435486},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5090024471282959},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.4455059766769409},{"id":"https://openalex.org/C2779761222","wikidata":"https://www.wikidata.org/wiki/Q826522","display_name":"Thyroid cancer","level":3,"score":0.4403392970561981},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.424931138753891},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22571715712547302},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.16340070962905884}],"mesh":[{"descriptor_ui":"D000072078","descriptor_name":"Positron Emission Tomography Computed Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005462","descriptor_name":"Fluorine Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012969","descriptor_name":"Sodium Fluoride","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018278","descriptor_name":"Carcinoma, Neuroendocrine","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D047368","descriptor_name":"Tumor Burden","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/mnm.0000000000001175","doi":"https://doi.org/10.1097/mnm.0000000000001175","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mnm.0000000000001175","pdf_url":null,"source":{"id":"https://openalex.org/S108023290","display_name":"Nuclear Medicine Communications","issn_l":"0143-3636","issn":["0143-3636","1473-5628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear Medicine Communications","raw_type":"journal-article"},{"id":"pmid:32187160","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32187160","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear medicine communications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1562435271","https://openalex.org/W1594241115","https://openalex.org/W1836600763","https://openalex.org/W1944371343","https://openalex.org/W1986002407","https://openalex.org/W1986717103","https://openalex.org/W2003388542","https://openalex.org/W2009719437","https://openalex.org/W2025700909","https://openalex.org/W2028896946","https://openalex.org/W2033814717","https://openalex.org/W2052001844","https://openalex.org/W2054341458","https://openalex.org/W2058224916","https://openalex.org/W2064347825","https://openalex.org/W2083904832","https://openalex.org/W2110101150","https://openalex.org/W2113328339","https://openalex.org/W2120659572","https://openalex.org/W2138436109","https://openalex.org/W2146044942","https://openalex.org/W2149935230","https://openalex.org/W2155382245","https://openalex.org/W2172148195","https://openalex.org/W2264243378","https://openalex.org/W2285246881","https://openalex.org/W2320663754","https://openalex.org/W2408827415","https://openalex.org/W2589822376","https://openalex.org/W2598178324","https://openalex.org/W2605021316","https://openalex.org/W2742745948","https://openalex.org/W2743122016","https://openalex.org/W2806053715","https://openalex.org/W2887229553","https://openalex.org/W2889319664","https://openalex.org/W2990324834","https://openalex.org/W3022733662","https://openalex.org/W4237214224","https://openalex.org/W6638361104","https://openalex.org/W6776828553"],"related_works":["https://openalex.org/W3090847214","https://openalex.org/W2806053715","https://openalex.org/W2598178324","https://openalex.org/W4391029130","https://openalex.org/W4394749853","https://openalex.org/W2889319664","https://openalex.org/W2237392429","https://openalex.org/W2594209010","https://openalex.org/W2964222053","https://openalex.org/W2166226643"],"abstract_inverted_index":{"PURPOSE:":[0],"The":[1,54,95,127,158],"aim":[2],"of":[3,14,30,56,83,105,171,184,208,233,252],"the":[4,9,12,26,57,66,74,81,90,112,165,168,174,181,185,188,197,200,206,231,250],"study":[5],"was":[6,87,97,177,224],"to":[7,50,119,163,179],"assess":[8,51],"association":[10],"between":[11,187,199,230],"burden":[13,82,251],"metastatic":[15,84,253],"bone":[16,85,254],"disease":[17,86,255],"measured":[18],"on":[19,65,70,103],"F-NaF":[20],"PET/computed":[21],"tomography":[22],"(CT)":[23],"studies":[24,49,75],"and":[25,121,150,173,205,216,238],"overall":[27],"survival":[28],"(OS)":[29],"patients":[31,42,58,128,172,209,234,247],"with":[32,43,142,151,202,210,235,248,258],"medullary":[33],"thyroid":[34],"cancer":[35],"(MTC).":[36],"METHODS:":[37],"We":[38],"retrospectively":[39],"analyzed":[40],"31":[41],"MTC":[44],"who":[45],"performed":[46],"18F-NaF":[47],"PET/CT":[48],"skeletal":[52,79,137,218,240],"metastases.":[53],"outcomes":[55],"(dead":[59],"or":[60],"alive)":[61],"were":[62,122,129,161,192],"established":[63,88,123],"based":[64,102],"last":[67],"information":[68],"available":[69],"their":[71],"files.":[72],"In":[73,246],"considered":[76],"positives":[77],"for":[78],"metastases,":[80],"calculating":[89],"fluoride":[91],"tumor":[92],"volume":[93],"(FTV).":[94],"FTV":[96,144,153,204,212,237],"defined":[98],"using":[99],"isocontour":[100],"thresholds":[101],"percentages":[104,115],"maximal":[106],"standardized":[107],"uptake":[108],"values":[109],"(SUVmax)":[110],"in":[111,167,196],"lesions.":[113],"These":[114],"varied":[116],"from":[117],"lesion":[118,120],"by":[124],"visual":[125],"analysis.":[126],"divided":[130],"into":[131],"three":[132,169],"groups":[133,170,207,232],"as":[134],"follows:":[135],"without":[136,217,239],"metastases":[138,219,241],"(n":[139],"=":[140,148,156,214,221,243],"11),":[141],"low":[143,211,236],"(\u226450":[145],"cm;":[146],"n":[147,155],"11)":[149],"high":[152,203],"(>50cm;":[154],"9).":[157],"Kaplan-Meier":[159],"curves":[160],"used":[162,178],"analyze":[164],"OS":[166,198],"log-rank":[175],"test":[176],"determine":[180],"statistical":[182],"significance":[183],"difference":[186,229],"groups.":[189],"RESULTS:":[190],"There":[191,223],"statistically":[193,227],"significant":[194,228],"differences":[195],"group":[201],"(P":[213,220,242],"0.036)":[215],"0.001).":[222],"not":[225],"a":[226],"0.147).":[244],"CONCLUSION:":[245],"MTC,":[249],"is":[256],"associated":[257],"OS.":[259]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-03-23T00:00:00"}