{"id":"https://openalex.org/W3010614930","doi":"https://doi.org/10.1128/mra.00073-20","title":"Genome Sequence of a Segmented Filamentous Bacterium Strain That Confers a Rotavirus Resistance Phenotype in Mice","display_name":"Genome Sequence of a Segmented Filamentous Bacterium Strain That Confers a Rotavirus Resistance Phenotype in Mice","publication_year":2020,"publication_date":"2020-03-04","ids":{"openalex":"https://openalex.org/W3010614930","doi":"https://doi.org/10.1128/mra.00073-20","mag":"3010614930","pmid":"https://pubmed.ncbi.nlm.nih.gov/32139567","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7171207"},"language":"en","primary_location":{"id":"doi:10.1128/mra.00073-20","doi":"https://doi.org/10.1128/mra.00073-20","is_oa":true,"landing_page_url":"https://doi.org/10.1128/mra.00073-20","pdf_url":null,"source":{"id":"https://openalex.org/S4210232526","display_name":"Microbiology Resource Announcements","issn_l":"2576-098X","issn":["2576-098X"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology Resource Announcements","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1128/mra.00073-20","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047454698","display_name":"Zhenda Shi","orcid":"https://orcid.org/0000-0001-8767-7230","observed_orcids":["https://orcid.org/0000-0001-8767-7230"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhenda Shi","raw_affiliation_strings":["Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025475158","display_name":"Chunyu Zhao","orcid":"https://orcid.org/0000-0003-0168-2130","observed_orcids":["https://orcid.org/0000-0003-0168-2130"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chunyu Zhao","raw_affiliation_strings":["Gastroenterology, Hepatology, and Nutrition, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology, Hepatology, and Nutrition, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044679357","display_name":"Lisa M. Mattei","orcid":"https://orcid.org/0000-0002-2238-0281","observed_orcids":["https://orcid.org/0000-0002-2238-0281"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa M. Mattei","raw_affiliation_strings":["Gastroenterology, Hepatology, and Nutrition, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology, Hepatology, and Nutrition, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066967353","display_name":"Kyle L. Bittinger","orcid":"https://orcid.org/0000-0003-3472-5934","observed_orcids":["https://orcid.org/0000-0003-3472-5934"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyle Bittinger","raw_affiliation_strings":["Gastroenterology, Hepatology, and Nutrition, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology, Hepatology, and Nutrition, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000970718","display_name":"Baoming Jiang","orcid":"https://orcid.org/0000-0003-2072-0729","observed_orcids":["https://orcid.org/0000-0003-2072-0729"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Baoming Jiang","raw_affiliation_strings":["Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019350885","display_name":"Andrew T. Gewirtz","orcid":"https://orcid.org/0000-0002-6338-7578","observed_orcids":["https://orcid.org/0000-0002-6338-7578"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrew T. Gewirtz","raw_affiliation_strings":["Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I181565077"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5019350885"],"corresponding_institution_ids":["https://openalex.org/I181565077"],"apc_list":null,"apc_paid":null,"fwci":0.1621,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.38966141,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"9","issue":"10","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.6060000061988831,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.6060000061988831,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":0.05649999901652336,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13791","display_name":"Veterinary medicine and infectious diseases","score":0.042399998754262924,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/segmented-filamentous-bacteria","display_name":"segmented filamentous bacteria","score":0.9990000128746033},{"id":"https://openalex.org/keywords/genome-sequence","display_name":"genome sequence","score":0.699999988079071},{"id":"https://openalex.org/keywords/th17-cells","display_name":"Th17 cells","score":0.8730000257492065},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.6460000276565552},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.6700000166893005},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.40299999713897705},{"id":"https://openalex.org/keywords/protective-immunity","display_name":"protective immunity","score":0.34700000286102295}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8100591897964478},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6908705830574036},{"id":"https://openalex.org/C24432333","wikidata":"https://www.wikidata.org/wiki/Q2068526","display_name":"Whole genome sequencing","level":4,"score":0.6443249583244324},{"id":"https://openalex.org/C2781367151","wikidata":"https://www.wikidata.org/wiki/Q164778","display_name":"Rotavirus","level":3,"score":0.6049752235412598},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5906625390052795},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.5549482107162476},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.5491110682487488},{"id":"https://openalex.org/C94562577","wikidata":"https://www.wikidata.org/wiki/Q2878487","display_name":"Segmented filamentous bacteria","level":4,"score":0.5470614433288574},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5014402866363525},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5005803108215332},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.47420361638069153},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.45344099402427673},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.44197359681129456},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3217908442020416},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.2901899516582489},{"id":"https://openalex.org/C2777730692","wikidata":"https://www.wikidata.org/wiki/Q815353","display_name":"Activated sludge","level":3,"score":0.0},{"id":"https://openalex.org/C548081761","wikidata":"https://www.wikidata.org/wiki/Q180388","display_name":"Waste management","level":1,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0},{"id":"https://openalex.org/C57442070","wikidata":"https://www.wikidata.org/wiki/Q221275","display_name":"Sewage treatment","level":2,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1128/mra.00073-20","doi":"https://doi.org/10.1128/mra.00073-20","is_oa":true,"landing_page_url":"https://doi.org/10.1128/mra.00073-20","pdf_url":null,"source":{"id":"https://openalex.org/S4210232526","display_name":"Microbiology Resource Announcements","issn_l":"2576-098X","issn":["2576-098X"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology Resource Announcements","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7171207","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7171207","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiol Resour Announc","raw_type":"Text"},{"id":"pmid:32139567","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32139567","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology resource announcements","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1128/mra.00073-20","doi":"https://doi.org/10.1128/mra.00073-20","is_oa":true,"landing_page_url":"https://doi.org/10.1128/mra.00073-20","pdf_url":null,"source":{"id":"https://openalex.org/S4210232526","display_name":"Microbiology Resource Announcements","issn_l":"2576-098X","issn":["2576-098X"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology Resource Announcements","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1398281606","display_name":"Molecular Basis of Reovirus Pathogenesis","funder_award_id":"R01AI038296","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G2351331872","display_name":"Molecular Basis of Reovirus Pathogenesis","funder_award_id":"R37AI038296","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G3231059705","display_name":null,"funder_award_id":"DK083890","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3483699107","display_name":null,"funder_award_id":"DK099071","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3886094530","display_name":"DECONSTRUCTING INFLAMMATION AND ALTERED MICROBIOTA IN METABOLIC SYNDROME","funder_award_id":"R01DK099071","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6168529534","display_name":"Host-Microbiota-Diet Interactions in Metabolic Syndrome and IBD","funder_award_id":"R01DK083890","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1925886892","https://openalex.org/W1970916899","https://openalex.org/W1986708244","https://openalex.org/W2096093282","https://openalex.org/W2107369528","https://openalex.org/W2112364185","https://openalex.org/W2120902911","https://openalex.org/W2519830012","https://openalex.org/W2952539125","https://openalex.org/W2979880748"],"related_works":["https://openalex.org/W2979880748","https://openalex.org/W2054539653","https://openalex.org/W2128321785","https://openalex.org/W4319293848","https://openalex.org/W2888407064","https://openalex.org/W2106711875","https://openalex.org/W2041848357","https://openalex.org/W2803417520","https://openalex.org/W3083278526","https://openalex.org/W2947267358"],"abstract_inverted_index":{"Segmented":[0],"filamentous":[1],"bacteria":[2],"(SFB)":[3],"are":[4],"well":[5],"appreciated":[6],"for":[7],"eliciting":[8],"Th17":[9],"cell":[10],"immune":[11],"responses.":[12],"Here,":[13],"we":[14],"report":[15],"the":[16],"genome":[17],"sequence":[18],"of":[19,23,33],"a":[20],"murine":[21],"isolate":[22],"SFB,":[24],"which":[25],"confers":[26],"strong":[27],"protection":[28],"against":[29],"rotavirus":[30],"infection":[31],"independent":[32],"acquired":[34],"immunity.":[35]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2020-03-13T00:00:00"}