{"id":"https://openalex.org/W3010535969","doi":null,"title":"Blood Rheology, Haemostatic Function and Peripheral Blood Flow in Diabetes Mellitus: A Study of the Effects of Improved Blood Glucose Control and Treatment With Biosynthetic Human Insulin","display_name":"Blood Rheology, Haemostatic Function and Peripheral Blood Flow in Diabetes Mellitus: A Study of the Effects of Improved Blood Glucose Control and Treatment With Biosynthetic Human Insulin","publication_year":1988,"publication_date":"1988-01-01","ids":{"openalex":"https://openalex.org/W3010535969","mag":"3010535969"},"language":"en","primary_location":{"id":"pmh:oai:theses.gla.ac.uk:77266","doi":null,"is_oa":true,"landing_page_url":"http://theses.gla.ac.uk/77266/1/10987043.pdf","pdf_url":"http://theses.gla.ac.uk/77266/1/10987043.pdf","source":{"id":"https://openalex.org/S4306401724","display_name":"Enlighten: Theses (The University of Glasgow)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I7882870","host_organization_name":"University of Glasgow","host_organization_lineage":["https://openalex.org/I7882870"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://theses.gla.ac.uk/77266/1/10987043.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103893801","display_name":"Diana Margaret Ritchie","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Diana Margaret Ritchie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5103893801"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9589999914169312},{"id":"https://openalex.org/keywords/hemorheology","display_name":"hemorheology","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hemostasis","display_name":"hemostasis","score":0.9509999752044678},{"id":"https://openalex.org/keywords/peripheral-blood-flow","display_name":"peripheral blood flow","score":0.996999979019165},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.7710000276565552},{"id":"https://openalex.org/keywords/biosynthetic-human-insulin","display_name":"biosynthetic human insulin","score":0.9179999828338623},{"id":"https://openalex.org/keywords/porcine-insulin","display_name":"porcine insulin","score":0.9879999756813049},{"id":"https://openalex.org/keywords/erythrocyte-deformability","display_name":"erythrocyte deformability","score":0.9900000095367432},{"id":"https://openalex.org/keywords/blood-viscosity","display_name":"blood viscosity","score":0.8460000157356262},{"id":"https://openalex.org/keywords/peripheral-nerve-function","display_name":"peripheral nerve function","score":0.8370000123977661},{"id":"https://openalex.org/keywords/vascular-injury","display_name":"vascular injury","score":0.753000020980835}],"concepts":[{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.667415976524353},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6567455530166626},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.6283608675003052},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6247895359992981},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.5663462281227112},{"id":"https://openalex.org/C2994203641","wikidata":"https://www.wikidata.org/wiki/Q5712543","display_name":"Blood viscosity","level":2,"score":0.5192915797233582},{"id":"https://openalex.org/C200990466","wikidata":"https://www.wikidata.org/wiki/Q271707","display_name":"Rheology","level":2,"score":0.48176121711730957},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46726980805397034},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.45938044786453247},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3672221899032593},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3244805932044983},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.12841761112213135},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12151956558227539},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:theses.gla.ac.uk:77266","doi":null,"is_oa":true,"landing_page_url":"http://theses.gla.ac.uk/77266/1/10987043.pdf","pdf_url":"http://theses.gla.ac.uk/77266/1/10987043.pdf","source":{"id":"https://openalex.org/S4306401724","display_name":"Enlighten: Theses (The University of Glasgow)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I7882870","host_organization_name":"University of Glasgow","host_organization_lineage":["https://openalex.org/I7882870"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:3010535969","doi":null,"is_oa":false,"landing_page_url":"https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.796017","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:theses.gla.ac.uk:77266","doi":null,"is_oa":true,"landing_page_url":"http://theses.gla.ac.uk/77266/1/10987043.pdf","pdf_url":"http://theses.gla.ac.uk/77266/1/10987043.pdf","source":{"id":"https://openalex.org/S4306401724","display_name":"Enlighten: Theses (The University of Glasgow)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I7882870","host_organization_name":"University of Glasgow","host_organization_lineage":["https://openalex.org/I7882870"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3010535969.pdf","grobid_xml":"https://content.openalex.org/works/W3010535969.grobid-xml"},"referenced_works_count":231,"referenced_works":["https://openalex.org/W3998058","https://openalex.org/W28263635","https://openalex.org/W51727046","https://openalex.org/W72833482","https://openalex.org/W86450761","https://openalex.org/W104837794","https://openalex.org/W124741802","https://openalex.org/W149224131","https://openalex.org/W152263196","https://openalex.org/W188370527","https://openalex.org/W206063638","https://openalex.org/W346423316","https://openalex.org/W425141852","https://openalex.org/W639934243","https://openalex.org/W1480284744","https://openalex.org/W1495106044","https://openalex.org/W1549812108","https://openalex.org/W1596126281","https://openalex.org/W1682758370","https://openalex.org/W1964184217","https://openalex.org/W1965727580","https://openalex.org/W1966780199","https://openalex.org/W1968492285","https://openalex.org/W1969533734","https://openalex.org/W1972072140","https://openalex.org/W1972909163","https://openalex.org/W1973134089","https://openalex.org/W1974821002","https://openalex.org/W1975749974","https://openalex.org/W1976806265","https://openalex.org/W1978201195","https://openalex.org/W1979352847","https://openalex.org/W1980619762","https://openalex.org/W1980952198","https://openalex.org/W1982046626","https://openalex.org/W1983825529","https://openalex.org/W1985208692","https://openalex.org/W1986971270","https://openalex.org/W1990986783","https://openalex.org/W1991355821","https://openalex.org/W1991967150","https://openalex.org/W1992946409","https://openalex.org/W1993503963","https://openalex.org/W1993928613","https://openalex.org/W1995331250","https://openalex.org/W1996234135","https://openalex.org/W1996688091","https://openalex.org/W2001049748","https://openalex.org/W2002365633","https://openalex.org/W2002910927","https://openalex.org/W2003670664","https://openalex.org/W2003774534","https://openalex.org/W2004140403","https://openalex.org/W2005042739","https://openalex.org/W2006615534","https://openalex.org/W2007919709","https://openalex.org/W2009033984","https://openalex.org/W2011259221","https://openalex.org/W2011642892","https://openalex.org/W2014179570","https://openalex.org/W2014271000","https://openalex.org/W2016703545","https://openalex.org/W2019237997","https://openalex.org/W2022096246","https://openalex.org/W2022642450","https://openalex.org/W2025732533","https://openalex.org/W2026724997","https://openalex.org/W2027331772","https://openalex.org/W2029987728","https://openalex.org/W2030392715","https://openalex.org/W2030738496","https://openalex.org/W2030934994","https://openalex.org/W2031181420","https://openalex.org/W2031327121","https://openalex.org/W2032306153","https://openalex.org/W2032371975","https://openalex.org/W2032665155","https://openalex.org/W2033424694","https://openalex.org/W2033621907","https://openalex.org/W2033665979","https://openalex.org/W2034180675","https://openalex.org/W2037311313","https://openalex.org/W2037884987","https://openalex.org/W2037994872","https://openalex.org/W2039997142","https://openalex.org/W2040396563","https://openalex.org/W2040858678","https://openalex.org/W2041799072","https://openalex.org/W2042525655","https://openalex.org/W2043065060","https://openalex.org/W2044293101","https://openalex.org/W2046035129","https://openalex.org/W2047795198","https://openalex.org/W2047920951","https://openalex.org/W2048683649","https://openalex.org/W2050727424","https://openalex.org/W2050911989","https://openalex.org/W2050966085","https://openalex.org/W2053293902","https://openalex.org/W2053863729","https://openalex.org/W2054441934","https://openalex.org/W2055776235","https://openalex.org/W2057704624","https://openalex.org/W2058812862","https://openalex.org/W2059197944","https://openalex.org/W2059387277","https://openalex.org/W2062577792","https://openalex.org/W2063252794","https://openalex.org/W2064836014","https://openalex.org/W2065299718","https://openalex.org/W2065895520","https://openalex.org/W2066673941","https://openalex.org/W2067166413","https://openalex.org/W2069509884","https://openalex.org/W2070764281","https://openalex.org/W2071354653","https://openalex.org/W2072397080","https://openalex.org/W2073936254","https://openalex.org/W2074302096","https://openalex.org/W2075504285","https://openalex.org/W2076456184","https://openalex.org/W2078967398","https://openalex.org/W2079453604","https://openalex.org/W2080733678","https://openalex.org/W2081137367","https://openalex.org/W2083012985","https://openalex.org/W2084124265","https://openalex.org/W2085438086","https://openalex.org/W2086993546","https://openalex.org/W2087592853","https://openalex.org/W2091651345","https://openalex.org/W2093223545","https://openalex.org/W2094233549","https://openalex.org/W2097575936","https://openalex.org/W2101845505","https://openalex.org/W2109513694","https://openalex.org/W2113850105","https://openalex.org/W2115685425","https://openalex.org/W2115947225","https://openalex.org/W2116484301","https://openalex.org/W2116529608","https://openalex.org/W2120992318","https://openalex.org/W2122610136","https://openalex.org/W2125781124","https://openalex.org/W2128664810","https://openalex.org/W2135189810","https://openalex.org/W2136411192","https://openalex.org/W2137398448","https://openalex.org/W2145294053","https://openalex.org/W2146390460","https://openalex.org/W2148101123","https://openalex.org/W2156010457","https://openalex.org/W2157440753","https://openalex.org/W2159162837","https://openalex.org/W2162951947","https://openalex.org/W2169495914","https://openalex.org/W2197701764","https://openalex.org/W2265221389","https://openalex.org/W2277215750","https://openalex.org/W2313945403","https://openalex.org/W2315056881","https://openalex.org/W2328168121","https://openalex.org/W2329314370","https://openalex.org/W2331879659","https://openalex.org/W2334530236","https://openalex.org/W2340615200","https://openalex.org/W2394858131","https://openalex.org/W2396772007","https://openalex.org/W2397374393","https://openalex.org/W2398610979","https://openalex.org/W2399250667","https://openalex.org/W2399784954","https://openalex.org/W2400064903","https://openalex.org/W2400510049","https://openalex.org/W2400765833","https://openalex.org/W2401018342","https://openalex.org/W2402589872","https://openalex.org/W2405153624","https://openalex.org/W2405721703","https://openalex.org/W2406292998","https://openalex.org/W2406811761","https://openalex.org/W2407601226","https://openalex.org/W2407866941","https://openalex.org/W2409156667","https://openalex.org/W2409172460","https://openalex.org/W2409333088","https://openalex.org/W2409519390","https://openalex.org/W2409816945","https://openalex.org/W2410008074","https://openalex.org/W2412145055","https://openalex.org/W2412309576","https://openalex.org/W2412427777","https://openalex.org/W2413305411","https://openalex.org/W2413481648","https://openalex.org/W2413558182","https://openalex.org/W2413561198","https://openalex.org/W2413572454","https://openalex.org/W2415660624","https://openalex.org/W2417382969","https://openalex.org/W2417406145","https://openalex.org/W2417667784","https://openalex.org/W2417781284","https://openalex.org/W2418070784","https://openalex.org/W2418999676","https://openalex.org/W2419332048","https://openalex.org/W2424590401","https://openalex.org/W2428351909","https://openalex.org/W2433332121","https://openalex.org/W2443438246","https://openalex.org/W2461110131","https://openalex.org/W2461720415","https://openalex.org/W2463312362","https://openalex.org/W2464457621","https://openalex.org/W2465588704","https://openalex.org/W2469289495","https://openalex.org/W2474215978","https://openalex.org/W2475253248","https://openalex.org/W2475356407","https://openalex.org/W2502987629","https://openalex.org/W2512181416","https://openalex.org/W2528381731","https://openalex.org/W2563638504","https://openalex.org/W2565415657","https://openalex.org/W2611127318","https://openalex.org/W2623302278","https://openalex.org/W2913618975","https://openalex.org/W2993125267","https://openalex.org/W3209207000","https://openalex.org/W4231265939","https://openalex.org/W4317523400","https://openalex.org/W4320801088"],"related_works":["https://openalex.org/W2409816945","https://openalex.org/W2410530253","https://openalex.org/W2045177557","https://openalex.org/W1546446573","https://openalex.org/W7006379790","https://openalex.org/W2030738496","https://openalex.org/W2525450337","https://openalex.org/W1633337746","https://openalex.org/W2417426100","https://openalex.org/W2034180675"],"abstract_inverted_index":{"The":[0],"aims":[1],"of":[2,26,31,34,38,45,53,82,85],"the":[3,24,32,51,83],"studies":[4,30],"were":[5,48],"to":[6,21],"examine":[7],"blood":[8,14,55,64,69,98,104],"rheology,":[9,99],"haemostatic":[10,66,100],"factors":[11,101],"and":[12,23,71,92,102],"peripheral":[13,68,72,103],"flow":[15,70,105],"in":[16,19],"diabetes":[17],"mellitus":[18],"relation":[20],"treatment":[22,86],"presence":[25],"vascular":[27],"damage.":[28],"First,":[29],"specificity":[33],"positive":[35],"pressure":[36],"filtration":[37],"dilute":[39],"erythrocyte":[40,46],"suspensions":[41],"as":[42],"a":[43,78],"measure":[44],"deformability":[47],"made.":[49],"Second,":[50],"effects":[52,84],"improved":[54],"glucose":[56],"control":[57],"(achieved":[58],"by":[59],"outpatient":[60],"management)":[61],"on":[62,97],"whole":[63],"viscosity,":[65],"factors,":[67],"nerve":[73],"function":[74],"was":[75,106],"examined.":[76],"Third,":[77],"double-blind":[79],"crossover":[80],"study":[81],"with":[87],"biosynthetic":[88],"human":[89],"insulin":[90,95],"(BHI)":[91],"purified":[93],"porcine":[94],"(PPI)":[96],"carried":[107],"out.":[108]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-03-13T00:00:00"}