{"id":"https://openalex.org/W3009603486","doi":"https://doi.org/10.1158/1538-7445.sabcs19-p2-08-19","title":"Abstract P2-08-19: Disparities in triple negative breast cancer survival in the United States by patient characteristics: A population-based study from SEER database, 2010 - 2015","display_name":"Abstract P2-08-19: Disparities in triple negative breast cancer survival in the United States by patient characteristics: A population-based study from SEER database, 2010 - 2015","publication_year":2020,"publication_date":"2020-02-15","ids":{"openalex":"https://openalex.org/W3009603486","doi":"https://doi.org/10.1158/1538-7445.sabcs19-p2-08-19","mag":"3009603486"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7445.sabcs19-p2-08-19","doi":"https://doi.org/10.1158/1538-7445.sabcs19-p2-08-19","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.sabcs19-p2-08-19","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Zikun Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zikun Wang","raw_affiliation_strings":["1Department of Epidemiology and Biostatistics, Indiana University Bloomington, Bloomington, IN;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Epidemiology and Biostatistics, Indiana University Bloomington, Bloomington, IN;","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108629844","display_name":"Zheyu Lu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283055418","display_name":"Indiana University Health","ror":"https://ror.org/01aaptx40","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283055418","https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I2799974947","display_name":"Ball Memorial Hospital","ror":"https://ror.org/04d54np47","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283055418","https://openalex.org/I2799974947","https://openalex.org/I4388446366","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zheyu Lu","raw_affiliation_strings":["2Department of Internal Medicine, Ball Memorial Hospital, Indiana University Health, Muncie, IN;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Department of Internal Medicine, Ball Memorial Hospital, Indiana University Health, Muncie, IN;","institution_ids":["https://openalex.org/I1283055418","https://openalex.org/I2799974947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032493706","display_name":"Maitri Kalra","orcid":"https://orcid.org/0000-0002-6635-6152","observed_orcids":["https://orcid.org/0000-0002-6635-6152"]},"institutions":[{"id":"https://openalex.org/I2799974947","display_name":"Ball Memorial Hospital","ror":"https://ror.org/04d54np47","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283055418","https://openalex.org/I2799974947","https://openalex.org/I4388446366","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maitri Kalra","raw_affiliation_strings":["3Indiana University Health Ball Memorial Cancer Center, Muncie, IN;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Indiana University Health Ball Memorial Cancer Center, Muncie, IN;","institution_ids":["https://openalex.org/I2799974947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060889456","display_name":"Zhongxue Chen","orcid":"https://orcid.org/0000-0003-2537-7843","observed_orcids":["https://orcid.org/0000-0003-2537-7843"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhongxue Chen","raw_affiliation_strings":["1Department of Epidemiology and Biostatistics, Indiana University Bloomington, Bloomington, IN;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Epidemiology and Biostatistics, Indiana University Bloomington, Bloomington, IN;","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009233859","display_name":"Yi Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yi Dong","raw_affiliation_strings":["4Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, IN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, IN","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"80","issue":"4_Supplement","first_page":"P2","last_page":"08"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/triple-negative-breast-cancer","display_name":"triple-negative breast cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/breast-cancer-survival","display_name":"breast cancer survival","score":0.7860000133514404},{"id":"https://openalex.org/keywords/age-disparities","display_name":"age disparities","score":0.6420000195503235},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.6890000104904175},{"id":"https://openalex.org/keywords/racial-disparities","display_name":"racial disparities","score":0.6869999766349792},{"id":"https://openalex.org/keywords/marital-status","display_name":"marital status","score":0.777999997138977},{"id":"https://openalex.org/keywords/breast-cancer-screening","display_name":"breast cancer screening","score":0.5920000076293945},{"id":"https://openalex.org/keywords/metastatic-disease","display_name":"metastatic disease","score":0.753000020980835},{"id":"https://openalex.org/keywords/lymph-node-involvement","display_name":"lymph node involvement","score":0.8799999952316284},{"id":"https://openalex.org/keywords/treatment-disparities","display_name":"treatment disparities","score":0.36800000071525574},{"id":"https://openalex.org/keywords/breast-cancer-specific-survival","display_name":"breast cancer-specific survival","score":0.593999981880188},{"id":"https://openalex.org/keywords/seer-database","display_name":"SEER database","score":0.722000002861023}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8761233687400818},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.7609297037124634},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6952040791511536},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6617307662963867},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.5535757541656494},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.553385317325592},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5028931498527527},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.48660576343536377},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4664765000343323},{"id":"https://openalex.org/C2779391198","wikidata":"https://www.wikidata.org/wiki/Q7647035","display_name":"Surveillance, Epidemiology, and End Results","level":4,"score":0.45466887950897217},{"id":"https://openalex.org/C2780110267","wikidata":"https://www.wikidata.org/wiki/Q7843332","display_name":"Triple-negative breast cancer","level":4,"score":0.44815030694007874},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.42895227670669556},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.42447373270988464},{"id":"https://openalex.org/C2781354955","wikidata":"https://www.wikidata.org/wiki/Q11920938","display_name":"Marital status","level":3,"score":0.4213995039463043},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4166056513786316},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.4039367437362671},{"id":"https://openalex.org/C2778527826","wikidata":"https://www.wikidata.org/wiki/Q1787017","display_name":"Cancer registry","level":3,"score":0.3518563508987427},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.33583736419677734},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.05831718444824219},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7445.sabcs19-p2-08-19","doi":"https://doi.org/10.1158/1538-7445.sabcs19-p2-08-19","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.sabcs19-p2-08-19","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.7578999996185303,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1434774485","https://openalex.org/W2790544699","https://openalex.org/W609467180","https://openalex.org/W7098050410","https://openalex.org/W2758507685","https://openalex.org/W2660679094","https://openalex.org/W2612233476","https://openalex.org/W2790621810","https://openalex.org/W4366396984","https://openalex.org/W2563553756"],"abstract_inverted_index":{"Abstract":[0],"Introduction:":[1],"Efforts":[2],"to":[3,19,61,81,101,119,188,212,380,412,423,485],"improve":[4],"the":[5,17,21,66,86,132,205,228,237,321,370,451,493,550,574,593],"outcomes":[6],"of":[7,55,72,208,241,255,273,295,326,340,345,353,373,384,393,427,444,524,530,592],"triple":[8,568],"negative":[9,569],"breast":[10,125,190,570],"cancer":[11,126,191,571],"(TNBC)":[12],"have":[13,189,358,369,381,390,424],"been":[14],"hampered":[15],"by":[16,37,65,182,577],"inability":[18],"identify":[20],"key":[22],"risk":[23],"factors":[24,517],"for":[25,131,198,450,479,543],"prognosis.":[26,536],"We":[27,168],"focus":[28],"solely":[29],"on":[30],"female":[31,74,388],"TNBC":[32,63,78,535],"and":[33,42,48,107,139,145,160,194,261,278,289,300,312,407,466,515,518,527,545],"explored":[34],"its":[35],"survival":[36,64,128,458,494,572],"age,":[38],"marital":[39],"status,":[40],"treatment":[41],"race.":[43],"Data":[44],"from":[45,79,222,583],"Surveillance,":[46],"Epidemiology":[47],"End":[49],"Results":[50],"Program":[51],"(SEER)":[52],"Database":[53],"18":[54],"National":[56],"Cancer":[57,598,609],"Institute":[58],"were":[59,83],"used":[60],"assess":[62],"above":[67,551],"factors.":[68],"Results:":[69],"A":[70,580],"total":[71],"26,413":[73],"patients":[75,249,302,347,368,389,456,473,497],"diagnosed":[76],"with":[77,114,117,335,419,439,507],"2010":[80,586],"2015":[82,588],"included":[84],"in":[85,157,163,333,405,472,495,504,549,567,573],"current":[87],"study,":[88],"including":[89],"15840":[90],"(60.0%)":[91],"Non-Hispanic":[92],"white":[93],"women.":[94],"The":[95,124,292,317,342,501],"follow":[96],"up":[97],"time":[98],"ranges:":[99],"0":[100],"83":[102],"months.":[103],"Younger":[104],"(\u2264":[105,136],"49)":[106],"elderly":[108,171,496],"(\u2265":[109],"65)":[110,141],"age":[111,121,134,234,286,294,436,510],"is":[112,252,282,348,437,470],"associated":[113,438],"poorer":[115],"survival,":[116],"reference":[118],"middle":[120,233],"group":[122,172,180,223,414,417],"(50-64).":[123],"specific":[127],"(BCSS)":[129],"rate":[130,207,240,325,339,344],"three":[133],"groups":[135],"49,":[137],"50-64":[138],"\u2265":[140,164,454,499],"are":[142,378,477],"78.6%,":[143],"81.0%":[144],"78.1%,":[146],"respectively;":[147],"hazard":[148],"ratio":[149],"(HR)":[150],"(95%":[151,215,244,329],"confidence":[152],"interval":[153],"[CI]):":[154],"1.17":[155],"(1.08-1.27)":[156],"\u2264":[158],"49":[159],"1.24":[161],"(1.15-1.34)":[162],"65":[165,177],"patients,":[166],"individually.":[167],"further":[169],"categorized":[170],"into":[173],"two":[174,552],"strata:":[175],"aged":[176,224,474,498],"-74":[178],"(age":[179],"recommended":[181,197,478],"U.S.":[183],"Preventive":[184],"Services":[185],"Task":[186],"Force":[187],"[BC]":[192],"screening)":[193],"\u226575":[195,229],"(not":[196],"BC":[199,445,480,547],"screening).":[200],"Our":[201,362,537],"data":[202],"revealed":[203],"that":[204,352,366,377,453,469,512],"BCSS":[206,239,324,343],"65-74":[209],"cohort":[210,319],"rises":[211],"81.9%;":[213],"HR":[214,243],"CI):":[216,245,330],"0.97":[217],"(0.88-1.07),":[218],"not":[219],"significantly":[220,359],"different":[221],"50-64.":[225],"In":[226,248],"contrast,":[227],"group,":[230,421],"as":[231],"against":[232],"cohort,":[235],"has":[236,320],"worst":[238,323,467],"71.6%;":[242],"1.74":[246],"(1.58-1.92).":[247],"\u226575,":[250],"there":[251],"highest":[253,371,401,461],"proportion":[254,392,523,529],"metastatic":[256,408,462],"disease":[257,409,463],"(2.9%)":[258],"at":[259,303,464],"diagnosis":[260,304,465],"advanced":[262,360],"lymph":[263],"node":[264],"involvement":[265],"(N2":[266],"+":[267,397],"N3":[268],"=":[269,399],"11.9%);":[270],"their":[271,519],"percentage":[272,372,426],"receiving":[274,531],"perioperative":[275],"chemotherapy":[276],"(CT)":[277],"radiation":[279],"therapy":[280,490],"(RT)":[281],"lowest":[283],"across":[284],"all":[285,403],"groups:":[287],"33.3%":[288],"43.6%,":[290],"respectively.":[291,316,433],"mean":[293],"single":[296,318,346,367,387,505],"(never":[297],"married),":[298],"married":[299,336,420],"widowed":[301,354,413],"was":[305],"52":[306],"\u00b1":[307,310,314],"13,":[308],"56":[309],"12":[311],"72":[313],"11,":[315],"second":[322],"76.1%":[327],"[HR":[328],"1.46":[331],"(1.34-1.59)],":[332],"comparison":[334],"women":[337,375,404,506,526],"(BCSS":[338],"81.6%).":[341],"only":[349],"better":[350],"than":[351],"population":[355],"(74.7%),":[356],"who":[357,476],"age.":[361],"analyses":[363],"also":[364],"showed":[365],"Black":[374],"(37.7%)":[376],"known":[379],"unfavorable":[382],"prognosis":[383],"TNBC.":[385],"Also,":[386],"high":[391,522],"large":[394],"tumor":[395],"(T3":[396],"T4":[398],"18.5%,":[400],"among":[402],"study)":[406],"(2.9%,":[410],"secondary":[411],"only).":[415],"Single":[416],"compared":[418],"tends":[422],"lower":[425],"completing":[428],"RT:":[429],"49.9%":[430],"versus":[431],"53.4%,":[432],"Conclusion:":[434],"Advanced":[435],"worse":[440],"BCSS.":[441],"However,":[442],"discontinuation":[443],"screening":[446,548],"may":[447,491,533],"partly":[448],"account":[449],"phenomenon":[452],"75-year-old":[455],"lost":[457],"benefits":[459],"(i.e.,":[460],"BCSS),":[468],"maintained":[471],"65-74,":[475],"screening.":[481],"Further,":[482],"low":[483,528],"adherence":[484],"receive":[486],"or":[487],"complete":[488],"adjuvant":[489],"attenuate":[492],"75.":[500],"poor":[502],"outcome":[503],"relatively":[508],"young":[509],"indicates":[511],"both":[513],"biological":[514],"socioeconomic":[516],"interactions":[520],"(e.g.,":[521],"black":[525],"RT)":[532],"influence":[534],"findings":[538],"suggest":[539],"a":[540],"greater":[541],"need":[542],"early":[544],"extended":[546],"populations.":[553],"Citation":[554],"Format:":[555],"Zikun":[556],"Wang,":[557],"Zheyu":[558],"Lu,":[559],"Maitri":[560],"Kalra,":[561],"Zhongxue":[562],"Chen,":[563],"Yi":[564],"Dong.":[565],"Disparities":[566],"United":[575],"States":[576],"patient":[578],"characteristics:":[579],"population-based":[581],"study":[582],"SEER":[584],"database,":[585],"-":[587],"[abstract].":[589],"In:":[590],"Proceedings":[591],"2019":[594,600],"San":[595,603],"Antonio":[596],"Breast":[597],"Symposium;":[599],"Dec":[601],"10-14;":[602],"Antonio,":[604],"TX.":[605],"Philadelphia":[606],"(PA):":[607],"AACR;":[608],"Res":[610],"2020;80(4":[611],"Suppl):Abstract":[612],"nr":[613],"P2-08-19.":[614]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2020-03-13T00:00:00"}