{"id":"https://openalex.org/W3007906283","doi":null,"title":"Cystic fibrosis in the era of effective treatment: Informing targeted therapy and influencing reproductive decision-making","display_name":"Cystic fibrosis in the era of effective treatment: Informing targeted therapy and influencing reproductive decision-making","publication_year":2019,"publication_date":"2019-05-03","ids":{"openalex":"https://openalex.org/W3007906283","mag":"3007906283"},"language":"en","primary_location":{"id":"mag:3007906283","doi":null,"is_oa":false,"landing_page_url":"https://jscholarship.library.jhu.edu/handle/1774.2/61939","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061581970","display_name":"Allison F. McCague","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Allison F. McCague","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5061581970"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11412","display_name":"Genetic and Kidney Cyst Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":1.0},{"id":"https://openalex.org/keywords/targeted-therapy","display_name":"targeted therapy","score":0.8479999899864197},{"id":"https://openalex.org/keywords/reproductive-decision-making","display_name":"reproductive decision-making","score":0.9829999804496765},{"id":"https://openalex.org/keywords/fertility-preservation","display_name":"fertility preservation","score":0.5720000267028809},{"id":"https://openalex.org/keywords/cftr-modulators","display_name":"CFTR modulators","score":0.6790000200271606}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5373856425285339},{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.4780424237251282},{"id":"https://openalex.org/C2781230642","wikidata":"https://www.wikidata.org/wiki/Q492646","display_name":"Targeted therapy","level":3,"score":0.4690103232860565},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.36361071467399597},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.34048134088516235},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28942760825157166},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0686749815940857}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3007906283","doi":null,"is_oa":false,"landing_page_url":"https://jscholarship.library.jhu.edu/handle/1774.2/61939","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":173,"referenced_works":["https://openalex.org/W135473706","https://openalex.org/W294767772","https://openalex.org/W1511128892","https://openalex.org/W1549773614","https://openalex.org/W1553487990","https://openalex.org/W1589654967","https://openalex.org/W1739452457","https://openalex.org/W1745204207","https://openalex.org/W1837900954","https://openalex.org/W1892737480","https://openalex.org/W1954895018","https://openalex.org/W1969697265","https://openalex.org/W1970723876","https://openalex.org/W1971034551","https://openalex.org/W1973229785","https://openalex.org/W1973268693","https://openalex.org/W1976185198","https://openalex.org/W1976197028","https://openalex.org/W1978991565","https://openalex.org/W1979094470","https://openalex.org/W1982884117","https://openalex.org/W1985927968","https://openalex.org/W1987519006","https://openalex.org/W1988244671","https://openalex.org/W1990213877","https://openalex.org/W1990594741","https://openalex.org/W1990725675","https://openalex.org/W1990991203","https://openalex.org/W1991506216","https://openalex.org/W1991980138","https://openalex.org/W1992555658","https://openalex.org/W1992832805","https://openalex.org/W1997863242","https://openalex.org/W2000313457","https://openalex.org/W2002352467","https://openalex.org/W2007370941","https://openalex.org/W2013518966","https://openalex.org/W2017748914","https://openalex.org/W2018862827","https://openalex.org/W2019600020","https://openalex.org/W2020117714","https://openalex.org/W2021044954","https://openalex.org/W2021494469","https://openalex.org/W2023305685","https://openalex.org/W2023442895","https://openalex.org/W2024459122","https://openalex.org/W2025970060","https://openalex.org/W2026502021","https://openalex.org/W2035131077","https://openalex.org/W2035591500","https://openalex.org/W2039599894","https://openalex.org/W2043569281","https://openalex.org/W2046084748","https://openalex.org/W2046445674","https://openalex.org/W2049094551","https://openalex.org/W2050275584","https://openalex.org/W2051135087","https://openalex.org/W2052461624","https://openalex.org/W2052522489","https://openalex.org/W2052588826","https://openalex.org/W2053471558","https://openalex.org/W2056297572","https://openalex.org/W2061405626","https://openalex.org/W2063571408","https://openalex.org/W2063982725","https://openalex.org/W2071407356","https://openalex.org/W2072497619","https://openalex.org/W2073361398","https://openalex.org/W2076138292","https://openalex.org/W2079249675","https://openalex.org/W2080130466","https://openalex.org/W2080922418","https://openalex.org/W2081376201","https://openalex.org/W2085011757","https://openalex.org/W2086293424","https://openalex.org/W2088504846","https://openalex.org/W2088679601","https://openalex.org/W2089924033","https://openalex.org/W2092373383","https://openalex.org/W2099431847","https://openalex.org/W2102102632","https://openalex.org/W2103879666","https://openalex.org/W2104305629","https://openalex.org/W2104879591","https://openalex.org/W2104901835","https://openalex.org/W2107889478","https://openalex.org/W2108678383","https://openalex.org/W2111533289","https://openalex.org/W2114927711","https://openalex.org/W2114999674","https://openalex.org/W2115046089","https://openalex.org/W2115127888","https://openalex.org/W2116326069","https://openalex.org/W2118737448","https://openalex.org/W2120787358","https://openalex.org/W2121996960","https://openalex.org/W2122484880","https://openalex.org/W2125391335","https://openalex.org/W2127237723","https://openalex.org/W2127589942","https://openalex.org/W2128557584","https://openalex.org/W2132518054","https://openalex.org/W2132821877","https://openalex.org/W2138127281","https://openalex.org/W2138742383","https://openalex.org/W2139788027","https://openalex.org/W2140407450","https://openalex.org/W2140868856","https://openalex.org/W2141429353","https://openalex.org/W2143698296","https://openalex.org/W2150873443","https://openalex.org/W2152693543","https://openalex.org/W2153054139","https://openalex.org/W2153075441","https://openalex.org/W2153306196","https://openalex.org/W2161608830","https://openalex.org/W2162033607","https://openalex.org/W2162927053","https://openalex.org/W2165700891","https://openalex.org/W2167093496","https://openalex.org/W2170832171","https://openalex.org/W2172086931","https://openalex.org/W2242995343","https://openalex.org/W2251578611","https://openalex.org/W2269069682","https://openalex.org/W2321608101","https://openalex.org/W2327599549","https://openalex.org/W2327703579","https://openalex.org/W2330134049","https://openalex.org/W2335810313","https://openalex.org/W2337925307","https://openalex.org/W2341793937","https://openalex.org/W2405094818","https://openalex.org/W2411346046","https://openalex.org/W2413729560","https://openalex.org/W2441143209","https://openalex.org/W2470629757","https://openalex.org/W2473069065","https://openalex.org/W2519999929","https://openalex.org/W2538627448","https://openalex.org/W2546156442","https://openalex.org/W2552324014","https://openalex.org/W2559862927","https://openalex.org/W2560277803","https://openalex.org/W2560770257","https://openalex.org/W2564673452","https://openalex.org/W2565418011","https://openalex.org/W2587479628","https://openalex.org/W2593956993","https://openalex.org/W2614452305","https://openalex.org/W2620997182","https://openalex.org/W2624387478","https://openalex.org/W2766037006","https://openalex.org/W2768922916","https://openalex.org/W2788613641","https://openalex.org/W2790775622","https://openalex.org/W2803899956","https://openalex.org/W2810164060","https://openalex.org/W2810212213","https://openalex.org/W2884228015","https://openalex.org/W2885499809","https://openalex.org/W2887886950","https://openalex.org/W2887996376","https://openalex.org/W2890894432","https://openalex.org/W2890998576","https://openalex.org/W2897626245","https://openalex.org/W2900002620","https://openalex.org/W2901667205","https://openalex.org/W2903680557","https://openalex.org/W2917538474","https://openalex.org/W3106798016","https://openalex.org/W4243260584","https://openalex.org/W4249315256"],"related_works":["https://openalex.org/W4231479532","https://openalex.org/W2952016250","https://openalex.org/W4367599432","https://openalex.org/W2403731981","https://openalex.org/W2461064708","https://openalex.org/W2882057309","https://openalex.org/W2950970729","https://openalex.org/W2406761527","https://openalex.org/W4386964035","https://openalex.org/W2413288650"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-03-06T00:00:00"}