{"id":"https://openalex.org/W3007262147","doi":"https://doi.org/10.1167/tvst.9.3.22","title":"QuPath Automated Analysis of Optic Nerve Degeneration in Brown Norway Rats","display_name":"QuPath Automated Analysis of Optic Nerve Degeneration in Brown Norway Rats","publication_year":2020,"publication_date":"2020-02-18","ids":{"openalex":"https://openalex.org/W3007262147","doi":"https://doi.org/10.1167/tvst.9.3.22","mag":"3007262147","pmid":"https://pubmed.ncbi.nlm.nih.gov/32714648","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7353320"},"language":"en","primary_location":{"id":"doi:10.1167/tvst.9.3.22","doi":"https://doi.org/10.1167/tvst.9.3.22","is_oa":true,"landing_page_url":"https://doi.org/10.1167/tvst.9.3.22","pdf_url":null,"source":{"id":"https://openalex.org/S2764591444","display_name":"Translational Vision Science & Technology","issn_l":"2164-2591","issn":["2164-2591"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315919","host_organization_name":"Association for Research in Vision and Ophthalmology","host_organization_lineage":["https://openalex.org/P4310315919"],"host_organization_lineage_names":["Association for Research in Vision and Ophthalmology"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational Vision Science &amp; Technology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1167/tvst.9.3.22","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006524742","display_name":"Barbara A. Mysona","orcid":"https://orcid.org/0000-0002-7632-5755","observed_orcids":["https://orcid.org/0000-0002-7632-5755"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barbara A. Mysona","raw_affiliation_strings":["Department of Cellular Biology and Anatomy, Medical College of Georgia at Augusta University, Augusta, GA, USA","James and Jean Culver Vision Discovery Institute, Medical College of Georgia at Augusta University, Augusta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology and Anatomy, Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]},{"raw_affiliation_string":"James and Jean Culver Vision Discovery Institute, Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090689427","display_name":"Sharmila Segar","orcid":"https://orcid.org/0000-0002-7947-3251","observed_orcids":["https://orcid.org/0000-0002-7947-3251"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharmila Segar","raw_affiliation_strings":["Medical College of Georgia at Augusta University, Augusta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035207654","display_name":"Cecilia Hernandez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cecilia Hernandez","raw_affiliation_strings":["Medical College of Georgia at Augusta University, Augusta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021726484","display_name":"Christian U. Kim","orcid":"https://orcid.org/0000-0003-1591-1571","observed_orcids":["https://orcid.org/0000-0003-1591-1571"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christian Kim","raw_affiliation_strings":["Medical College of Georgia at Augusta University, Augusta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110596877","display_name":"Jing Zhao","orcid":"https://orcid.org/0000-0001-5884-0473","observed_orcids":["https://orcid.org/0000-0001-5884-0473"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jing Zhao","raw_affiliation_strings":["Department of Ophthalmology, Medical College of Georgia at Augusta University, Augusta, GA, USA","James and Jean Culver Vision Discovery Institute, Medical College of Georgia at Augusta University, Augusta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]},{"raw_affiliation_string":"James and Jean Culver Vision Discovery Institute, Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091376515","display_name":"David Mysona","orcid":"https://orcid.org/0000-0003-4203-1123","observed_orcids":["https://orcid.org/0000-0003-4203-1123"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Mysona","raw_affiliation_strings":["Medical College of Georgia at Augusta University, Augusta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062323743","display_name":"Kathryn E. Bollinger","orcid":"https://orcid.org/0000-0002-2289-4899","observed_orcids":["https://orcid.org/0000-0002-2289-4899"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kathryn E. Bollinger","raw_affiliation_strings":["Department of Ophthalmology, Medical College of Georgia at Augusta University, Augusta, GA, USA","James and Jean Culver Vision Discovery Institute, Medical College of Georgia at Augusta University, Augusta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]},{"raw_affiliation_string":"James and Jean Culver Vision Discovery Institute, Medical College of Georgia at Augusta University, Augusta, GA, USA","institution_ids":["https://openalex.org/I25041050"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062323743"],"corresponding_institution_ids":["https://openalex.org/I25041050"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":1.7582,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.83022486,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"9","issue":"3","first_page":"22","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.5098000168800354,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.5098000168800354,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.3366999924182892,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.07599999755620956,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/qupath","display_name":"QuPath","score":0.8059999942779541},{"id":"https://openalex.org/keywords/optic-nerve-degeneration","display_name":"optic nerve degeneration","score":0.9829999804496765},{"id":"https://openalex.org/keywords/axonal-loss","display_name":"axonal loss","score":0.8149999976158142},{"id":"https://openalex.org/keywords/axonal-morphology","display_name":"axon morphology","score":0.7160000205039978},{"id":"https://openalex.org/keywords/gliosis","display_name":"gliosis","score":0.8339999914169312},{"id":"https://openalex.org/keywords/brown-norway-rats","display_name":"Brown Norway rats","score":0.8149999976158142},{"id":"https://openalex.org/keywords/automated-image-analysis","display_name":"automated image analysis","score":0.7670000195503235},{"id":"https://openalex.org/keywords/glaucoma-model","display_name":"glaucoma model","score":0.6650000214576721},{"id":"https://openalex.org/keywords/axon-diameter","display_name":"axon diameter","score":0.609000027179718},{"id":"https://openalex.org/keywords/toluidine-blue-staining","display_name":"toluidine blue staining","score":0.9150000214576721}],"concepts":[{"id":"https://openalex.org/C2779530196","wikidata":"https://www.wikidata.org/wiki/Q178999","display_name":"Axon","level":2,"score":0.9368054866790771},{"id":"https://openalex.org/C2780837183","wikidata":"https://www.wikidata.org/wiki/Q186029","display_name":"Optic nerve","level":2,"score":0.6045379638671875},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.480839341878891},{"id":"https://openalex.org/C93877712","wikidata":"https://www.wikidata.org/wiki/Q132560","display_name":"Electron microscope","level":2,"score":0.43960684537887573},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40885865688323975},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.4003097414970398},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3506011664867401},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.33346402645111084},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28336775302886963},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1672142744064331},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.09624642133712769}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009410","descriptor_name":"Nerve Degeneration","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009900","descriptor_name":"Optic Nerve","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D011914","descriptor_name":"Rats, Inbred BN","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020221","descriptor_name":"Optic Nerve Injuries","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1167/tvst.9.3.22","doi":"https://doi.org/10.1167/tvst.9.3.22","is_oa":true,"landing_page_url":"https://doi.org/10.1167/tvst.9.3.22","pdf_url":null,"source":{"id":"https://openalex.org/S2764591444","display_name":"Translational Vision Science & Technology","issn_l":"2164-2591","issn":["2164-2591"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315919","host_organization_name":"Association for Research in Vision and Ophthalmology","host_organization_lineage":["https://openalex.org/P4310315919"],"host_organization_lineage_names":["Association for Research in Vision and Ophthalmology"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational Vision Science &amp; Technology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7353320","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7353320","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transl Vis Sci Technol","raw_type":"Text"},{"id":"pmid:32714648","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32714648","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational vision science & technology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1167/tvst.9.3.22","doi":"https://doi.org/10.1167/tvst.9.3.22","is_oa":true,"landing_page_url":"https://doi.org/10.1167/tvst.9.3.22","pdf_url":null,"source":{"id":"https://openalex.org/S2764591444","display_name":"Translational Vision Science & Technology","issn_l":"2164-2591","issn":["2164-2591"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315919","host_organization_name":"Association for Research in Vision and Ophthalmology","host_organization_lineage":["https://openalex.org/P4310315919"],"host_organization_lineage_names":["Association for Research in Vision and Ophthalmology"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational Vision Science &amp; Technology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3152988427","display_name":"Center Core Grant for Vision Research","funder_award_id":"P30EY031631","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G9000892976","display_name":"The Mechanism of Sigma 1 Receptor Mediated Neuroprotection in Glaucoma","funder_award_id":"R01EY027406","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W6335717","https://openalex.org/W101415828","https://openalex.org/W114788794","https://openalex.org/W1469436817","https://openalex.org/W1479957045","https://openalex.org/W1500098984","https://openalex.org/W1553218248","https://openalex.org/W1596681812","https://openalex.org/W1601103168","https://openalex.org/W1682771268","https://openalex.org/W1843851062","https://openalex.org/W1938186605","https://openalex.org/W1968143827","https://openalex.org/W1973090648","https://openalex.org/W1979930462","https://openalex.org/W1984149670","https://openalex.org/W1991677561","https://openalex.org/W1993136367","https://openalex.org/W1994893435","https://openalex.org/W1996643211","https://openalex.org/W1996807228","https://openalex.org/W2001089523","https://openalex.org/W2027185272","https://openalex.org/W2034742711","https://openalex.org/W2046616637","https://openalex.org/W2058203625","https://openalex.org/W2072465036","https://openalex.org/W2076502778","https://openalex.org/W2094520489","https://openalex.org/W2099540110","https://openalex.org/W2130105499","https://openalex.org/W2143472502","https://openalex.org/W2163925135","https://openalex.org/W2167279371","https://openalex.org/W2193723006","https://openalex.org/W2252793112","https://openalex.org/W2405405482","https://openalex.org/W2617737588","https://openalex.org/W2761604622","https://openalex.org/W2952481429","https://openalex.org/W4230648938","https://openalex.org/W4236184533","https://openalex.org/W4251380844","https://openalex.org/W4252141945","https://openalex.org/W4290252244"],"related_works":["https://openalex.org/W4324129702","https://openalex.org/W2001089523","https://openalex.org/W2405405482","https://openalex.org/W4324129795","https://openalex.org/W1979930462","https://openalex.org/W4225736910","https://openalex.org/W7095177959","https://openalex.org/W2046616637","https://openalex.org/W114788794","https://openalex.org/W4380354169"],"abstract_inverted_index":{"Purpose:":[0],"A":[1],"novel":[2],"application":[3],"of":[4,17,163,237,254],"QuPath":[5,26,45,66,155,172,188,209,228,262],"open-source":[6],"digital":[7],"analysis":[8,16,210,236,253],"software":[9,27],"is":[10,229],"used":[11],"to":[12,30,136,184],"provide":[13],"in-depth":[14,252],"morphological":[15],"progressive":[18],"optic":[19],"nerve":[20],"(ON)":[21],"degeneration":[22],"in":[23,36,98,111,148,223],"rats.":[24],"Methods:":[25],"was":[28,140,197,258],"adapted":[29],"assess":[31],"axon":[32,46,77,81,124,129,156,181,213,215],"and":[33,51,59,74,84,110,178,218,239],"gliotic":[34,52,96,219],"morphology":[35,216],"toluidine":[37],"blue-stained,":[38],"Brown":[39],"Norway":[40],"rat":[41],"ON":[42,60,89,112,180,190,255],"light":[43],"micrographs.":[44],"numbers,":[47],"density,":[48,83],"size":[49],"distributions,":[50],"areas":[53,97],"were":[54,68,133],"obtained":[55],"from":[56],"test":[57,99,164,176],"images":[58,100,165,177],"cross-sections":[61,113],"separated":[62],"by":[63,260],"damage":[64],"grade.":[65],"results":[67],"compared":[69],"with":[70,87,95,160],"manual":[71,161],"counting,":[72],"AxonJ,":[73],"electron":[75,185],"microscopy":[76,186],"estimates.":[78],"Results:":[79],"QuPath-derived":[80],"number,":[82],"diameter":[85],"decreased":[86],"increasing":[88],"damage.":[90],"Axon":[91],"density":[92],"negatively":[93],"correlated":[94,158],"(R2":[101,114,166,199],"=":[102,108,115,121,167,200,206],"0.759;":[103],"P":[104,117,169,202],"<":[105,118,170,203],"0.0001;":[106],"N":[107,120,205],"40)":[109],"0.803;":[116],"0.0004;":[119],"10).":[122,207],"Although":[123],"losses":[125],"occurred":[126,222],"across":[127],"most":[128],"diameters,":[130],"large":[131],"axons":[132,142],"more":[134],"susceptible":[135],"degeneration.":[137],"The":[138],"exception":[139],"swollen":[141],">":[143],"2":[144],"\u00b5m,":[145],"which":[146],"increased":[147],"moderately":[149],"but":[150],"not":[151],"severely":[152],"damaged":[153],"images.":[154],"counts":[157,162],"strongly":[159],"0.956;":[168],"0.0001).":[171],"outperformed":[173],"AxonJ":[174],"on":[175,250],"total":[179],"counts.":[182],"Compared":[183],"analysis,":[187],"undercounted":[189],"axons;":[191],"however,":[192],"correlation":[193],"between":[194],"the":[195,261],"methods":[196],"robust":[198],"0.797;":[201],"0.001;":[204],"Conclusions:":[208],"reliably":[211],"identified":[212],"loss,":[214],"changes,":[217],"expansion":[220],"that":[221],"degenerating":[224,240],"ONs.":[225,241],"Translational":[226],"Relevance:":[227],"a":[230],"valuable":[231],"tool":[232],"for":[233,245],"rapid,":[234],"automated,":[235],"healthy":[238],"Reproducible":[242],"preclinical":[243],"studies":[244],"new":[246],"glaucoma":[247],"treatments":[248],"depend":[249],"unbiased":[251],"pathology.":[256],"This":[257],"provided":[259],"approach.":[263]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2020-03-06T00:00:00"}