{"id":"https://openalex.org/W3006567698","doi":"https://doi.org/10.1093/jmicro/dfz117","title":"Cellular network across cementum and periodontal ligament elucidated by FIB/SEM tomography","display_name":"Cellular network across cementum and periodontal ligament elucidated by FIB/SEM tomography","publication_year":2019,"publication_date":"2019-12-30","ids":{"openalex":"https://openalex.org/W3006567698","doi":"https://doi.org/10.1093/jmicro/dfz117","mag":"3006567698","pmid":"https://pubmed.ncbi.nlm.nih.gov/32047915"},"language":"en","primary_location":{"id":"doi:10.1093/jmicro/dfz117","doi":"https://doi.org/10.1093/jmicro/dfz117","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jmicro/dfz117","pdf_url":null,"source":{"id":"https://openalex.org/S4210174966","display_name":"Microscopy","issn_l":"2050-5698","issn":["2050-5698","2050-5701"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microscopy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027751005","display_name":"Shingo Hirashima","orcid":"https://orcid.org/0000-0002-6558-6482","observed_orcids":["https://orcid.org/0000-0002-6558-6482"]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]},{"id":"https://openalex.org/I4210097362","display_name":"Kurume University Medical Center","ror":"https://ror.org/00srtbf93","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210097362"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Shingo Hirashima","raw_affiliation_strings":["Dental and Oral Medical Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental and Oral Medical Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","institution_ids":["https://openalex.org/I105296287","https://openalex.org/I4210097362"]},{"raw_affiliation_string":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063369452","display_name":"Keisuke Ohta","orcid":"https://orcid.org/0000-0002-2040-5297","observed_orcids":["https://orcid.org/0000-0002-2040-5297"]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keisuke Ohta","raw_affiliation_strings":["Advanced Imaging Research Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Imaging Research Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","institution_ids":["https://openalex.org/I105296287"]},{"raw_affiliation_string":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110173511","display_name":"Tomonoshin Kanazawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomonoshin Kanazawa","raw_affiliation_strings":["Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075535491","display_name":"Akinobu Togo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akinobu Togo","raw_affiliation_strings":["Advanced Imaging Research Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Imaging Research Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083380312","display_name":"Risa Tsuneyoshi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Risa Tsuneyoshi","raw_affiliation_strings":["Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","institution_ids":["https://openalex.org/I105296287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037397895","display_name":"Jingo Kusukawa","orcid":"https://orcid.org/0000-0001-5556-9710","observed_orcids":["https://orcid.org/0000-0001-5556-9710"]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]},{"id":"https://openalex.org/I4210097362","display_name":"Kurume University Medical Center","ror":"https://ror.org/00srtbf93","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210097362"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jingo Kusukawa","raw_affiliation_strings":["Dental and Oral Medical Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental and Oral Medical Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","institution_ids":["https://openalex.org/I105296287","https://openalex.org/I4210097362"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016947629","display_name":"Kei\u2010ichiro Nakamura","orcid":"https://orcid.org/0000-0003-3438-9176","observed_orcids":["https://orcid.org/0000-0003-3438-9176"]},"institutions":[{"id":"https://openalex.org/I105296287","display_name":"Kurume University","ror":"https://ror.org/057xtrt18","country_code":"JP","type":"education","lineage":["https://openalex.org/I105296287"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kei-ichiro Nakamura","raw_affiliation_strings":["Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan","institution_ids":["https://openalex.org/I105296287"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5027751005"],"corresponding_institution_ids":["https://openalex.org/I105296287","https://openalex.org/I4210097362"],"apc_list":{"value":3494,"currency":"USD","value_usd":3494},"apc_paid":null,"fwci":0.883,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.73974044,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"69","issue":"1","first_page":"53","last_page":"58"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.6395999789237976,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.6395999789237976,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13552","display_name":"Advanced Materials Characterization Techniques","score":0.048900000751018524,"subfield":{"id":"https://openalex.org/subfields/2500","display_name":"General Materials Science"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10113","display_name":"Dental materials and restorations","score":0.0421999990940094,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cementum","display_name":"cementum","score":0.796999990940094},{"id":"https://openalex.org/keywords/periodontal-ligament","display_name":"periodontal ligament","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cementocytes","display_name":"cementocytes","score":0.8889999985694885},{"id":"https://openalex.org/keywords/cellular-networks","display_name":"cellular networks","score":0.8420000076293945},{"id":"https://openalex.org/keywords/three-dimensional-ultrastructure","display_name":"three-dimensional ultrastructure","score":0.8999999761581421},{"id":"https://openalex.org/keywords/fib-sem-tomography","display_name":"FIB-SEM tomography","score":0.8970000147819519},{"id":"https://openalex.org/keywords/periodontal-tissue-remodeling","display_name":"periodontal tissue remodeling","score":0.9259999990463257}],"concepts":[{"id":"https://openalex.org/C41868710","wikidata":"https://www.wikidata.org/wiki/Q540092","display_name":"Periodontal fiber","level":2,"score":0.9065872430801392},{"id":"https://openalex.org/C2777894202","wikidata":"https://www.wikidata.org/wiki/Q848382","display_name":"Cementum","level":3,"score":0.8858541250228882},{"id":"https://openalex.org/C2908931166","wikidata":"https://www.wikidata.org/wiki/Q848382","display_name":"Dental cementum","level":4,"score":0.595005214214325},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.42510244250297546},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.347788006067276},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3303254246711731},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.3291741609573364},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2937021255493164},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.13004851341247559},{"id":"https://openalex.org/C2779263046","wikidata":"https://www.wikidata.org/wiki/Q189637","display_name":"Dentin","level":2,"score":0.06413859128952026}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003739","descriptor_name":"Dental Cementum","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D003739","descriptor_name":"Dental Cementum","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/jmicro/dfz117","doi":"https://doi.org/10.1093/jmicro/dfz117","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jmicro/dfz117","pdf_url":null,"source":{"id":"https://openalex.org/S4210174966","display_name":"Microscopy","issn_l":"2050-5698","issn":["2050-5698","2050-5701"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microscopy","raw_type":"journal-article"},{"id":"pmid:32047915","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32047915","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microscopy (Oxford, England)","raw_type":"Letter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4363161317","display_name":"Morphological and telomere analysis of pathogenesis and prevention of lifestyle-related diseases due to fetal nutritional environment epigenomic changes","funder_award_id":"19K11733","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6508270909","display_name":"Comparison of Structural Properties Between Postnatal and Adult Tendon Insertion with FIB/SEM Tomography in Rat","funder_award_id":"17K11038","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6863999985","display_name":"Three dimensional ultrastructural analyses of the distribution pattern and dynamics of the interstitial cells in the connective tissues in the mammalian body.","funder_award_id":"20H03290","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8908628461","display_name":"An investigation into the formation processes of collagen bundles in periodontal ligament by innovative imaging methods","funder_award_id":"17K17090","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W107554693","https://openalex.org/W1965637518","https://openalex.org/W1968702538","https://openalex.org/W1970190964","https://openalex.org/W2019582558","https://openalex.org/W2037293673","https://openalex.org/W2038468016","https://openalex.org/W2067399788","https://openalex.org/W2085882515","https://openalex.org/W2097453212","https://openalex.org/W2099947313","https://openalex.org/W2123934184","https://openalex.org/W2128130529","https://openalex.org/W2131590798","https://openalex.org/W2150000732","https://openalex.org/W2175371769","https://openalex.org/W2334629724","https://openalex.org/W2404780642","https://openalex.org/W2416137505","https://openalex.org/W2564850197","https://openalex.org/W2605206416","https://openalex.org/W2883432742","https://openalex.org/W2884743503","https://openalex.org/W2906019782","https://openalex.org/W2953687684","https://openalex.org/W2972595996"],"related_works":["https://openalex.org/W3215248374","https://openalex.org/W2564850197","https://openalex.org/W2972595996","https://openalex.org/W2089793400","https://openalex.org/W2883432742","https://openalex.org/W1966052062","https://openalex.org/W2953687684","https://openalex.org/W3187058625","https://openalex.org/W2020893394","https://openalex.org/W2099934586"],"abstract_inverted_index":{"Cementocytes":[0],"in":[1],"cementum":[2,31],"form":[3],"a":[4,47,85],"lacuna-canalicular":[5],"network.":[6,63],"However,":[7],"the":[8,14,20,24,28,39,60,70,77],"3D":[9,21],"ultrastructure":[10,22],"and":[11,32,52,68,79],"range":[12],"of":[13,23,50,81,90],"cementocyte":[15,25],"network":[16,26,49],"are":[17],"unclear.":[18],"Here,":[19],"at":[27],"interface":[29],"between":[30],"periodontal":[33,82],"ligament":[34],"(PDL)":[35],"was":[36],"investigated":[37],"on":[38],"mesoscale":[40],"using":[41,84],"FIB/SEM":[42],"tomography.":[43],"The":[44],"results":[45],"revealed":[46,59,69],"cellular":[48,62,72],"cementocytes":[51],"PDL":[53],"cells.":[54],"A":[55],"previous":[56],"histomorphological":[57],"study":[58],"osteocyte-osteoblast-PDL":[61],"We":[64],"extended":[65],"this":[66],"knowledge":[67],"cementum-PDL-bone":[71],"network,":[73],"which":[74],"may":[75],"orchestrate":[76],"remodeling":[78],"modification":[80],"tissue,":[83],"suitable":[86],"method":[87],"for":[88],"imaging":[89],"complex":[91],"tissue.":[92]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2020-02-24T00:00:00"}