{"id":"https://openalex.org/W3003524924","doi":"https://doi.org/10.1007/s00109-020-01875-1","title":"Altered molecular signatures during kidney development after intrauterine growth restriction of different origins","display_name":"Altered molecular signatures during kidney development after intrauterine growth restriction of different origins","publication_year":2020,"publication_date":"2020-02-01","ids":{"openalex":"https://openalex.org/W3003524924","doi":"https://doi.org/10.1007/s00109-020-01875-1","mag":"3003524924","pmid":"https://pubmed.ncbi.nlm.nih.gov/32008055","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7080693"},"language":"en","primary_location":{"id":"doi:10.1007/s00109-020-01875-1","doi":"https://doi.org/10.1007/s00109-020-01875-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00109-020-01875-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00109-020-01875-1.pdf","source":{"id":"https://openalex.org/S114689480","display_name":"Journal of Molecular Medicine","issn_l":"0946-2716","issn":["0946-2716","1432-1440"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00109-020-01875-1.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012572131","display_name":"Eva N\u00fcsken","orcid":"https://orcid.org/0000-0002-0674-804X","observed_orcids":["https://orcid.org/0000-0002-0674-804X"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Eva N\u00fcsken","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0674-804X","affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047161890","display_name":"Gregor Fink","orcid":"https://orcid.org/0000-0001-7042-1706","observed_orcids":["https://orcid.org/0000-0001-7042-1706"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gregor Fink","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7042-1706","affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024218846","display_name":"Felix Lechner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Felix Lechner","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005194832","display_name":"Jenny Voggel","orcid":"https://orcid.org/0000-0001-9120-2203","observed_orcids":["https://orcid.org/0000-0001-9120-2203"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jenny Voggel","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":"https://orcid.org/0000-0001-9120-2203","affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030253900","display_name":"Maria Wohlfarth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Maria Wohlfarth","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lisa Sprenger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lisa Sprenger","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019372546","display_name":"Nava Mehdiani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Nava Mehdiani","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017241443","display_name":"Lutz Thorsten Weber","orcid":"https://orcid.org/0000-0003-4116-598X","observed_orcids":["https://orcid.org/0000-0003-4116-598X"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lutz T. Weber","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043321373","display_name":"Max C. Liebau","orcid":"https://orcid.org/0000-0003-0494-9080","observed_orcids":["https://orcid.org/0000-0003-0494-9080"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Max Christoph Liebau","raw_affiliation_strings":["Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany","Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]},{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007437036","display_name":"Bent Brachvogel","orcid":"https://orcid.org/0000-0002-3923-0554","observed_orcids":["https://orcid.org/0000-0002-3923-0554"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bent Brachvogel","raw_affiliation_strings":["Center for Biochemistry, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biochemistry, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]},{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044454219","display_name":"J\u00f6rg D\u00f6tsch","orcid":"https://orcid.org/0000-0003-1529-7647","observed_orcids":["https://orcid.org/0000-0003-1529-7647"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J\u00f6rg D\u00f6tsch","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074317604","display_name":"Kai\u2010Dietrich N\u00fcsken","orcid":"https://orcid.org/0000-0001-5749-7183","observed_orcids":["https://orcid.org/0000-0001-5749-7183"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Kai-Dietrich N\u00fcsken","raw_affiliation_strings":["Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany. kai-dietrich.nuesken@uk-koeln.de","Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany"],"raw_orcid":"https://orcid.org/0000-0001-5749-7183","affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany. kai-dietrich.nuesken@uk-koeln.de","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]},{"raw_affiliation_string":"Department of Pediatrics and Adolescent Medicine, University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5074317604"],"corresponding_institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"],"apc_list":{"value":3860,"currency":"USD","value_usd":3860},"apc_paid":{"value":3860,"currency":"USD","value_usd":3860},"fwci":4.8712,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.96410036,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"98","issue":"3","first_page":"395","last_page":"407"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.011099999770522118,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12140","display_name":"Renal and related cancers","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":0.9990000128746033},{"id":"https://openalex.org/keywords/kidney-development","display_name":"kidney development","score":0.8980000019073486},{"id":"https://openalex.org/keywords/renal-transcriptome","display_name":"renal transcriptome","score":0.6290000081062317},{"id":"https://openalex.org/keywords/low-protein-diet","display_name":"low-protein diet","score":0.781000018119812},{"id":"https://openalex.org/keywords/intrauterine-stress","display_name":"intrauterine stress","score":0.9739999771118164},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.5899999737739563},{"id":"https://openalex.org/keywords/ampk-signaling","display_name":"AMPK signaling","score":0.6399999856948853},{"id":"https://openalex.org/keywords/ppar-signaling-pathway","display_name":"PPAR signaling","score":0.9950000047683716},{"id":"https://openalex.org/keywords/rictor","display_name":"Rictor","score":0.8429999947547913},{"id":"https://openalex.org/keywords/mtor-signaling","display_name":"mTOR signaling","score":0.8700000047683716},{"id":"https://openalex.org/keywords/neonatal-rats","display_name":"neonatal rats","score":0.5450000166893005}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6113185286521912},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.6026349067687988},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5712271332740784},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5366494059562683},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4926624894142151},{"id":"https://openalex.org/C2778780700","wikidata":"https://www.wikidata.org/wiki/Q1671598","display_name":"Intrauterine growth restriction","level":4,"score":0.48199811577796936},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4025294780731201},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2224145233631134},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19517159461975098},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.12509992718696594},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.12497106194496155},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12258952856063843}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005317","descriptor_name":"Fetal Growth Retardation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1007/s00109-020-01875-1","doi":"https://doi.org/10.1007/s00109-020-01875-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00109-020-01875-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00109-020-01875-1.pdf","source":{"id":"https://openalex.org/S114689480","display_name":"Journal of Molecular Medicine","issn_l":"0946-2716","issn":["0946-2716","1432-1440"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7080693","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7080693","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Mol Med (Berl)","raw_type":"Text"},{"id":"pmid:32008055","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32008055","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular medicine (Berlin, Germany)","raw_type":"Journal Article"},{"id":"pmh:oai:USBKOELN.ub.uni-koeln.de:34766","doi":null,"is_oa":false,"landing_page_url":"https://kups.ub.uni-koeln.de/34766/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400371","display_name":"K\u00f6lner Universit\u00e4ts PublikationsServer (Universit\u00e4t zu K\u00f6ln)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115942","host_organization_name":"Rhenish Institute for Environmental Research","host_organization_lineage":["https://openalex.org/I4210115942"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"doc-type:article"},{"id":"pmh:oai:frl.publisso.de:frl:6441543","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7080693","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7080693/pdf/109_2020_Article_1875.pdf","source":{"id":"https://openalex.org/S4306402606","display_name":"Informationszentrum Lebenswissenschaften (ZB MED)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210112663","host_organization_name":"ZB MED - Information Centre for Life Sciences","host_organization_lineage":["https://openalex.org/I4210112663"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of molecular medicine, 98(3):395-407","raw_type":"Zeitschriftenartikel"}],"best_oa_location":{"id":"doi:10.1007/s00109-020-01875-1","doi":"https://doi.org/10.1007/s00109-020-01875-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00109-020-01875-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00109-020-01875-1.pdf","source":{"id":"https://openalex.org/S114689480","display_name":"Journal of Molecular Medicine","issn_l":"0946-2716","issn":["0946-2716","1432-1440"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1932864825","display_name":null,"funder_award_id":"#NU-137/3-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3003524924.pdf","grobid_xml":"https://content.openalex.org/works/W3003524924.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1963528868","https://openalex.org/W1968272943","https://openalex.org/W1972339030","https://openalex.org/W1973002697","https://openalex.org/W1973268693","https://openalex.org/W1978431700","https://openalex.org/W1986332831","https://openalex.org/W2017507345","https://openalex.org/W2023853426","https://openalex.org/W2047632739","https://openalex.org/W2049845437","https://openalex.org/W2065786310","https://openalex.org/W2069186037","https://openalex.org/W2072765855","https://openalex.org/W2073212969","https://openalex.org/W2075623847","https://openalex.org/W2083898397","https://openalex.org/W2100695272","https://openalex.org/W2105701104","https://openalex.org/W2107837933","https://openalex.org/W2109181554","https://openalex.org/W2111455859","https://openalex.org/W2123938699","https://openalex.org/W2125308882","https://openalex.org/W2132653759","https://openalex.org/W2139020475","https://openalex.org/W2142062298","https://openalex.org/W2143508168","https://openalex.org/W2162997059","https://openalex.org/W2167712860","https://openalex.org/W2257962987","https://openalex.org/W2261897967","https://openalex.org/W2273738635","https://openalex.org/W2310682570","https://openalex.org/W2331503091","https://openalex.org/W2339931277","https://openalex.org/W2415080161","https://openalex.org/W2506283615","https://openalex.org/W2537623931","https://openalex.org/W2552808209","https://openalex.org/W2582613914","https://openalex.org/W2597465653","https://openalex.org/W2605358691","https://openalex.org/W2769908428","https://openalex.org/W2790245860","https://openalex.org/W2943833093","https://openalex.org/W2945316679"],"related_works":["https://openalex.org/W7016079918","https://openalex.org/W4389019842","https://openalex.org/W1968272943","https://openalex.org/W2767668404","https://openalex.org/W2057549159","https://openalex.org/W2062014008","https://openalex.org/W4388861284","https://openalex.org/W2793882588","https://openalex.org/W4286215777","https://openalex.org/W3019783586"],"abstract_inverted_index":{"This":[0],"study":[1],"was":[2,36,68,88],"performed":[3],"to":[4,24,31],"identify":[5],"transcriptional":[6],"alterations":[7],"in":[8,22,193,212,238,256,268],"male":[9],"intrauterine":[10,51],"growth":[11],"restricted":[12],"(IUGR)":[13],"rats":[14],"during":[15],"and":[16,107,129,141,145,160,184,202,205,209,242,290],"at":[17,189],"the":[18,227],"end":[19],"of":[20,58,77,177,182,207,226,236,259],"nephrogenesis":[21],"order":[23],"generate":[25],"hypotheses":[26],"which":[27],"molecular":[28,168],"mechanisms":[29],"contribute":[30],"adverse":[32],"kidney":[33,66,222,254],"programming.":[34],"IUGR":[35,135,176,260,270],"induced":[37],"by":[38,54,71,90],"low":[39,280,287],"protein":[40,281,288],"(LP)":[41],"diet":[42,289],"throughout":[43],"pregnancy,":[44],"bilateral":[45],"uterine":[46,291],"vessel":[47,292],"ligation":[48],"(LIG),":[49],"or":[50,81],"stress":[52],"(IUS)":[53],"sham":[55],"operation.":[56],"Offspring":[57],"unimpaired":[59],"dams":[60],"served":[61],"as":[62,150,152],"controls.":[63],"Significant":[64],"acute":[65],"damage":[67],"ruled":[69],"out":[70],"negative":[72],"results":[73],"for":[74],"proteins":[75],"indicative":[76],"ER-stress,":[78],"autophagy,":[79],"apoptosis,":[80],"infiltration":[82],"with":[83],"macrophages.":[84],"Renal":[85],"gene":[86],"expression":[87],"examined":[89],"transcriptome":[91],"microarrays,":[92],"demonstrating":[93],"53":[94],"(LP,":[95,109],"n":[96,100,104,110,114,118],"=":[97,101,105,111,115,119],"12;":[98],"LIG,":[99,113,142],"32;":[102],"IUS,":[103,117],"9)":[106],"134":[108],"10;":[112],"41;":[116],"83)":[120],"differentially":[121],"expressed":[122],"transcripts":[123,183,265],"on":[124],"postnatal":[125],"days":[126],"(PND)":[127],"1":[128],"7,":[130],"respectively.":[131],"Reduced":[132],"Pilra":[133],"(all":[134],"groups,":[136],"PND":[137,143,148,157,163],"7),":[138,144],"Nupr1":[139],"(LP":[140],"Kap":[146],"(LIG,":[147,156],"1)":[149],"well":[151],"increased":[153],"Ccl20,":[154],"S100a8/a9":[155],"1),":[158,246],"Ifna4,":[159],"Ltb4r2":[161],"(IUS,":[162],"7)":[164,241],"indicated":[165],"that":[166,248],"inflammation-related":[167],"dysregulation":[169,206,235,278],"could":[170,251],"be":[171],"a":[172],"\"common\"":[173],"feature":[174],"after":[175,279,286],"different":[178],"origins.":[179],"Network":[180],"analyses":[181,274],"predicted":[185,230],"upstream":[186,231],"regulators":[187,232],"hinted":[188],"proinflammatory":[190],"adaptions":[191],"mainly":[192],"LIG":[194,243],"(arachidonic":[195],"acid-binding,":[196],"neutrophil":[197],"aggregation,":[198],"toll-like-receptor,":[199],"NF-kappa":[200],"B,":[201],"TNF":[203],"signaling)":[204],"AMPK":[208],"PPAR":[210],"signaling":[211],"LP":[213,239],"pups.":[214,261],"The":[215],"latter":[216],"may":[217],"increase":[218],"susceptibility":[219],"towards":[220],"obesity-associated":[221],"damage.":[223],"Western":[224],"blots":[225],"most":[228],"prominent":[229],"confirmed":[233],"significant":[234],"RICTOR":[237,283],"(PND":[240,245],"pups":[244],"suggesting":[247],"mTOR-related":[249],"processes":[250],"further":[252],"modulate":[253],"programming":[255],"these":[257],"groups":[258],"KEY":[262],"MESSAGES:":[263],"Inflammation-related":[264],"are":[266],"dysregulated":[267,285],"neonatal":[269],"rat":[271],"kidneys.":[272],"Upstream":[273],"indicate":[275],"renal":[276],"metabolic":[277],"diet.":[282],"is":[284],"ligation.":[293]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":10}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-02-07T00:00:00"}