{"id":"https://openalex.org/W3002014246","doi":"https://doi.org/10.1002/jgc4.1219","title":"Referencing BRCA in hereditary cancer risk discussions: In search of an anchor in a sea of uncertainty","display_name":"Referencing BRCA in hereditary cancer risk discussions: In search of an anchor in a sea of uncertainty","publication_year":2020,"publication_date":"2020-01-22","ids":{"openalex":"https://openalex.org/W3002014246","doi":"https://doi.org/10.1002/jgc4.1219","mag":"3002014246","pmid":"https://pubmed.ncbi.nlm.nih.gov/31967382"},"language":"en","primary_location":{"id":"doi:10.1002/jgc4.1219","doi":"https://doi.org/10.1002/jgc4.1219","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jgc4.1219","pdf_url":null,"source":{"id":"https://openalex.org/S99574856","display_name":"Journal of Genetic Counseling","issn_l":"1059-7700","issn":["1059-7700","1573-3599"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Genetic Counseling","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7374021","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044093264","display_name":"Margaret Waltz","orcid":"https://orcid.org/0000-0002-2582-145X","observed_orcids":["https://orcid.org/0000-0002-2582-145X"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Margaret Waltz","raw_affiliation_strings":["Department of Social Medicine University of North Carolina at Chapel Hill Chapel Hill North Carolina","Department of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"],"raw_orcid":"https://orcid.org/0000-0002-2582-145X","affiliations":[{"raw_affiliation_string":"Department of Social Medicine University of North Carolina at Chapel Hill Chapel Hill North Carolina","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025907276","display_name":"Anya E. R. Prince","orcid":"https://orcid.org/0000-0002-0086-7881","observed_orcids":["https://orcid.org/0000-0002-0086-7881"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anya E. R. Prince","raw_affiliation_strings":["University of Iowa College of Law Iowa City Iowa","University of Iowa College of Law, Iowa City, Iowa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Iowa College of Law Iowa City Iowa","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"University of Iowa College of Law, Iowa City, Iowa","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047038540","display_name":"Julianne M. O\u2019Daniel","orcid":"https://orcid.org/0000-0001-5843-4432","observed_orcids":["https://orcid.org/0000-0001-5843-4432"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julianne M. O'Daniel","raw_affiliation_strings":["Department of Genetics University of North Carolina at Chapel Hill Chapel Hill North Carolina","Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics University of North Carolina at Chapel Hill Chapel Hill North Carolina","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074610995","display_name":"Ann Katherine M. Foreman","orcid":"https://orcid.org/0000-0002-0293-6609","observed_orcids":["https://orcid.org/0000-0002-0293-6609"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ann Katherine M. Foreman","raw_affiliation_strings":["Department of Genetics University of North Carolina at Chapel Hill Chapel Hill North Carolina","Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics University of North Carolina at Chapel Hill Chapel Hill North Carolina","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001077963","display_name":"Bradford C. Powell","orcid":"https://orcid.org/0000-0002-2842-8645","observed_orcids":["https://orcid.org/0000-0002-2842-8645"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bradford C. Powell","raw_affiliation_strings":["Department of Genetics University of North Carolina at Chapel Hill Chapel Hill North Carolina","Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics University of North Carolina at Chapel Hill Chapel Hill North Carolina","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028470777","display_name":"Jonathan S. Berg","orcid":"https://orcid.org/0000-0003-2360-2664","observed_orcids":["https://orcid.org/0000-0003-2360-2664"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan S. Berg","raw_affiliation_strings":["Department of Genetics University of North Carolina at Chapel Hill Chapel Hill North Carolina","Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics University of North Carolina at Chapel Hill Chapel Hill North Carolina","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5044093264"],"corresponding_institution_ids":["https://openalex.org/I114027177"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.3921,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.55548465,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"29","issue":"6","first_page":"949","last_page":"959"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10827","display_name":"Patient-Provider Communication in Healthcare","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brca1","display_name":"BRCA1","score":0.9829999804496765},{"id":"https://openalex.org/keywords/brca2","display_name":"BRCA2","score":1.0},{"id":"https://openalex.org/keywords/hereditary-breast-cancer","display_name":"hereditary breast cancer","score":0.828000009059906},{"id":"https://openalex.org/keywords/genetic-risk-communication","display_name":"genetic risk communication","score":0.6660000085830688},{"id":"https://openalex.org/keywords/return-of-results","display_name":"return of results","score":0.6259999871253967},{"id":"https://openalex.org/keywords/whole-exome-sequencing","display_name":"exome sequencing","score":0.7639999985694885},{"id":"https://openalex.org/keywords/panel-testing","display_name":"panel testing","score":0.7139999866485596},{"id":"https://openalex.org/keywords/external-anchors","display_name":"external anchors","score":0.4269999861717224},{"id":"https://openalex.org/keywords/uncertainty","display_name":"uncertainty","score":0.4560000002384186},{"id":"https://openalex.org/keywords/risk-perception","display_name":"risk perception","score":0.48399999737739563},{"id":"https://openalex.org/keywords/breast-cancer-susceptibility-genes","display_name":"breast cancer susceptibility genes","score":0.6050000190734863},{"id":"https://openalex.org/keywords/patient-understanding","display_name":"patient understanding","score":0.44600000977516174}],"concepts":[{"id":"https://openalex.org/C200544954","wikidata":"https://www.wikidata.org/wiki/Q516389","display_name":"Penetrance","level":4,"score":0.7385337352752686},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7015721201896667},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.695176362991333},{"id":"https://openalex.org/C16671776","wikidata":"https://www.wikidata.org/wiki/Q5420592","display_name":"Exome sequencing","level":4,"score":0.648551344871521},{"id":"https://openalex.org/C80227256","wikidata":"https://www.wikidata.org/wiki/Q1124169","display_name":"Genetic counseling","level":2,"score":0.5964717268943787},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5662977695465088},{"id":"https://openalex.org/C2780673598","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic testing","level":2,"score":0.5409762263298035},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4766557812690735},{"id":"https://openalex.org/C10590036","wikidata":"https://www.wikidata.org/wiki/Q417664","display_name":"Exome","level":5,"score":0.424611896276474},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.3973575234413147},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20248571038246155},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17874115705490112},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.17336100339889526},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11094379425048828},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019398","descriptor_name":"Genes, BRCA1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019398","descriptor_name":"Genes, BRCA1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019398","descriptor_name":"Genes, BRCA1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019398","descriptor_name":"Genes, BRCA1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D024522","descriptor_name":"Genes, BRCA2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D024522","descriptor_name":"Genes, BRCA2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D024522","descriptor_name":"Genes, BRCA2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D024522","descriptor_name":"Genes, BRCA2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/jgc4.1219","doi":"https://doi.org/10.1002/jgc4.1219","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jgc4.1219","pdf_url":null,"source":{"id":"https://openalex.org/S99574856","display_name":"Journal of Genetic Counseling","issn_l":"1059-7700","issn":["1059-7700","1573-3599"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Genetic Counseling","raw_type":"journal-article"},{"id":"pmid:31967382","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31967382","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of genetic counseling","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7374021","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7374021","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Genet Couns","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7374021","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7374021","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Genet Couns","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.5299999713897705,"id":"https://metadata.un.org/sdg/14","display_name":"Life below water"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1581081233","display_name":null,"funder_award_id":"U01 HG006487","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G3745309493","display_name":null,"funder_award_id":"R00HG008819","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G798506169","display_name":null,"funder_award_id":"P50HG004488","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G9000054446","display_name":null,"funder_award_id":"U01HG006487","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000242150","display_name":null,"funder_award_id":"R00HG008819","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000249811","display_name":null,"funder_award_id":"2P50HG004488","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000913976","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA016086","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W158727920","https://openalex.org/W1525438999","https://openalex.org/W1971830129","https://openalex.org/W1989404815","https://openalex.org/W2017404031","https://openalex.org/W2027602671","https://openalex.org/W2035544190","https://openalex.org/W2040410805","https://openalex.org/W2042651776","https://openalex.org/W2077977578","https://openalex.org/W2126829330","https://openalex.org/W2129507083","https://openalex.org/W2141333959","https://openalex.org/W2142225512","https://openalex.org/W2153589369","https://openalex.org/W2163072999","https://openalex.org/W2167564136","https://openalex.org/W2268475462","https://openalex.org/W2425061965","https://openalex.org/W2466675502","https://openalex.org/W2507497916","https://openalex.org/W2514946118","https://openalex.org/W2531500998","https://openalex.org/W2565719646","https://openalex.org/W2605529594","https://openalex.org/W2605654091","https://openalex.org/W2609144831","https://openalex.org/W2627871710","https://openalex.org/W2767561639","https://openalex.org/W2781848254","https://openalex.org/W2783613967","https://openalex.org/W2787986226","https://openalex.org/W2802042353","https://openalex.org/W2802834623","https://openalex.org/W2861740549","https://openalex.org/W2885654189","https://openalex.org/W2886678486","https://openalex.org/W2900898778","https://openalex.org/W2902403392","https://openalex.org/W2902577499","https://openalex.org/W2906781593","https://openalex.org/W2914497288","https://openalex.org/W2918403504","https://openalex.org/W4239330620","https://openalex.org/W4292157289","https://openalex.org/W4300497086"],"related_works":["https://openalex.org/W1966322871","https://openalex.org/W2093932542","https://openalex.org/W2538130930","https://openalex.org/W4210704068","https://openalex.org/W4376872152","https://openalex.org/W4323293767","https://openalex.org/W2142174838","https://openalex.org/W2043256480","https://openalex.org/W2059304053","https://openalex.org/W2057624627"],"abstract_inverted_index":{"As":[0],"panel":[1],"testing":[2],"and":[3,21,30,42,54,89,116,142,156,175],"exome":[4,68],"sequencing":[5,69],"are":[6],"increasingly":[7],"incorporated":[8],"into":[9],"clinical":[10],"care,":[11],"clinicians":[12,125,162],"must":[13],"grapple":[14],"with":[15,195],"how":[16,159],"to":[17,44,132,148,164,222],"communicate":[18],"the":[19,55,64,121,133,160,185,216],"risks":[20],"treatment":[22],"decisions":[23],"surrounding":[24],"breast":[25,87,138],"cancer":[26,52,96,219],"genes":[27],"beyond":[28],"BRCA1":[29,41,115,141,174],"BRCA2.":[31],"In":[32],"this":[33,59],"paper,":[34],"we":[35],"examine":[36],"clinicians'":[37],"practice":[38,60],"of":[39,58,66,75,92,109,136,152,180,187,193,197,215,218],"employing":[40],"BRCA2":[43,117,143,176],"help":[45],"contextualize":[46],"less":[47],"certain":[48],"genetic":[49,153],"information":[50,161],"regarding":[51,106],"risk":[53,186,194,198],"possible":[56],"implications":[57],"for":[61,78,203],"patients":[62,99,165,188],"within":[63],"context":[65],"an":[67,169],"study,":[70],"NCGENES.":[71],"We":[72,112],"audio-recorded":[73],"return":[74],"results":[76],"appointments":[77],"14":[79],"women":[80],"who":[81],"participated":[82],"in":[83,229],"NCGENES,":[84],"previously":[85],"had":[86],"cancer,":[88],"were":[90,100,118,144],"suspected":[91],"having":[93],"a":[94,178,201,204],"hereditary":[95],"predisposition.":[97],"These":[98],"also":[101],"interviewed":[102],"four":[103],"weeks":[104],"later":[105],"their":[107,110],"understanding":[108,135],"results.":[111],"found":[113],"that":[114],"held":[119],"as":[120,146,168,177],"gold":[122],"standard,":[123],"where":[124],"compared":[126],"what":[127],"is":[128],"known":[129],"about":[130,191],"BRCA":[131],"limited":[134],"other":[137,225],"cancer-related":[139],"genes.":[140],"used":[145],"anchors":[147],"shape":[149],"patients'":[150],"understandings":[151],"knowledge,":[154],"risk,":[155],"management,":[157],"illustrating":[158],"provide":[163],"may":[166],"work":[167],"external":[170],"anchor.":[171],"Yet,":[172],"presenting":[173],"means":[179],"scientific":[181],"reassurance":[182],"can":[183,209],"run":[184],"conflating":[189],"knowledge":[190],"certainty":[192],"degree":[196],"after":[199],"receiving":[200],"result":[202],"moderate":[205],"penetrance":[206],"gene.":[207],"This":[208],"be":[210],"further":[211],"complicated":[212],"by":[213],"misperceptions":[214],"precision":[217],"predictability":[220],"attributed":[221],"these":[223],"or":[224],"described":[226],"'cancer":[227],"genes'":[228],"public":[230],"media.":[231]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-15T10:00:46.086208","created_date":"2020-01-30T00:00:00"}