{"id":"https://openalex.org/W3001206975","doi":"https://doi.org/10.1016/j.bbmt.2019.12.379","title":"Allogeneic Viral Specific T Cells Are Safe and Can be Efficient in the Treatment of Infections in Solid Organ Transplant Recipients","display_name":"Allogeneic Viral Specific T Cells Are Safe and Can be Efficient in the Treatment of Infections in Solid Organ Transplant Recipients","publication_year":2020,"publication_date":"2020-01-23","ids":{"openalex":"https://openalex.org/W3001206975","doi":"https://doi.org/10.1016/j.bbmt.2019.12.379","mag":"3001206975"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbmt.2019.12.379","doi":"https://doi.org/10.1016/j.bbmt.2019.12.379","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2019.12.379","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.bbmt.2019.12.379","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103795351","display_name":"Adam Stuart Nelson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam S. Nelson","raw_affiliation_strings":["Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060325467","display_name":"Teri Clark","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Teri Clark","raw_affiliation_strings":["Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053753214","display_name":"Diana Clark","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diana Clark","raw_affiliation_strings":["Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091512019","display_name":"Olivia Grimley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivia Grimley","raw_affiliation_strings":["Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041199901","display_name":"Jeremy D. Rubinstein","orcid":"https://orcid.org/0000-0002-1934-2954","observed_orcids":["https://orcid.org/0000-0002-1934-2954"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremy D. Rubinstein","raw_affiliation_strings":["Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100939754","display_name":"Xiang Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiang Zhu","raw_affiliation_strings":["Experimental Hematology, Translational Core Laboratories, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Hematology, Translational Core Laboratories, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038018937","display_name":"Jamie Wilhelm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jamie Wilhelm","raw_affiliation_strings":["Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006134549","display_name":"Catherine M. Bollard","orcid":"https://orcid.org/0000-0001-5140-9090","observed_orcids":["https://orcid.org/0000-0001-5140-9090"]},"institutions":[{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine M. Bollard","raw_affiliation_strings":["Center for Cancer and Immunology Research, Children's National Medical Center, Washington, DC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Cancer and Immunology Research, Children's National Medical Center, Washington, DC","institution_ids":["https://openalex.org/I1336742384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066139971","display_name":"Patrick J. Hanley","orcid":"https://orcid.org/0000-0002-0102-7892","observed_orcids":["https://orcid.org/0000-0002-0102-7892"]},"institutions":[{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick J. Hanley","raw_affiliation_strings":["Center for Cancer and Immunology Research, Children's National Health System, Washington, DC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Cancer and Immunology Research, Children's National Health System, Washington, DC","institution_ids":["https://openalex.org/I1336742384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017322945","display_name":"Michael Daniel Keller","orcid":"https://orcid.org/0000-0001-8323-3085","observed_orcids":["https://orcid.org/0000-0001-8323-3085"]},"institutions":[{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael D. Keller","raw_affiliation_strings":["Center for Cancer and Immunology Research, Children's National Health System, Washington, DC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Cancer and Immunology Research, Children's National Health System, Washington, DC","institution_ids":["https://openalex.org/I1336742384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073333838","display_name":"Jos\u00e9 A. Cancelas","orcid":"https://orcid.org/0000-0002-1291-7233","observed_orcids":["https://orcid.org/0000-0002-1291-7233"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose A. Cancelas","raw_affiliation_strings":["Experimental Hematology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Hematology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028145044","display_name":"Stella M. Davies","orcid":"https://orcid.org/0000-0002-3137-6647","observed_orcids":["https://orcid.org/0000-0002-3137-6647"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stella M. Davies","raw_affiliation_strings":["Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021982985","display_name":"Carolyn Lutzko","orcid":"https://orcid.org/0009-0001-6266-3470","observed_orcids":["https://orcid.org/0009-0001-6266-3470"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carolyn Lutzko","raw_affiliation_strings":["Experimental Hematology, Translational Core Laboratories, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Hematology, Translational Core Laboratories, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031592776","display_name":"Michael S. Grimley","orcid":"https://orcid.org/0000-0003-2056-5167","observed_orcids":["https://orcid.org/0000-0003-2056-5167"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael S. Grimley","raw_affiliation_strings":["Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH","institution_ids":["https://openalex.org/I1285204247"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.00860182,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"26","issue":"3","first_page":"S344","last_page":"S345"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.5371000170707703,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.5371000170707703,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.2451999932527542,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.04809999838471413,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/solid-organ-transplant-recipients","display_name":"solid organ transplant recipients","score":0.9269999861717224},{"id":"https://openalex.org/keywords/cytomegalovirus-infection","display_name":"cytomegalovirus infection","score":0.906000018119812},{"id":"https://openalex.org/keywords/adenovirus-infection","display_name":"adenovirus infection","score":0.972000002861023},{"id":"https://openalex.org/keywords/bk-polyomavirus","display_name":"BK virus","score":0.7820000052452087},{"id":"https://openalex.org/keywords/hla-matching","display_name":"HLA matching","score":0.6620000004768372},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.8349999785423279},{"id":"https://openalex.org/keywords/viral-reactivation","display_name":"viral reactivation","score":0.41999998688697815},{"id":"https://openalex.org/keywords/heart-transplantation","display_name":"heart transplantation","score":0.4059999883174896},{"id":"https://openalex.org/keywords/liver-transplantation","display_name":"liver transplantation","score":0.8870000243186951},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/lung-transplantation","display_name":"lung transplantation","score":0.996999979019165},{"id":"https://openalex.org/keywords/tacrolimus","display_name":"tacrolimus","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9371822476387024},{"id":"https://openalex.org/C3018513187","wikidata":"https://www.wikidata.org/wiki/Q712378","display_name":"Solid organ","level":4,"score":0.8788257837295532},{"id":"https://openalex.org/C168444539","wikidata":"https://www.wikidata.org/wiki/Q105196","display_name":"Organ transplantation","level":3,"score":0.584607720375061},{"id":"https://openalex.org/C2994541485","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral infection","level":3,"score":0.4211009740829468},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.41179633140563965},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3720459043979645},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3454515337944031},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.3031937777996063},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16609618067741394},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.08303168416023254}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bbmt.2019.12.379","doi":"https://doi.org/10.1016/j.bbmt.2019.12.379","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2019.12.379","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bbmt.2019.12.379","doi":"https://doi.org/10.1016/j.bbmt.2019.12.379","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2019.12.379","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4392391458","https://openalex.org/W4394958522","https://openalex.org/W4402842815","https://openalex.org/W3184692748","https://openalex.org/W7204769327","https://openalex.org/W4254669094","https://openalex.org/W2555695588","https://openalex.org/W2799478363","https://openalex.org/W2744246163","https://openalex.org/W4399553403"],"abstract_inverted_index":{"Introduction":[0],"Recipients":[2],"of":[3,11,16,77,98,116,123,126,136,159,171,276,291,294,303,308,332,363,407,409,424,452],"solid":[4],"organ":[5,26,35,51],"transplant":[6],"(SOT)":[7],"are":[8,29,106,456],"at":[9,336],"risk":[10],"viral":[12,54,63,102,168,217,312,360,432],"infection":[13,49],"and":[14,34,37,69,81,101,154,180,195,260,267,285,296,345,371,436,443,465,472],"development":[15],"viral-driven":[17],"malignancy":[18],"(EBV-PTLD)":[19],"due":[20],"to":[21,24,41,61,166,185,193,201,240,311,325,338,349,359,391,427,449,458,467],"immunosuppressive":[22,146],"medications":[23],"prevent":[25],"rejection.":[27,52],"Treatments":[28],"limited":[30],"by":[31],"poor":[32],"efficacy":[33],"toxicity,":[36],"reduction":[38],"in":[39,83,104,316,357,396,438,441],"immunosuppression":[40],"enable":[42],"the":[43,48,75,114,177,243,249,273,289,292,304,364,388,392,397,405],"patient's":[44],"immune":[45,300],"system":[46],"fight":[47],"risks":[50],"Allogeneic":[53],"specific":[55],"T-cells":[56],"(VST)":[57],"have":[58,161],"been":[59],"used":[60],"treat":[62,167],"infections":[64,433],"after":[65,242,248],"stem":[66],"cell":[67],"transplant,":[68,266],"here":[70],"we":[71],"evaluated":[72,315],"VST":[73,117,178,224,426,463],"for":[74,343,369,474],"treatment":[76,204,447],"CMV,":[78],"ADV,":[79],"EBV-PTLD":[80],"BK":[82,370],"six":[84],"SOT":[85,428],"(heart,":[86],"liver,":[87],"kidney,":[88],"lung)":[89],"recipients.":[90],"Methods":[94],"Clinical":[96],"descriptors":[97],"diagnosis,":[99],"therapy":[100],"load":[103],"patients":[105,119,160,214,271,320],"presented.":[107],"Results":[111],"At":[113],"time":[115],"infusion,":[118],"were":[120,141,190,286,395],"a":[121,220,238,254,329,383],"median":[122],"16":[124],"years":[125,138],"age":[127],"(range":[128,170],"2":[129,261,365],"-":[130],"69":[131],"years)":[132],"with":[133,207,272,347,462],"an":[134,376],"average":[135],"5":[137],"post-SOT.":[139],"Patients":[140],"on":[142,149],"one":[143,234],"or":[144,219,280,373,399],"more":[145],"medications,":[147],"including":[148],"Tacrolimus":[150,268],"(3),":[151],"prednisolone":[152],"(4)":[153],"hydrocortisone":[155],"(2).":[156],"The":[157,173,203,226,306],"majority":[158],"received":[162],"multiple":[163,231],"monthly":[164],"infusions":[165,232],"disease":[169,218],"1-8).":[172],"HLA":[174],"match":[175,256],"between":[176],"unit":[179],"recipient":[181],"ranged":[182],"from":[183,191,199,318,431],"4/10":[184],"6/10.":[186],"Class":[187,196],"I":[188,259],"matches":[189,198],"0/6":[192],"3/6,":[194],"II":[197,263],"1/4":[200],"4/4.":[202],"was":[205,228,314,328,434],"safe":[206,435],"no":[208],"serious":[209],"adverse":[210],"events":[211],"observed.":[212],"All":[213],"had":[215,253,282,375],"stable":[216],"clinical":[221,384,393,439,460],"response":[222,227,239,295,358,385,394,461],"following":[223],"infusion.":[225],"sustained":[229],"over":[230,379],"except":[233],"patient":[235,252],"who":[236],"showed":[237],"CMV":[241,344],"first":[244],"infusion":[245,342,470],"but":[246],"not":[247,287],"second.":[250],"This":[251],"5/10":[255],"(3":[257],"class":[258,262],"match),":[264],"liver":[265],"treatment.":[269],"Other":[270],"same":[274],"degree":[275],"match,":[277],"virus":[278],"infection,":[279],"immunosuppressant":[281],"continued":[283],"responses":[284,440],"likely":[288],"cause":[290],"loss":[293],"therefore":[297],"could":[298],"be":[299],"mediated":[301],"rejection":[302],"VST.":[305],"presence":[307],"cells":[309,334,356,389],"responding":[310,333],"peptides":[313],"PBMC":[317],"five":[319],"using":[321],"IFNg":[322],"ELIspot.":[323],"Compared":[324],"pre-infusion,":[326],"there":[327],"higher":[330],"number":[331],"circulating":[335],"up":[337],"4":[339],"weeks":[340],"post-VST":[341],"ADV":[346],"129":[348],"852":[350],"spots":[351,378,411],"1\u202f\u00d7\u202f105":[352,413],"peripheral":[353,414],"blood":[354,415],"mononuclear":[355,416],"peptide.":[361],"Neither":[362],"kidney":[366],"recipients":[367,429,442],"treated":[368],"EBV,":[372],"EBV-PTDL":[374],"increase":[377],"background":[380],"despite":[381,402],"showing":[382],"suggesting":[386],"that":[387],"contributing":[390],"tissues":[398],"still":[400],"active":[401],"being":[403],"below":[404],"level":[406],"detection":[408],"10":[410],"per":[412],"cells.":[417],"Conclusion":[421],"Infusion":[423],"allogeneic":[425],"suffering":[430],"resulted":[437],"may":[444],"offer":[445],"additional":[446],"options":[448],"this":[450],"group":[451],"patients.":[453],"Further":[454],"data":[455],"needed":[457],"correlate":[459],"activity":[464],"persistence":[466],"optimize":[468],"future":[469],"schedules":[471],"allow":[473],"optimal":[475],"dosing.":[476]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2020-01-30T00:00:00"}