{"id":"https://openalex.org/W3000905340","doi":"https://doi.org/10.1007/s12247-019-09424-1","title":"Micronization and Agglomeration: Understanding the Impact of API Particle Properties on Dissolution and Permeability Using Solid State and Biopharmaceutical \u201cToolbox\u201d","display_name":"Micronization and Agglomeration: Understanding the Impact of API Particle Properties on Dissolution and Permeability Using Solid State and Biopharmaceutical \u201cToolbox\u201d","publication_year":2020,"publication_date":"2020-01-22","ids":{"openalex":"https://openalex.org/W3000905340","doi":"https://doi.org/10.1007/s12247-019-09424-1","mag":"3000905340"},"language":"en","primary_location":{"id":"doi:10.1007/s12247-019-09424-1","doi":"https://doi.org/10.1007/s12247-019-09424-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12247-019-09424-1","pdf_url":null,"source":{"id":"https://openalex.org/S168111969","display_name":"Journal of Pharmaceutical Innovation","issn_l":"1872-5120","issn":["1872-5120","1939-8042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Innovation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101574451","display_name":"Devarajan Saravanan","orcid":"https://orcid.org/0000-0003-0725-6079","observed_orcids":["https://orcid.org/0000-0003-0725-6079"]},"institutions":[{"id":"https://openalex.org/I4210138224","display_name":"Sanofi (India)","ror":"https://ror.org/043zsj038","country_code":"IN","type":"company","lineage":["https://openalex.org/I3018075036","https://openalex.org/I4210138224"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Saravanan D","raw_affiliation_strings":["Global Development Centre, Sanofi-Synthelabo (India) Pvt. Ltd, Goa, India"],"raw_orcid":"https://orcid.org/0000-0003-0725-6079","affiliations":[{"raw_affiliation_string":"Global Development Centre, Sanofi-Synthelabo (India) Pvt. Ltd, Goa, India","institution_ids":["https://openalex.org/I4210138224"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011023477","display_name":"Prakash Muthudoss","orcid":"https://orcid.org/0000-0003-2136-3903","observed_orcids":["https://orcid.org/0000-0003-2136-3903"]},"institutions":[{"id":"https://openalex.org/I4210138224","display_name":"Sanofi (India)","ror":"https://ror.org/043zsj038","country_code":"IN","type":"company","lineage":["https://openalex.org/I3018075036","https://openalex.org/I4210138224"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Prakash Muthudoss","raw_affiliation_strings":["Global Development Centre, Sanofi-Synthelabo (India) Pvt. Ltd, Goa, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Global Development Centre, Sanofi-Synthelabo (India) Pvt. Ltd, Goa, India","institution_ids":["https://openalex.org/I4210138224"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002951307","display_name":"Praveen Khullar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138224","display_name":"Sanofi (India)","ror":"https://ror.org/043zsj038","country_code":"IN","type":"company","lineage":["https://openalex.org/I3018075036","https://openalex.org/I4210138224"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Praveen Khullar","raw_affiliation_strings":["Global Development Centre, Sanofi-Synthelabo (India) Pvt. Ltd, Goa, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Global Development Centre, Sanofi-Synthelabo (India) Pvt. Ltd, Goa, India","institution_ids":["https://openalex.org/I4210138224"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112876437","display_name":"A. Rose Venis","orcid":"https://orcid.org/0000-0002-0699-1648","observed_orcids":["https://orcid.org/0000-0002-0699-1648"]},"institutions":[{"id":"https://openalex.org/I4405272038","display_name":"St. Joseph's College","ror":"https://ror.org/03feb5668","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405272038"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rose Venis A","raw_affiliation_strings":["Department of Chemistry, St. Joseph\u2019s College, Trichirappalli, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, St. Joseph\u2019s College, Trichirappalli, India","institution_ids":["https://openalex.org/I4405272038"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101574451"],"corresponding_institution_ids":["https://openalex.org/I4210138224"],"apc_list":{"value":3260,"currency":"USD","value_usd":3260},"apc_paid":null,"fwci":1.1742,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.69790532,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"16","issue":"1","first_page":"136","last_page":"151"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11881","display_name":"Crystallization and Solubility Studies","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10615","display_name":"Granular flow and fluidized beds","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/agglomeration","display_name":"agglomeration","score":0.8420000076293945},{"id":"https://openalex.org/keywords/active-pharmaceutical-ingredients","display_name":"active pharmaceutical ingredients","score":0.6570000052452087},{"id":"https://openalex.org/keywords/dissolution","display_name":"dissolution","score":0.7110000252723694},{"id":"https://openalex.org/keywords/permeation","display_name":"permeation","score":0.781000018119812},{"id":"https://openalex.org/keywords/agglomerate-strength","display_name":"agglomerate strength","score":0.8119999766349792},{"id":"https://openalex.org/keywords/surface-energy","display_name":"surface energy","score":0.8519999980926514},{"id":"https://openalex.org/keywords/needle-shaped-particles","display_name":"needle-shaped particles","score":0.5199999809265137},{"id":"https://openalex.org/keywords/solid-state-characterization","display_name":"solid-state characterization","score":0.5600000023841858},{"id":"https://openalex.org/keywords/raw-material-variability","display_name":"raw material variability","score":0.6809999942779541},{"id":"https://openalex.org/keywords/biopharmaceutical-development","display_name":"biopharmaceutical development","score":0.5740000009536743}],"concepts":[{"id":"https://openalex.org/C86178769","wikidata":"https://www.wikidata.org/wiki/Q1130789","display_name":"Micronization","level":3,"score":0.9407992362976074},{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.7354227304458618},{"id":"https://openalex.org/C131850264","wikidata":"https://www.wikidata.org/wiki/Q383056","display_name":"Economies of agglomeration","level":2,"score":0.6031445264816284},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5668954253196716},{"id":"https://openalex.org/C45904493","wikidata":"https://www.wikidata.org/wiki/Q912807","display_name":"Active ingredient","level":2,"score":0.5572168827056885},{"id":"https://openalex.org/C39519442","wikidata":"https://www.wikidata.org/wiki/Q904893","display_name":"Differential scanning calorimetry","level":2,"score":0.5561729073524475},{"id":"https://openalex.org/C187530423","wikidata":"https://www.wikidata.org/wiki/Q7140503","display_name":"Particle size","level":2,"score":0.4790950119495392},{"id":"https://openalex.org/C62129180","wikidata":"https://www.wikidata.org/wiki/Q903984","display_name":"Ostwald ripening","level":2,"score":0.45143067836761475},{"id":"https://openalex.org/C206139338","wikidata":"https://www.wikidata.org/wiki/Q192355","display_name":"Raw material","level":2,"score":0.4504028260707855},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.44167396426200867},{"id":"https://openalex.org/C21880701","wikidata":"https://www.wikidata.org/wiki/Q2144042","display_name":"Process engineering","level":1,"score":0.4304819107055664},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.411374568939209},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.32373160123825073},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27211374044418335},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1103278398513794},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s12247-019-09424-1","doi":"https://doi.org/10.1007/s12247-019-09424-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12247-019-09424-1","pdf_url":null,"source":{"id":"https://openalex.org/S168111969","display_name":"Journal of Pharmaceutical Innovation","issn_l":"1872-5120","issn":["1872-5120","1939-8042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Innovation","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W571241385","https://openalex.org/W1542734677","https://openalex.org/W1545477383","https://openalex.org/W1589011741","https://openalex.org/W1969768793","https://openalex.org/W1974149149","https://openalex.org/W1975140804","https://openalex.org/W1980538211","https://openalex.org/W1992261074","https://openalex.org/W1996636629","https://openalex.org/W2002257481","https://openalex.org/W2002562802","https://openalex.org/W2003291502","https://openalex.org/W2021700672","https://openalex.org/W2027594430","https://openalex.org/W2029916609","https://openalex.org/W2037803874","https://openalex.org/W2043658704","https://openalex.org/W2057302806","https://openalex.org/W2061263372","https://openalex.org/W2061952624","https://openalex.org/W2066638801","https://openalex.org/W2073897423","https://openalex.org/W2079552263","https://openalex.org/W2079632937","https://openalex.org/W2081029053","https://openalex.org/W2081513817","https://openalex.org/W2084153391","https://openalex.org/W2111854935","https://openalex.org/W2135130257","https://openalex.org/W2164023377","https://openalex.org/W2267003277","https://openalex.org/W2330116297","https://openalex.org/W2337498673","https://openalex.org/W2560284613","https://openalex.org/W2594867839","https://openalex.org/W2606662197","https://openalex.org/W2761052490","https://openalex.org/W2897177456","https://openalex.org/W2900178925","https://openalex.org/W2947502230","https://openalex.org/W4238288166","https://openalex.org/W4239750817"],"related_works":["https://openalex.org/W2267003277","https://openalex.org/W4408422851","https://openalex.org/W2000389189","https://openalex.org/W4282836829","https://openalex.org/W2607321599","https://openalex.org/W7127346804","https://openalex.org/W2139852678","https://openalex.org/W1988673523","https://openalex.org/W1025784947","https://openalex.org/W4296104618"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-01-30T00:00:00"}