{"id":"https://openalex.org/W3000896595","doi":"https://doi.org/10.1016/j.ijbiomac.2020.01.209","title":"Hypoglycaemic effect and mechanism of an RG-II type polysaccharide purified from Aconitum coreanum in diet-induced obese mice","display_name":"Hypoglycaemic effect and mechanism of an RG-II type polysaccharide purified from Aconitum coreanum in diet-induced obese mice","publication_year":2020,"publication_date":"2020-01-22","ids":{"openalex":"https://openalex.org/W3000896595","doi":"https://doi.org/10.1016/j.ijbiomac.2020.01.209","mag":"3000896595","pmid":"https://pubmed.ncbi.nlm.nih.gov/31981662"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijbiomac.2020.01.209","doi":"https://doi.org/10.1016/j.ijbiomac.2020.01.209","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2020.01.209","pdf_url":null,"source":{"id":"https://openalex.org/S83853393","display_name":"International Journal of Biological Macromolecules","issn_l":"0141-8130","issn":["0141-8130","1879-0003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biological Macromolecules","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051898388","display_name":"Juan Su","orcid":"https://orcid.org/0000-0001-6239-1711","observed_orcids":["https://orcid.org/0000-0001-6239-1711"]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Juan Su","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101615074","display_name":"Xinya Liu","orcid":"https://orcid.org/0009-0007-7987-9714","observed_orcids":["https://orcid.org/0009-0007-7987-9714"]},"institutions":[{"id":"https://openalex.org/I53411278","display_name":"Chengdu University of Traditional Chinese Medicine","ror":"https://ror.org/00pcrz470","country_code":"CN","type":"education","lineage":["https://openalex.org/I53411278"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinya Liu","raw_affiliation_strings":["Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province 611130, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province 611130, China","institution_ids":["https://openalex.org/I53411278"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hanqing Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hanqing Li","raw_affiliation_strings":["Teaching Experimental Center, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Teaching Experimental Center, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100684404","display_name":"Xiang Cheng","orcid":"https://orcid.org/0000-0001-9019-7246","observed_orcids":["https://orcid.org/0000-0001-9019-7246","https://orcid.org/0009-0001-8278-3533","https://orcid.org/0009-0002-0756-1460"]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiang Cheng","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071899597","display_name":"Songshan Shi","orcid":"https://orcid.org/0000-0002-4693-4154","observed_orcids":["https://orcid.org/0000-0002-4693-4154"]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Songshan Shi","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100369056","display_name":"Ning Li","orcid":"https://orcid.org/0000-0002-8388-5080","observed_orcids":["https://orcid.org/0000-0002-8388-5080"]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ning Li","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jianjun Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianjun Wu","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101103851","display_name":"Yongbin Xu","orcid":"https://orcid.org/0000-0003-2347-8114","observed_orcids":["https://orcid.org/0000-0003-2347-8114"]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongbin Xu","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ruimin Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruimin Liu","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108835527","display_name":"Xueli Tian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueli Tian","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100416395","display_name":"Huijun Wang","orcid":"https://orcid.org/0000-0001-6319-498X","observed_orcids":["https://orcid.org/0000-0001-6319-498X"]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Huijun Wang","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China. Electronic address: huijun.wang@outlook.com","The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China. Electronic address: huijun.wang@outlook.com","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]},{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003682282","display_name":"Shunchun Wang","orcid":"https://orcid.org/0000-0003-0384-1350","observed_orcids":["https://orcid.org/0000-0003-0384-1350"]},"institutions":[{"id":"https://openalex.org/I2799435774","display_name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","ror":"https://ror.org/003cpqh10","country_code":"CN","type":"government","lineage":["https://openalex.org/I271893122","https://openalex.org/I2799435774","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shunchun Wang","raw_affiliation_strings":["The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China. Electronic address: shunchunwang@126.com","The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China. Electronic address: shunchunwang@126.com","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]},{"raw_affiliation_string":"The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, PR China","institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5003682282","https://openalex.org/A5100416395"],"corresponding_institution_ids":["https://openalex.org/I2799435774","https://openalex.org/I4210098460"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":2.9711,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.91887937,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"149","issue":null,"first_page":"359","last_page":"370"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.02810000069439411,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13095","display_name":"Plant-based Medicinal Research","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aconitum-coreanum","display_name":"Aconitum coreanum","score":0.9919999837875366},{"id":"https://openalex.org/keywords/hypoglycemic-effect","display_name":"hypoglycemic effect","score":0.9760000109672546},{"id":"https://openalex.org/keywords/diet-induced-obesity","display_name":"diet-induced obesity","score":0.8399999737739563},{"id":"https://openalex.org/keywords/insulin-sensitivity","display_name":"insulin sensitivity","score":0.5960000157356262},{"id":"https://openalex.org/keywords/glucose-tolerance","display_name":"glucose tolerance","score":0.968999981880188},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.5899999737739563},{"id":"https://openalex.org/keywords/m1-macrophages","display_name":"M1 macrophages","score":0.8709999918937683},{"id":"https://openalex.org/keywords/adipose-tissue","display_name":"adipose tissue","score":0.9580000042915344},{"id":"https://openalex.org/keywords/irs-1-serine-phosphorylation","display_name":"IRS-1 serine phosphorylation","score":0.8880000114440918},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.9380000233650208},{"id":"https://openalex.org/keywords/pi3k-akt-signaling","display_name":"PI3K/Akt signaling","score":0.9760000109672546},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9210000038146973}],"concepts":[{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6159619092941284},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.6145579814910889},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.6063910126686096},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5677100419998169},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5637783408164978},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5322432518005371},{"id":"https://openalex.org/C17093226","wikidata":"https://www.wikidata.org/wiki/Q2734081","display_name":"Carbohydrate metabolism","level":2,"score":0.4907320737838745},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.48714563250541687},{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.48320186138153076},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4272086024284363},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.4271122217178345},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.3137258291244507},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3094971776008606},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.270107626914978},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2609189748764038},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.23628553748130798}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008820","descriptor_name":"Mice, Obese","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019869","descriptor_name":"Phosphatidylinositol 3-Kinases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D031841","descriptor_name":"Aconitum","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051057","descriptor_name":"Proto-Oncogene Proteins c-akt","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ijbiomac.2020.01.209","doi":"https://doi.org/10.1016/j.ijbiomac.2020.01.209","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2020.01.209","pdf_url":null,"source":{"id":"https://openalex.org/S83853393","display_name":"International Journal of Biological Macromolecules","issn_l":"0141-8130","issn":["0141-8130","1879-0003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biological Macromolecules","raw_type":"journal-article"},{"id":"pmid:31981662","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31981662","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of biological macromolecules","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4492821138","display_name":null,"funder_award_id":"2019ZX09735001-004","funder_id":"https://openalex.org/F4320336020","funder_display_name":"National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology"},{"id":"https://openalex.org/G8371744003","display_name":null,"funder_award_id":"2019LK082","funder_id":"https://openalex.org/F4320326704","funder_display_name":"Shanghai University of Traditional Chinese Medicine"}],"funders":[{"id":"https://openalex.org/F4320321540","display_name":"Ministry of Science and Technology of the People's Republic of China","ror":"https://ror.org/027s68j25"},{"id":"https://openalex.org/F4320326704","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27"},{"id":"https://openalex.org/F4320336020","display_name":"National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1505106993","https://openalex.org/W1534360145","https://openalex.org/W1546304862","https://openalex.org/W1764140709","https://openalex.org/W1966336914","https://openalex.org/W1979709754","https://openalex.org/W1979731514","https://openalex.org/W2008869160","https://openalex.org/W2011210301","https://openalex.org/W2026514466","https://openalex.org/W2026927520","https://openalex.org/W2031637294","https://openalex.org/W2031980199","https://openalex.org/W2036852488","https://openalex.org/W2038018821","https://openalex.org/W2040966742","https://openalex.org/W2048473455","https://openalex.org/W2048669697","https://openalex.org/W2051182630","https://openalex.org/W2054415546","https://openalex.org/W2063131576","https://openalex.org/W2073882423","https://openalex.org/W2101328621","https://openalex.org/W2108416978","https://openalex.org/W2108462699","https://openalex.org/W2125058279","https://openalex.org/W2129316761","https://openalex.org/W2136024338","https://openalex.org/W2143055774","https://openalex.org/W2150367899","https://openalex.org/W2152037832","https://openalex.org/W2160234571","https://openalex.org/W2589953033","https://openalex.org/W2615885639","https://openalex.org/W2623737995","https://openalex.org/W2731349674","https://openalex.org/W2777196297","https://openalex.org/W2810405081","https://openalex.org/W2925793776","https://openalex.org/W2963958001","https://openalex.org/W2988299614"],"related_works":["https://openalex.org/W7164138503","https://openalex.org/W1973427978","https://openalex.org/W3088885766","https://openalex.org/W4414306792","https://openalex.org/W7128393631","https://openalex.org/W2763518393","https://openalex.org/W2956258460","https://openalex.org/W4319748024","https://openalex.org/W2095863111","https://openalex.org/W4306169089"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-01-30T00:00:00"}