{"id":"https://openalex.org/W3000659157","doi":"https://doi.org/10.1016/s0923-7534(20)30181-2","title":"P-0252 Braf Mutation, Use of Bevacizumab and Survival of Colorectal Cancer","display_name":"P-0252 Braf Mutation, Use of Bevacizumab and Survival of Colorectal Cancer","publication_year":2012,"publication_date":"2012-06-01","ids":{"openalex":"https://openalex.org/W3000659157","doi":"https://doi.org/10.1016/s0923-7534(20)30181-2","mag":"3000659157"},"language":"en","primary_location":{"id":"doi:10.1016/s0923-7534(20)30181-2","doi":"https://doi.org/10.1016/s0923-7534(20)30181-2","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0923-7534(20)30181-2","pdf_url":"https://doi.org/10.1016/s0923-7534(20)30181-2","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s0923-7534(20)30181-2","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112070178","display_name":"Katerina Shulman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4210113769","display_name":"Carmel Medical Center","ror":"https://ror.org/02cy9a842","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113769"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Katerina Shulman","raw_affiliation_strings":["CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology and Rambam Medical Center, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology and Rambam Medical Center, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I4210113769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005524023","display_name":"Ofra Barnett\u2010Griness","orcid":"https://orcid.org/0009-0004-0563-9230","observed_orcids":["https://orcid.org/0009-0004-0563-9230"]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4210113769","display_name":"Carmel Medical Center","ror":"https://ror.org/02cy9a842","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113769"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Ofra Barnett-Griness","raw_affiliation_strings":["CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I4210113769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087944878","display_name":"Meira Frank","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4210113769","display_name":"Carmel Medical Center","ror":"https://ror.org/02cy9a842","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113769"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Meira Frank","raw_affiliation_strings":["CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I4210113769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027915642","display_name":"Abraham Kuten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801301638","display_name":"Rambam Health Care Campus","ror":"https://ror.org/01fm87m50","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801301638"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Abraham Kuten","raw_affiliation_strings":["Rambam Medical Center, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rambam Medical Center, Haifa","institution_ids":["https://openalex.org/I2801301638"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070703103","display_name":"Stephen B. Gruber","orcid":"https://orcid.org/0000-0001-8656-7822","observed_orcids":["https://orcid.org/0000-0001-8656-7822"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210117038","display_name":"USC Norris Comprehensive Cancer Center","ror":"https://ror.org/01nmyfr60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800154431","https://openalex.org/I4210117038"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen B. Gruber","raw_affiliation_strings":["Norris Cancer Center University of Southern California, LA, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Norris Cancer Center University of Southern California, LA, CA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210117038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034362238","display_name":"Flavio Lejbkowicz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4210113769","display_name":"Carmel Medical Center","ror":"https://ror.org/02cy9a842","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113769"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Flavio Lejbkowicz","raw_affiliation_strings":["CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I4210113769"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082547550","display_name":"Gad Rennert","orcid":"https://orcid.org/0000-0002-8512-068X","observed_orcids":["https://orcid.org/0000-0002-8512-068X"]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4210113769","display_name":"Carmel Medical Center","ror":"https://ror.org/02cy9a842","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113769"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Gad Rennert","raw_affiliation_strings":["CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHS National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I4210113769"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"23","issue":null,"first_page":"iv102","last_page":"iv102"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/braf-mutation","display_name":"BRAF mutation","score":0.828000009059906},{"id":"https://openalex.org/keywords/kras-mutation","display_name":"KRAS mutation","score":0.9879999756813049},{"id":"https://openalex.org/keywords/bevacizumab","display_name":"bevacizumab","score":0.972000002861023},{"id":"https://openalex.org/keywords/metastatic-colorectal-cancer","display_name":"metastatic colorectal cancer","score":0.9710000157356262},{"id":"https://openalex.org/keywords/first-line-chemotherapy","display_name":"first-line chemotherapy","score":0.7910000085830688},{"id":"https://openalex.org/keywords/oxaliplatin","display_name":"oxaliplatin","score":0.7910000085830688},{"id":"https://openalex.org/keywords/irinotecan","display_name":"irinotecan","score":0.9990000128746033},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.703000009059906},{"id":"https://openalex.org/keywords/anti-vegf-monoclonal-antibody","display_name":"anti-VEGF monoclonal antibody","score":0.8500000238418579},{"id":"https://openalex.org/keywords/anti-egfr-monoclonal-antibody","display_name":"anti-EGFR monoclonal antibody","score":0.9309999942779541},{"id":"https://openalex.org/keywords/cetuximab","display_name":"cetuximab","score":0.8090000152587891},{"id":"https://openalex.org/keywords/panitumumab","display_name":"panitumumab","score":0.9990000128746033},{"id":"https://openalex.org/keywords/predictive-biomarkers","display_name":"predictive biomarkers","score":0.7200000286102295},{"id":"https://openalex.org/keywords/treatment-response-prediction","display_name":"treatment response prediction","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9683127999305725},{"id":"https://openalex.org/C2777802072","wikidata":"https://www.wikidata.org/wiki/Q413299","display_name":"Bevacizumab","level":3,"score":0.8498682975769043},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.7310274839401245},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5747125148773193},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43062639236450195},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.41813623905181885},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.329324334859848},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.31059250235557556},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.11857309937477112},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10654780268669128},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09670904278755188},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0923-7534(20)30181-2","doi":"https://doi.org/10.1016/s0923-7534(20)30181-2","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0923-7534(20)30181-2","pdf_url":"https://doi.org/10.1016/s0923-7534(20)30181-2","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/s0923-7534(20)30181-2","doi":"https://doi.org/10.1016/s0923-7534(20)30181-2","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0923-7534(20)30181-2","pdf_url":"https://doi.org/10.1016/s0923-7534(20)30181-2","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2999282187","https://openalex.org/W3090356530","https://openalex.org/W2569551489","https://openalex.org/W2999247162","https://openalex.org/W2288746866","https://openalex.org/W2132598198","https://openalex.org/W2127640925","https://openalex.org/W2890258973","https://openalex.org/W2054122365","https://openalex.org/W2322917643"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-09-21T07:43:02.447757","created_date":"2020-01-23T00:00:00"}
