{"id":"https://openalex.org/W3000654447","doi":"https://doi.org/10.1007/s00125-019-05059-6","title":"Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes","display_name":"Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes","publication_year":2020,"publication_date":"2020-01-08","ids":{"openalex":"https://openalex.org/W3000654447","doi":"https://doi.org/10.1007/s00125-019-05059-6","mag":"3000654447","pmid":"https://pubmed.ncbi.nlm.nih.gov/31915891","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7002226"},"language":"en","primary_location":{"id":"doi:10.1007/s00125-019-05059-6","doi":"https://doi.org/10.1007/s00125-019-05059-6","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00125-019-05059-6","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00125-019-05059-6.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00125-019-05059-6.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001509106","display_name":"Ivy C. Mason","orcid":"https://orcid.org/0000-0003-4118-4275","observed_orcids":["https://orcid.org/0000-0003-4118-4275"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ivy C. Mason","raw_affiliation_strings":["Brigham and Women's Hospital, Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, 221 Longwood Avenue, Boston, MA, 02115, USA","Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0003-4118-4275","affiliations":[{"raw_affiliation_string":"Brigham and Women's Hospital, Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, 221 Longwood Avenue, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020367553","display_name":"Jingyi Qian","orcid":"https://orcid.org/0000-0002-8793-9330","observed_orcids":["https://orcid.org/0000-0002-8793-9330"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jingyi Qian","raw_affiliation_strings":["Brigham and Women's Hospital, Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, 221 Longwood Avenue, Boston, MA, 02115, USA","Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8793-9330","affiliations":[{"raw_affiliation_string":"Brigham and Women's Hospital, Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, 221 Longwood Avenue, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048806317","display_name":"Gail Kurr Adler","orcid":"https://orcid.org/0000-0003-3506-7347","observed_orcids":["https://orcid.org/0000-0003-3506-7347"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gail K. Adler","raw_affiliation_strings":["Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0003-3506-7347","affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022786999","display_name":"Frank A. J. L. Scheer","orcid":"https://orcid.org/0000-0002-2014-7582","observed_orcids":["https://orcid.org/0000-0002-2014-7582","https://orcid.org/0000-0002-6682-0103"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Frank A. J. L. Scheer","raw_affiliation_strings":["Brigham and Women's Hospital, Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, 221 Longwood Avenue, Boston, MA, 02115, USA. fscheer@bwh.harvard.edu","Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA. fscheer@bwh.harvard.edu","Brigham and Women's Hospital, Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, 221 Longwood Avenue, Boston, MA, 02115, USA","Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-2014-7582","affiliations":[{"raw_affiliation_string":"Brigham and Women's Hospital, Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, 221 Longwood Avenue, Boston, MA, 02115, USA. fscheer@bwh.harvard.edu","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA. fscheer@bwh.harvard.edu","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Brigham and Women's Hospital, Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, 221 Longwood Avenue, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5022786999"],"corresponding_institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":{"value":4480,"currency":"USD","value_usd":4480},"fwci":5.4247,"has_fulltext":true,"cited_by_count":378,"citation_normalized_percentile":{"value":0.99354839,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"63","issue":"3","first_page":"462","last_page":"472"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11373","display_name":"Sleep and Work-Related Fatigue","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12745","display_name":"Dietary Effects on Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circadian-rhythm-disruption","display_name":"circadian rhythm disruption","score":0.8460000157356262},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.9739999771118164},{"id":"https://openalex.org/keywords/glucose-metabolism","display_name":"glucose metabolism","score":0.9819999933242798},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9710000157356262},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.8949999809265137}],"concepts":[{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.94865483045578},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6065653562545776},{"id":"https://openalex.org/C17093226","wikidata":"https://www.wikidata.org/wiki/Q2734081","display_name":"Carbohydrate metabolism","level":2,"score":0.572580873966217},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.5625017881393433},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5256917476654053},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5034951567649841},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.47431254386901855},{"id":"https://openalex.org/C38606739","wikidata":"https://www.wikidata.org/wiki/Q5121352","display_name":"Circadian clock","level":3,"score":0.4460391700267792},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.44575831294059753},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.42468389868736267},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34316396713256836}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D021081","descriptor_name":"Chronobiology Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D021081","descriptor_name":"Chronobiology Disorders","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D021081","descriptor_name":"Chronobiology Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D050260","descriptor_name":"Carbohydrate Metabolism","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D050417","descriptor_name":"Insulin-Secreting Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00125-019-05059-6","doi":"https://doi.org/10.1007/s00125-019-05059-6","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00125-019-05059-6","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00125-019-05059-6.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},{"id":"pmid:31915891","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31915891","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7002226","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7002226","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Diabetologia","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s00125-019-05059-6","doi":"https://doi.org/10.1007/s00125-019-05059-6","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00125-019-05059-6","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00125-019-05059-6.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[{"id":"https://openalex.org/G174333297","display_name":"Meal Time Effects on Metabolic Health.","funder_award_id":"R01DK099512","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2272231056","display_name":"Role of Meal Timing in Efficacy of Bariatric Surgery in Obese Individuals","funder_award_id":"R01HL140574","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2856400587","display_name":"Impact of Malatonin, Food Timing and Receptor Variant on Type 2 Diabetes Risk","funder_award_id":"R01DK105072","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2982121942","display_name":"The Harvard Clinical and Translational Science Center","funder_award_id":"UL1TR002541","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4094572490","display_name":"Development of countermeasures against adverse metabolic effects of shift work","funder_award_id":"R01HL118601","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5140157915","display_name":"Training Program in Hypertension","funder_award_id":"T32HL007609","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5362432454","display_name":"Melatonin and Receptor Gene Variant: Linking Circadian System and Type 2 Diabetes","funder_award_id":"R01DK102696","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8953346930","display_name":"Aldosterone and Cardiovascular Disease:  Research and Mentoring Program","funder_award_id":"K24HL103845","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000913420","display_name":"Training in Sleep, Circadian, and Respiratory Neurobiology","funder_award_id":"T32HL007901","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3000654447.pdf","grobid_xml":"https://content.openalex.org/works/W3000654447.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1511275384","https://openalex.org/W1973259490","https://openalex.org/W1997915932","https://openalex.org/W2027098051","https://openalex.org/W2054465353","https://openalex.org/W2056229820","https://openalex.org/W2069763186","https://openalex.org/W2072416063","https://openalex.org/W2077495163","https://openalex.org/W2081139788","https://openalex.org/W2082407123","https://openalex.org/W2091912666","https://openalex.org/W2100675645","https://openalex.org/W2107496653","https://openalex.org/W2113136381","https://openalex.org/W2114382885","https://openalex.org/W2116417140","https://openalex.org/W2122738447","https://openalex.org/W2126776706","https://openalex.org/W2127903745","https://openalex.org/W2129670950","https://openalex.org/W2130259798","https://openalex.org/W2138487775","https://openalex.org/W2139826323","https://openalex.org/W2156331475","https://openalex.org/W2159185691","https://openalex.org/W2162026342","https://openalex.org/W2162691926","https://openalex.org/W2164824098","https://openalex.org/W2166166135","https://openalex.org/W2166609167","https://openalex.org/W2237552187","https://openalex.org/W2332254719","https://openalex.org/W2605902884","https://openalex.org/W2611680186","https://openalex.org/W2617460679","https://openalex.org/W2703663510","https://openalex.org/W2789915134","https://openalex.org/W2791011305","https://openalex.org/W2792167022","https://openalex.org/W2795064071","https://openalex.org/W2799787925","https://openalex.org/W2807200695","https://openalex.org/W2840330380","https://openalex.org/W2901849928","https://openalex.org/W2914619838","https://openalex.org/W2943037971","https://openalex.org/W2949668662","https://openalex.org/W2963628232","https://openalex.org/W2997273097","https://openalex.org/W4233878194"],"related_works":["https://openalex.org/W2332254719","https://openalex.org/W4224317904","https://openalex.org/W4413358525","https://openalex.org/W7166122417","https://openalex.org/W4415031626","https://openalex.org/W7164808302","https://openalex.org/W4401374281","https://openalex.org/W4320728105","https://openalex.org/W2593643084","https://openalex.org/W7138938550"],"abstract_inverted_index":{"The":[0,20],"circadian":[1,33,36,59,81,84,93,104,123,132],"system":[2,60],"generates":[3],"endogenous":[4],"rhythms":[5,43,82],"of":[6,12,22,57,92,95,103,118,131],"approximately":[7],"24":[8],"h,":[9],"the":[10,32,55,58,101,114,126,129],"synchronisation":[11],"which":[13],"are":[14,29],"vital":[15],"for":[16],"healthy":[17,68],"bodily":[18],"function.":[19],"timing":[21],"many":[23],"physiological":[24],"processes,":[25],"including":[26],"glucose":[27,65,96,107,135],"metabolism,":[28],"coordinated":[30],"by":[31,79],"system,":[34],"and":[35,61,70,83,86,109,122],"disruptions":[37,105],"that":[38],"desynchronise":[39],"or":[40],"misalign":[41],"these":[42],"can":[44],"result":[45],"in":[46,64,67,139],"adverse":[47],"health":[48],"outcomes.":[49],"In":[50],"this":[51],"review,":[52],"we":[53,88],"cover":[54],"role":[56],"its":[62],"disruption":[63,85,133],"metabolism":[66,136],"individuals":[69,71],"with":[72],"type":[73,110,119],"2":[74,111,120],"diabetes":[75,121],"mellitus.":[76],"We":[77,98],"begin":[78],"defining":[80],"then":[87],"provide":[89],"an":[90],"overview":[91],"regulation":[94],"metabolism.":[97],"next":[99],"discuss":[100],"impact":[102,130],"on":[106,134],"control":[108],"diabetes.":[112],"Given":[113],"concurrent":[115],"high":[116],"prevalence":[117],"disruption,":[124],"understanding":[125],"mechanisms":[127],"underlying":[128],"may":[137],"aid":[138],"improving":[140],"glycaemic":[141],"control.":[142]},"counts_by_year":[{"year":2026,"cited_by_count":58},{"year":2025,"cited_by_count":75},{"year":2024,"cited_by_count":78},{"year":2023,"cited_by_count":62},{"year":2022,"cited_by_count":51},{"year":2021,"cited_by_count":36},{"year":2020,"cited_by_count":17},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-01-23T00:00:00"}