{"id":"https://openalex.org/W3000543341","doi":"https://doi.org/10.15252/embr.201947832","title":"NAD(P) transhydrogenase has vital non\u2010mitochondrial functions in malaria parasite transmission","display_name":"NAD(P) transhydrogenase has vital non\u2010mitochondrial functions in malaria parasite transmission","publication_year":2020,"publication_date":"2020-01-17","ids":{"openalex":"https://openalex.org/W3000543341","doi":"https://doi.org/10.15252/embr.201947832","mag":"3000543341","pmid":"https://pubmed.ncbi.nlm.nih.gov/31951090","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7054674"},"language":"en","primary_location":{"id":"doi:10.15252/embr.201947832","doi":"https://doi.org/10.15252/embr.201947832","is_oa":true,"landing_page_url":"https://doi.org/10.15252/embr.201947832","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embr.201947832","source":{"id":"https://openalex.org/S57252141","display_name":"EMBO Reports","issn_l":"1469-221X","issn":["1469-221X","1469-3178"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embr.201947832","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101691713","display_name":"Sadia Saeed","orcid":"https://orcid.org/0000-0001-6737-4152","observed_orcids":["https://orcid.org/0000-0001-6737-4152"]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sadia Saeed","raw_affiliation_strings":["Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK","Department of Infection Biology Faculty of Infectious and Tropical Diseases London School of Hygiene &amp; Tropical Medicine London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK","institution_ids":["https://openalex.org/I4210089966"]},{"raw_affiliation_string":"Department of Infection Biology Faculty of Infectious and Tropical Diseases London School of Hygiene &amp; Tropical Medicine London UK","institution_ids":["https://openalex.org/I4210089966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035527299","display_name":"Annie Z. Tremp","orcid":"https://orcid.org/0000-0003-4042-9074","observed_orcids":["https://orcid.org/0000-0003-4042-9074"]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Annie Z Tremp","raw_affiliation_strings":["Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK","Department of Infection Biology Faculty of Infectious and Tropical Diseases London School of Hygiene &amp; Tropical Medicine London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK","institution_ids":["https://openalex.org/I4210089966"]},{"raw_affiliation_string":"Department of Infection Biology Faculty of Infectious and Tropical Diseases London School of Hygiene &amp; Tropical Medicine London UK","institution_ids":["https://openalex.org/I4210089966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101990390","display_name":"Vikram Sharma","orcid":"https://orcid.org/0000-0002-3833-7763","observed_orcids":["https://orcid.org/0000-0002-3833-7763"]},"institutions":[{"id":"https://openalex.org/I897542642","display_name":"University of Plymouth","ror":"https://ror.org/008n7pv89","country_code":"GB","type":"education","lineage":["https://openalex.org/I897542642"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Vikram Sharma","raw_affiliation_strings":["School of Biomedical Sciences, University of Plymouth, Plymouth, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, University of Plymouth, Plymouth, UK","institution_ids":["https://openalex.org/I897542642"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090617671","display_name":"Edwin Lasonder","orcid":"https://orcid.org/0000-0003-2582-3444","observed_orcids":["https://orcid.org/0000-0003-2582-3444"]},"institutions":[{"id":"https://openalex.org/I897542642","display_name":"University of Plymouth","ror":"https://ror.org/008n7pv89","country_code":"GB","type":"education","lineage":["https://openalex.org/I897542642"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Edwin Lasonder","raw_affiliation_strings":["School of Biomedical Sciences, University of Plymouth, Plymouth, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, University of Plymouth, Plymouth, UK","institution_ids":["https://openalex.org/I897542642"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010123876","display_name":"Johannes T. Dessens","orcid":"https://orcid.org/0000-0002-2070-6073","observed_orcids":["https://orcid.org/0000-0002-2070-6073"]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Johannes T Dessens","raw_affiliation_strings":["Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK","Department of Infection Biology Faculty of Infectious and Tropical Diseases London School of Hygiene &amp; Tropical Medicine London UK"],"raw_orcid":"https://orcid.org/0000-0002-2070-6073","affiliations":[{"raw_affiliation_string":"Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK","institution_ids":["https://openalex.org/I4210089966"]},{"raw_affiliation_string":"Department of Infection Biology Faculty of Infectious and Tropical Diseases London School of Hygiene &amp; Tropical Medicine London UK","institution_ids":["https://openalex.org/I4210089966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5010123876"],"corresponding_institution_ids":["https://openalex.org/I4210089966"],"apc_list":{"value":5200,"currency":"USD","value_usd":5200},"apc_paid":{"value":5200,"currency":"USD","value_usd":5200},"fwci":1.8291,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.8575333,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":97},"biblio":{"volume":"21","issue":"3","first_page":"e47832","last_page":"e47832"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12178","display_name":"Bird parasitology and diseases","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasmodium","display_name":"Plasmodium","score":0.8320000171661377},{"id":"https://openalex.org/keywords/crystalloids","display_name":"crystalloids","score":0.7490000128746033},{"id":"https://openalex.org/keywords/sporozoite-development","display_name":"sporozoite development","score":0.9200000166893005},{"id":"https://openalex.org/keywords/sporogony","display_name":"sporogony","score":0.9290000200271606},{"id":"https://openalex.org/keywords/apicoplast","display_name":"apicoplast","score":0.8489999771118164},{"id":"https://openalex.org/keywords/nadph","display_name":"NADPH","score":0.7480000257492065},{"id":"https://openalex.org/keywords/organelle-biogenesis","display_name":"organelle biogenesis","score":0.7670000195503235}],"concepts":[{"id":"https://openalex.org/C185032368","wikidata":"https://www.wikidata.org/wiki/Q1365243","display_name":"Tropical medicine","level":2,"score":0.6884293556213379},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.5893881916999817},{"id":"https://openalex.org/C547646559","wikidata":"https://www.wikidata.org/wiki/Q162297","display_name":"Hygiene","level":2,"score":0.5707040429115295},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.43924060463905334},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33893561363220215},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.17225328087806702},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11837205290794373},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.10319164395332336}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009243","descriptor_name":"NAD","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009249","descriptor_name":"NADP","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009250","descriptor_name":"NADP Transhydrogenases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.15252/embr.201947832","doi":"https://doi.org/10.15252/embr.201947832","is_oa":true,"landing_page_url":"https://doi.org/10.15252/embr.201947832","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embr.201947832","source":{"id":"https://openalex.org/S57252141","display_name":"EMBO Reports","issn_l":"1469-221X","issn":["1469-221X","1469-3178"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7054674","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7054674","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO Rep","raw_type":"Text"},{"id":"pmid:31951090","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31951090","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO reports","raw_type":"Journal Article"},{"id":"pmh:oai:nrl.northumbria.ac.uk:42864","doi":null,"is_oa":false,"landing_page_url":"http://nrl.northumbria.ac.uk/id/eprint/42864/1/embr.201947832.pdf","pdf_url":"http://nrl.northumbria.ac.uk/id/eprint/42864/1/embr.201947832.pdf","source":{"id":"https://openalex.org/S4306401884","display_name":"Northumbria Research Link (Northumbria University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32394136","host_organization_name":"Northumbria University","host_organization_lineage":["https://openalex.org/I32394136"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:researchonline.lshtm.ac.uk:4655959","doi":null,"is_oa":false,"landing_page_url":"https://researchonline.lshtm.ac.uk/view/creators/ipmbssae.html>;","pdf_url":null,"source":{"id":"https://openalex.org/S4306402527","display_name":"LSHTM Research Online (London School of Hygiene and Tropical Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210089966","host_organization_name":"London School of Hygiene & Tropical Medicine","host_organization_lineage":["https://openalex.org/I4210089966"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:pearl.plymouth.ac.uk:bhs-research-1290","doi":null,"is_oa":true,"landing_page_url":"https://pearl.plymouth.ac.uk/bhs-research/291","pdf_url":"https://pearl.plymouth.ac.uk/context/bhs-research/article/1290/viewcontent/Saeed_et_al_2020_EMBO_reports.pdf","source":{"id":"https://openalex.org/S4306402507","display_name":"PEARL (University of Plymouth)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I897542642","host_organization_name":"University of Plymouth","host_organization_lineage":["https://openalex.org/I897542642"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"School of Biomedical Sciences","raw_type":"article"},{"id":"pmh:oai:pearl.plymouth.ac.uk:10026.1/15442","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10026.1/15442","pdf_url":null,"source":{"id":"https://openalex.org/S4306402507","display_name":"PEARL (University of Plymouth)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I897542642","host_organization_name":"University of Plymouth","host_organization_lineage":["https://openalex.org/I897542642"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.15252/embr.201947832","doi":"https://doi.org/10.15252/embr.201947832","is_oa":true,"landing_page_url":"https://doi.org/10.15252/embr.201947832","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embr.201947832","source":{"id":"https://openalex.org/S57252141","display_name":"EMBO Reports","issn_l":"1469-221X","issn":["1469-221X","1469-3178"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4389587184","display_name":null,"funder_award_id":"MR/P021611","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G4755038647","display_name":null,"funder_award_id":"MR/P021611","funder_id":"https://openalex.org/F4320338126","funder_display_name":"Medical Research Foundation"},{"id":"https://openalex.org/G4952477627","display_name":"Molecular mechanisms of sporogonic development in malaria parasites","funder_award_id":"MR/P021611/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5873253796","display_name":"LAP function in apicomplexan parasite development","funder_award_id":"BB/M001598/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G6120948164","display_name":null,"funder_award_id":"88449","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G6452573993","display_name":"Studying the molecular interactions of Plasmodium LCCL proteins to elucidate their roles in malaria transmission.","funder_award_id":"088449","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G8533233496","display_name":null,"funder_award_id":"BB/M001598","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G8992590666","display_name":null,"funder_award_id":"BB/M001598","funder_id":"https://openalex.org/F4320314731","funder_display_name":"UK Research and Innovation"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320314731","display_name":"UK Research and Innovation","ror":"https://ror.org/001aqnf71"},{"id":"https://openalex.org/F4320321637","display_name":"Department for International Development","ror":"https://ror.org/05rf29967"},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"},{"id":"https://openalex.org/F4320338126","display_name":"Medical Research Foundation","ror":"https://ror.org/05q2q3076"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3000543341.pdf","grobid_xml":"https://content.openalex.org/works/W3000543341.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W175072153","https://openalex.org/W1539603839","https://openalex.org/W1541322308","https://openalex.org/W1548805555","https://openalex.org/W1967129535","https://openalex.org/W1978337753","https://openalex.org/W1982189494","https://openalex.org/W1985207898","https://openalex.org/W1992233431","https://openalex.org/W1994494217","https://openalex.org/W2002900693","https://openalex.org/W2009359219","https://openalex.org/W2017570284","https://openalex.org/W2034357086","https://openalex.org/W2041128667","https://openalex.org/W2042072108","https://openalex.org/W2044663689","https://openalex.org/W2045033651","https://openalex.org/W2045581156","https://openalex.org/W2047687503","https://openalex.org/W2047798716","https://openalex.org/W2054607716","https://openalex.org/W2057062529","https://openalex.org/W2064987052","https://openalex.org/W2076845395","https://openalex.org/W2077387356","https://openalex.org/W2079893298","https://openalex.org/W2080412532","https://openalex.org/W2085960374","https://openalex.org/W2086476930","https://openalex.org/W2087986654","https://openalex.org/W2088366327","https://openalex.org/W2091585581","https://openalex.org/W2096747748","https://openalex.org/W2104454769","https://openalex.org/W2104754657","https://openalex.org/W2110343132","https://openalex.org/W2124561648","https://openalex.org/W2131960328","https://openalex.org/W2132673947","https://openalex.org/W2134213012","https://openalex.org/W2136193548","https://openalex.org/W2144876507","https://openalex.org/W2155002425","https://openalex.org/W2155673993","https://openalex.org/W2157201655","https://openalex.org/W2161018255","https://openalex.org/W2165234877","https://openalex.org/W2166180037","https://openalex.org/W2170097588","https://openalex.org/W2170805315","https://openalex.org/W2441346477","https://openalex.org/W2524071693","https://openalex.org/W2538215728","https://openalex.org/W2605835268","https://openalex.org/W2736273628","https://openalex.org/W2754309304","https://openalex.org/W2898336683"],"related_works":["https://openalex.org/W4206235638","https://openalex.org/W4382397239","https://openalex.org/W58207419","https://openalex.org/W2935729883","https://openalex.org/W2048871745","https://openalex.org/W2073436727","https://openalex.org/W2319289405","https://openalex.org/W137574759","https://openalex.org/W1997742864","https://openalex.org/W7054854078"],"abstract_inverted_index":{"Nicotinamide":[0],"adenine":[1],"dinucleotide":[2],"(NAD)":[3],"and":[4,17,27,39,51],"its":[5,102],"phosphorylated":[6],"form":[7,18],"(NADP)":[8],"are":[9],"vital":[10],"for":[11,82,107,141],"cell":[12],"function":[13,114],"in":[14,25,45,57,98,115,128],"all":[15],"organisms":[16],"cofactors":[19],"to":[20,76,87,117,156,162],"a":[21,70,121,136,157,164],"host":[22],"of":[23,49,55,120,131,139,159,167],"enzymes":[24],"catabolic":[26],"anabolic":[28],"processes.":[29],"NAD(P)":[30],"transhydrogenases":[31],"(NTHs)":[32],"catalyse":[33],"hydride":[34],"ion":[35],"transfer":[36],"between":[37],"NAD(H)":[38],"NADP(H).":[40],"Membrane-bound":[41],"NTH":[42,73,92,134,155],"isoforms":[43],"reside":[44],"the":[46,52,77,118,129],"cytoplasmic":[47],"membrane":[48,54],"bacteria,":[50],"inner":[53],"mitochondria":[56],"metazoans,":[58],"where":[59],"they":[60],"generate":[61],"NADPH.":[62],"Here,":[63],"we":[64],"show":[65],"that":[66,74,91,150],"malaria":[67],"parasites":[68],"encode":[69],"single":[71,122],"membrane-bound":[72],"localises":[75],"crystalloid,":[78],"an":[79,94,112],"organelle":[80,143],"required":[81,106],"sporozoite":[83,108],"transmission":[84],"from":[85],"mosquitos":[86],"vertebrates.":[88],"We":[89],"demonstrate":[90],"has":[93],"essential":[95,113],"structural":[96],"role":[97],"crystalloid":[99,123],"biogenesis,":[100],"whilst":[101],"enzymatic":[103],"activity":[104,119],"is":[105],"development.":[109],"This":[110],"pinpoints":[111],"sporogony":[116],"protein.":[124],"Its":[125],"additional":[126],"presence":[127],"apicoplast":[130],"sporozoites":[132],"identifies":[133],"as":[135],"likely":[137],"supplier":[138],"NADPH":[140,168],"this":[142],"during":[144],"liver":[145],"infection.":[146],"Our":[147],"findings":[148],"reveal":[149],"Plasmodium":[151],"species":[152],"have":[153],"co-opted":[154],"variety":[158],"non-mitochondrial":[160],"organelles":[161],"provide":[163],"critical":[165],"source":[166],"reducing":[169],"power.":[170]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-01-23T00:00:00"}
