{"id":"https://openalex.org/W3000506953","doi":"https://doi.org/10.1038/s41598-019-56846-5","title":"Rhodopsin and melanopsin coexist in mammalian sperm cells and activate different signaling pathways for thermotaxis","display_name":"Rhodopsin and melanopsin coexist in mammalian sperm cells and activate different signaling pathways for thermotaxis","publication_year":2020,"publication_date":"2020-01-10","ids":{"openalex":"https://openalex.org/W3000506953","doi":"https://doi.org/10.1038/s41598-019-56846-5","mag":"3000506953","pmid":"https://pubmed.ncbi.nlm.nih.gov/31924821"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-019-56846-5","doi":"https://doi.org/10.1038/s41598-019-56846-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-56846-5","pdf_url":"https://www.nature.com/articles/s41598-019-56846-5.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-019-56846-5.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046708486","display_name":"Debarun Roy","orcid":"https://orcid.org/0000-0003-3579-7497","observed_orcids":["https://orcid.org/0000-0003-3579-7497"]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Debarun Roy","raw_affiliation_strings":["Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086111584","display_name":"Kohava Levi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Kohava Levi","raw_affiliation_strings":["Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006411146","display_name":"Vladimir Kiss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Vladimir Kiss","raw_affiliation_strings":["Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053759464","display_name":"Reinat Nevo","orcid":"https://orcid.org/0009-0000-3327-4022","observed_orcids":["https://orcid.org/0009-0000-3327-4022"]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Reinat Nevo","raw_affiliation_strings":["Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063601237","display_name":"Michael Eisenbach","orcid":"https://orcid.org/0000-0001-9048-4720","observed_orcids":["https://orcid.org/0000-0001-9048-4720"]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Michael Eisenbach","raw_affiliation_strings":["Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel. m.eisenbach@weizmann.ac.il","Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel. m.eisenbach@weizmann.ac.il","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Department of Biomolecular Sciences, The Weizmann Institute of Science, 7610001, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5063601237"],"corresponding_institution_ids":["https://openalex.org/I53964585"],"apc_list":{"value":1870,"currency":"USD","value_usd":1870},"apc_paid":{"value":1870,"currency":"USD","value_usd":1870},"fwci":1.9387,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.8464378,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"10","issue":"1","first_page":"112","last_page":"112"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.5297999978065491,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.5297999978065491,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.2782999873161316,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.13459999859333038,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhodopsin","display_name":"rhodopsin","score":0.9850000143051147},{"id":"https://openalex.org/keywords/melanopsin","display_name":"melanopsin","score":1.0},{"id":"https://openalex.org/keywords/spermatozoa","display_name":"spermatozoa","score":0.47600001096725464},{"id":"https://openalex.org/keywords/thermosensation","display_name":"thermosensation","score":0.9039999842643738},{"id":"https://openalex.org/keywords/signaling-pathways","display_name":"signaling pathways","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C3449773","wikidata":"https://www.wikidata.org/wiki/Q92594","display_name":"Melanopsin","level":4,"score":0.9520744681358337},{"id":"https://openalex.org/C30028475","wikidata":"https://www.wikidata.org/wiki/Q24785022","display_name":"Opsin","level":4,"score":0.8975040912628174},{"id":"https://openalex.org/C202033177","wikidata":"https://www.wikidata.org/wiki/Q423107","display_name":"Rhodopsin","level":3,"score":0.8339835405349731},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7092205286026001},{"id":"https://openalex.org/C189780591","wikidata":"https://www.wikidata.org/wiki/Q7187882","display_name":"Photopigment","level":3,"score":0.6582971811294556},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6398355960845947},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.6236410140991211},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2976314425468445},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24562039971351624},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.2408140003681183},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.10963618755340576},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.058811187744140625}],"mesh":[{"descriptor_ui":"D000071442","descriptor_name":"Taxis Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071442","descriptor_name":"Taxis Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071442","descriptor_name":"Taxis Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000099210","descriptor_name":"Melanopsin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012243","descriptor_name":"Rhodopsin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012243","descriptor_name":"Rhodopsin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012243","descriptor_name":"Rhodopsin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017299","descriptor_name":"Rod Opsins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017299","descriptor_name":"Rod Opsins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017299","descriptor_name":"Rod Opsins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41598-019-56846-5","doi":"https://doi.org/10.1038/s41598-019-56846-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-56846-5","pdf_url":"https://www.nature.com/articles/s41598-019-56846-5.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmid:31924821","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31924821","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5915287","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6954197","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6954197","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6954197","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:80674540aa894f2aa6575636f759219a","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/80674540aa894f2aa6575636f759219a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-019-56846-5","doi":"https://doi.org/10.1038/s41598-019-56846-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-56846-5","pdf_url":"https://www.nature.com/articles/s41598-019-56846-5.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/14","score":0.46000000834465027,"display_name":"Life below water"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3000506953.pdf","grobid_xml":"https://content.openalex.org/works/W3000506953.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W30905091","https://openalex.org/W147729479","https://openalex.org/W1560106330","https://openalex.org/W1593659237","https://openalex.org/W1870327319","https://openalex.org/W1986119242","https://openalex.org/W1989825341","https://openalex.org/W1992618284","https://openalex.org/W1993697025","https://openalex.org/W1994649709","https://openalex.org/W2008780831","https://openalex.org/W2010527651","https://openalex.org/W2012321776","https://openalex.org/W2012501909","https://openalex.org/W2016093128","https://openalex.org/W2025138486","https://openalex.org/W2028827939","https://openalex.org/W2040080912","https://openalex.org/W2041981946","https://openalex.org/W2045184964","https://openalex.org/W2056728757","https://openalex.org/W2059614747","https://openalex.org/W2079178498","https://openalex.org/W2080372016","https://openalex.org/W2081024860","https://openalex.org/W2100047096","https://openalex.org/W2105505566","https://openalex.org/W2106549514","https://openalex.org/W2117226055","https://openalex.org/W2119052115","https://openalex.org/W2121570154","https://openalex.org/W2132822756","https://openalex.org/W2133459692","https://openalex.org/W2135166444","https://openalex.org/W2160119905","https://openalex.org/W2167815619","https://openalex.org/W2168965096","https://openalex.org/W2567768304","https://openalex.org/W2609402416","https://openalex.org/W2804134029","https://openalex.org/W4231983662","https://openalex.org/W4252894973"],"related_works":["https://openalex.org/W248689124","https://openalex.org/W2432289121","https://openalex.org/W2108534912","https://openalex.org/W2165755710","https://openalex.org/W2077962766","https://openalex.org/W2130524075","https://openalex.org/W3174454293","https://openalex.org/W2064083171","https://openalex.org/W1971524741","https://openalex.org/W2529764422"],"abstract_inverted_index":{"Recently,":[0],"various":[1],"opsin":[2,33,170],"types,":[3],"known":[4,55],"to":[5,12,22,37,63],"be":[6,13,23],"involved":[7,24],"in":[8,15,26,42,45,65,75,149,154,167,173],"vision,":[9,31,155,168],"were":[10,106],"demonstrated":[11,138],"present":[14],"human":[16],"and":[17,21,84,89,141,157],"mouse":[18,123],"sperm":[19,46,66,104,124,151,176],"cells":[20,47,105,116,125],"there":[25],"thermosensing":[27],"for":[28],"thermotaxis.":[29],"In":[30],"each":[32,69,143,159],"type":[34],"is":[35,48,52],"restricted":[36],"specific":[38,72,133],"cells.":[39,177],"The":[40],"situation":[41],"this":[43],"respect":[44],"not":[49,54,58,128],"known.":[50],"It":[51],"also":[53],"whether":[56],"or":[57],"both":[59,109,118,169],"signaling":[60,134,163],"pathways,":[61],"found":[62,99],"function":[64],"thermotaxis,":[67,152],"are":[68],"activated":[70],"by":[71,108],"opsins,":[73,97],"as":[74,86,153],"vision.":[76],"Here":[77],"we":[78,98,136],"addressed":[79],"these":[80,96],"questions.":[81],"Choosing":[82],"rhodopsin":[83,140,156],"melanopsin":[85,130,142,158],"test":[87],"cases":[88],"employing":[90,121],"immunocytochemical":[91],"analysis":[92],"with":[93,132],"antibodies":[94],"against":[95],"that":[100,112,126,139],"the":[101,115,174],"majority":[102],"of":[103,114],"stained":[107],"antibodies,":[110],"indicating":[111],"most":[113],"contained":[117],"opsins.":[119],"By":[120],"mutant":[122],"do":[127],"express":[129],"combined":[131],"inhibitors,":[135],"furthermore":[137],"activates":[144],"a":[145,161],"different":[146,162],"pathway.":[147],"Thus,":[148],"mammalian":[150],"triggers":[160],"pathway":[164],"but,":[165],"unlike":[166],"types":[171],"coexist":[172],"same":[175]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":3}],"updated_date":"2026-09-20T07:33:13.661266","created_date":"2025-10-10T00:00:00"}