{"id":"https://openalex.org/W2999861654","doi":"https://doi.org/10.1089/thy.2019.0392","title":"Characteristics of Patients with Graves' Disease Whose Thyroid Hormone Levels Increase After Substituting Potassium Iodide for Methimazole in the First Trimester of Pregnancy","display_name":"Characteristics of Patients with Graves' Disease Whose Thyroid Hormone Levels Increase After Substituting Potassium Iodide for Methimazole in the First Trimester of Pregnancy","publication_year":2020,"publication_date":"2020-01-13","ids":{"openalex":"https://openalex.org/W2999861654","doi":"https://doi.org/10.1089/thy.2019.0392","mag":"2999861654","pmid":"https://pubmed.ncbi.nlm.nih.gov/31928169"},"language":"en","primary_location":{"id":"doi:10.1089/thy.2019.0392","doi":"https://doi.org/10.1089/thy.2019.0392","is_oa":false,"landing_page_url":"https://doi.org/10.1089/thy.2019.0392","pdf_url":null,"source":{"id":"https://openalex.org/S27569427","display_name":"Thyroid","issn_l":"1050-7256","issn":["1050-7256","1557-9077"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thyroid","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010801196","display_name":"Ai Yoshihara","orcid":"https://orcid.org/0000-0003-1323-4722","observed_orcids":["https://orcid.org/0000-0003-1323-4722"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Ai Yoshihara","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076464766","display_name":"Jaeduk Yoshimura Noh","orcid":"https://orcid.org/0000-0001-7340-8603","observed_orcids":["https://orcid.org/0000-0001-7340-8603"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jaeduk Yoshimura Noh","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026043860","display_name":"Natsuko Watanabe","orcid":"https://orcid.org/0000-0003-2297-5004","observed_orcids":["https://orcid.org/0000-0003-2297-5004"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Natsuko Watanabe","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018324834","display_name":"Yo Kunii","orcid":"https://orcid.org/0009-0002-0458-7446","observed_orcids":["https://orcid.org/0009-0002-0458-7446"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yo Kunii","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101614879","display_name":"Miho Suzuki","orcid":"https://orcid.org/0000-0002-4009-5126","observed_orcids":["https://orcid.org/0000-0002-4009-5126"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Miho Suzuki","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111555140","display_name":"Masako Matsumoto","orcid":"https://orcid.org/0009-0000-7265-6787","observed_orcids":["https://orcid.org/0009-0000-7265-6787"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masako Matsumoto","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026419938","display_name":"Nami Suzuki","orcid":"https://orcid.org/0000-0003-2877-6647","observed_orcids":["https://orcid.org/0000-0003-2877-6647"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nami Suzuki","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088705543","display_name":"Marino Hiruma","orcid":"https://orcid.org/0000-0003-3804-7640","observed_orcids":["https://orcid.org/0000-0003-3804-7640"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Marino Hiruma","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054996828","display_name":"Mitsuha Morisaki","orcid":"https://orcid.org/0000-0001-9589-9140","observed_orcids":["https://orcid.org/0000-0001-9589-9140"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsuha Morisaki","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103495061","display_name":"Akiko Kawaguchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akiko Kawaguchi","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014603629","display_name":"Kiminori Sugino","orcid":"https://orcid.org/0000-0002-9692-9871","observed_orcids":["https://orcid.org/0000-0002-9692-9871"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiminori Sugino","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028206707","display_name":"Koichi Ito","orcid":"https://orcid.org/0000-0002-2042-405X","observed_orcids":["https://orcid.org/0000-0002-2042-405X"]},"institutions":[{"id":"https://openalex.org/I4210105488","display_name":"Ito Hospital","ror":"https://ror.org/01pc3rk31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210105488"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koichi Ito","raw_affiliation_strings":["Department of Internal Medicine, Ito Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Ito Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4210105488"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5010801196"],"corresponding_institution_ids":["https://openalex.org/I4210105488"],"apc_list":null,"apc_paid":null,"fwci":1.6506,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.831929,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"30","issue":"3","first_page":"451","last_page":"456"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11538","display_name":"Ophthalmology and Eye Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/graves-disease","display_name":"Graves' disease","score":0.9909999966621399},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.6759999990463257},{"id":"https://openalex.org/keywords/first-trimester","display_name":"first trimester","score":0.8899999856948853},{"id":"https://openalex.org/keywords/methimazole","display_name":"methimazole","score":0.8180000185966492},{"id":"https://openalex.org/keywords/potassium-iodide","display_name":"potassium iodide","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hyperthyroidism","display_name":"hyperthyroidism","score":0.7300000190734863},{"id":"https://openalex.org/keywords/thyrotoxicosis","display_name":"thyrotoxicosis","score":0.9010000228881836},{"id":"https://openalex.org/keywords/trab","display_name":"TRAb","score":0.8090000152587891},{"id":"https://openalex.org/keywords/thyroid-hormone-levels","display_name":"thyroid hormone levels","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8002458810806274},{"id":"https://openalex.org/C2778707442","wikidata":"https://www.wikidata.org/wiki/Q7831049","display_name":"Trab","level":4,"score":0.7420916557312012},{"id":"https://openalex.org/C2776652619","wikidata":"https://www.wikidata.org/wiki/Q16483","display_name":"Graves' disease","level":3,"score":0.7390965223312378},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.7036340236663818},{"id":"https://openalex.org/C2776417830","wikidata":"https://www.wikidata.org/wiki/Q419663","display_name":"Methimazole","level":3,"score":0.5984842777252197},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.5913153886795044},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5662602782249451},{"id":"https://openalex.org/C539932907","wikidata":"https://www.wikidata.org/wiki/Q1103","display_name":"Iodine","level":2,"score":0.5560700297355652},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.537597119808197},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4736802875995636},{"id":"https://openalex.org/C2776606491","wikidata":"https://www.wikidata.org/wiki/Q1365501","display_name":"Antithyroid agent","level":4,"score":0.4453655779361725},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.43972715735435486},{"id":"https://openalex.org/C3019714739","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"First trimester","level":4,"score":0.4273589253425598},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.26662349700927734},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.09147387742996216},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006111","descriptor_name":"Graves Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006111","descriptor_name":"Graves Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008713","descriptor_name":"Methimazole","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011193","descriptor_name":"Potassium Iodide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011261","descriptor_name":"Pregnancy Trimester, First","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013956","descriptor_name":"Antithyroid Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057915","descriptor_name":"Drug Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1089/thy.2019.0392","doi":"https://doi.org/10.1089/thy.2019.0392","is_oa":false,"landing_page_url":"https://doi.org/10.1089/thy.2019.0392","pdf_url":null,"source":{"id":"https://openalex.org/S27569427","display_name":"Thyroid","issn_l":"1050-7256","issn":["1050-7256","1557-9077"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thyroid","raw_type":"journal-article"},{"id":"pmid:31928169","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31928169","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thyroid : official journal of the American Thyroid Association","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1199524426","https://openalex.org/W1899098051","https://openalex.org/W1980218657","https://openalex.org/W2002518487","https://openalex.org/W2045480717","https://openalex.org/W2069010991","https://openalex.org/W2073885718","https://openalex.org/W2078098699","https://openalex.org/W2081484437","https://openalex.org/W2095169350","https://openalex.org/W2102423760","https://openalex.org/W2109290482","https://openalex.org/W2131413823","https://openalex.org/W2135911798","https://openalex.org/W2147913311","https://openalex.org/W2734505999","https://openalex.org/W4293861220"],"related_works":["https://openalex.org/W3012011963","https://openalex.org/W1899098051","https://openalex.org/W7116844125","https://openalex.org/W7131346019","https://openalex.org/W3152017807","https://openalex.org/W2045480717","https://openalex.org/W3162024232","https://openalex.org/W2154874109","https://openalex.org/W4402326460","https://openalex.org/W4283158418"],"abstract_inverted_index":{"Background:":[0],"The":[1],"clinical":[2],"course":[3],"of":[4,23,36,88,134,136,147,156,172,185,192,198,213,221],"Graves'":[5],"disease":[6],"(GD)":[7],"in":[8,29,207],"women":[9,53],"who":[10,56],"switched":[11,63],"from":[12,64,174,217],"methimazole":[13],"(MMI)":[14],"to":[15,66,69,129,176,235],"potassium":[16],"iodide":[17,68,222],"(KI)":[18],"during":[19,72,96],"the":[20,34,73,89,99,131,137,151,154,166,170,179,186,193,199,218],"first":[21,74],"trimester":[22,75],"pregnancy":[24],"has":[25],"never":[26],"been":[27,58],"reported":[28],"detail.":[30],"Objective:":[31],"To":[32],"investigate":[33],"characteristics":[35],"GD":[37,55,90,103,214],"patients":[38,104,139,215],"whose":[39],"thyroid":[40,187],"hormone":[41],"levels":[42],"increase":[43],"after":[44,229],"substituting":[45],"KI":[46,113,141,177],"for":[47],"MMI.":[48],"Patients:":[49],"Two":[50],"hundred":[51],"forty":[52],"with":[54,60,122,140,150],"had":[57],"treated":[59],"MMI":[61,65,148,175],"and":[62,80,98,115,143,223],"inorganic":[67],"control":[70,130],"hyperthyroidism":[71],"between":[76],"January":[77],"1,":[78],"2005,":[79],"March":[81],"31,":[82],"2018.":[83],"Results:":[84],"In":[85],"133":[86],"(55.4%)":[87],"patients,":[91],"medication":[92,107,234],"was":[93,127,158,178,195],"completely":[94],"tapered":[95],"pregnancy,":[97],"other":[100],"107":[101,138],"(44.6%)":[102],"were":[105,111,117],"taking":[106,112,118],"at":[108,153,169],"delivery:":[109],"57":[110],"alone":[114],"50":[116],"an":[119],"antithyroid":[120,219],"drug":[121],"or":[123],"without":[124],"KI.":[125,236],"It":[126,203],"difficult":[128],"maternal":[132],"thyrotoxicosis":[133],"22":[135],"alone,":[142],"a":[144,196,210,231],"higher":[145],"dose":[146,152],"compared":[149],"time":[155,171],"conception":[157],"required":[159],"(worsened":[160],"group).":[161],"Multivariate":[162],"analysis":[163],"revealed":[164],"that":[165,182,209,224],"TRAb":[167],"value":[168],"switch":[173],"only":[180],"factor":[181],"predicted":[183],"continuation":[184],"suppression":[188],"medication,":[189],"but":[190],"none":[191],"parameters":[194],"predictor":[197],"worsened":[200],"group.":[201],"Conclusions:":[202],"must":[204],"be":[205],"kept":[206],"mind":[208],"certain":[211],"proportion":[212],"escape":[216],"effect":[220],"careful":[225],"follow-up":[226],"is":[227],"necessary":[228],"switching":[230],"pregnant":[232],"patient's":[233]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-01-23T00:00:00"}