{"id":"https://openalex.org/W2999028350","doi":"https://doi.org/10.1002/admi.202070001","title":"Poly(methyl methacrylate): Covalent Functionalization of PMMA Surface with L\u20103,4\u2010Dihydroxyphenylalanine (L\u2010DOPA) to Enhance its Biocompatibility and Adhesion to Corneal Tissue (Adv. Mater. Interfaces 1/2020)","display_name":"Poly(methyl methacrylate): Covalent Functionalization of PMMA Surface with L\u20103,4\u2010Dihydroxyphenylalanine (L\u2010DOPA) to Enhance its Biocompatibility and Adhesion to Corneal Tissue (Adv. Mater. Interfaces 1/2020)","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W2999028350","doi":"https://doi.org/10.1002/admi.202070001","mag":"2999028350"},"language":"en","primary_location":{"id":"doi:10.1002/admi.202070001","doi":"https://doi.org/10.1002/admi.202070001","is_oa":false,"landing_page_url":"https://doi.org/10.1002/admi.202070001","pdf_url":null,"source":{"id":"https://openalex.org/S2764385675","display_name":"Advanced Materials Interfaces","issn_l":"2196-7350","issn":["2196-7350"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Materials Interfaces","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004723792","display_name":"Roholah Sharifi","orcid":"https://orcid.org/0000-0003-2681-2907","observed_orcids":["https://orcid.org/0000-0003-2681-2907"]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roholah Sharifi","raw_affiliation_strings":["Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037566394","display_name":"Soudabe Mahmoudzadeh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Soudabe Mahmoudzadeh","raw_affiliation_strings":["Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024788677","display_name":"Mohammad Mirazul Islam","orcid":"https://orcid.org/0000-0001-9999-0427","observed_orcids":["https://orcid.org/0000-0001-9999-0427"]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohammad Mirazul Islam","raw_affiliation_strings":["Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062303435","display_name":"Darrell J. Koza","orcid":"https://orcid.org/0000-0002-6031-9991","observed_orcids":["https://orcid.org/0000-0002-6031-9991"]},"institutions":[{"id":"https://openalex.org/I203331390","display_name":"Eastern Connecticut State University","ror":"https://ror.org/01mhgwt57","country_code":"US","type":"education","lineage":["https://openalex.org/I203331390","https://openalex.org/I4210132746"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Darrell Koza","raw_affiliation_strings":["Department of Science, Eastern Connecticut State University, Willimantic, CT, 06226 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Science, Eastern Connecticut State University, Willimantic, CT, 06226 USA","institution_ids":["https://openalex.org/I203331390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060669518","display_name":"Claes Henrik Dohlman","orcid":"https://orcid.org/0000-0002-6120-8177","observed_orcids":["https://orcid.org/0000-0002-6120-8177"]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Claes H. Dohlman","raw_affiliation_strings":["Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030299442","display_name":"James Chodosh","orcid":"https://orcid.org/0000-0002-7463-1599","observed_orcids":["https://orcid.org/0000-0002-7463-1599"]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Chodosh","raw_affiliation_strings":["Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030667111","display_name":"Miguel Gonz\u00e1lez\u2010Andrades","orcid":"https://orcid.org/0000-0003-4632-1267","observed_orcids":["https://orcid.org/0000-0003-4632-1267"]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210093628","display_name":"Instituto Maim\u00f3nides de Investigaci\u00f3n Biom\u00e9dica de C\u00f3rdoba","ror":"https://ror.org/00j9b6f88","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210093628"]},{"id":"https://openalex.org/I4210123675","display_name":"Hospital Universitario Reina Sof\u00eda","ror":"https://ror.org/02vtd2q19","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I158283456","https://openalex.org/I4210123675"]},{"id":"https://openalex.org/I53110688","display_name":"University of C\u00f3rdoba","ror":"https://ror.org/05yc77b46","country_code":"ES","type":"education","lineage":["https://openalex.org/I53110688"]}],"countries":["ES","US"],"is_corresponding":false,"raw_author_name":"Miguel Gonzalez\u2010Andrades","raw_affiliation_strings":["Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Department of Ophthalmology, Reina Sofia University Hospital and University of Cordoba, Cordoba, 14004 Spain","Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Department of Ophthalmology, Reina Sofia University Hospital and University of Cordoba, Cordoba, 14004 Spain","institution_ids":["https://openalex.org/I4210093628","https://openalex.org/I4210123675","https://openalex.org/I53110688"]},{"raw_affiliation_string":"Massachusetts Eye and Ear \u2013 Schepens Eye Research Institute Department of Ophthalmology Harvard Medical School  Boston MA 02114 USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":null,"fwci":0.1378,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.2893383,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"7","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.8682000041007996,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.8682000041007996,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.1136000007390976,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/poly-methyl-methacrylate","display_name":"poly(methyl methacrylate)","score":0.9990000128746033},{"id":"https://openalex.org/keywords/l-dopa","display_name":"L-DOPA","score":0.9739999771118164},{"id":"https://openalex.org/keywords/covalent-surface-functionalization","display_name":"covalent surface functionalization","score":0.9549999833106995},{"id":"https://openalex.org/keywords/biocompatibility","display_name":"biocompatibility","score":0.9190000295639038},{"id":"https://openalex.org/keywords/corneal-fibroblasts","display_name":"corneal fibroblasts","score":0.9509999752044678},{"id":"https://openalex.org/keywords/boston-keratoprosthesis","display_name":"Boston keratoprosthesis","score":0.9210000038146973},{"id":"https://openalex.org/keywords/artificial-cornea","display_name":"artificial cornea","score":0.9620000123977661},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.6129999756813049},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.6290000081062317},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.8330000042915344},{"id":"https://openalex.org/keywords/biomaterial-coatings","display_name":"biomaterial coatings","score":0.6850000023841858}],"concepts":[{"id":"https://openalex.org/C2777230088","wikidata":"https://www.wikidata.org/wiki/Q864426","display_name":"Biocompatibility","level":2,"score":0.9227222800254822},{"id":"https://openalex.org/C2777440324","wikidata":"https://www.wikidata.org/wiki/Q4161984","display_name":"Dihydroxyphenylalanine","level":3,"score":0.8075393438339233},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7599816918373108},{"id":"https://openalex.org/C115537861","wikidata":"https://www.wikidata.org/wiki/Q7645993","display_name":"Surface modification","level":2,"score":0.6959770917892456},{"id":"https://openalex.org/C2776053893","wikidata":"https://www.wikidata.org/wiki/Q6393649","display_name":"Keratoprosthesis","level":3,"score":0.682502031326294},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.6208730340003967},{"id":"https://openalex.org/C132050475","wikidata":"https://www.wikidata.org/wiki/Q736232","display_name":"Methacrylate","level":4,"score":0.5814859867095947},{"id":"https://openalex.org/C2777935641","wikidata":"https://www.wikidata.org/wiki/Q382897","display_name":"Methyl methacrylate","level":4,"score":0.5708229541778564},{"id":"https://openalex.org/C2780718992","wikidata":"https://www.wikidata.org/wiki/Q146123","display_name":"Poly(methyl methacrylate)","level":5,"score":0.5678746104240417},{"id":"https://openalex.org/C180577832","wikidata":"https://www.wikidata.org/wiki/Q127920","display_name":"Covalent bond","level":2,"score":0.5567752122879028},{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.46491724252700806},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3982633650302887},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.35845720767974854},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.3213768005371094},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.32015711069107056},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.1795429289340973},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.16742181777954102},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.1660977303981781},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.14912834763526917},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.14359498023986816},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.094414621591568},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.04884329438209534},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/admi.202070001","doi":"https://doi.org/10.1002/admi.202070001","is_oa":false,"landing_page_url":"https://doi.org/10.1002/admi.202070001","pdf_url":null,"source":{"id":"https://openalex.org/S2764385675","display_name":"Advanced Materials Interfaces","issn_l":"2196-7350","issn":["2196-7350"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Materials Interfaces","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46810001134872437}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2988294803","https://openalex.org/W2761473298","https://openalex.org/W2044297550","https://openalex.org/W2264728367","https://openalex.org/W2923856412","https://openalex.org/W2412566271","https://openalex.org/W2073301915","https://openalex.org/W1997683161","https://openalex.org/W3115488857","https://openalex.org/W2908356591"],"abstract_inverted_index":{"Poly(methyl":[0],"methacrylate)":[1],"(PMMA)":[2],"surface":[3],"is":[4],"covalently":[5],"functionalized":[6],"with":[7,56],"L-3,4-dihydroxyphenylalanine":[8],"(L-DOPA)":[9],"to":[10,41],"form":[11],"stable":[12],"coating":[13],"that":[14],"significantly":[15],"improves":[16],"the":[17,20,26,45,48],"biocompatibility":[18],"of":[19,29,44],"PMMA.":[21],"L-DOPA-functionalized":[22],"PMMA":[23],"also":[24],"preserves":[25],"phenotypic":[27],"characteristics":[28],"corneal":[30,58],"fibroblast,":[31],"supporting":[32],"cellular":[33],"adhesion,":[34],"proliferation,":[35],"and":[36,74],"migration,":[37],"which":[38],"may":[39],"lead":[40],"better":[42],"biointegration":[43],"Boston":[46],"keratoprosthesis,":[47],"most":[49],"commonly":[50],"implanted":[51],"artificial":[52],"cornea":[53],"for":[54],"patients":[55],"severe":[57],"diseases.":[59],"More":[60],"details":[61],"can":[62],"be":[63],"found":[64],"in":[65],"article":[66],"number":[67],"1900767":[68],"by":[69],"James":[70],"Chodosh,":[71],"Miguel":[72],"Gonzalez-Andrades,":[73],"co-workers.":[75]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2020-01-23T00:00:00"}