{"id":"https://openalex.org/W2998965615","doi":"https://doi.org/10.1038/s41598-019-57230-z","title":"Retrospective analysis of clinical phenotype and prognosis of hypertrophic cardiomyopathy complicated with hypertension","display_name":"Retrospective analysis of clinical phenotype and prognosis of hypertrophic cardiomyopathy complicated with hypertension","publication_year":2020,"publication_date":"2020-01-15","ids":{"openalex":"https://openalex.org/W2998965615","doi":"https://doi.org/10.1038/s41598-019-57230-z","mag":"2998965615","pmid":"https://pubmed.ncbi.nlm.nih.gov/31941943"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-019-57230-z","doi":"https://doi.org/10.1038/s41598-019-57230-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-57230-z","pdf_url":"https://www.nature.com/articles/s41598-019-57230-z.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-019-57230-z.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5116066645","display_name":"Qin Luo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qin Luo","raw_affiliation_strings":["Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jin Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jin Chen","raw_affiliation_strings":["Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082475097","display_name":"Tianhua Zhang","orcid":"https://orcid.org/0000-0002-6180-0381","observed_orcids":["https://orcid.org/0000-0002-6180-0381"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tianhua Zhang","raw_affiliation_strings":["Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080033685","display_name":"Xiaoyu Tang","orcid":"https://orcid.org/0000-0003-0445-7772","observed_orcids":["https://orcid.org/0000-0003-0445-7772"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyu Tang","raw_affiliation_strings":["Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101525530","display_name":"Bilian Yu","orcid":"https://orcid.org/0000-0002-5701-5487","observed_orcids":["https://orcid.org/0000-0002-5701-5487"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bilian Yu","raw_affiliation_strings":["Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China. yubilian@csu.edu.cn","Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China. yubilian@csu.edu.cn","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Department of Cardiovascular medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101525530"],"corresponding_institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856"],"apc_list":{"value":1870,"currency":"USD","value_usd":1870},"apc_paid":{"value":1870,"currency":"USD","value_usd":1870},"fwci":1.5458,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.84726056,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"10","issue":"1","first_page":"349","last_page":"349"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11922","display_name":"Cardiovascular Effects of Exercise","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypertrophic-cardiomyopathy","display_name":"hypertrophic cardiomyopathy","score":1.0},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9919999837875366},{"id":"https://openalex.org/keywords/clinical-phenotype","display_name":"clinical phenotype","score":0.765999972820282},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/apical-hypertrophy","display_name":"apical hypertrophy","score":0.8450000286102295},{"id":"https://openalex.org/keywords/midventricular-obstruction","display_name":"midventricular obstruction","score":0.9940000176429749},{"id":"https://openalex.org/keywords/mutation","display_name":"genetic mutations","score":0.48500001430511475},{"id":"https://openalex.org/keywords/syncope","display_name":"syncope","score":0.6710000038146973},{"id":"https://openalex.org/keywords/sudden-death","display_name":"sudden death","score":0.7120000123977661},{"id":"https://openalex.org/keywords/5-year-survival","display_name":"five-year survival","score":0.7350000143051147},{"id":"https://openalex.org/keywords/cardiac-structure-and-function","display_name":"cardiac structure and function","score":0.8230000138282776}],"concepts":[{"id":"https://openalex.org/C2780185194","wikidata":"https://www.wikidata.org/wiki/Q1364270","display_name":"Hypertrophic cardiomyopathy","level":2,"score":0.950875997543335},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8988407850265503},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7442664504051208},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6653409004211426},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.4965541958808899},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.4932045340538025},{"id":"https://openalex.org/C167414201","wikidata":"https://www.wikidata.org/wiki/Q1955391","display_name":"Muscle hypertrophy","level":2,"score":0.4729354679584503},{"id":"https://openalex.org/C2775935837","wikidata":"https://www.wikidata.org/wiki/Q202837","display_name":"Sudden cardiac death","level":2,"score":0.4657006859779358},{"id":"https://openalex.org/C2776002628","wikidata":"https://www.wikidata.org/wiki/Q1628627","display_name":"Left ventricular hypertrophy","level":3,"score":0.43573620915412903},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.4149831235408783},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.4111122786998749},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.23816394805908203},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.23088133335113525}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002312","descriptor_name":"Cardiomyopathy, Hypertrophic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41598-019-57230-z","doi":"https://doi.org/10.1038/s41598-019-57230-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-57230-z","pdf_url":"https://www.nature.com/articles/s41598-019-57230-z.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmid:31941943","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31941943","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5924541","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6962215","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6962215","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6962215","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:9b629ffb4d4448d4bf09fb22758f5e30","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/9b629ffb4d4448d4bf09fb22758f5e30","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-019-57230-z","doi":"https://doi.org/10.1038/s41598-019-57230-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-57230-z","pdf_url":"https://www.nature.com/articles/s41598-019-57230-z.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.7900000214576721,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G6768142494","display_name":"\u5185\u6e90\u6027apoO\u8c03\u63a7\u8102\u80aa\u5206\u6ccc\u529f\u80fd\u5bf9\u52a8\u8109\u7ca5\u6837\u786c\u5316\u5f71\u54cd\u7684\u7814\u7a76","funder_award_id":"81670420","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335740","display_name":"Xiangya Hospital, Central South University","ror":"https://ror.org/05akvb491"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2998965615.pdf","grobid_xml":"https://content.openalex.org/works/W2998965615.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1984068087","https://openalex.org/W1999597093","https://openalex.org/W2051978340","https://openalex.org/W2061302189","https://openalex.org/W2061377731","https://openalex.org/W2064234530","https://openalex.org/W2082231490","https://openalex.org/W2086994437","https://openalex.org/W2087447794","https://openalex.org/W2096639996","https://openalex.org/W2097618980","https://openalex.org/W2102438642","https://openalex.org/W2112354582","https://openalex.org/W2162713136","https://openalex.org/W2164740169","https://openalex.org/W2342114857","https://openalex.org/W2413495564","https://openalex.org/W2616302857","https://openalex.org/W2745956749","https://openalex.org/W2835736964","https://openalex.org/W2967058150","https://openalex.org/W3004208181","https://openalex.org/W3134574291","https://openalex.org/W3179101363","https://openalex.org/W4247028240"],"related_works":["https://openalex.org/W2006176619","https://openalex.org/W3025302051","https://openalex.org/W2067800680","https://openalex.org/W4379535143","https://openalex.org/W2999928784","https://openalex.org/W2463198152","https://openalex.org/W2531517130","https://openalex.org/W2754186320","https://openalex.org/W2773721902","https://openalex.org/W2063897389"],"abstract_inverted_index":{"We":[0],"here":[1],"studied":[2],"the":[3,53,84,115,165,179,204],"clinical":[4,44,139,180],"features,":[5],"cardiac":[6,46],"structure,":[7],"and":[8,11,29,40,48,50,80,103],"functional":[9],"changes":[10],"prognosis":[12,51,158],"of":[13,23,52,94,137,148,182,190,206],"hypertrophic":[14,208],"cardiomyopathy":[15,209],"(HCM)":[16],"patients":[17,26,31,63,121,161,184,191],"with":[18,27,64,129,162,185,192],"hypertension":[19],"(HTN).":[20],"A":[21],"total":[22],"90":[24],"HCM":[25,62,120,160,183,193],"HTN":[28,33,65,116,130,186,197],"172":[30],"without":[32],"were":[34,56,131,167],"divided":[35],"into":[36],"a":[37,153,156,200],"hypertensive":[38,207],"group":[39],"non-hypertensive":[41],"group.":[42,117],"The":[43,92],"characteristics,":[45],"structure":[47],"function,":[49],"two":[54],"groups":[55],"compared.":[57],"Our":[58],"study":[59],"found":[60,177],"that":[61,178,196],"had":[66,122],"fewer":[67],"syncope":[68],"events":[69],"in":[70,83,114,159,203],"their":[71],"medical":[72],"histories":[73],"(8%":[74],"vs.":[75,87,98,107,142],"22%,":[76],"P":[77,89,100,109,144],"<":[78,90,101,110,145],"0.01)":[79,102],"sudden":[81],"deaths":[82],"family":[85],"(3%":[86],"10%,":[88],"0.05).":[91,146],"prevalence":[93],"apical":[95],"hypertrophy":[96],"(18%":[97],"7%,":[99],"midventricular":[104],"obstruction":[105],"(26%":[106],"15%,":[108],"0.05)":[111],"was":[112],"higher":[113],"Besides,":[118],"simple":[119],"more":[123,132],"pathogenic":[124,201],"gene":[125],"mutations,":[126],"while":[127],"those":[128,189],"likely":[133],"to":[134],"have":[135],"mutations":[136],"uncertain":[138],"significance":[140],"(64%":[141],"24%,":[143],"Evaluation":[147],"5-year":[149],"survival":[150],"rate":[151],"showed":[152],"trend":[154],"for":[155],"worse":[157],"HTN,":[163],"but":[164],"results":[166],"not":[168],"statistically":[169],"insignificant":[170],"(P":[171],"=":[172],"0.065).":[173],"In":[174],"conclusion,":[175],"we":[176],"phenotypes":[181],"differed":[187],"from":[188],"alone,":[194],"suggesting":[195],"may":[198],"play":[199],"role":[202],"pathogenesis":[205],"patients.":[210]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":7},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2}],"updated_date":"2026-10-09T09:14:12.587421","created_date":"2025-10-10T00:00:00"}