{"id":"https://openalex.org/W2998069397","doi":"https://doi.org/10.1111/bph.14953","title":"Fluorescent ligands: Bringing light to emerging GPCR paradigms","display_name":"Fluorescent ligands: Bringing light to emerging GPCR paradigms","publication_year":2019,"publication_date":"2019-12-26","ids":{"openalex":"https://openalex.org/W2998069397","doi":"https://doi.org/10.1111/bph.14953","mag":"2998069397","pmid":"https://pubmed.ncbi.nlm.nih.gov/31877233","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7042119"},"language":"en","primary_location":{"id":"doi:10.1111/bph.14953","doi":"https://doi.org/10.1111/bph.14953","is_oa":false,"landing_page_url":"https://doi.org/10.1111/bph.14953","pdf_url":null,"source":{"id":"https://openalex.org/S55107261","display_name":"British Journal of Pharmacology","issn_l":"0007-1188","issn":["0007-1188","1476-5381"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Pharmacology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7042119/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000818586","display_name":"Mark Soave","orcid":"https://orcid.org/0000-0002-9199-1772","observed_orcids":["https://orcid.org/0000-0002-9199-1772"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mark Soave","raw_affiliation_strings":["Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK","Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK"],"raw_orcid":"https://orcid.org/0000-0002-9199-1772","affiliations":[{"raw_affiliation_string":"Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]},{"raw_affiliation_string":"Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK","institution_ids":["https://openalex.org/I142263535","https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070048387","display_name":"Stephen J. Briddon","orcid":"https://orcid.org/0000-0001-8514-0827","observed_orcids":["https://orcid.org/0000-0001-8514-0827"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen J. Briddon","raw_affiliation_strings":["Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK","Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK"],"raw_orcid":"https://orcid.org/0000-0001-8514-0827","affiliations":[{"raw_affiliation_string":"Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]},{"raw_affiliation_string":"Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK","institution_ids":["https://openalex.org/I142263535","https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055271565","display_name":"Stephen J. Hill","orcid":"https://orcid.org/0000-0002-4424-239X","observed_orcids":["https://orcid.org/0000-0002-4424-239X"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen J. Hill","raw_affiliation_strings":["Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK","Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK"],"raw_orcid":"https://orcid.org/0000-0002-4424-239X","affiliations":[{"raw_affiliation_string":"Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]},{"raw_affiliation_string":"Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK","institution_ids":["https://openalex.org/I142263535","https://openalex.org/I79619799"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069677478","display_name":"Leigh A. Stoddart","orcid":"https://orcid.org/0000-0002-4469-0600","observed_orcids":["https://orcid.org/0000-0002-4469-0600"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Leigh A. Stoddart","raw_affiliation_strings":["Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK","Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK"],"raw_orcid":"https://orcid.org/0000-0002-4469-0600","affiliations":[{"raw_affiliation_string":"Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK","institution_ids":["https://openalex.org/I142263535"]},{"raw_affiliation_string":"Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK","institution_ids":["https://openalex.org/I142263535","https://openalex.org/I79619799"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5069677478"],"corresponding_institution_ids":["https://openalex.org/I142263535","https://openalex.org/I79619799"],"apc_list":{"value":4000,"currency":"USD","value_usd":4000},"apc_paid":null,"fwci":0.6426,"has_fulltext":false,"cited_by_count":88,"citation_normalized_percentile":{"value":0.5594584,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"177","issue":"5","first_page":"978","last_page":"991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluorescent-ligands","display_name":"fluorescent ligands","score":0.9909999966621399},{"id":"https://openalex.org/keywords/g-protein-coupled-receptors","display_name":"G protein-coupled receptors","score":0.9929999709129333},{"id":"https://openalex.org/keywords/gpcr-pharmacology","display_name":"GPCR pharmacology","score":0.9139999747276306},{"id":"https://openalex.org/keywords/ligand-binding-kinetics","display_name":"ligand binding kinetics","score":0.8870000243186951},{"id":"https://openalex.org/keywords/intracellular-signaling","display_name":"intracellular signaling","score":0.9440000057220459},{"id":"https://openalex.org/keywords/single-molecule-microscopy","display_name":"single-molecule microscopy","score":0.7720000147819519},{"id":"https://openalex.org/keywords/fluorescent-probes","display_name":"fluorescent probes","score":0.6420000195503235},{"id":"https://openalex.org/keywords/in-vivo-efficacy","display_name":"in vivo efficacy","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C135285700","wikidata":"https://www.wikidata.org/wiki/Q38173","display_name":"G protein-coupled receptor","level":3,"score":0.672026515007019},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.530908465385437},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4185834228992462},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40578120946884155},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.35850989818573},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35620540380477905},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33016762137413025},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3127894997596741},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2667083740234375},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1819605827331543},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.06715652346611023},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/bph.14953","doi":"https://doi.org/10.1111/bph.14953","is_oa":false,"landing_page_url":"https://doi.org/10.1111/bph.14953","pdf_url":null,"source":{"id":"https://openalex.org/S55107261","display_name":"British Journal of Pharmacology","issn_l":"0007-1188","issn":["0007-1188","1476-5381"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Pharmacology","raw_type":"journal-article"},{"id":"pmid:31877233","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31877233","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British journal of pharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7042119","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7042119/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br J Pharmacol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7042119","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7042119/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br J Pharmacol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4000000059604645,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1500634921","display_name":"Use of fluorescence correlation spectroscopy to study GPCR oligomerisation and allosterism in membrane micro domains of single living cells.","funder_award_id":"MR/N020081/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":115,"referenced_works":["https://openalex.org/W243325842","https://openalex.org/W322416743","https://openalex.org/W1027059434","https://openalex.org/W1492380293","https://openalex.org/W1510403623","https://openalex.org/W1556070936","https://openalex.org/W1592221939","https://openalex.org/W1663154925","https://openalex.org/W1733847523","https://openalex.org/W1767831672","https://openalex.org/W1858777777","https://openalex.org/W1873461223","https://openalex.org/W1895993106","https://openalex.org/W1957585951","https://openalex.org/W1963765655","https://openalex.org/W1977136964","https://openalex.org/W1981956283","https://openalex.org/W1986267285","https://openalex.org/W1987062630","https://openalex.org/W1996828751","https://openalex.org/W1998764060","https://openalex.org/W2000814865","https://openalex.org/W2003868977","https://openalex.org/W2005517577","https://openalex.org/W2006803138","https://openalex.org/W2007337947","https://openalex.org/W2008525757","https://openalex.org/W2008628499","https://openalex.org/W2015087988","https://openalex.org/W2017773142","https://openalex.org/W2020912046","https://openalex.org/W2029701200","https://openalex.org/W2030556696","https://openalex.org/W2031110651","https://openalex.org/W2032319774","https://openalex.org/W2049253479","https://openalex.org/W2051973898","https://openalex.org/W2051994079","https://openalex.org/W2053409539","https://openalex.org/W2059538452","https://openalex.org/W2064815984","https://openalex.org/W2069834195","https://openalex.org/W2078646143","https://openalex.org/W2082956345","https://openalex.org/W2097472214","https://openalex.org/W2099576957","https://openalex.org/W2107567947","https://openalex.org/W2107712898","https://openalex.org/W2118333549","https://openalex.org/W2121326081","https://openalex.org/W2121987541","https://openalex.org/W2122174098","https://openalex.org/W2125343147","https://openalex.org/W2126132542","https://openalex.org/W2136472480","https://openalex.org/W2137887442","https://openalex.org/W2139129258","https://openalex.org/W2145541768","https://openalex.org/W2151186972","https://openalex.org/W2156624898","https://openalex.org/W2163965515","https://openalex.org/W2166167634","https://openalex.org/W2166810828","https://openalex.org/W2191622804","https://openalex.org/W2206592209","https://openalex.org/W2207535250","https://openalex.org/W2210549414","https://openalex.org/W2220647489","https://openalex.org/W2254560754","https://openalex.org/W2268919464","https://openalex.org/W2288077045","https://openalex.org/W2289472445","https://openalex.org/W2319050564","https://openalex.org/W2319095392","https://openalex.org/W2320170875","https://openalex.org/W2327089235","https://openalex.org/W2336745856","https://openalex.org/W2337688087","https://openalex.org/W2394909441","https://openalex.org/W2398650198","https://openalex.org/W2417795456","https://openalex.org/W2484875726","https://openalex.org/W2528392802","https://openalex.org/W2581108298","https://openalex.org/W2604285083","https://openalex.org/W2607348308","https://openalex.org/W2620827705","https://openalex.org/W2623124886","https://openalex.org/W2750671143","https://openalex.org/W2760367307","https://openalex.org/W2765598356","https://openalex.org/W2771328536","https://openalex.org/W2772089777","https://openalex.org/W2780149280","https://openalex.org/W2782064635","https://openalex.org/W2782382515","https://openalex.org/W2784672273","https://openalex.org/W2786545656","https://openalex.org/W2786911310","https://openalex.org/W2791135672","https://openalex.org/W2793116285","https://openalex.org/W2886953869","https://openalex.org/W2889163572","https://openalex.org/W2892830761","https://openalex.org/W2898899480","https://openalex.org/W2900584215","https://openalex.org/W2904498511","https://openalex.org/W2908579861","https://openalex.org/W2912561327","https://openalex.org/W2923589344","https://openalex.org/W2947170120","https://openalex.org/W2962123024","https://openalex.org/W2984194970","https://openalex.org/W2985843002","https://openalex.org/W3025891904"],"related_works":["https://openalex.org/W322416743","https://openalex.org/W2327089235","https://openalex.org/W2074660549","https://openalex.org/W2170933942","https://openalex.org/W2030645130","https://openalex.org/W2599024405","https://openalex.org/W52170103","https://openalex.org/W1979747061","https://openalex.org/W2779347450","https://openalex.org/W2893816517"],"abstract_inverted_index":{"In":[0],"recent":[1],"years,":[2],"several":[3],"novel":[4],"aspects":[5],"of":[6,25,36,44,64,78,83,107],"GPCR":[7,94],"pharmacology":[8],"have":[9,30,39],"been":[10,31],"described,":[11],"which":[12,38],"are":[13],"thought":[14],"to":[15,33,53,59,69,110],"play":[16],"a":[17,26,61],"role":[18],"in":[19,22,70,80,86],"determining":[20],"the":[21,42,51,55,79,93,105],"vivo":[23,71],"efficacy":[24],"compound.":[27],"Fluorescent":[28,48],"ligands":[29,49,85,109],"used":[32],"study":[34,111],"many":[35],"these,":[37],"also":[40],"required":[41],"development":[43],"new":[45],"experimental":[46],"approaches.":[47],"offer":[50],"potential":[52],"use":[54,82,106],"same":[56],"fluorescent":[57,84,108],"probe":[58],"perform":[60],"broad":[62],"range":[63],"experiments,":[65],"from":[66],"single-molecule":[67],"microscopy":[68],"BRET.":[72],"This":[73],"review":[74],"provides":[75],"an":[76],"overview":[77],"vitro":[81],"further":[87],"understanding":[88],"emerging":[89],"pharmacological":[90],"paradigms":[91],"within":[92],"field,":[95],"including":[96],"ligand-binding":[97],"kinetics,":[98],"allosterism":[99],"and":[100],"intracellular":[101],"signalling,":[102],"along":[103],"with":[104],"physiologically":[112],"relevant":[113],"therapeutic":[114],"agents.":[115]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-01-10T00:00:00"}