{"id":"https://openalex.org/W2998048947","doi":"https://doi.org/10.1097/tp.0000000000003088","title":"Kidney Transplant Outcomes in Patients With Adenine Phosphoribosyltransferase Deficiency","display_name":"Kidney Transplant Outcomes in Patients With Adenine Phosphoribosyltransferase Deficiency","publication_year":2019,"publication_date":"2019-12-26","ids":{"openalex":"https://openalex.org/W2998048947","doi":"https://doi.org/10.1097/tp.0000000000003088","mag":"2998048947","pmid":"https://pubmed.ncbi.nlm.nih.gov/31880754","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7316615"},"language":"en","primary_location":{"id":"doi:10.1097/tp.0000000000003088","doi":"https://doi.org/10.1097/tp.0000000000003088","is_oa":false,"landing_page_url":"https://doi.org/10.1097/tp.0000000000003088","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC7316615","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031869919","display_name":"Hrafnhildur Linnet Runolfsdottir","orcid":"https://orcid.org/0000-0003-1826-1383","observed_orcids":["https://orcid.org/0000-0003-1826-1383"]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]},{"id":"https://openalex.org/I4210106610","display_name":"National University Hospital of Iceland","ror":"https://ror.org/011k7k191","country_code":"IS","type":"healthcare","lineage":["https://openalex.org/I4210106610"]}],"countries":["IS"],"is_corresponding":false,"raw_author_name":"Hrafnhildur Linnet Runolfsdottir","raw_affiliation_strings":["Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland","Internal Medicine and Rehabilitation Services, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland","institution_ids":["https://openalex.org/I165368041"]},{"raw_affiliation_string":"Internal Medicine and Rehabilitation Services, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland","institution_ids":["https://openalex.org/I4210106610"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060577916","display_name":"Run\u00f3lfur P\u00e1lsson","orcid":"https://orcid.org/0000-0001-6763-1702","observed_orcids":["https://orcid.org/0000-0001-6763-1702"]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]},{"id":"https://openalex.org/I4210106610","display_name":"National University Hospital of Iceland","ror":"https://ror.org/011k7k191","country_code":"IS","type":"healthcare","lineage":["https://openalex.org/I4210106610"]}],"countries":["IS"],"is_corresponding":false,"raw_author_name":"Runolfur Palsson","raw_affiliation_strings":["Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland","Internal Medicine and Rehabilitation Services, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland","institution_ids":["https://openalex.org/I165368041"]},{"raw_affiliation_string":"Internal Medicine and Rehabilitation Services, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland","institution_ids":["https://openalex.org/I4210106610"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084709805","display_name":"Inger M. Sch. Agustsdottir","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210106610","display_name":"National University Hospital of Iceland","ror":"https://ror.org/011k7k191","country_code":"IS","type":"healthcare","lineage":["https://openalex.org/I4210106610"]}],"countries":["IS"],"is_corresponding":false,"raw_author_name":"Inger M. Sch. Agustsdottir","raw_affiliation_strings":["Children\u2019s Medical Center, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children\u2019s Medical Center, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland","institution_ids":["https://openalex.org/I4210106610"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091364019","display_name":"\u00d3lafur S. Indridason","orcid":"https://orcid.org/0000-0001-8509-6598","observed_orcids":["https://orcid.org/0000-0001-8509-6598"]},"institutions":[{"id":"https://openalex.org/I4210106610","display_name":"National University Hospital of Iceland","ror":"https://ror.org/011k7k191","country_code":"IS","type":"healthcare","lineage":["https://openalex.org/I4210106610"]}],"countries":["IS"],"is_corresponding":false,"raw_author_name":"Olafur S. Indridason","raw_affiliation_strings":["Internal Medicine and Rehabilitation Services, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine and Rehabilitation Services, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland","institution_ids":["https://openalex.org/I4210106610"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058478767","display_name":"Jennifer S.Y. Li","orcid":"https://orcid.org/0000-0003-0186-8613","observed_orcids":["https://orcid.org/0000-0003-0186-8613"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I4210145422","display_name":"Westmead Institute for Medical Research","ror":"https://ror.org/04zj3ra44","country_code":"AU","type":"facility","lineage":["https://openalex.org/I4210145422"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jennifer Li","raw_affiliation_strings":["Centre for Transplant and Renal Research, Westmead Institute for Medical Research, Sydney University, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Transplant and Renal Research, Westmead Institute for Medical Research, Sydney University, Sydney, Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I4210145422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085694984","display_name":"Myriam Dao","orcid":"https://orcid.org/0000-0001-5505-1364","observed_orcids":["https://orcid.org/0000-0001-5505-1364"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Myriam Dao","raw_affiliation_strings":["Department of Nephrology-Transplantation, Necker Hospital, APHP, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology-Transplantation, Necker Hospital, APHP, Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025976062","display_name":"Bertrand Knebelmann","orcid":"https://orcid.org/0000-0002-8115-7303","observed_orcids":["https://orcid.org/0000-0002-8115-7303"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]},{"id":"https://openalex.org/I4210091437","display_name":"Sorbonne Paris Cit\u00e9","ror":"https://ror.org/001z21q04","country_code":"FR","type":"other","lineage":["https://openalex.org/I204730241","https://openalex.org/I4210091437"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bertrand Knebelmann","raw_affiliation_strings":["Department of Nephrology-Transplantation, Necker Hospital, APHP, Paris, France","D\u00e9partement Biologie cellulaire, INSERM U1151, Institut Necker Enfants Malades, Paris, France","Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology-Transplantation, Necker Hospital, APHP, Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"D\u00e9partement Biologie cellulaire, INSERM U1151, Institut Necker Enfants Malades, Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I154526488","https://openalex.org/I4210086369"]},{"raw_affiliation_string":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France","institution_ids":["https://openalex.org/I4210091437","https://openalex.org/I4387156284"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081154709","display_name":"Dawn S. Milliner","orcid":"https://orcid.org/0000-0003-4799-1668","observed_orcids":["https://orcid.org/0000-0003-4799-1668"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dawn S. Milliner","raw_affiliation_strings":["Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035482483","display_name":"Vidar Orn Edvardsson","orcid":"https://orcid.org/0000-0002-4204-9342","observed_orcids":["https://orcid.org/0000-0002-4204-9342"]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]},{"id":"https://openalex.org/I4210106610","display_name":"National University Hospital of Iceland","ror":"https://ror.org/011k7k191","country_code":"IS","type":"healthcare","lineage":["https://openalex.org/I4210106610"]}],"countries":["IS"],"is_corresponding":true,"raw_author_name":"Vidar O. Edvardsson","raw_affiliation_strings":["Children\u2019s Medical Center, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland","Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children\u2019s Medical Center, Landspitali\u2013The National University Hospital of Iceland, Reykjavik, Iceland","institution_ids":["https://openalex.org/I4210106610"]},{"raw_affiliation_string":"Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland","institution_ids":["https://openalex.org/I165368041"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5035482483"],"corresponding_institution_ids":["https://openalex.org/I165368041","https://openalex.org/I4210106610"],"apc_list":null,"apc_paid":null,"fwci":1.475,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.78831845,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"104","issue":"10","first_page":"2120","last_page":"2128"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10606","display_name":"Kidney Stones and Urolithiasis Treatments","score":0.016599999740719795,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adenine-phosphoribosyltransferase-deficiency","display_name":"adenine phosphoribosyltransferase deficiency","score":0.9990000128746033},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/xanthine-oxidoreductase-inhibitors","display_name":"xanthine oxidoreductase inhibitors","score":0.9330000281333923},{"id":"https://openalex.org/keywords/allograft-survival","display_name":"allograft survival","score":0.9580000042915344},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.906000018119812},{"id":"https://openalex.org/keywords/kidney-stones","display_name":"kidney stones","score":0.8849999904632568},{"id":"https://openalex.org/keywords/glomerular-filtration-rate","display_name":"glomerular filtration rate","score":0.8349999785423279}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8095840215682983},{"id":"https://openalex.org/C40507961","wikidata":"https://www.wikidata.org/wiki/Q355965","display_name":"Adenine phosphoribosyltransferase","level":4,"score":0.8037004470825195},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.7294390201568604},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6632274985313416},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.6368823647499084},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.6221253275871277},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.565209686756134},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5630978345870972},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5578808188438416},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.548244833946228},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.35094255208969116},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08775362372398376},{"id":"https://openalex.org/C2776476023","wikidata":"https://www.wikidata.org/wiki/Q188261","display_name":"Purine","level":3,"score":0.06898483633995056},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.05651417374610901},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069465","descriptor_name":"Febuxostat","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000228","descriptor_name":"Adenine Phosphoribosyltransferase","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000493","descriptor_name":"Allopurinol","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005060","descriptor_name":"Europe","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008661","descriptor_name":"Metabolism, Inborn Errors","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D008661","descriptor_name":"Metabolism, Inborn Errors","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D008661","descriptor_name":"Metabolism, Inborn Errors","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009517","descriptor_name":"New South Wales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014969","descriptor_name":"Xanthine Oxidase","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052878","descriptor_name":"Urolithiasis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D052878","descriptor_name":"Urolithiasis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D052878","descriptor_name":"Urolithiasis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1097/tp.0000000000003088","doi":"https://doi.org/10.1097/tp.0000000000003088","is_oa":false,"landing_page_url":"https://doi.org/10.1097/tp.0000000000003088","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},{"id":"pmid:31880754","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31880754","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:7371056","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7316615","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7316615","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7316615/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Transplantation","raw_type":"Text"},{"id":"pmh:oai:www.hirsla.lsh.is:2336/621575","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2336/621575","pdf_url":null,"source":{"id":"https://openalex.org/S4306401083","display_name":"Hirsla (Landsp\u00edtali University Hospital)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210106610","host_organization_name":"National University Hospital of Iceland","host_organization_lineage":["https://openalex.org/I4210106610"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Transplantation","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:7371056","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7316615","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G7211161323","display_name":"Nephrolithiasis and Kidney Failure: the Rare Kidney Stone Consortium","funder_award_id":"U54DK083908","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1897393730","https://openalex.org/W1947370771","https://openalex.org/W1977827803","https://openalex.org/W1991697026","https://openalex.org/W2035025829","https://openalex.org/W2056557519","https://openalex.org/W2070588679","https://openalex.org/W2072606734","https://openalex.org/W2078489900","https://openalex.org/W2083929656","https://openalex.org/W2085119317","https://openalex.org/W2087936282","https://openalex.org/W2093071489","https://openalex.org/W2097606799","https://openalex.org/W2116831306","https://openalex.org/W2121218600","https://openalex.org/W2122855609","https://openalex.org/W2130255979","https://openalex.org/W2135083990","https://openalex.org/W2138285875","https://openalex.org/W2155965977","https://openalex.org/W2170801768","https://openalex.org/W2221915786","https://openalex.org/W2520740008","https://openalex.org/W2607031541","https://openalex.org/W2773903807","https://openalex.org/W2944049951","https://openalex.org/W4392777592"],"related_works":["https://openalex.org/W4394281268","https://openalex.org/W4399748783","https://openalex.org/W7165376623","https://openalex.org/W2159316522","https://openalex.org/W2221915786","https://openalex.org/W1947370771","https://openalex.org/W2135083990","https://openalex.org/W7099248484","https://openalex.org/W4417194566","https://openalex.org/W2775366028"],"abstract_inverted_index":{"BACKGROUND:":[0],"Adenine":[1],"phosphoribosyltransferase":[2],"(APRT)":[3],"deficiency":[4,41,214,247],"is":[5,19,225,240],"a":[6,226],"rare,":[7],"hereditary":[8],"cause":[9,228],"of":[10,29,36,53,229,245],"kidney":[11,15,37,121,252],"stones":[12],"and":[13,66,76,157,191,248],"chronic":[14],"disease":[16],"(CKD)":[17],"which":[18],"characterized":[20],"by":[21],"2,8-dihydroxyadenine":[22],"renal":[23],"parenchymal":[24],"crystal":[25],"deposition.":[26],"The":[27,74,95,167],"aim":[28],"this":[30],"study":[31],"was":[32,89,98,127,155,178,187,202],"to":[33,81,100,105],"examine":[34],"outcomes":[35,103,209],"transplantation":[38,126,149],"in":[39,48,63,71,159,212,222,233],"APRT":[40,50,213,246],"patients.":[42,235],"METHODS:":[43],"Included":[44],"were":[45,79],"13":[46],"patients":[47,116,132,142,215],"the":[49,54,92,160],"Deficiency":[51],"Registry":[52],"Rare":[55],"Kidney":[56,207],"Stone":[57],"Consortium,":[58],"2":[59,67,161,175],"from":[60,68],"Westmead":[61],"Hospital":[62,70],"Sydney,":[64],"Australia,":[65],"Necker":[69],"Paris,":[72],"France.":[73],"CKD-EPI":[75],"CKiD":[77],"equations":[78],"used":[80,99],"calculate":[82],"glomerular":[83,171],"filtration":[84,172],"rate":[85,173],"estimates.":[86],"Allograft":[87],"survival":[88,154],"analyzed":[90],"employing":[91],"Kaplan-Meier":[93],"method.":[94],"Wilcoxon-Mann-Whitney":[96],"test":[97],"compare":[101],"alllograft":[102],"according":[104],"xanthine":[106],"oxidoreductase":[107],"(XOR)":[108],"inhibitor":[109,135,185,218],"treatment":[110,147,201,224],"status":[111],"at":[112,124,174],"transplantation.":[113,253],"RESULTS:":[114],"Seventeen":[115],"(9":[117],"females)":[118],"received":[119,133],"22":[120],"transplants.":[122],"Age":[123],"first":[125],"47.2":[128],"(14.9-67.0)":[129],"years.":[130],"Ten":[131],"XOR":[134,184,217],"therapy":[136,186,219],"pretransplant":[137],"(11":[138,150],"allografts),":[139],"while":[140],"8":[141],"did":[143],"not":[144,203],"receive":[145],"such":[146,200,223],"before":[148,189,251],"allografts).":[151],"Two-year":[152],"allograft":[153,208],"91%":[156],"55%":[158],"groups,":[162],"respectively":[163],"(P":[164,196],"=":[165,197],"0.16).":[166],"median":[168],"(range)":[169],"estimated":[170],"years":[176],"posttransplant":[177],"61.3":[179],"(24.0-90.0)":[180],"mL/min/1.73":[181,194],"m":[182,195],"when":[183,199],"initiated":[188],"transplantation,":[190],"16.2":[192],"(10.0-39.0)":[193],"0.009)":[198],"administered":[204],"pretransplant.":[205,220],"CONCLUSIONS:":[206],"are":[210],"good":[211],"beginning":[216],"Delay":[221],"major":[227],"premature":[230],"graft":[231],"loss":[232],"these":[234],"Increased":[236],"awareness":[237],"among":[238],"clinicians":[239],"imperative,":[241],"promoting":[242],"early":[243],"diagnosis":[244],"pharmacotherapy":[249],"initiation":[250]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-01-10T00:00:00"}