{"id":"https://openalex.org/W2997973386","doi":"https://doi.org/10.1016/j.jddst.2019.101463","title":"Aqueous solubility of kinase inhibitors: II the effect of hexadimethrine bromide on the dovitinib/\u03b3-cyclodextrin complexation","display_name":"Aqueous solubility of kinase inhibitors: II the effect of hexadimethrine bromide on the dovitinib/\u03b3-cyclodextrin complexation","publication_year":2019,"publication_date":"2019-12-23","ids":{"openalex":"https://openalex.org/W2997973386","doi":"https://doi.org/10.1016/j.jddst.2019.101463","mag":"2997973386"},"language":"en","primary_location":{"id":"doi:10.1016/j.jddst.2019.101463","doi":"https://doi.org/10.1016/j.jddst.2019.101463","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jddst.2019.101463","pdf_url":null,"source":{"id":"https://openalex.org/S97205441","display_name":"Journal of Drug Delivery Science and Technology","issn_l":"1773-2247","issn":["1773-2247","2588-8943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery Science and Technology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028003293","display_name":"Pitsiree Praphanwittaya","orcid":"https://orcid.org/0000-0003-2900-4294","observed_orcids":["https://orcid.org/0000-0003-2900-4294"]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]}],"countries":["IS"],"is_corresponding":false,"raw_author_name":"Pitsiree Praphanwittaya","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, University of Iceland, Hofsvallagata 53, IS-107, Reykjavik, Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, University of Iceland, Hofsvallagata 53, IS-107, Reykjavik, Iceland","institution_ids":["https://openalex.org/I165368041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089586449","display_name":"Phennapha Saokham","orcid":"https://orcid.org/0000-0003-4581-7498","observed_orcids":["https://orcid.org/0000-0003-4581-7498"]},"institutions":[{"id":"https://openalex.org/I89226531","display_name":"Rangsit University","ror":"https://ror.org/01cqcrc47","country_code":"TH","type":"education","lineage":["https://openalex.org/I89226531"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Phennapha Saokham","raw_affiliation_strings":["Department of Manufacturing Pharmacy, Faculty of Pharmacy, Rangsit University, Pathum Thani, 12000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Manufacturing Pharmacy, Faculty of Pharmacy, Rangsit University, Pathum Thani, 12000, Thailand","institution_ids":["https://openalex.org/I89226531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067966639","display_name":"Phatsawee Jansook","orcid":"https://orcid.org/0000-0001-7114-8991","observed_orcids":["https://orcid.org/0000-0001-7114-8991"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Phatsawee Jansook","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Chulalongkorn University, 254 Payathai Road, Pathumwan, Bangkok, 10330, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Chulalongkorn University, 254 Payathai Road, Pathumwan, Bangkok, 10330, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062520026","display_name":"\u00deorsteinn Loftsson","orcid":"https://orcid.org/0000-0002-9439-1553","observed_orcids":["https://orcid.org/0000-0002-9439-1553"]},"institutions":[{"id":"https://openalex.org/I165368041","display_name":"University of Iceland","ror":"https://ror.org/01db6h964","country_code":"IS","type":"education","lineage":["https://openalex.org/I165368041"]}],"countries":["IS"],"is_corresponding":true,"raw_author_name":"Thorsteinn Loftsson","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, University of Iceland, Hofsvallagata 53, IS-107, Reykjavik, Iceland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, University of Iceland, Hofsvallagata 53, IS-107, Reykjavik, Iceland","institution_ids":["https://openalex.org/I165368041"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5062520026"],"corresponding_institution_ids":["https://openalex.org/I165368041"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.8832,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.66223266,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"55","issue":null,"first_page":"101463","last_page":"101463"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11881","display_name":"Crystallization and Solubility Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dovitinib","display_name":"dovitinib","score":1.0},{"id":"https://openalex.org/keywords/hexadimethrine-bromide","display_name":"hexadimethrine bromide","score":0.8679999709129333},{"id":"https://openalex.org/keywords/gamma-cyclodextrin","display_name":"\u03b3-cyclodextrin","score":0.9739999771118164},{"id":"https://openalex.org/keywords/water-solubility-enhancement","display_name":"aqueous solubility enhancement","score":0.8050000071525574},{"id":"https://openalex.org/keywords/ternary-inclusion-complex","display_name":"ternary inclusion complex","score":0.652999997138977},{"id":"https://openalex.org/keywords/phase-solubility-diagram","display_name":"phase solubility diagram","score":0.7390000224113464},{"id":"https://openalex.org/keywords/kinase-inhibitors","display_name":"kinase inhibitors","score":0.6769999861717224},{"id":"https://openalex.org/keywords/drug-solubilization","display_name":"drug solubilization","score":0.7310000061988831},{"id":"https://openalex.org/keywords/solid-state-characterization","display_name":"solid-state characterization","score":0.4410000145435333}],"concepts":[{"id":"https://openalex.org/C155574463","wikidata":"https://www.wikidata.org/wiki/Q170731","display_name":"Solubility","level":2,"score":0.791409969329834},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7249240875244141},{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.6626158952713013},{"id":"https://openalex.org/C39519442","wikidata":"https://www.wikidata.org/wiki/Q904893","display_name":"Differential scanning calorimetry","level":2,"score":0.6484372019767761},{"id":"https://openalex.org/C2779433975","wikidata":"https://www.wikidata.org/wiki/Q40417805","display_name":"Cyclodextrin","level":2,"score":0.5770785808563232},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.5729727149009705},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.5532568693161011},{"id":"https://openalex.org/C160892712","wikidata":"https://www.wikidata.org/wiki/Q901559","display_name":"Fourier transform infrared spectroscopy","level":2,"score":0.4898497760295868},{"id":"https://openalex.org/C64452783","wikidata":"https://www.wikidata.org/wiki/Q1524945","display_name":"Ternary operation","level":2,"score":0.43431156873703003},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.33068686723709106},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.14129993319511414},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jddst.2019.101463","doi":"https://doi.org/10.1016/j.jddst.2019.101463","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jddst.2019.101463","pdf_url":null,"source":{"id":"https://openalex.org/S97205441","display_name":"Journal of Drug Delivery Science and Technology","issn_l":"1773-2247","issn":["1773-2247","2588-8943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery Science and Technology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321020","display_name":"Icelandic Centre for Research","ror":"https://ror.org/03srneg48"},{"id":"https://openalex.org/F4320323298","display_name":"H\u00e1sk\u00f3li \u00cdslands","ror":"https://ror.org/01db6h964"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W33330520","https://openalex.org/W132053806","https://openalex.org/W154187383","https://openalex.org/W620749124","https://openalex.org/W1515288612","https://openalex.org/W1973198597","https://openalex.org/W1975654500","https://openalex.org/W1980459622","https://openalex.org/W1989310511","https://openalex.org/W1994720314","https://openalex.org/W2015123669","https://openalex.org/W2024061701","https://openalex.org/W2036138053","https://openalex.org/W2039237662","https://openalex.org/W2048253785","https://openalex.org/W2051728712","https://openalex.org/W2052755218","https://openalex.org/W2058206040","https://openalex.org/W2059102466","https://openalex.org/W2074582913","https://openalex.org/W2075264499","https://openalex.org/W2075268393","https://openalex.org/W2080081537","https://openalex.org/W2082814891","https://openalex.org/W2085151683","https://openalex.org/W2090428959","https://openalex.org/W2091612694","https://openalex.org/W2094153855","https://openalex.org/W2143555751","https://openalex.org/W2149131992","https://openalex.org/W2171961428","https://openalex.org/W2255754031","https://openalex.org/W2267792047","https://openalex.org/W2283449839","https://openalex.org/W2328961664","https://openalex.org/W2342776814","https://openalex.org/W2344440858","https://openalex.org/W2345700847","https://openalex.org/W2418160741","https://openalex.org/W2518314318","https://openalex.org/W2526309729","https://openalex.org/W2593198694","https://openalex.org/W2605156143","https://openalex.org/W2747559760","https://openalex.org/W2754508804","https://openalex.org/W2780232212","https://openalex.org/W2890509806","https://openalex.org/W2914072100","https://openalex.org/W2950596925","https://openalex.org/W2994765193","https://openalex.org/W4211229735","https://openalex.org/W4299383801"],"related_works":["https://openalex.org/W3040941814","https://openalex.org/W2994765193","https://openalex.org/W3048478789","https://openalex.org/W4223624274","https://openalex.org/W2145532552","https://openalex.org/W4311874358","https://openalex.org/W2099771074","https://openalex.org/W1842477439","https://openalex.org/W1965501183","https://openalex.org/W7097940071"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2020-01-10T00:00:00"}