{"id":"https://openalex.org/W29973019","doi":null,"title":"Chronic stress and ageing : effects on immune function","display_name":"Chronic stress and ageing : effects on immune function","publication_year":2014,"publication_date":"2014-12-01","ids":{"openalex":"https://openalex.org/W29973019","mag":"29973019"},"language":"en","primary_location":{"id":"pmh:oai:etheses.bham.ac.uk:5365","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/5365/1/Vitlic14PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/5365/1/Vitlic14PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://etheses.bham.ac.uk/5365/1/Vitlic14PhD.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073575999","display_name":"Ana Vitli\u0107","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ana Vitli\u0107","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5073575999"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12626","display_name":"Cancer, Stress, Anesthesia, and Immune Response","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14313","display_name":"Health and Well-being Studies","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-stress","display_name":"chronic stress","score":0.9990000128746033},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.9679999947547913},{"id":"https://openalex.org/keywords/immune-function","display_name":"immune function","score":0.871999979019165},{"id":"https://openalex.org/keywords/immunosenescence","display_name":"immunosenescence","score":0.8460000157356262},{"id":"https://openalex.org/keywords/caregiving","display_name":"caregiving","score":0.8489999771118164},{"id":"https://openalex.org/keywords/bereavement","display_name":"bereavement","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cytomegalovirus-seropositivity","display_name":"cytomegalovirus seropositivity","score":0.8569999933242798},{"id":"https://openalex.org/keywords/neutrophil-function","display_name":"neutrophil function","score":0.8730000257492065},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.8349999785423279},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.75},{"id":"https://openalex.org/keywords/dehydroepiandrosterone-sulfate","display_name":"dehydroepiandrosterone sulfate","score":0.9509999752044678},{"id":"https://openalex.org/keywords/cortisol-cortisone-ratio","display_name":"cortisol/cortisone ratio","score":0.7860000133514404},{"id":"https://openalex.org/keywords/pd-1-t-cells","display_name":"PD-1+ T cells","score":0.843999981880188},{"id":"https://openalex.org/keywords/thymic-output","display_name":"thymic output","score":0.9150000214576721},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.8640000224113464},{"id":"https://openalex.org/keywords/caregiver-burden","display_name":"caregiver burden","score":0.6240000128746033},{"id":"https://openalex.org/keywords/health-behavior","display_name":"health behavior","score":0.6439999938011169}],"concepts":[{"id":"https://openalex.org/C2779056147","wikidata":"https://www.wikidata.org/wiki/Q1660191","display_name":"Immunosenescence","level":3,"score":0.9134014844894409},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.6808595657348633},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6745284199714661},{"id":"https://openalex.org/C500499127","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Ageing","level":2,"score":0.6304738521575928},{"id":"https://openalex.org/C2778654844","wikidata":"https://www.wikidata.org/wiki/Q3305232","display_name":"Chronic stress","level":2,"score":0.6022146344184875},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5801281332969666},{"id":"https://openalex.org/C38042653","wikidata":"https://www.wikidata.org/wiki/Q1500332","display_name":"Psychoneuroimmunology","level":3,"score":0.5379859209060669},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5157723426818848},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.48981973528862},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4650868773460388},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.4425574541091919},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.40512141585350037},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3349158763885498},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.33445271849632263},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.3038685917854309},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.10954311490058899}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:etheses.bham.ac.uk:5365","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/5365/1/Vitlic14PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/5365/1/Vitlic14PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:29973019","doi":null,"is_oa":false,"landing_page_url":"http://etheses.bham.ac.uk/5365/1/Vitlic14PhD.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:etheses.bham.ac.uk:5365","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/5365/1/Vitlic14PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/5365/1/Vitlic14PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W29973019.pdf","grobid_xml":"https://content.openalex.org/works/W29973019.grobid-xml"},"referenced_works_count":352,"referenced_works":["https://openalex.org/W26073617","https://openalex.org/W130053625","https://openalex.org/W189855292","https://openalex.org/W206438966","https://openalex.org/W646331934","https://openalex.org/W1500555782","https://openalex.org/W1500806673","https://openalex.org/W1504110711","https://openalex.org/W1507372704","https://openalex.org/W1510528612","https://openalex.org/W1519063308","https://openalex.org/W1520207918","https://openalex.org/W1520948059","https://openalex.org/W1527094386","https://openalex.org/W1535319552","https://openalex.org/W1538345593","https://openalex.org/W1552837821","https://openalex.org/W1556334181","https://openalex.org/W1556397944","https://openalex.org/W1558311959","https://openalex.org/W1558352705","https://openalex.org/W1571804994","https://openalex.org/W1577251139","https://openalex.org/W1579710958","https://openalex.org/W1580217007","https://openalex.org/W1586529568","https://openalex.org/W1586850609","https://openalex.org/W1587403680","https://openalex.org/W1599119377","https://openalex.org/W1603763228","https://openalex.org/W1636089071","https://openalex.org/W1643675502","https://openalex.org/W1653360437","https://openalex.org/W1660862525","https://openalex.org/W1765011214","https://openalex.org/W1776803469","https://openalex.org/W1785250346","https://openalex.org/W1855316965","https://openalex.org/W1880149719","https://openalex.org/W1893450155","https://openalex.org/W1906900530","https://openalex.org/W1907829837","https://openalex.org/W1914444904","https://openalex.org/W1920486352","https://openalex.org/W1946284234","https://openalex.org/W1948304169","https://openalex.org/W1966094200","https://openalex.org/W1966185354","https://openalex.org/W1966596352","https://openalex.org/W1969024387","https://openalex.org/W1969189285","https://openalex.org/W1969466734","https://openalex.org/W1969644253","https://openalex.org/W1969697232","https://openalex.org/W1969758498","https://openalex.org/W1969779436","https://openalex.org/W1969836950","https://openalex.org/W1970116161","https://openalex.org/W1971311471","https://openalex.org/W1972619982","https://openalex.org/W1973076242","https://openalex.org/W1973218043","https://openalex.org/W1973251010","https://openalex.org/W1974238827","https://openalex.org/W1974834425","https://openalex.org/W1974857283","https://openalex.org/W1976544596","https://openalex.org/W1977075566","https://openalex.org/W1977987222","https://openalex.org/W1978327437","https://openalex.org/W1978494722","https://openalex.org/W1980123248","https://openalex.org/W1981299436","https://openalex.org/W1981560461","https://openalex.org/W1982086632","https://openalex.org/W1982191305","https://openalex.org/W1982482336","https://openalex.org/W1983064582","https://openalex.org/W1983282464","https://openalex.org/W1983691372","https://openalex.org/W1983858501","https://openalex.org/W1985043041","https://openalex.org/W1985380081","https://openalex.org/W1986029976","https://openalex.org/W1986231469","https://openalex.org/W1986512614","https://openalex.org/W1987071871","https://openalex.org/W1987912134","https://openalex.org/W1988566790","https://openalex.org/W1988707875","https://openalex.org/W1989218081","https://openalex.org/W1989383140","https://openalex.org/W1991365171","https://openalex.org/W1991422276","https://openalex.org/W1992362585","https://openalex.org/W1993026821","https://openalex.org/W1993688323","https://openalex.org/W1993983321","https://openalex.org/W1994797596","https://openalex.org/W1994932307","https://openalex.org/W1996094785","https://openalex.org/W1996299251","https://openalex.org/W1997282991","https://openalex.org/W1997412308","https://openalex.org/W1998267683","https://openalex.org/W1998699560","https://openalex.org/W1999177172","https://openalex.org/W1999298001","https://openalex.org/W1999981983","https://openalex.org/W2000372606","https://openalex.org/W2001529472","https://openalex.org/W2001635405","https://openalex.org/W2002176403","https://openalex.org/W2002177996","https://openalex.org/W2002313780","https://openalex.org/W2002839242","https://openalex.org/W2003454982","https://openalex.org/W2003798076","https://openalex.org/W2004098332","https://openalex.org/W2005297704","https://openalex.org/W2006017095","https://openalex.org/W2006318861","https://openalex.org/W2006521806","https://openalex.org/W2007698726","https://openalex.org/W2008034840","https://openalex.org/W2008757142","https://openalex.org/W2009782796","https://openalex.org/W2009888649","https://openalex.org/W2010610494","https://openalex.org/W2010756116","https://openalex.org/W2011783734","https://openalex.org/W2016125985","https://openalex.org/W2016980477","https://openalex.org/W2017142422","https://openalex.org/W2018684816","https://openalex.org/W2019728240","https://openalex.org/W2019814910","https://openalex.org/W2020139335","https://openalex.org/W2020228421","https://openalex.org/W2020381478","https://openalex.org/W2021723318","https://openalex.org/W2021941814","https://openalex.org/W2023095530","https://openalex.org/W2023361815","https://openalex.org/W2023734721","https://openalex.org/W2025593432","https://openalex.org/W2025609684","https://openalex.org/W2025802167","https://openalex.org/W2026429915","https://openalex.org/W2026825209","https://openalex.org/W2027042725","https://openalex.org/W2027956144","https://openalex.org/W2028255505","https://openalex.org/W2028573458","https://openalex.org/W2029234888","https://openalex.org/W2030337569","https://openalex.org/W2030414136","https://openalex.org/W2032213630","https://openalex.org/W2033817379","https://openalex.org/W2035622696","https://openalex.org/W2035715594","https://openalex.org/W2036592716","https://openalex.org/W2036653589","https://openalex.org/W2038081872","https://openalex.org/W2039268833","https://openalex.org/W2039558975","https://openalex.org/W2040854153","https://openalex.org/W2043352014","https://openalex.org/W2044159907","https://openalex.org/W2045449633","https://openalex.org/W2046342486","https://openalex.org/W2048132371","https://openalex.org/W2048165330","https://openalex.org/W2048687381","https://openalex.org/W2049056061","https://openalex.org/W2051178768","https://openalex.org/W2052925176","https://openalex.org/W2053125671","https://openalex.org/W2053209821","https://openalex.org/W2053396248","https://openalex.org/W2054754198","https://openalex.org/W2055269216","https://openalex.org/W2056184557","https://openalex.org/W2056595547","https://openalex.org/W2056605533","https://openalex.org/W2058350561","https://openalex.org/W2058373691","https://openalex.org/W2059267904","https://openalex.org/W2059642781","https://openalex.org/W2059729434","https://openalex.org/W2061168748","https://openalex.org/W2061274726","https://openalex.org/W2062200593","https://openalex.org/W2062298786","https://openalex.org/W2062349991","https://openalex.org/W2062776142","https://openalex.org/W2063102691","https://openalex.org/W2063317859","https://openalex.org/W2063595869","https://openalex.org/W2064285405","https://openalex.org/W2065373656","https://openalex.org/W2065610841","https://openalex.org/W2066503688","https://openalex.org/W2066570873","https://openalex.org/W2068227857","https://openalex.org/W2068367301","https://openalex.org/W2068392981","https://openalex.org/W2069436393","https://openalex.org/W2070740233","https://openalex.org/W2070823475","https://openalex.org/W2070883852","https://openalex.org/W2071917561","https://openalex.org/W2072170892","https://openalex.org/W2074432289","https://openalex.org/W2074989255","https://openalex.org/W2075372159","https://openalex.org/W2076349792","https://openalex.org/W2078344748","https://openalex.org/W2078659852","https://openalex.org/W2079282402","https://openalex.org/W2079427812","https://openalex.org/W2080808232","https://openalex.org/W2082099520","https://openalex.org/W2083295790","https://openalex.org/W2084185169","https://openalex.org/W2084564714","https://openalex.org/W2085368828","https://openalex.org/W2085473066","https://openalex.org/W2085838568","https://openalex.org/W2087673709","https://openalex.org/W2088274684","https://openalex.org/W2090737424","https://openalex.org/W2091350790","https://openalex.org/W2091660936","https://openalex.org/W2092090797","https://openalex.org/W2095069717","https://openalex.org/W2095893084","https://openalex.org/W2095934104","https://openalex.org/W2096422792","https://openalex.org/W2097529540","https://openalex.org/W2097692009","https://openalex.org/W2099251709","https://openalex.org/W2101613290","https://openalex.org/W2102893987","https://openalex.org/W2103059589","https://openalex.org/W2104412491","https://openalex.org/W2104939827","https://openalex.org/W2105194249","https://openalex.org/W2107337543","https://openalex.org/W2107759391","https://openalex.org/W2108244474","https://openalex.org/W2108601142","https://openalex.org/W2108724198","https://openalex.org/W2109702099","https://openalex.org/W2110695973","https://openalex.org/W2110850052","https://openalex.org/W2111549167","https://openalex.org/W2112114904","https://openalex.org/W2112497349","https://openalex.org/W2113133426","https://openalex.org/W2113187839","https://openalex.org/W2114242811","https://openalex.org/W2114899132","https://openalex.org/W2115145729","https://openalex.org/W2115516753","https://openalex.org/W2116332651","https://openalex.org/W2118424059","https://openalex.org/W2119896120","https://openalex.org/W2122080204","https://openalex.org/W2123800155","https://openalex.org/W2123865887","https://openalex.org/W2124908697","https://openalex.org/W2125110865","https://openalex.org/W2125229907","https://openalex.org/W2125870584","https://openalex.org/W2126143610","https://openalex.org/W2127008985","https://openalex.org/W2127325577","https://openalex.org/W2127903162","https://openalex.org/W2128004519","https://openalex.org/W2129524213","https://openalex.org/W2129594834","https://openalex.org/W2129652475","https://openalex.org/W2130416623","https://openalex.org/W2130900065","https://openalex.org/W2131371843","https://openalex.org/W2131480973","https://openalex.org/W2132382057","https://openalex.org/W2132539548","https://openalex.org/W2135028413","https://openalex.org/W2136385316","https://openalex.org/W2136465127","https://openalex.org/W2137079103","https://openalex.org/W2137698324","https://openalex.org/W2137839425","https://openalex.org/W2139841187","https://openalex.org/W2140066663","https://openalex.org/W2140323371","https://openalex.org/W2141013052","https://openalex.org/W2141140442","https://openalex.org/W2141683146","https://openalex.org/W2141804913","https://openalex.org/W2142877236","https://openalex.org/W2142903182","https://openalex.org/W2143135577","https://openalex.org/W2144106727","https://openalex.org/W2144729402","https://openalex.org/W2144801891","https://openalex.org/W2148695784","https://openalex.org/W2149441701","https://openalex.org/W2150539225","https://openalex.org/W2150639522","https://openalex.org/W2151313460","https://openalex.org/W2151356556","https://openalex.org/W2151454086","https://openalex.org/W2151487996","https://openalex.org/W2156646599","https://openalex.org/W2158966732","https://openalex.org/W2160352261","https://openalex.org/W2161480337","https://openalex.org/W2162846451","https://openalex.org/W2164588115","https://openalex.org/W2164808240","https://openalex.org/W2164933465","https://openalex.org/W2165244339","https://openalex.org/W2165673482","https://openalex.org/W2166281097","https://openalex.org/W2166488360","https://openalex.org/W2167350292","https://openalex.org/W2167779784","https://openalex.org/W2167928913","https://openalex.org/W2168472005","https://openalex.org/W2169581310","https://openalex.org/W2171512984","https://openalex.org/W2171623668","https://openalex.org/W2172157844","https://openalex.org/W2245333323","https://openalex.org/W2312303239","https://openalex.org/W2318226053","https://openalex.org/W2320798307","https://openalex.org/W2327530675","https://openalex.org/W2331131021","https://openalex.org/W2334787351","https://openalex.org/W2335067603","https://openalex.org/W2391778664","https://openalex.org/W2404312388","https://openalex.org/W2406167887","https://openalex.org/W2408905673","https://openalex.org/W2412481666","https://openalex.org/W2482886635","https://openalex.org/W2798511792","https://openalex.org/W3148487900"],"related_works":["https://openalex.org/W2129524213","https://openalex.org/W1997282991","https://openalex.org/W2166712465","https://openalex.org/W2150639522","https://openalex.org/W2152541965","https://openalex.org/W2790564448","https://openalex.org/W2809400156","https://openalex.org/W2810599678","https://openalex.org/W7076628301","https://openalex.org/W2272661212"],"abstract_inverted_index":{"The":[0],"research":[1],"in":[2,28,58,65,164],"this":[3],"thesis":[4],"is":[5,170],"concerned":[6],"with":[7,43],"the":[8,181,186],"effect":[9],"of":[10,110,168,183],"chronic":[11,152,190,195],"stress,":[12],"caregiving":[13],"and":[14,16,20,36,63,68,90,115,126,129,143,160],"bereavement,":[15],"ageing":[17],"on":[18,158,185],"immune":[19,159,173],"endocrine":[21,161],"parameters.":[22],"First,":[23],"there":[24,54],"was":[25,55],"no":[26,56],"difference":[27,57],"serum":[29,78,127],"anti-CMV":[30],"antibody":[31,51],"titre":[32],"between":[33,61],"younger":[34,67,73],"caregivers":[35,42,62,74,85,98],"matched":[37],"controls,":[38,106,134],"but":[39,107,163],"CMV":[40,50],"seropositive":[41],"more":[44,100],"negative":[45],"health":[46],"behaviours":[47],"had":[48,93,99,139],"higher":[49,77,88,145],"titre.":[52],"Second,":[53],"neutrophil":[59,95,124,141],"function":[60,125,142],"controls":[64],"both":[66],"older":[69,136],"group,":[70],"while":[71],"only":[72],"showed":[75,122],"a":[76,144],"cortisol:cortisone":[79],"ratio":[80],"than":[81,105,193],"controls.":[82],"Further,":[83,178],"those":[84],"that":[86,151],"reported":[87],"anxiety":[89],"burden":[91],"symptoms":[92],"lower":[94],"phagocytosis.":[96],"Third,":[97],"senescent":[101],"KLRG1\\\\(^+\\\\)":[102],"T":[103,113],"cells":[104,114],"comparable":[108],"number":[109],"\u201cexhausted\u201d":[111],"PD-1\\\\(^+\\\\)":[112],"thymic":[116],"output.":[117],"Finally,":[118],"young":[119],"bereaved":[120,137],"adults":[121,138],"similar":[123],"cortisol":[128],"DHEAS":[130],"levels":[131],"as":[132],"non-bereaved":[133],"whereas":[135],"impaired":[140],"cortisol:DHEAS":[146],"ratio.":[147],"These":[148],"findings":[149],"suggest":[150],"stress":[153,191,196],"can":[154],"have":[155],"differential":[156],"effects":[157],"parameters,":[162],"some":[165],"cases,":[166],"presence":[167],"immunosenescence":[169],"required":[171],"for":[172],"decrements":[174],"to":[175,189],"be":[176],"observed.":[177],"they":[179],"emphasise":[180],"importance":[182],"focusing":[184],"individual's":[187],"response":[188],"rather":[192],"their":[194],"status,":[197],"per":[198],"se.":[199]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}