{"id":"https://openalex.org/W2997279876","doi":"https://doi.org/10.1016/j.carbpol.2019.115805","title":"Cyclodextrin-based delivery systems for chemotherapeutic anticancer drugs: A review","display_name":"Cyclodextrin-based delivery systems for chemotherapeutic anticancer drugs: A review","publication_year":2019,"publication_date":"2019-12-30","ids":{"openalex":"https://openalex.org/W2997279876","doi":"https://doi.org/10.1016/j.carbpol.2019.115805","mag":"2997279876","pmid":"https://pubmed.ncbi.nlm.nih.gov/31952603"},"language":"en","primary_location":{"id":"doi:10.1016/j.carbpol.2019.115805","doi":"https://doi.org/10.1016/j.carbpol.2019.115805","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.carbpol.2019.115805","pdf_url":null,"source":{"id":"https://openalex.org/S64311837","display_name":"Carbohydrate Polymers","issn_l":"0144-8617","issn":["0144-8617","1879-1344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carbohydrate Polymers","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076273431","display_name":"Bingren Tian","orcid":"https://orcid.org/0000-0001-9535-129X","observed_orcids":["https://orcid.org/0000-0001-9535-129X"]},"institutions":[{"id":"https://openalex.org/I96908189","display_name":"Xinjiang University","ror":"https://ror.org/059gw8r13","country_code":"CN","type":"education","lineage":["https://openalex.org/I96908189"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bingren Tian","raw_affiliation_strings":["College of Chemistry and Chemical Engineering, Xinjiang University, Urumchi 830001, China. Electronic address: tianbingren1@163.com","College of Chemistry and Chemical Engineering, Xinjiang University, Urumchi 830001, China"],"raw_orcid":"https://orcid.org/0000-0001-9535-129X","affiliations":[{"raw_affiliation_string":"College of Chemistry and Chemical Engineering, Xinjiang University, Urumchi 830001, China. Electronic address: tianbingren1@163.com","institution_ids":["https://openalex.org/I96908189"]},{"raw_affiliation_string":"College of Chemistry and Chemical Engineering, Xinjiang University, Urumchi 830001, China","institution_ids":["https://openalex.org/I96908189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030561058","display_name":"Shiyao Hua","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127460","display_name":"Ningxia Medical University","ror":"https://ror.org/02h8a1848","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210127460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shiyao Hua","raw_affiliation_strings":["School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China","institution_ids":["https://openalex.org/I4210127460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063000042","display_name":"Jiayue Liu","orcid":"https://orcid.org/0000-0003-0853-8158","observed_orcids":["https://orcid.org/0000-0003-0853-8158","https://orcid.org/0009-0001-4777-0948"]},"institutions":[{"id":"https://openalex.org/I4210127460","display_name":"Ningxia Medical University","ror":"https://ror.org/02h8a1848","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210127460"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jiayue Liu","raw_affiliation_strings":["School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China. Electronic address: 15809513327@163.com","School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China. Electronic address: 15809513327@163.com","institution_ids":["https://openalex.org/I4210127460"]},{"raw_affiliation_string":"School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China","institution_ids":["https://openalex.org/I4210127460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5063000042","https://openalex.org/A5076273431"],"corresponding_institution_ids":["https://openalex.org/I4210127460","https://openalex.org/I96908189"],"apc_list":{"value":3150,"currency":"USD","value_usd":3150},"apc_paid":null,"fwci":2.4862,"has_fulltext":false,"cited_by_count":217,"citation_normalized_percentile":{"value":0.92821782,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"232","issue":null,"first_page":"115805","last_page":"115805"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.5746999979019165,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.5746999979019165,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.301800012588501,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.035999998450279236,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclodextrins","display_name":"cyclodextrins","score":0.9959999918937683},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.7739999890327454},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.8429999947547913},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.9570000171661377},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.8629999756813049},{"id":"https://openalex.org/keywords/cyclic-oligosaccharides","display_name":"cyclic oligosaccharides","score":0.8650000095367432},{"id":"https://openalex.org/keywords/controlled-drug-release","display_name":"controlled drug release","score":0.7509999871253967},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.8209999799728394}],"concepts":[{"id":"https://openalex.org/C2779433975","wikidata":"https://www.wikidata.org/wiki/Q40417805","display_name":"Cyclodextrin","level":2,"score":0.6653948426246643},{"id":"https://openalex.org/C15083742","wikidata":"https://www.wikidata.org/wiki/Q261659","display_name":"Nanomedicine","level":3,"score":0.6474584937095642},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6104262471199036},{"id":"https://openalex.org/C2983331546","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer therapy","level":3,"score":0.5877367854118347},{"id":"https://openalex.org/C2983288658","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Cancer chemotherapy","level":3,"score":0.5149955749511719},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5116565823554993},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.48672154545783997},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.46197497844696045},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.44863033294677734},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44531869888305664},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.44096291065216064},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3563488721847534},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.21128806471824646},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.13740533590316772},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11054122447967529},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10535725951194763},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002236","descriptor_name":"Carbohydrate Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003505","descriptor_name":"Cyclodextrins","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D003505","descriptor_name":"Cyclodextrins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004337","descriptor_name":"Drug Carriers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.carbpol.2019.115805","doi":"https://doi.org/10.1016/j.carbpol.2019.115805","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.carbpol.2019.115805","pdf_url":null,"source":{"id":"https://openalex.org/S64311837","display_name":"Carbohydrate Polymers","issn_l":"0144-8617","issn":["0144-8617","1879-1344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carbohydrate Polymers","raw_type":"journal-article"},{"id":"pmid:31952603","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31952603","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carbohydrate polymers","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":184,"referenced_works":["https://openalex.org/W404871011","https://openalex.org/W966190883","https://openalex.org/W1008645380","https://openalex.org/W1526426530","https://openalex.org/W1527337061","https://openalex.org/W1602132035","https://openalex.org/W1799521169","https://openalex.org/W1886944491","https://openalex.org/W1956632466","https://openalex.org/W1965122895","https://openalex.org/W1969611580","https://openalex.org/W1973249462","https://openalex.org/W1973803162","https://openalex.org/W1975071040","https://openalex.org/W1986947324","https://openalex.org/W1987496016","https://openalex.org/W1989758373","https://openalex.org/W1992248096","https://openalex.org/W1992971278","https://openalex.org/W1995777090","https://openalex.org/W1996430068","https://openalex.org/W1998663218","https://openalex.org/W2001570423","https://openalex.org/W2004141662","https://openalex.org/W2004918315","https://openalex.org/W2005337990","https://openalex.org/W2008033906","https://openalex.org/W2010567530","https://openalex.org/W2014509855","https://openalex.org/W2015700471","https://openalex.org/W2016806712","https://openalex.org/W2017916544","https://openalex.org/W2023053801","https://openalex.org/W2023966266","https://openalex.org/W2025128766","https://openalex.org/W2026461087","https://openalex.org/W2031281559","https://openalex.org/W2032382272","https://openalex.org/W2037096170","https://openalex.org/W2039092501","https://openalex.org/W2039322892","https://openalex.org/W2040226141","https://openalex.org/W2044520517","https://openalex.org/W2048125425","https://openalex.org/W2050031865","https://openalex.org/W2050672682","https://openalex.org/W2052192061","https://openalex.org/W2055205288","https://openalex.org/W2058575034","https://openalex.org/W2062329303","https://openalex.org/W2062366721","https://openalex.org/W2065458286","https://openalex.org/W2066236577","https://openalex.org/W2067412818","https://openalex.org/W2073318027","https://openalex.org/W2073509432","https://openalex.org/W2074245988","https://openalex.org/W2074892026","https://openalex.org/W2075261158","https://openalex.org/W2082669639","https://openalex.org/W2083811444","https://openalex.org/W2091654446","https://openalex.org/W2105948373","https://openalex.org/W2110371858","https://openalex.org/W2113959224","https://openalex.org/W2121805411","https://openalex.org/W2122489231","https://openalex.org/W2126596404","https://openalex.org/W2127242272","https://openalex.org/W2129039800","https://openalex.org/W2130458476","https://openalex.org/W2137969025","https://openalex.org/W2140093304","https://openalex.org/W2142553680","https://openalex.org/W2142586537","https://openalex.org/W2144389574","https://openalex.org/W2145200068","https://openalex.org/W2149107062","https://openalex.org/W2151390784","https://openalex.org/W2152434506","https://openalex.org/W2158155063","https://openalex.org/W2163276935","https://openalex.org/W2165864530","https://openalex.org/W2206155187","https://openalex.org/W2218846395","https://openalex.org/W2220972534","https://openalex.org/W2239461891","https://openalex.org/W2270096887","https://openalex.org/W2270129087","https://openalex.org/W2284554783","https://openalex.org/W2314075508","https://openalex.org/W2326287562","https://openalex.org/W2335361678","https://openalex.org/W2338569033","https://openalex.org/W2401122991","https://openalex.org/W2413607402","https://openalex.org/W2440944183","https://openalex.org/W2466093998","https://openalex.org/W2467030378","https://openalex.org/W2475807018","https://openalex.org/W2522873012","https://openalex.org/W2528333084","https://openalex.org/W2538961279","https://openalex.org/W2555415714","https://openalex.org/W2569116361","https://openalex.org/W2578915687","https://openalex.org/W2596033236","https://openalex.org/W2597015436","https://openalex.org/W2610816916","https://openalex.org/W2623905060","https://openalex.org/W2742261361","https://openalex.org/W2751686332","https://openalex.org/W2754508804","https://openalex.org/W2760001746","https://openalex.org/W2763418785","https://openalex.org/W2765607055","https://openalex.org/W2776006452","https://openalex.org/W2780626714","https://openalex.org/W2787178433","https://openalex.org/W2787820664","https://openalex.org/W2789803429","https://openalex.org/W2790918260","https://openalex.org/W2791483720","https://openalex.org/W2792588868","https://openalex.org/W2794342804","https://openalex.org/W2794592020","https://openalex.org/W2795755769","https://openalex.org/W2799602777","https://openalex.org/W2805041351","https://openalex.org/W2809184797","https://openalex.org/W2852075290","https://openalex.org/W2884065986","https://openalex.org/W2884184097","https://openalex.org/W2885375398","https://openalex.org/W2889646458","https://openalex.org/W2890107585","https://openalex.org/W2891589486","https://openalex.org/W2892565790","https://openalex.org/W2893814803","https://openalex.org/W2895258691","https://openalex.org/W2895365999","https://openalex.org/W2896945901","https://openalex.org/W2897213991","https://openalex.org/W2897713833","https://openalex.org/W2898119015","https://openalex.org/W2898440246","https://openalex.org/W2900326015","https://openalex.org/W2900474459","https://openalex.org/W2900960501","https://openalex.org/W2901219763","https://openalex.org/W2901612335","https://openalex.org/W2904289456","https://openalex.org/W2906755756","https://openalex.org/W2908291702","https://openalex.org/W2909085453","https://openalex.org/W2911597577","https://openalex.org/W2911650004","https://openalex.org/W2911805989","https://openalex.org/W2912753775","https://openalex.org/W2913625442","https://openalex.org/W2915327709","https://openalex.org/W2916077054","https://openalex.org/W2918664189","https://openalex.org/W2921393408","https://openalex.org/W2921956688","https://openalex.org/W2922677177","https://openalex.org/W2923344116","https://openalex.org/W2935430861","https://openalex.org/W2942364502","https://openalex.org/W2943586512","https://openalex.org/W2943626573","https://openalex.org/W2943896712","https://openalex.org/W2945861018","https://openalex.org/W2948992643","https://openalex.org/W2949415270","https://openalex.org/W2952575846","https://openalex.org/W2971398989","https://openalex.org/W2983048398","https://openalex.org/W3090777642","https://openalex.org/W4211053799","https://openalex.org/W4235430805","https://openalex.org/W4238065816","https://openalex.org/W4243323400","https://openalex.org/W6754669450"],"related_works":["https://openalex.org/W4292686240","https://openalex.org/W4409993999","https://openalex.org/W4392571121","https://openalex.org/W4324093173","https://openalex.org/W4409534920","https://openalex.org/W3026425601","https://openalex.org/W2809184797","https://openalex.org/W2754508804","https://openalex.org/W4296117241","https://openalex.org/W2971691151"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":17},{"year":2025,"cited_by_count":32},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":38},{"year":2022,"cited_by_count":32},{"year":2021,"cited_by_count":43},{"year":2020,"cited_by_count":31}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-01-10T00:00:00"}