{"id":"https://openalex.org/W2997274320","doi":"https://doi.org/10.1016/j.biomaterials.2019.119739","title":"Substrate curvature as a cue to guide spatiotemporal cell and tissue organization","display_name":"Substrate curvature as a cue to guide spatiotemporal cell and tissue organization","publication_year":2019,"publication_date":"2019-12-27","ids":{"openalex":"https://openalex.org/W2997274320","doi":"https://doi.org/10.1016/j.biomaterials.2019.119739","mag":"2997274320","pmid":"https://pubmed.ncbi.nlm.nih.gov/31911284"},"language":"en","primary_location":{"id":"doi:10.1016/j.biomaterials.2019.119739","doi":"https://doi.org/10.1016/j.biomaterials.2019.119739","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2019.119739","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0142961219308579/pdf","source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2997274320"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0142961219308579/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017893181","display_name":"Sebastien J. P. Callens","orcid":"https://orcid.org/0000-0002-0179-4098","observed_orcids":["https://orcid.org/0000-0002-0179-4098"]},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Sebastien J.P. Callens","raw_affiliation_strings":["Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands. Electronic address: s.j.p.callens@tudelft.nl","Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands. Electronic address: s.j.p.callens@tudelft.nl","institution_ids":["https://openalex.org/I98358874"]},{"raw_affiliation_string":"Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands","institution_ids":["https://openalex.org/I98358874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001976678","display_name":"Rafael J.C. Uyttendaele","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Rafael J.C. Uyttendaele","raw_affiliation_strings":["Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands","institution_ids":["https://openalex.org/I98358874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074766156","display_name":"Lidy Elena Fratila-Apachitei","orcid":"https://orcid.org/0000-0002-7341-4445","observed_orcids":["https://orcid.org/0000-0002-7341-4445"]},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Lidy E. Fratila-Apachitei","raw_affiliation_strings":["Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands","institution_ids":["https://openalex.org/I98358874"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085851098","display_name":"AMIR ABBAS ZADPOOR","orcid":"https://orcid.org/0000-0003-3234-2112","observed_orcids":["https://orcid.org/0000-0003-3234-2112"]},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Amir A. Zadpoor","raw_affiliation_strings":["Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628CD, the Netherlands","institution_ids":["https://openalex.org/I98358874"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5017893181"],"corresponding_institution_ids":["https://openalex.org/I98358874"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":{"value":3900,"currency":"USD","value_usd":3900},"fwci":2.5636,"has_fulltext":true,"cited_by_count":331,"citation_normalized_percentile":{"value":0.92997925,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"232","issue":null,"first_page":"119739","last_page":"119739"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11737","display_name":"Advanced Materials and Mechanics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/substrate-curvature","display_name":"substrate curvature","score":0.9639999866485596},{"id":"https://openalex.org/keywords/mean-curvature","display_name":"mean curvature","score":0.6669999957084656},{"id":"https://openalex.org/keywords/gaussian-curvature","display_name":"Gaussian curvature","score":1.0},{"id":"https://openalex.org/keywords/cell-mechanics","display_name":"cell mechanics","score":0.39899998903274536},{"id":"https://openalex.org/keywords/tissue-morphogenesis","display_name":"tissue morphogenesis","score":0.9269999861717224},{"id":"https://openalex.org/keywords/tensile-force","display_name":"tensile force","score":0.7429999709129333},{"id":"https://openalex.org/keywords/curvature-flow","display_name":"curvature flow","score":0.8769999742507935},{"id":"https://openalex.org/keywords/scaffold-design","display_name":"scaffold design","score":0.7049999833106995},{"id":"https://openalex.org/keywords/tissue-regeneration","display_name":"tissue regeneration","score":0.9070000052452087}],"concepts":[{"id":"https://openalex.org/C195065555","wikidata":"https://www.wikidata.org/wiki/Q214881","display_name":"Curvature","level":2,"score":0.867620587348938},{"id":"https://openalex.org/C16140857","wikidata":"https://www.wikidata.org/wiki/Q945953","display_name":"Gaussian curvature","level":3,"score":0.7866154909133911},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.6089404225349426},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4412890076637268},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.4403139054775238},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.43030866980552673},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.42821308970451355},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.33845412731170654},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3285134434700012},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3219149112701416},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31716102361679077},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23531612753868103},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.2298828661441803},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.15730643272399902},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.15462949872016907},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003463","descriptor_name":"Cues","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.biomaterials.2019.119739","doi":"https://doi.org/10.1016/j.biomaterials.2019.119739","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2019.119739","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0142961219308579/pdf","source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},{"id":"pmid:31911284","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31911284","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"Journal Article"},{"id":"pmh:oai:tudelft.nl:uuid:020838d9-c8bb-4521-bf13-2974dc85cb92","doi":null,"is_oa":false,"landing_page_url":"http://resolver.tudelft.nl/uuid:020838d9-c8bb-4521-bf13-2974dc85cb92","pdf_url":null,"source":{"id":"https://openalex.org/S4306400906","display_name":"Research Repository (Delft University of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98358874","host_organization_name":"Delft University of Technology","host_organization_lineage":["https://openalex.org/I98358874"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"review"},{"id":"pmh:tud:oai:tudelft.nl:uuid:020838d9-c8bb-4521-bf13-2974dc85cb92","doi":null,"is_oa":true,"landing_page_url":"http://resolver.tudelft.nl/uuid:020838d9-c8bb-4521-bf13-2974dc85cb92","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biomaterials, 232","raw_type":"info:eu-repo/semantics/review"}],"best_oa_location":{"id":"doi:10.1016/j.biomaterials.2019.119739","doi":"https://doi.org/10.1016/j.biomaterials.2019.119739","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2019.119739","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0142961219308579/pdf","source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4486107811","display_name":"Meta-biomaterials: 3D printing meets Origami","funder_award_id":"677575","funder_id":"https://openalex.org/F4320338335","funder_display_name":"H2020 European Research Council"},{"id":"https://openalex.org/G816295934","display_name":null,"funder_award_id":"677575","funder_id":"https://openalex.org/F4320334678","funder_display_name":"European Research Council"}],"funders":[{"id":"https://openalex.org/F4320334678","display_name":"European Research Council","ror":"https://ror.org/0472cxd90"},{"id":"https://openalex.org/F4320338335","display_name":"H2020 European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2997274320.pdf","grobid_xml":"https://content.openalex.org/works/W2997274320.grobid-xml"},"referenced_works_count":210,"referenced_works":["https://openalex.org/W56502103","https://openalex.org/W221386278","https://openalex.org/W578453537","https://openalex.org/W1175618232","https://openalex.org/W1225109155","https://openalex.org/W1238092070","https://openalex.org/W1509346826","https://openalex.org/W1533058090","https://openalex.org/W1568151868","https://openalex.org/W1587940648","https://openalex.org/W1596838913","https://openalex.org/W1625630534","https://openalex.org/W1902552143","https://openalex.org/W1904984953","https://openalex.org/W1907649404","https://openalex.org/W1923303716","https://openalex.org/W1963739427","https://openalex.org/W1964081206","https://openalex.org/W1965677814","https://openalex.org/W1965933207","https://openalex.org/W1966277980","https://openalex.org/W1967240031","https://openalex.org/W1967265143","https://openalex.org/W1970570245","https://openalex.org/W1971224801","https://openalex.org/W1974684276","https://openalex.org/W1975703565","https://openalex.org/W1975781184","https://openalex.org/W1976400946","https://openalex.org/W1976925230","https://openalex.org/W1977883728","https://openalex.org/W1979366429","https://openalex.org/W1979883641","https://openalex.org/W1980632659","https://openalex.org/W1981332112","https://openalex.org/W1981450485","https://openalex.org/W1985763935","https://openalex.org/W1985847842","https://openalex.org/W1990914175","https://openalex.org/W1994076220","https://openalex.org/W1994653877","https://openalex.org/W1996187477","https://openalex.org/W1997351324","https://openalex.org/W1998634625","https://openalex.org/W2002223490","https://openalex.org/W2003315801","https://openalex.org/W2003706739","https://openalex.org/W2003986773","https://openalex.org/W2005200966","https://openalex.org/W2007483105","https://openalex.org/W2007660746","https://openalex.org/W2008277897","https://openalex.org/W2013002334","https://openalex.org/W2015094353","https://openalex.org/W2019731805","https://openalex.org/W2019841520","https://openalex.org/W2023026872","https://openalex.org/W2025522134","https://openalex.org/W2027099814","https://openalex.org/W2028013007","https://openalex.org/W2028376002","https://openalex.org/W2029253255","https://openalex.org/W2029392940","https://openalex.org/W2029991360","https://openalex.org/W2030029307","https://openalex.org/W2030041577","https://openalex.org/W2033108841","https://openalex.org/W2033637395","https://openalex.org/W2039879435","https://openalex.org/W2040379229","https://openalex.org/W2045429993","https://openalex.org/W2046576188","https://openalex.org/W2047997264","https://openalex.org/W2049542013","https://openalex.org/W2052373675","https://openalex.org/W2052400143","https://openalex.org/W2054635074","https://openalex.org/W2056258594","https://openalex.org/W2057564766","https://openalex.org/W2060250773","https://openalex.org/W2061465719","https://openalex.org/W2062582615","https://openalex.org/W2063220206","https://openalex.org/W2063810183","https://openalex.org/W2070779511","https://openalex.org/W2071145526","https://openalex.org/W2072167784","https://openalex.org/W2072591884","https://openalex.org/W2075755310","https://openalex.org/W2077134765","https://openalex.org/W2078326572","https://openalex.org/W2081128785","https://openalex.org/W2082225658","https://openalex.org/W2085124299","https://openalex.org/W2090410789","https://openalex.org/W2094098398","https://openalex.org/W2097970956","https://openalex.org/W2098373224","https://openalex.org/W2100983000","https://openalex.org/W2101601223","https://openalex.org/W2102661335","https://openalex.org/W2103076822","https://openalex.org/W2105503408","https://openalex.org/W2108586733","https://openalex.org/W2109137926","https://openalex.org/W2112729030","https://openalex.org/W2119708685","https://openalex.org/W2120559167","https://openalex.org/W2123741193","https://openalex.org/W2125170987","https://openalex.org/W2125644189","https://openalex.org/W2126087366","https://openalex.org/W2132375258","https://openalex.org/W2132917470","https://openalex.org/W2133065239","https://openalex.org/W2134208433","https://openalex.org/W2134326799","https://openalex.org/W2137028393","https://openalex.org/W2137034111","https://openalex.org/W2137452172","https://openalex.org/W2138294521","https://openalex.org/W2138371284","https://openalex.org/W2140729981","https://openalex.org/W2144023435","https://openalex.org/W2145468853","https://openalex.org/W2146371952","https://openalex.org/W2150693489","https://openalex.org/W2151019600","https://openalex.org/W2151492748","https://openalex.org/W2151517067","https://openalex.org/W2161672145","https://openalex.org/W2163504716","https://openalex.org/W2165707177","https://openalex.org/W2169148364","https://openalex.org/W2170692131","https://openalex.org/W2171577674","https://openalex.org/W2181440869","https://openalex.org/W2182880583","https://openalex.org/W2185806365","https://openalex.org/W2225115505","https://openalex.org/W2266720690","https://openalex.org/W2270498673","https://openalex.org/W2291613060","https://openalex.org/W2317835385","https://openalex.org/W2320821933","https://openalex.org/W2326721495","https://openalex.org/W2398302729","https://openalex.org/W2401482619","https://openalex.org/W2408382340","https://openalex.org/W2410195985","https://openalex.org/W2411841803","https://openalex.org/W2511255813","https://openalex.org/W2517314340","https://openalex.org/W2521227613","https://openalex.org/W2522385569","https://openalex.org/W2530379722","https://openalex.org/W2560807219","https://openalex.org/W2562843154","https://openalex.org/W2568733274","https://openalex.org/W2588363712","https://openalex.org/W2589346240","https://openalex.org/W2590915628","https://openalex.org/W2605843673","https://openalex.org/W2620545979","https://openalex.org/W2621590149","https://openalex.org/W2625847289","https://openalex.org/W2686900739","https://openalex.org/W2725412839","https://openalex.org/W2737551321","https://openalex.org/W2738008305","https://openalex.org/W2753650690","https://openalex.org/W2765479093","https://openalex.org/W2765924074","https://openalex.org/W2767369251","https://openalex.org/W2767824561","https://openalex.org/W2769197062","https://openalex.org/W2770901135","https://openalex.org/W2775339123","https://openalex.org/W2775910750","https://openalex.org/W2779507783","https://openalex.org/W2784479902","https://openalex.org/W2785110060","https://openalex.org/W2792550994","https://openalex.org/W2794620576","https://openalex.org/W2798110095","https://openalex.org/W2802309935","https://openalex.org/W2805504863","https://openalex.org/W2806867359","https://openalex.org/W2838830137","https://openalex.org/W2884167071","https://openalex.org/W2886907493","https://openalex.org/W2889062661","https://openalex.org/W2889728237","https://openalex.org/W2892459790","https://openalex.org/W2893419411","https://openalex.org/W2895707213","https://openalex.org/W2896798182","https://openalex.org/W2903196097","https://openalex.org/W2904050503","https://openalex.org/W2911973964","https://openalex.org/W2914598451","https://openalex.org/W2921241224","https://openalex.org/W2932038493","https://openalex.org/W2943941736","https://openalex.org/W2950649811","https://openalex.org/W2970650976","https://openalex.org/W2971447314","https://openalex.org/W2973183603","https://openalex.org/W4210961155","https://openalex.org/W6646823773"],"related_works":["https://openalex.org/W2625847289","https://openalex.org/W7167515990","https://openalex.org/W4323042834","https://openalex.org/W7204629036","https://openalex.org/W4413020055","https://openalex.org/W3135670807","https://openalex.org/W2921241224","https://openalex.org/W2125170987","https://openalex.org/W7130396475"],"abstract_inverted_index":{"Recent":[0],"evidence":[1,78,125],"clearly":[2],"shows":[3],"that":[4,26,80,149,159],"cells":[5,88],"respond":[6],"to":[7,52,173],"various":[8],"physical":[9],"cues":[10],"in":[11,93,101],"their":[12],"environments,":[13],"guiding":[14],"many":[15],"cellular":[16],"processes":[17],"and":[18,22,46,56,60,73,89,118,121,132,146],"tissue":[19,47,58,133,176,188],"morphogenesis,":[20],"pathology,":[21],"repair.":[23],"One":[24],"aspect":[25],"is":[27,31,70],"gaining":[28],"significant":[29],"traction":[30],"the":[32,63,84,114,123,130,137,141,151,190],"role":[33],"of":[34,67,77,87,116,153,168],"local":[35,68],"geometry":[36,43,69],"as":[37],"an":[38],"extracellular":[39],"cue.":[40],"Elucidating":[41],"how":[42],"affects":[44,83],"cell":[45,131],"behavior":[48],"is,":[49],"indeed,":[50],"crucial":[51],"design":[53,195],"artificial":[54],"scaffolds":[55],"understand":[57],"growth":[59,177],"remodeling.":[61],"Perhaps":[62],"most":[64],"fundamental":[65],"descriptor":[66],"surface":[71,81],"curvature,":[72,120],"a":[74,107],"growing":[75],"body":[76],"confirms":[79],"curvature":[82,96,110,127,148,154,169,181],"spatiotemporal":[85],"organization":[86],"tissues.":[90],"While":[91],"well-defined":[92],"differential":[94],"geometry,":[95],"remains":[97],"somewhat":[98],"ambiguously":[99],"treated":[100],"biological":[102],"studies.":[103],"Here,":[104],"we":[105,157],"provide":[106],"more":[108],"formal":[109],"framework,":[111],"based":[112,164],"on":[113,126,165,201],"notions":[115],"mean":[117],"Gaussian":[119],"summarize":[122],"available":[124],"guidance":[128,182],"at":[129],"levels.":[134],"We":[135],"discuss":[136],"involved":[138],"mechanisms,":[139],"highlighting":[140],"interplay":[142],"between":[143],"tensile":[144],"forces":[145],"substrate":[147],"forms":[150],"foundation":[152],"guidance.":[155],"Moreover,":[156],"show":[158],"relatively":[160],"simple":[161],"computational":[162],"models,":[163],"some":[166],"application":[167],"flow,":[170],"are":[171,196,205],"able":[172],"capture":[174],"experimental":[175],"remarkably":[178],"well.":[179],"Since":[180],"principles":[183],"could":[184],"be":[185],"leveraged":[186],"for":[187,192],"regeneration,":[189],"implications":[191],"geometrical":[193],"scaffold":[194],"also":[197],"discussed.":[198],"Finally,":[199],"perspectives":[200],"future":[202],"research":[203],"opportunities":[204],"provided.":[206]},"counts_by_year":[{"year":2026,"cited_by_count":44},{"year":2025,"cited_by_count":55},{"year":2024,"cited_by_count":52},{"year":2023,"cited_by_count":66},{"year":2022,"cited_by_count":50},{"year":2021,"cited_by_count":41},{"year":2020,"cited_by_count":23}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2020-01-10T00:00:00"}
