{"id":"https://openalex.org/W2996562996","doi":null,"title":"Preparation of Folic Acid-Carbon Dots-Doxorubicin Nanoparticles as Targeting Tumor Theranostics","display_name":"Preparation of Folic Acid-Carbon Dots-Doxorubicin Nanoparticles as Targeting Tumor Theranostics","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2996562996","mag":"2996562996"},"language":"en","primary_location":{"id":"pmh:oai:dc.etsu.edu:etd-5149","doi":null,"is_oa":true,"landing_page_url":"https://dc.etsu.edu/etd/3671","pdf_url":"https://dc.etsu.edu/cgi/viewcontent.cgi?article=5149&context=etd","source":{"id":"https://openalex.org/S4377196424","display_name":"Digital Commons - East Tennessee State University (East Tennessee State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I119443389","host_organization_name":"East Tennessee State University","host_organization_lineage":["https://openalex.org/I119443389"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Theses and Dissertations","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://dc.etsu.edu/cgi/viewcontent.cgi?article=5149&context=etd","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003448290","display_name":"Samson Niyi Dada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Samson Niyi Dada","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5003448290"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0848,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.29255425,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11342","display_name":"Carbon and Quantum Dots Applications","score":0.45019999146461487,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11342","display_name":"Carbon and Quantum Dots Applications","score":0.45019999146461487,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.28439998626708984,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.24889999628067017,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbon-dots","display_name":"carbon dots","score":0.9950000047683716},{"id":"https://openalex.org/keywords/folic-acid","display_name":"folic acid","score":0.9079999923706055},{"id":"https://openalex.org/keywords/doxorubicin","display_name":"doxorubicin","score":1.0},{"id":"https://openalex.org/keywords/nanoparticles","display_name":"nanoparticles","score":0.6150000095367432},{"id":"https://openalex.org/keywords/tumor-targeting","display_name":"tumor targeting","score":0.6549999713897705},{"id":"https://openalex.org/keywords/theranostics","display_name":"theranostics","score":0.9639999866485596},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.9649999737739563},{"id":"https://openalex.org/keywords/drug-loading-capacity","display_name":"drug loading capacity","score":0.7630000114440918},{"id":"https://openalex.org/keywords/drug-release","display_name":"drug release","score":0.7649999856948853},{"id":"https://openalex.org/keywords/fluorescence-imaging","display_name":"fluorescence imaging","score":0.6520000100135803},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.3619999885559082}],"concepts":[{"id":"https://openalex.org/C2992130864","wikidata":"https://www.wikidata.org/wiki/Q127060","display_name":"Folic acid","level":2,"score":0.7474958896636963},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.6474323272705078},{"id":"https://openalex.org/C2781303535","wikidata":"https://www.wikidata.org/wiki/Q18936","display_name":"Doxorubicin","level":3,"score":0.6236394643783569},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4853035807609558},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40794801712036133},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2957437336444855},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2769467532634735},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13089033961296082},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.12815141677856445}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:dc.etsu.edu:etd-5149","doi":null,"is_oa":true,"landing_page_url":"https://dc.etsu.edu/etd/3671","pdf_url":"https://dc.etsu.edu/cgi/viewcontent.cgi?article=5149&context=etd","source":{"id":"https://openalex.org/S4377196424","display_name":"Digital Commons - East Tennessee State University (East Tennessee State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I119443389","host_organization_name":"East Tennessee State University","host_organization_lineage":["https://openalex.org/I119443389"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Theses and Dissertations","raw_type":"text"},{"id":"mag:2996562996","doi":null,"is_oa":false,"landing_page_url":"https://dc.etsu.edu/etd/3671/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:dc.etsu.edu:etd-5149","doi":null,"is_oa":true,"landing_page_url":"https://dc.etsu.edu/etd/3671","pdf_url":"https://dc.etsu.edu/cgi/viewcontent.cgi?article=5149&context=etd","source":{"id":"https://openalex.org/S4377196424","display_name":"Digital Commons - East Tennessee State University (East Tennessee State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I119443389","host_organization_name":"East Tennessee State University","host_organization_lineage":["https://openalex.org/I119443389"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Theses and Dissertations","raw_type":"text"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2996562996.pdf","grobid_xml":"https://content.openalex.org/works/W2996562996.grobid-xml"},"referenced_works_count":77,"referenced_works":["https://openalex.org/W1507264290","https://openalex.org/W1674207895","https://openalex.org/W1859634969","https://openalex.org/W1903819079","https://openalex.org/W1963754854","https://openalex.org/W1969663610","https://openalex.org/W1970290419","https://openalex.org/W1971837812","https://openalex.org/W1972960507","https://openalex.org/W1973108158","https://openalex.org/W1986568717","https://openalex.org/W1987702782","https://openalex.org/W1996672400","https://openalex.org/W1997437932","https://openalex.org/W2000205238","https://openalex.org/W2008400200","https://openalex.org/W2009341507","https://openalex.org/W2013991836","https://openalex.org/W2021635812","https://openalex.org/W2025669689","https://openalex.org/W2026273139","https://openalex.org/W2036636678","https://openalex.org/W2037193648","https://openalex.org/W2038980827","https://openalex.org/W2047816702","https://openalex.org/W2054190165","https://openalex.org/W2058525339","https://openalex.org/W2062485439","https://openalex.org/W2063672659","https://openalex.org/W2067848116","https://openalex.org/W2090240174","https://openalex.org/W2090249020","https://openalex.org/W2094437628","https://openalex.org/W2121157561","https://openalex.org/W2122071242","https://openalex.org/W2130652864","https://openalex.org/W2132635365","https://openalex.org/W2133127259","https://openalex.org/W2134125286","https://openalex.org/W2140486739","https://openalex.org/W2148055851","https://openalex.org/W2152934987","https://openalex.org/W2154321074","https://openalex.org/W2154738003","https://openalex.org/W2157770632","https://openalex.org/W2158734599","https://openalex.org/W2162689981","https://openalex.org/W2169336018","https://openalex.org/W2259769481","https://openalex.org/W2259979288","https://openalex.org/W2273847496","https://openalex.org/W2275098614","https://openalex.org/W2313621674","https://openalex.org/W2327814051","https://openalex.org/W2349584256","https://openalex.org/W2491458126","https://openalex.org/W2517072728","https://openalex.org/W2521808167","https://openalex.org/W2531506441","https://openalex.org/W2561697749","https://openalex.org/W2568527314","https://openalex.org/W2576285435","https://openalex.org/W2588278653","https://openalex.org/W2594395525","https://openalex.org/W2624465932","https://openalex.org/W2734781575","https://openalex.org/W2751852570","https://openalex.org/W2783404219","https://openalex.org/W2785949980","https://openalex.org/W2790960066","https://openalex.org/W2800858073","https://openalex.org/W2885001542","https://openalex.org/W2905700682","https://openalex.org/W2913339275","https://openalex.org/W2915290859","https://openalex.org/W2936404809","https://openalex.org/W2936432777"],"related_works":["https://openalex.org/W6981826191","https://openalex.org/W4283391355","https://openalex.org/W6996988561","https://openalex.org/W7065958392","https://openalex.org/W2943040253","https://openalex.org/W3091904397","https://openalex.org/W7112320701","https://openalex.org/W4289338329","https://openalex.org/W1987702782","https://openalex.org/W3155492286"],"abstract_inverted_index":{"Carbon":[0],"dots":[1],"(CDs)":[2,34],"have":[3],"attracted":[4],"much":[5],"attention":[6],"as":[7],"an":[8],"excellent":[9],"gene/drug":[10],"delivery":[11],"and":[12,42,51,62,72,98],"biological":[13],"imaging":[14],"agent":[15,45],"for":[16],"early":[17],"cancer":[18],"theranostics.":[19],"In":[20,106],"this":[21],"study,":[22],"we":[23],"prepared":[24],"two":[25,78],"series":[26,79],"of":[27,33,77,80,91,112,124],"nanoparticles":[28],"(NPs),":[29],"which":[30],"are":[31],"composed":[32],"with":[35],"a":[36,43,121],"targeting":[37],"agent,":[38],"folic":[39],"acid":[40],"(FA),":[41],"chemotherapeutic":[44],"Doxorubicin":[46],"(Dox).":[47],"All":[48],"the":[49,89,108,115],"NPs":[50],"their":[52],"intermediates":[53],"were":[54,82,118],"characterized":[55],"using":[56,84],"ultraviolet-visible":[57],"spectroscopy":[58,65,87],"(UV-vis),":[59],"fluorescence":[60],"spectroscopy,":[61],"Fourier":[63],"transform-infrared":[64],"(FT-IR).":[66],"The":[67],"drug":[68,73],"loading":[69,74],"capacity":[70],"(DLC)":[71],"efficiency":[75],"(DLE)":[76],"FA-CDs-Dox":[81,116],"assessed":[83],"UV-vis":[85],"absorption":[86],"at":[88],"wavelength":[90],"485":[92],"nm.":[93],"Both":[94],"showed":[95],"good":[96],"DLE":[97],"DLC":[99],"results":[100],"when":[101],"compared":[102],"to":[103],"literature":[104],"data.":[105],"addition,":[107],"cumulative":[109],"release":[110],"property":[111],"Dox":[113],"from":[114],"complexes":[117],"investigated":[119],"in":[120],"pH":[122],"solution":[123],"7.4.":[125]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-12-26T00:00:00"}