{"id":"https://openalex.org/W2995647250","doi":null,"title":"Oral tranexamic acid associated with platelet transfusion to prevent hemorrhage in a patient with Glanzmann thrombasthenia.","display_name":"Oral tranexamic acid associated with platelet transfusion to prevent hemorrhage in a patient with Glanzmann thrombasthenia.","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2995647250","mag":"2995647250","pmid":"https://pubmed.ncbi.nlm.nih.gov/30644834"},"language":"en","primary_location":{"id":"pmid:30644834","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30644834","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General dentistry","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027811663","display_name":"Luan Cartaxo F\u00e9lix","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luan Cartaxo F\u00e9lix","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014861545","display_name":"Madiana Magalh\u00e3es Moreira","orcid":"https://orcid.org/0000-0002-2753-0189","observed_orcids":["https://orcid.org/0000-0002-2753-0189"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Madiana Magalh\u00e3es Moreira","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035720915","display_name":"Francisco Artur Forte Oliveira","orcid":"https://orcid.org/0000-0002-6913-3261","observed_orcids":["https://orcid.org/0000-0002-6913-3261"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francisco Artur Forte Oliveira","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085507994","display_name":"Clarissa Pessoa Fernandes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Clarissa Pessoa Fernandes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030861045","display_name":"M\u00e1rio Rog\u00e9rio Lima Mota","orcid":"https://orcid.org/0000-0003-3778-0584","observed_orcids":["https://orcid.org/0000-0003-3778-0584"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mario Rog\u00e9rio Lima Mota","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100603121","display_name":"Ana Paula Negreiros Nunes Alves","orcid":"https://orcid.org/0000-0002-5090-6877","observed_orcids":["https://orcid.org/0000-0002-5090-6877"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ana Paula Negreiros Nunes Alves","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5012881347","display_name":"Fabr\u00edcio Bit\u00fa Sousa","orcid":"https://orcid.org/0000-0002-6430-9475","observed_orcids":["https://orcid.org/0000-0002-6430-9475"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fabr\u00edcio Bitu Sousa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3647,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.59844786,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"67","issue":"1","first_page":"61","last_page":"65"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.054999999701976776,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glanzmann-thrombasthenia","display_name":"Glanzmann thrombasthenia","score":1.0},{"id":"https://openalex.org/keywords/oral-tranexamic-acid","display_name":"oral tranexamic acid","score":0.8880000114440918},{"id":"https://openalex.org/keywords/platelet-transfusion","display_name":"platelet transfusion","score":0.949999988079071},{"id":"https://openalex.org/keywords/bleeding-prevention","display_name":"bleeding prevention","score":0.6850000023841858},{"id":"https://openalex.org/keywords/periodontal-surgery","display_name":"periodontal surgery","score":0.8690000176429749},{"id":"https://openalex.org/keywords/third-molar-surgery","display_name":"third molar extraction","score":0.9800000190734863},{"id":"https://openalex.org/keywords/dental-surgery","display_name":"dental surgery","score":0.4309999942779541},{"id":"https://openalex.org/keywords/bleeding-disorders","display_name":"bleeding disorders","score":0.7250000238418579},{"id":"https://openalex.org/keywords/surgical-planning","display_name":"surgical planning","score":0.515999972820282},{"id":"https://openalex.org/keywords/multidisciplinary-care","display_name":"multidisciplinary care","score":0.8479999899864197}],"concepts":[{"id":"https://openalex.org/C2779637338","wikidata":"https://www.wikidata.org/wiki/Q418666","display_name":"Tranexamic acid","level":3,"score":0.9483604431152344},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.944108784198761},{"id":"https://openalex.org/C2778198917","wikidata":"https://www.wikidata.org/wiki/Q1529258","display_name":"Glanzmann's thrombasthenia","level":5,"score":0.8731517791748047},{"id":"https://openalex.org/C2911156200","wikidata":"https://www.wikidata.org/wiki/Q1529258","display_name":"Thrombasthenia","level":4,"score":0.8138741254806519},{"id":"https://openalex.org/C2910090564","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet disorder","level":3,"score":0.5515366792678833},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5445268154144287},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.5178835391998291},{"id":"https://openalex.org/C2779936836","wikidata":"https://www.wikidata.org/wiki/Q890200","display_name":"Coagulopathy","level":2,"score":0.5020012855529785},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.47712019085884094},{"id":"https://openalex.org/C2776689292","wikidata":"https://www.wikidata.org/wiki/Q23925170","display_name":"Platelet transfusion","level":3,"score":0.46506693959236145},{"id":"https://openalex.org/C2778636310","wikidata":"https://www.wikidata.org/wiki/Q504033","display_name":"Oral and maxillofacial surgery","level":2,"score":0.4276576638221741},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3683810830116272},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.3492920994758606},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1614055335521698},{"id":"https://openalex.org/C2991743468","wikidata":"https://www.wikidata.org/wiki/Q166019","display_name":"Blood loss","level":2,"score":0.11854422092437744},{"id":"https://openalex.org/C2993802102","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet aggregation","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005884","descriptor_name":"Gingival Hemorrhage","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005884","descriptor_name":"Gingival Hemorrhage","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013915","descriptor_name":"Thrombasthenia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D014081","descriptor_name":"Tooth Extraction","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D014148","descriptor_name":"Tranexamic Acid","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D017713","descriptor_name":"Platelet Transfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017742","descriptor_name":"Dental Care for Chronically Ill","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:30644834","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30644834","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General dentistry","raw_type":"Journal Article"},{"id":"mag:2995647250","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30644834","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2891713241","https://openalex.org/W196687191","https://openalex.org/W2529292463","https://openalex.org/W3209445981","https://openalex.org/W2322352056","https://openalex.org/W1993974551","https://openalex.org/W3081763959","https://openalex.org/W4403543749","https://openalex.org/W2461002950","https://openalex.org/W1991366396"],"abstract_inverted_index":{"Glanzmann":[0],"thrombasthenia":[1],"(GT)":[2],"is":[3,179],"a":[4,58,85,155],"rare":[5],"genetic":[6],"disorder":[7],"that":[8],"alters":[9],"platelet":[10,96,157],"function.":[11],"The":[12,147],"clinical":[13],"manifestations":[14],"include":[15],"purpura,":[16],"epistaxis,":[17],"gingival":[18],"bleeding,":[19],"and":[20,70,82,118,136,140,165,198],"menorrhagia.":[21],"For":[22],"patients":[23,44],"with":[24,45,61,84,154],"GT,":[25],"conventional":[26],"surgical":[27,48,194,199],"dental":[28],"treatment":[29],"may":[30],"result":[31],"in":[32,43,161],"hemorrhagic":[33],"complications.":[34],"There":[35],"are":[36],"many":[37],"reported":[38],"ways":[39],"to":[40,89],"prevent":[41],"hemorrhage":[42],"GT":[46,62],"during":[47],"procedures":[49],"but":[50],"no":[51,166],"standardized":[52],"recommendations.":[53],"In":[54],"this":[55,177],"case":[56],"study,":[57],"woman":[59],"diagnosed":[60],"required":[63],"2":[64],"types":[65],"of":[66,92,95,149,185,205],"surgery":[67,69,117],"(periodontal":[68],"third":[71,134,143],"molar":[72],"extractions),":[73],"which":[74,110,188],"were":[75,145,171],"performed":[76,129],"on":[77],"separate":[78],"days.":[79,123],"Preoperative":[80],"evaluation":[81],"planning":[83,200],"hematology":[86],"service":[87],"led":[88],"the":[90,103,131,138,162,203,208],"transfusion":[91],"1":[93,113],"pack":[94],"concentrate":[97],"immediately":[98],"before":[99,115],"each":[100,116],"surgery.":[101,175],"Additionally,":[102],"patient":[104],"was":[105,111,128,159],"prescribed":[106],"oral":[107,150,193],"tranexamic":[108,151],"acid,":[109],"started":[112],"day":[114],"continued":[119],"for":[120,130,192,207],"3":[121],"additional":[122],"A":[124],"distal":[125],"wedge":[126],"procedure":[127],"mandibular":[132,141],"right":[133],"molar,":[135],"later":[137],"maxillary":[139],"left":[142],"molars":[144],"extracted.":[146],"use":[148],"acid":[152],"associated":[153],"single":[156],"bag":[158],"effective":[160],"present":[163],"case,":[164],"bleeding":[167],"or":[168],"thrombotic":[169],"events":[170],"observed":[172],"after":[173],"either":[174],"Although":[176],"coagulopathy":[178],"rare,":[180],"dentists":[181],"must":[182],"be":[183],"aware":[184],"its":[186],"implications,":[187],"necessitate":[189],"specific":[190],"precautions":[191],"procedures.":[195],"Multidisciplinary":[196],"integration":[197],"can":[201],"reduce":[202],"risk":[204],"complications":[206],"patient.":[209]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-12-26T00:00:00"}